Over 600 scientists work in our labs, comprising 46 groups to advance research in the Life Sciences. The labs offer a scientific environment of top international standard, cutting-edge instrumentation, specialised facilities and advanced services.
Many countries in Asia, Africa and Latin America continue to suffer high levels of death and disease caused by infectious agents. The application of modern molecular biology to study human viral and parasitic diseases now offers unprecedented possibilities for developing more accessible diagnostics and novel strategies for effective treatment and prevention. Several Groups in Trieste (TS), New Delhi (ND) and Cape Town (CT) are actively engaged in these areas of research.
There is a growing interest in the ICGEB Member States for research into non-communicable disorders. Understanding the causes of human disease at the genetic and molecular level now enables the development of innovative therapies or preventive measures in fields of enormous importance for public health, such as cardiovascular disorders, cancer and neurodegeneration. Multiple Groups in Trieste, New Delhi and Cape Town are active in these areas.
Applied research and product development in the field of biotechnology is central to the core mission of the ICGEB. This is in parallel with the growing international perception that biotechnology can offer practical and sustainable solutions for the diagnosis and treatment of human disease. Two Groups, one in Trieste and one in New Delhi, have multiple interests in the biomedical field and are developing their research in close collaboration with industries in the ICGEB Member States.
The use of genetic engineering and other modern biological technologies has enormous potential for the production of clean and renewable energy from biological sources. Devising cost-effective processes to produce second-generation biofuels using microalgae, and the identification of novel enzymes effective against the cellulosic biomass are two examples of how energy can be extracted from biological sources. Biotechnology also offers a concrete promise for the development of more effective, sustainable agriculture in the ICGEB Member States.
Plant Biology and Biotechnology
The demand for more effective and sustainable agriculture, able to cope with the exponential increase in the human population and the constraints imposed by current climate changes, is growing in the ICGEB community. Genetic engineering of plants, development of eco-friendly biofertilisers, and other agricultural biotechnologies, together with molecular studies on the resistance of plants to biotic and abiotic stress, are among the most characteristic activities of the ICGEB New Delhi Component and the Bacteriology Group in Trieste (Venturi).
General-use equipment and specialised services are available to the ICGEB research groups. These include resources for cell culture and manipulation; instrumentation for advanced optical microscopy; for advanced protein research and proteomics; a clean-room laboratory for the manufacturing of recombinant pharmaceuticals; a BL3 safety laboratory for handling class 3 pathogens (currently devoted to HIV research); an AAV vector-producing facility occupying a negative-pressurised room with air-locked security; a computer facility dedicated to genomics and biotechnology, allowing access to the most important biological databases and supporting data retrieval and analysis, and a high-throughput facility for whole-genome siRNA and small molecule screen-based on high content microscopy analysis.