Friday, 9 September 2022 | 12.00 noon – ICGEB Trieste, ITALY
University of Chile, Faculty of Dentistry, Independencia Santiago, CHILE
Role of chaperone mediated autophagy (CMA) in neurodegenerative, metabolic, and oral processes
Chaperone mediated autophagy (CMA) is a lysosomal autophagic pathway that specifically degrades proteins containing at least one motif related with the amino acidic sequence KFERQ. Around 75% of the human proteome contain the KFERQ-like motifs, therefore, CMA can impact on multiple biological processes. Dr. Budini’s lab studies the CMA molecular mechanisms and biological functions involved in health and disease. In this seminar, Dr. Budini will talk about how CMA activity can impact on particular neurodegenerative, metabolic, and oral processes.
Dr. Mauricio Budini is Molecular Biologist from the National University of San Luis, San Luis, Argentina. In 2008 he received his Ph.D. degree in Biomedical Sciences from the Faculty of Medicine, University of Chile, Chile and then developed a postdoc training in the Molecular Pathology Laboratory at the ICGEB, Trieste, Italy. Since 2014, Dr. Budini is Assistant Professor in the Institute for Dental Research, at the Faculty of Dentistry, University of Chile, Chile