Naseem A. Gaur

Group Leader,
Yeast Biofuel

International Centre for Genetic Engineering and Biotechnology
ICGEB-DBT Advanced Bioenergy Research
Aruna Asaf Ali Marg
110 067 New Delhi, India
E-mail: [email protected]
Tel:  +91-11-26741358 ext 452

Education

Jawaharlal Nehru University /Jamia Millia Islamia University New Delhi, Ph.D., 2005
Jamia Millia Islamia University, New Delhi, M.Sc. (Bio-Sciences), 1999
Jamia Millia Islamia University, New Delhi, B.Sc. (Bio-Sciences), 1997

Career History

2015-Present: Group Leader, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India
2012- 2015: Research Scientist and Ramanujan Fellow, ICGEB New Delhi
2010-2012: Research Fellow, National Institutes of Health (NIH), Bethesda, Maryland, USA
2007-2010: Postdoctoral Research Fellow, National Institutes of Health (NIH), Bethesda, Maryland, USA
2005- 2007: Postdoctoral Research Fellow, BWH, Harvard University, Boston, MA, USA

Scientific Activity

Current research interest focuses on developing yeast strains for bio-based chemical production including, bio-alcohols and oleochemicals, Xylo-oligosaccharides, Xylitol and recombinant protein expression. He also maintains a strong interest in the field of human fungal pathogenesis and multidrug resistance.

Research activities are funded through grants from various public and private bodies, including the Department of Science and Technology (DST) and Department of Biotechnology (DBT), Ministry of Science and Technology, Government of India.

Naseem Gaur regularly reviews scientific manuscripts for international journals in the fields of biofuels, Gene expression, multidrug resistance and grant applications in the context of biotechnology. Over 20 papers in peer-reviewed international journals and 5 reviews or chapters in published books. He regularly presents his research activity at meetings and seminars worldwide.

Since 2017 – Radio Safety Officer (RSO), ICGEB, New Delhi

Teaching Activity

Tutoring activities in the ICGEB PhD Programme

Since 2016 – Teaching ‘Transcriptional network and yeast synthetic biology’ as part of ‘Synthetic and Systems Biology’ Course
Since 2015 – Teaching ‘Gene expression in yeast’ as part of ‘Research Methodology’ Course

Selected publications

Kumar, K. K., Deeba, F., Suraj., Negi, Y. S., Gaur, N. A. 2020. Harnessing pongamia shell hydrolysate for triacylglycerol agglomeration by novel oleaginous yeast Rhodotorula pacifica INDKK. Biotechnology for Biofuels. 13: 175. DOI: 10.1186/s13068-020-01814-9 Pubmed link

Muzafar, S.,  Sharma, R. D., Shah, A, H., Gaur, N. A., Dasgupta, U., Chauhan, N., Prasad, R. 2020. Identification of genome wide alternative splicing events in sequential, isogenic clinical isolates of candida albicans reveals a novel Mechanism of drug resistance and tolerance to cellular stresses. mSphere. 5(4):e00608-20. DOI: 10.1128 /mSphere. 00608-20. Pubmed link

Kumari S, Kumar M, Khandelwal NK, Pandey AK, Bhakt P, Kaur R, Prasad R, Gaur NA. 2020. A homologous overexpression system to study roles of drug transporters in Candida glabrata. FEMS Yeast Res. 20(4):foaa032. DOI: 10.1093/femsyr/ foaa032. Pubmed link

Pandey, A. K., Kumar, M., Kumari, S., Jakeer, S., Naz, S., Chandna, P., Bhatnagara, I., Kumari, P., Yusuf, F., Gaur, N. A. 2019. Evaluation of divergent yeast genera for fermentation associated stresses and identification of a robust sugarcane distillery waste isolate Saccharomyces cerevisiae NGY10 for lignocellulosic ethanol production in SHF and SSF. Biotechnology for Biofuels. 12:40. DOI: 10.1186/s13068-019-1379. Pubmed link

Khandelwal, N. K., Chauhan, N., Sarkar, P., Esquivel, B. D., Coccetti, P., Singh, A., Coste, A. T., Gupta, M., Sanglard, D., White, T. C., Chauvel, M., d’Enfert, C., Chattopadhyay, A., Gaur, N. A., Mondal, A. K., Prasad, R. 2018. Azole resistance in a candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signalling. J Biol Chem. 293(2):412-432. DOI: 10.1074/jbc.M117.807032. Pubmed link

Gaur N. A., Hasek J, Garvey Brickner D, Qiu H, Zhang F, Wong CM, Malcova I, Vasicova P, Brickner JH, Hinnebusch A. 2013. Vps Factors are Required for Efficient Transcription Elongation in Budding Yeast. Genetics. 193(3):829-51. Pubmed link

Qiu, H. Hu, C., Gaur, N. A., and Hinnebusch, A. G. 2012. Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex. EMBO J. 15;31(16):3494-505. Pubmed link

Mousley, C. J. Yuan, P., Gaur, N. A., TrettinK. D., Nile, A. H., Dewar, B., Deminoff, S., Herman, P.K., Hinnebusch, A. G., Macdonald, J. M.,and Bankaitis, V. A. 2012. A sterol binding protein integrates endosomal lipid metabolism with TOR signaling and nitrogen sensing. Cell. 148 (4): 702-715 DOI: 10.1016/j.cell.2011.12.026. PubMed link

Gaur, N. A., Zhang, F., Hasek, J., Kim, S., Qiu, H., Swanson, M. J., and Hinnebusch, A. G., 2008. Disrupting Vesicular Trafficking at the Endosome Attenuates Transcriptional Activation by Gcn4. Mol Cell Biol. 28(22), 6796-818. DOI: 10.1128/ MCB.00800-08. Pubmed link

Sadler, K. C., Krahn, K. N., Gaur, N. A., and Ukomadu, C. 2007. Liver growth in the embryo and during liver regeneration in Zebrafish requires the cell cycle regulator, uhrf1. PNAS. (USA) 104(5), 1570-5. Proc Natl Acad Sci U S A. 104(5):1570-5. DOI: 10.1073/pnas.0610774104. Pubmed link

Book Chapters

Yusuf, F., Gaur, N.A. 2017. Engineering Saccharomyces cerevisiae for C5 fermentation: A step towards second generation biofuel production “Metabolic engineering for bioactive compounds” Published by Springer

Kumari, P., Yusuf, F., Gaur, N. A. 2019. Novel microbial modification tools to convert lipids into other value added products. Methods Mol Biol. 1995:161-171. DOI: 10.1007/978-1-4939-9484-7_10. Pubmed link