Dissecting the interplay between genetic lesions and the tumor microenvironment in Richter Transformation 

Molecular hematology

Dr. Dimitar Efremov, Group Leader of the Molecular Hematology lab at ICGEB Trieste, has been awarded a grant by CLL Global.

The Chronic Lymphocytic Leukemia Global Research Foundation has awarded a grant to Dr. Efremov to support the project to dissect the interplay between genetic lesions and the tumour microenvironment in Richter Transformation.

Group Leader of Molecular Hematology at ICGEB Trieste since 2015, the lab has most recently focused on studying Richter transformation, a rare, aggressive complication in chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that evolves into a fast-growing, high-grade lymphoma, most commonly diffuse large B-cell lymphoma.

Dr. Efremov will conduct future work on this project at the Macedonian Academy of Sciences and Arts in Skopje, North Macedonia.