Patents and other intellectual property rights are assigned a key role in the achievement of the ICGEB’s objectives.

The Patent Policy remains that of promoting the development, production and wide application of biotechnology, particularly in the interest of developing countries. The ICGEB aims to overcome the difficulties encountered by developing countries in fostering innovation, ownership and in-house application, promoting the transfer of technology and know-how to Member countries.

microRNAs for cardiac regeneration through induction of cardiac myocyte proliferation


Mauro Giacca
Ana Eulalio
Miguel Mano
Serena Zacchigna

23 December 2011

A cellular model for the screening of molecules affecting TDP-43 aggregation

Francisco E. Baralle
Emanuele Buratti
Mauricio Budini

4 November 2011

Antimalarial Agents. US 61/993136
Priority date: 14 January 2014 Inventors: Kotra, L. P., Mohammed A., Malhohtra, P., Chakka, S.K., Wei, L.
Engineering E.coli Strain for conservation of short chain fatty acids to Bioalcohals. 2651/DEL/2013
Priority date: 6 September 2013 Inventors: Yazdani S.S., Mattem, A.J.
A novel method to produce influenza A virus matrix protein M1capsid like particles. 91/DEL/2013
Priority date: 14 January 2013 Inventors: Lal S., Baniasadi, V.
A method for the isolation of small RNAs.  3710/DEL/2012
Priority date: 4 December 2012 Inventors: Mishra, N. S., Mittal D.
Peptides for modulationg drug resistance in yeast. Joint application with JNU.2896/DEL/2012
Priority date: 17 September 2012 Inventors: Maurya, I. K., Tahota, K. C., Sharma, J., Chauhan, V.C., Prasad, R.
Pathways to enhance production of Bioalcohals in Bacteria.  2696/DEL/2012, PCT/IN2013/000535
Priority date: 30 August 2012 Inventors: Yazdani S.S., Munjal, N., Mattem, A.J.
Novel cellulolytic enzymes and their Chimera.  2695/DEL/2012
Priority date: 30 August 2012 Inventors: Yazdani S.S, Adlakha, N.
Method for stable expression of suppressors off RNAI in plants by direct genetic transformation of seeds.  2694/DEL/2012, US 14/015018
Priority date: 30 August 2012 Inventors: Mishra, S. N., Das, S. S.
Modified Amphipathic dipeptide based assembled nanoparticles: vehicles for targeted tumor drug delivery. 2612/DEL/2012
Priority date: 23 August 2012 Inventors: Chauhan, V.S.
Novel compositions for the treatment and prevention of malaria. 177/DEL/2012
Priority date: 20 January 2012 Inventors: Chauhan, V.S., Shadab J.J. 
Pichia pastoris-expressed Dengue envelope-based virus like particles as safe, efficacious and inexpensive dengue subunit vaccine. 1663/DEL/2011
Priority date: 13 June 2011 Inventors: Mani, S., Tripathi, L., Kartik, D., Khanna, N., Swaminathan, S., Tyagi, P.
Envelope Domain III based Dengue vaccine candidate using Hepatitis B virus core antigen virus like particles as modular display system. 1662/DEL/2011
Priority date: 13 June 2011 Inventors: Arora, U., Tyagi, P., Khanna, N, Swaminathan, S.
Combinations of multiple molecular target inhibitors for treatment of abnormal cell growth. 1650/DEL/2011
Priority date: 1 June 2011 Inventors: Rao, K., Jailkhani, N., Ravichandran, S.
Carbon-nanotube applications to modify electro-mechanical properties of cardiac myocytes. Joint application with University of Colorado and University of Trieste. PCT/U52012128930
Priority date: 14 March 2011 Inventors: L. Mestroni, C. Long, J. Caldwell, L. Ballerini, M. Prato, G. Cellot, F.M. Toma, V. Martinelli, L. Zentilin.
Novel Composition for eliminating, reducing or retarding growth of drug resistant myco-bacteria. Joint application with Sphaera Pharma Pvt. Ltd. 547/DEL/2011
Priority date: 1 March 2011 Inventors: Rao, K., Verma, D.K., Singh, V.
Novel host factor as therapeutic targets for development of anti-tubercolosis. Joint application with Sphaera Pharma Pvt. Ltd. 548/DEL/2011
Priority date: 1 March 2011 Inventors: Rao, K., Verma, D.K., Singh, V.
Novel Composition for treatment of multi drug resistant mycobacterial infection. Joint application with Sphaera Pharma Pvt. Ltd. 546/DEL/2011
Priority date: 1 March 2011 Inventors: Rao, K., Verma, D.K., Singh, V.
Novel Composition for tuberculosis. Joint application with Sphaera Pharma Pvt. Ltd. 545/DEL/2011
Priority date: 1 March 2011 Inventors: Rao, K., Verma, D.K., Singh, V.
Immunotherapy of Infectious Diseases. 124/DEL/2011
Priority date: 19 January 2011 Inventors: Das, G., Majumdar, T., Rao, K.
Recombinan proteins with selective inactivation activity in target proteins.
Priority date: 25 November 2010 Inventors: Oscar Burrone, Marco Bestagno, Lara Vecchi
Plant Cell Wall Hydrolyzing Enzymes Insect Mid-Gut Bacterium. 2071/DEL/2010
Priority date: 31 August 2010 Inventors: Yazdani, S.S., Adlakha, N.
Envelope domanin III based dengue vaccine candidate using HBsAg virus like particles as modular display system. 1820/DEL/2010
Priority date: 2 August 2010 Inventors: Khanna, N., Swaminathan, S., Dhar, N., Patil, A., Perween, G.C., Gurramkonda, G., Tyagi, P., Raut, R.
De novo designed cationic amphipathic antibacterial peptides. 1327/DEL/2010
Priority date: 8 June 2010 Inventors: Chauhan, V.S., Pathak S., Gupta, M.
Peptides and their derivatives inhibiting extracellular release of HIV-1 TAT Protein and HIV-1 Replication
Priority date: 10 December 2009 Inventors: Giacca, M., Agostini, S.
An anti-malarial vaccine. 1814/DEL/2009
Priority date: 3 September 2009 Inventors: Chitnis, C., Singh, S., Alam, M.
Anticancer agent specific for brain tumors with mechanism of RECQ1 suppression
Priority date: 29 June 2009 Inventors: Vindigni, A., Mendoza-Maldonado, R., Faoro, V., Odreman, F., Berti, M., Vindigni, M., Bonin, S., Skrap, M., Stanta, G.
Anti dengue activity of Cissampelos pariera extracts. Joint application ICGEB – Ranbaxy Research Laboratory
Priority date: 23 January 2009 Inventors: Bhatnager, P.K., Katiyar, C.K., Khanna, N., Upadhyay, D.J., Swaminathan, S., Srinivas, K., Sharma, N., Kanaujia, A., Sood, R., Singhal, S., Shukla, G., Duggar, R., Pareek, P.K., Singh, Y., Khan, S., Raut, R.
Pharmaceutical compositions containing calcium channel blockers for treatment of Tuberculosis
Priority date: 5 September 2008 Inventors: Gupta, S., Singla, R., Behera, D., Khayyam, K.U., Korde, R., Malhotra, P., Natarajan K.
Screening and identification of novel host factors as therapeutic targets for design and development of anti tuberculosis drugs and process thereof. 2089/DEL/2008 & 94/DEL/2009
Priority date: 4 September 2008 Inventors: Rao, K.V.S., Jayaswal, S., Kamal, M.A., Kumar, D.
Use of small peptides corresponding to protein-protein interface residues of Plasmodium falciparum ClpQ protease (PfClpQ) and ClpY ATPase (PfClpY) or small drug like molecules designed based upon these peptides that interface with interaction of PfClpQ and PfClpY, as anti-malarial drugs. 2057/DEL/2008
Priority date: 1 September 2008 Inventors: Rathore, S., Sinha, D., Chauhan, V.S., Gupta, D., Mohammed, A.
Peptide from proregion of proteases inhibition of parasitic and infectious organisms. 1863/DEL/2008
Priority date: 6 August 2008 Inventors: Malhotra, P., Korde, R., Bhatnagar, R., Chauhan, V.S.
Use of a novel plasmodium falciparum merozoite apical protein as malaria vaccine. 1844/DEL/2008
Priority date: 4 August 2008 Inventors: Mohammed, A., Chauhan, V.S.
A fusion protein malaria vaccine consisting of Plasmodium falciparum merozoite surface protein 1 and plasmodium falciparum merozoite surface protein 3. 1737/DEL/2008
Priority date: 23 July 2008 Inventors: Mazumdar, S., Yazdani, S.S., Mohammed, A., Chauhan, V.S
A method for rapid and high frequency of regeneration of genetically transformed calli of Indica rice cultivar. 1736/DEL/2008
Priority date: 23 July 2008 Inventors: Singla-Pareek, S.L., Kumar, K., Sopory, S.K
Self Assembled hydrogel containing α, β- dehydrophenyalanine residue (PHE) and process for preparation thereof. 1735/DEL/2008
Priority date: 23 July 2008 Inventors: Panda, J.J., Mishra, A., Chauhan, V.S
Enzymatic composition of novel peptide(s) and protease(s) for degrading protease resistant proteins. 260/DEL/2008
Priority date: 30 January 2008 Inventors: Bhatnagar, R., Gupta, R., Arora, N., Ramani, P.
A humanized high affinity recombinant antibody against hepatitis B surface antigen. Joint application with All India Institute of Medical Sciences (AIIMS)
Priority date: 23 January 2008 Inventors: Tiwari, A., Sinha, S., Khanna, N., Acharya, S.K.
A novel dengue envelope domain III – based tetravalent protein vaccine
Priority date: 12 June 2007 Inventors: Khanna, N., Sathyamangalam, S.
A recombinant mouse-human chimeric Fab against Hepatitis B surface antigen. Joint application with 1. Department of Biotechnology (DBT), 2. All India Institute of Medical Sciences (AIIMS)
Priority date: 18 December 2006 Inventors: Sinha, S., Bose, B., Khanna, N., Acharya, S.K.
A virus-like particle (VLP) candidate vaccine for hepatitis E produced in Escherichia coll. 2040/DEL/2006
Priority date: 15 September 2006 Inventors: Jameel, S.A., Yazdani, S., Pani, B., Ganti, K.P., Khan, S.A.
Conformationally restricted alpha, beta-dehydrophenylalanine residue and its use in design of peptide nanotubes. 2382/DEL/2006
Priority date: 1 November 2006 Inventors: Chauhan, V.S., Gupta, M., Mishra, A.
Development of MY MIV based gene silencing vectors. 1267/DEL/2006
Priority date: 25 May 2006 Inventors: Mukherjee, S.K.
Tetravalent Dengue specific domain III based chimeric recombinant protein as dengue diagnostic intermediated of high specificity for detenction of both dengue IgM. 2539/DEL/2005
Priority date: 20 September 2005 Inventors: Khanna, N., Swaminathan, S., Batra, G., Hapugoda, M.
A pharmaceutical composition useful for the treatment of hepatocellular carcinoma. Joint application with CSIR
Priority date: 26 May 2005 Inventors: Saxena, A.K., Gupta, B.D., Kapahi, B.K., Shanmugavel M., Mondhe, D.M., Qazi, G.N., Mathan, G., Kumar, V.
De novo designated and synthesized cationic amphipathic peptides
Priority date: 25 May 2005 Inventors: Sahal, D., Chetal, P., Ananthanaram, A., Chauhan, V.S.
A Method of treating a plant to make it salt tolerant; a vector for use in the said treatment and its sequence thereof. 1340/DEL/2005
Priority date: 25 May 2005 Inventors: Bhattacharjee, B., Nair, S., Mohan, M., Vashisht, A.A., Tuteja, N.
A novel selectable marker system for transgenic plants. 2618/DEL/2004
Priority date: 31 December 2004 Inventors: Singla-Pareek, S.L, Yadav, S.K., Reddy, M.K., Sopory, S.K.
A new antifungal protein isolated from the seeds of chickpea, methods for isolation of such proteins, cloning of the encoding gene and transgenic plants incorporating such genes
Priority date: 31 December 2004 Inventors: Reddy, V.S., Hassairi, A., Islam, A.
Regeneration of plants and medium for use thereof. 1602/DEL/2004
Priority date: 26 August 2004 Inventors: Bhattacharjee, B., Nair, S., Mohan, M.
Extration of latex of Calotropis procera and a process for the praparation thereof. Joint application with All India Institute of Medical Sciences (AIIMS). 737/DEL/2004
Priority date: 19 April 2004 Inventors: Kumar, V.L., Kumar, V.
Biopesticides for controlling inter alia sugarcane pests. Joint application with PDKV
Priority date: 15 December 2003 Inventors: Bhatnagar, R.K., Rajagopal, R., Rao, N.G.V.
Overexpression of foreign genes in plants
Priority date: 18 September 2003 Inventors: Reddy, V.S., Leelavathi, S., Nguyen, H.T.
Novel recombinant dengue multiepitope (r-DME) proteins as diangostic intermediates. Joint application with DRDO
Priority date: 7 August 2003 Inventors: Khanna, N., Ananda Rao, R., Jana, A.M.
Conscious evolution of proteins through codon huffling. 609/DEL/2003
Priority date: 16 April 2003 Inventors: Ranganathan, A., Chopra, S.
Method for screening a candidate substance as a potential drug for the treatment of malaria
Priority date: 1 July 2002 Inventors: Sahal, D., Kannan, R., Chauhan, V.S.
A method for preparing scar primers for use in marker assisted selection of rice varieties susceptible to attack by Gall Midge biotypes; method for preparing the same and method for screening rice varieties – LICENSED
Priority date: 17 October 2001 Inventors: Mohan, M., Nair, S., Kumar, A., Sandesai, N.
Process for xykanase production. Joint application with IMTECH
Priority date: 2 August 2001 Inventors: Reddy, V.S., Leelavathi, S., Gupta, N., Maiti, S., Ghosh, A.
Priority date: 3 August 1999 Inventors: Baralle, F.E., Fló, J., Tisminetzky,S
A bicistronic DNA construct comprising X-myc transgene for use in production of transgenic animal model systems for human hepatocellular carcinoma and transgenic animal model systems so produced. Joint application with NII
Priority date: 23 September 1998 Inventors: Kumar, V., Singh, M., Totey, S.M., Anand, R.K
Screening Method for determining individuals at risk of developing diseases associated with different polymorphic forms of wildtype p53
Priority date: 22 September 1997 Inventors: Matlashewski et al.
Process for the preparation of very high purity gamma interferon
Priority date: 11 September 1995 Inventors: Khanna N.

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