Arturo Falaschi Conference “2nd biennial conference on TDP-43 function and dysfunction in disease”

The subject areas of the meeting will mostly be concerned with the role played by TDP-43 in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Its involvement in these and other neurodegenerative diseases, such as Alzheimer’s Disease and Parkinson’s Disease, points to TDP-43 as a salient neuropathological protein. As a result, there is growing interest in developing new approaches to understand the consequences of TDP-43 mislocalization and aggregation in disease. Even so, the precise function of TDP-43 in normal cells remains unclear, as are the initial events driving TDP-43 mislocalization and aggregation in disease, and the impact of TDP-43 pathology on neuronal integrity. The meeting organized in Trieste represents an ideal opportunity to discuss ongoing epidemiological, clinical, pathological, neuroimaging, and genetic investigations of this protein. This venue will also serve as a platform for presenting and discussing the latest TDP-43-based therapeutic strategies that are being developed and tested in disease models.

Topics

  • Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) 
  • Events driving TDP-43 mislocalization and aggregation in disease
  • Impact of TDP-43 pathology on neuronal integrity new therapeutic directions

Confirmed Speakers

Todd Cohen, University of North Carolina, USA
Dezerae Cox, University of Wollongong, Australia
Pietro Fratta, University College London, UK
Aaron Gitler, Stanford University, USA
Pallavi Gopal, Yale University, USA
Jenna Gregory, University of Aberdeen, UK
Chris Henstridge, University of Dundee, UK
Sarah Kargbo-Hill, University of Michigan, USA
Masahisa Katsuno, University of Nagoya, Japan
May Khanna, University of Florida, USA
Edward Lee, University of Pennsylvania, USA
Jonathan Ling, Johns Hopkins University, USA
Sarah Marie Mizielinska, King’s College London, UK

Shyamal Mosalaganti, University of Michigan, USA
Leonard Petrucelli, Mayo Clinic, USA
Mercedes Prudencio, Mayo Clinic, USA
Jeffrey Rothstein, Johns Hopkins University, USA
Marc-David Ruepp, King’s College London, UK
Benjamin Ryskedi-Falcon, MRC Laboratory of Molecular Biology, UK
James Shorter, University of Pennsylvania, USA
Shuying Sun, Johns Hopkins University, USA
Jobert Vargas, University College London, UK
Michael Ward, NIH / NINDS, USA
Chris Weihl, Washington University in St Louis, USA

Registration

Registrations WILL BE CONFIRMED ONLY UPON RECEIPT OF THE REGISTRATION FEE

Fees

Early registration by 30 June 2025
Reduced fee*: Euro 450
Regular fee: Euro 650
Registration from 1 July to 20 August 2025
Reduced fee*: Euro 550
Regular fee: Euro 750

* Participants eligible for “Reduced fee” are Students and Post-docs and they must provide proof of qualifying Student or Post-doc status. The mandatory Proof of qualifying student status is a document provided by your University/Affiliated Institute on headed paper, dated, and stamped or signed. Please note that you must be enrolled at the date of the Conference to be eligible for the reduced fee.
Please be informed that if the document is missing, your payment and your participation to the course will NOT be confirmed.

Registration fee includes attendance at the meeting, e-book of abstracts and meals as foreseen in the meeting programme.

Cancellations must be notified to the Organising Secretariat in writing no later than 20 August 2025 (midday Trieste time) and will be subject to a handling fee of Euro 50. After this date refunds cannot be guaranteed.

Accompanying persons are also welcome. The accompanying person’s fee is Euro 210, to include ONLY meals as per programme (will NOT include access to the scientific sessions).

Deadline for registration:
Early bird: 30 June 2025
Regular: 20 August 2025
CALL FOR REGISTRATIONS NOW CLOSED

Meeting Schedule

Monday Sept 8th
16:00-18:00 Registration

Tuesday Sept 9th
8:30-9:30 Registration
9:30-9:40 Welcome address
9:40-11:25 Scientific Session 1
11:25-13:10 Scientific Session 2
13:10-14:10 Lunch
14:10-15:35 Scientific Session 3
15:35-17:15 Scientific Session 4
17:15- 17:35 Coffee break
17:35-18:45 Scientific Session 5
18:45 Group photo
19:00 Welcome reception

Wednesday Sept 10th
9:00-10:45 Scientific Session 6
10:45-11:05 Coffee break
11:05-12:45 Scientific Session 7
12:45-13:45 Lunch
13:45-15:15 Scientific Session 8
15:15-15:35 Coffee break
15:35-17:20 Scientific Session 9
17:20-20:00 Free time
20:00-22:00 Poster session with aperitif

Thursday Sept 11th
8:50-9:00 Winners of poster session announcement
9:00-10:40 Scientific Session 10
10:40-11:00 Coffee break
11:00-12:40 Scientific Session 11
12:40 Closing remarks

Financial Assistance

Nationals of ICGEB Member States are eligible to apply for an ICGEB grant covering registration fee, accommodation and local hospitality for the duration of the Meeting; travel is not funded.

Deadline for applications:
Now extended to 21 May 2025
CALL FOR APPLICATIONS NOW CLOSED

Deadline for financial assistance applications:
Now extended to 21 May 2025

Deadline for abstract submission:
14 July 2025
Short talks will be selected from submitted abstracts

Deadline for registrations:
Early bird – 30 June 2025
Regular – 20 August 2025

Participants

  • PhD and Post-docs in neurodegeneration
  • Clinicians in neurodegenerative diseases
  • Basic scientists in protein aggregation
  • Basic scientists in neurodegeneration pathways

Abstracts

Selected participants will have the opportunity to present their current research. Abstracts will be considered for either oral or poster presentation.
You must REGISTER for the meetings BEFORE you submit your abstract.
Abstracts should be focused on unpublished material.

Deadline for abstract submission: 14 July 2025
Short talks will be selected from the submitted abstracts

Scientific Organisers

Emanuele Buratti (ICGEB Trieste, Italy), Yuna Ayala
(Saint Louis University, MO, USA), Sami Barmada (University of Michigan School of Medicine, Ann Arbor, MI, USA), Christopher Donnelly (University of Pittsburgh School of Medicine, USA) and Jemeen Sreedharan (King’s College London, UK)

Meeting Secretariat

ICGEB Meetings and Courses Unit
Tel: +39-040-3757333 
Fax: +39-040-226555
Email: [email protected]

Meeting location

The Conference will not be held in Trieste City Center, but 20 km away, at Tivoli Portopiccolo Sistiana Resort – consult the map here below for details.

For accommodation availability and prices, you may contact the resort directly or refer to Booking.com for hotel/apartments near Portopiccolo.
Alternatively, 1 or 2 rooms apartments can also be found contactin Portopiccolo Apartments.

PORTOPICCOLO
Str. di Portopiccolo, 231/M
34011 Sistiana TS

In collaboration with

Follow ICGEB events on social media: #ICGEBmeeting