Naseem A. Gaur

Group Leader,
Yeast Biofuel
International Centre for Genetic Engineering and Biotechnology
ICGEB-DBT Advanced Bioenergy Research
Aruna Asaf Ali Marg
110 067 New Delhi, India
E-mail: [email protected]
Tel:  +91-11-26741358 ext 452

Education

Jawaharlal Nehru University /Jamia Millia Islamia University New Delhi, Ph.D., 2005
Jamia Millia Islamia University, New Delhi, M.Sc. (Bio-Sciences), 1999
Jamia Millia Islamia University, New Delhi, B.Sc. (Bio-Sciences), 1997

Career History

2015-Present: Group Leader, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India
2012- 2015: Research Scientist and Ramanujan Fellow, ICGEB New Delhi
2010-2012: Research Fellow, National Institutes of Health (NIH), Bethesda, Maryland, USA
2007-2010: Postdoctoral Research Fellow, National Institutes of Health (NIH), Bethesda, Maryland, USA
2005- 2007: Postdoctoral Research Fellow, BWH, Harvard University, Boston, MA, USA

Scientific Activity

Current research interest focuses on developing yeast strains for bio-based chemical production including, bio-alcohols and oleochemicals, Xylo-oligosaccharides, Xylitol and recombinant protein expression. He also maintains a strong interest in the field of human fungal pathogenesis and multidrug resistance.

Research activities are funded through grants from various public and private bodies, including the Department of Science and Technology (DST) and Department of Biotechnology (DBT), Ministry of Science and Technology, Government of India.

Naseem Gaur regularly reviews scientific manuscripts for international journals in the fields of biofuels, Gene expression, multidrug resistance and grant applications in the context of biotechnology. Over 20 papers in peer-reviewed international journals and 5 reviews or chapters in published books. He regularly presents his research activity at meetings and seminars worldwide.

Since 2017 – Radio Safety Officer (RSO), ICGEB, New Delhi

Teaching Activity

Tutoring activities in the ICGEB PhD Programme

Since 2016 – Teaching ‘Transcriptional network and yeast synthetic biology’ as part of ‘Synthetic and Systems Biology’ Course
Since 2015 – Teaching ‘Gene expression in yeast’ as part of ‘Research Methodology’ Course

Selected publications

  • Deeba, F., Kumar, K. K., Wani, S. A., Kumar, A. K., Sharma, J., Gaur, N. A. (2022). Enhanced biodiesel and β-carotene production in Rhodotorula pacifica INDKK using sugarcane bagasse and molasses by an integrated biorefinery framework. Bioresource Technology. 127067. doi: 10.1016/j.biortech.2022.127067. PMID: 35351564
  • Sharma, J., Kumar, V., Prasad, R., Gaur, N.A. (2022). Engineering of Saccharomyces cerevisiae as a consolidated bioprocessing host to produce cellulosic ethanol: Recent advancements and current challenges. Biotechnology Advances. 56:107925. doi: 10.1016/j.biotechadv.2022.107925. PMID: 35151789 
  • Kumari, S., Kumar, M., Esquivel, B. D., Wasi, M., Pamdey, A. K., Khandelwal, A. K., Mondal, A. K., White. T. C., Prasad, R., Gaur, N. A. (2022). Unmasking of CgYor1-Dependent Azole Resistance Mediated by Target of Rapamycin (TOR) and Calcineurin Signaling in Candida glabrata. mBio. 18;13(1):e0354521. doi: 10.1128/mbio.03545-21. PMID: 35038899 
  • Pandey, A. K., Kumar, M., Kumari, S., Gaur, N. A. (2022). Integration of acid pre-treated paddy straw hydrolysate to molasses as a diluent enhances ethanol production using a robust Saccharomyces cerevisiae NGY10 strain. Renewable Energy. 186; 790-80. https://doi. org/10.1016/j.renene.2022.01.039
  • Deeba, F., Kumar, K. K., Rajacharya, H. R., Gaur, N. A. (2021). Metabolomic Profiling Revealed Diversion of Cytidinediphosphate-Diacylglycerol and Glycerol Pathway towards Denovo Triacylglycerol Synthesis in Rhodosporidium toruloides. Journal of  Fungi (Basel). 13;7(11):967. doi: 10.3390/jof7110967. PMID: 34829254
  • Onchieku. N. M., Kumari. S., Pandey. R., Sharma. V., Kumar. M., Deshmukh. A., Kaur. I., Mohmmed. A., Gupta. D., Kiboi. D., Gaur. N. A., Malhotra. P. (2021). Artemisinin Binds and Inhibits the Activity of Plasmodium falciparum Ddi1, a Retroviral Aspartyl Protease. Pathogens. 10(11):1465. doi: 10.3390/ pathogens 10111465. PMID: 34832620 
  • Kumar, M., Singh, A., Kumari, S., Kumar, P., Wasi, M., Mondal, A. K., Rudramurthy, S. M., Chakrabarti, A., Gaur N. A*, Gow, N. A. R., Prasad, R*. (2021). Sphingolipidomics of drug resistant Candida auris clinical isolates reveal distinct sphingolipid species signatures. BBA Mol Cell Biol Lipids. 1866(1):158815. doi:10.1016/j.bbalip.2020.158815. PMID: 32942047 (*corresponding authors)
  • Kumar, K. K., Deeba, F., Suraj., Negi, Y. S., Gaur, N. A. (2020). Harnessing pongamia shell hydrolysate for triacylglycerol agglomeration by novel oleaginous yeast Rhodotorula pacifica INDKK. Biotechnoly for Biofuels. 13:175. doi: 10.1186/ s13068-020-01814-9. eCollection 2020. PMID: 33088345
  • Muzafar, S.,  Sharma, R. D., Shah, A, H., Gaur, N. A., Dasgupta, U., Chauhan, N., Prasad, R. (2020). Identification of Genomewide Alternative Splicing Events in Sequential, Isogenic Clinical Isolates of Candida albicans Reveals a Novel Mechanism of Drug Resistance and Tolerance to Cellular Stresses. mSphere. 5(4):e00608-20. doi: 10.1128/ mSphere.00608-20.PMID: 32817456
  • Kumari, S., Kumar, M., Khandelwal, N. K., Pandey, A. K., Bhakt, P., Kaur, R., Prasad, R., Gaur, N. A. (2020). A homologous overexpression system to st`udy roles of drug transporters in Candida glabrata. FEMS Yeast Res. 20(4):foaa032. doi: 10.1093/femsyr/ foaa032.

Book Chapters

Yusuf, F., Gaur, N.A. 2017. Engineering Saccharomyces cerevisiae for C5 fermentation: A step towards second generation biofuel production “Metabolic engineering for bioactive compounds” Published by Springer

Kumari, P., Yusuf, F., Gaur, N. A. 2019. Novel microbial modification tools to convert lipids into other value added products. Methods Mol Biol. 1995:161-171. DOI: 10.1007/978-1-4939-9484-7_10. Pubmed link