Stephane Heymans

Monday, 5 February 2018 | 12:00 noon

Professor of Cardiomyopathies, Cardiology, Laboratory for Heart Failure Research, Dep. of Cardiology, Maastricht University Medical Centre, CARIM, THE NETHERLANDS

Inflammation and fibrosis as central drivers of heart failure

(Host: M. Giacca)

Cardiologist and Research Scientist since 2003 focusing on the molecular mechanisms of heart failure, looking at the interplay between inflammatory cells, fibroblasts and cardiomyocytes.Unraveled the key role of structural and non-structuralmatrix proteins and RNAs, including microRNAs, matrixmetalloproteinases, collagens and matri-cellular proteins, inmediating cardiac inflammation, fibrosis and dysfunction. Afterhis MD PhD at the university of Leuven, Belgium, and short staysin Berlin, Paris, London and Trieste, Stephane Heymans becamea staff member of Cardiology since 2003 at the MaastrichtUniversity Medical Centre (MUMC), in 2009 appointed professor of (non-ischemic) cardiomyopathies within the Netherlands Heart Institute, the Maastricht University Medical Centre, andthe University of Leuven.

His heart failure research focuses on heart with preserved ejection fraction (HFPEF) and dilatedcardiomyopathies (DCM) (, Linked in. SH is acknowledged for developing a clinical care program andrelated cohorts of non-ischemic CMP, myocarditis and HFPEFpatients at the MUMC (> 1400 patients cohort and biobankof HFPEF and DCM patients with > 12 yrs FU). His programbrings together immunologists, microbiologists, geneticians and molecular cardiologists to study the role of genetics,viruses, inflammation and other environmental factors incardiomyopathies. This clinical works allows a continuous translation between the bench and the bedside.

SH is board member at the European Heart Failure Association, Chair of the Committee on Translational Research of the European Heart Failure Association, Chair of the Working Group of Myocardial Function of the European Society of Cardiology.