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pTDP-43S375 immunoreactivity in ALS–TDP. pTDP-43S375 immunohistochemistry robustly labels the complete spectrum of pathological TDP-43 inclusions present in ALS–TDP. Specifically, diffuse and compact neuronal cytoplasmic inclusions (NCI) in the spinal cord

Acta Neuropathologica: Emanuele Buratti’s latest publication moves Frontotemporal dementia studies forward

Aggregation of hyperphosphorylated TDP-43 is the hallmark pathological feature of the most common molecular form of frontotemporal lobar degeneration (FTLD–TDP) and in the vast majority of cases with amyotrophic lateral sclerosis (ALS–TDP). However, most of the specific phosphorylation sites remain to be determined, and their relevance regarding pathogenicity and clinical and pathological phenotypic diversity in FTLD–TDP and ALS–TDP remains to be identified.

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CRP Grant Funding

Outstanding CRP Awards

In the more than 30 years that ICGEB has been providing Funding opportunities through its CRP (Collaborative Research Programme) Grants, reviewers single-out 1 or 2 outstanding proposals particularly worthy of recognition.

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Covid19 testing in Delhi

ICGEB New Delhi steps up for COVID19 testing

To increase the testing capacity for COVID19, the Government of India has asked the research institutes associated with different Government agencies to step-up and contribute to COVID19 testing.

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Massimo Caputi, ICGEB undergraduate in 1991 - now Full Professor at Florida Atlantic University School of Medicine, Boca Raton

Massimo Caputi: Alumni Ambassador of the month

“I stepped inside the ICGEB in Trieste for the first time in 1991; an undergraduate student, with no research experience, looking for a laboratory that would guide me in a small thesis project, which I needed to graduate. It never occurred to me then that the ICGEB would become my home for the next five years.”

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ICGEB online donations

ICGEB was founded to play a key role in Biotechnology worldwide to harness the power of Science and new Technologies to enhance the quality of peoples’ lives worldwide. There is so much more to our Mission than our award-winning, cutting-edge research: we aim to change lives using Science for Development.

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