Publications

Genomic Sequencing

Mekonnen F, Khan BA, Nibret E, Munshea A, Tsega D, Endalamaw D, Tadesse S, Yismaw G, Lankir D, Ali J, Ulinici M, Orsini E, Susnjar U, Carletti T, Licastro D, Bitew M, Giovanetti M, Marcello A. Introduction of Dengue Virus Serotype 3 in the Afar Region, Ethiopia. Emerg Microbes Infect. 2024, doi: 10.1080/22221751.2024.2429653

Cella E, Fonseca V, Branda F, Tosta S, Moreno K, Schuab G, Ali S, Slavov SN, Scarpa F, Santos LA, Kashima S, Wilkinson E, Tegally H, Mavian C, Borsetti A, Caccuri F, Salemi M, de Oliveira T, Azarian T, de Filippis AMB, Alcantara LCJ, Ceccarelli G, Caruso A, Colizzi V, Marcello A, Lourenço J, Ciccozzi M, Giovanetti M. Integrated analyses of the transmission history of SARS-CoV-2 and its association with molecular evolution of the virus underlining the pandemic outbreaks in Italy, 2019-2023. Int J Infect Dis. 2024, doi: 10.1016/j.ijid.2024.107262.

Ulinici M, Soñora M, Orsini E, Licastro D, Dal Monego S, Todiras M, Lungu L, Groppa S, Marcello A. Genome Sequences of SARS-CoV-2 Strains from the Republic of Moldova. Microbiol Resour Announc. 2023, doi: 10.1128/mra.01132-22

Branda F, Nakase T, Maruotti A, Scarpa F, Ciccozzi A,  Romano C,  Peletto S,  Bispo de Filippis AM, Alcantara LCJ, Marcello A,  Ciccozzi M,  Lourenço J,  Giovanetti M. Dengue virus transmission in Italy: surveillance and epidemiological trends up to 2023. medRxiv 2023, doi: https://doi.org/10.1101/2023.12.19.23300208

Bitew M, Hailu G, Tsegay Y. G, Tuki K, Asmamaw K, Tesfaye K, Dadi H, Orsini E, Dal Monego S, Licastro D, Marcello A. SARS-CoV-2 Genome Sequence Obtained from Ethiopia, Microbiol Resour Announc. 2022, doi: 10.1128/mra.01182-21

Paulino-Ramirez R, Riego E, Vallejo-Degaudenzi A, Calderon V. V, TapiaL, León P, Licastro D., Dal Monego S, Rajasekharan S, Orsini E, Marcello A. Whole-Genome Sequences of SARS-CoV-2 Isolates from the Dominican Republic, Microbiol Resour Announc. 2021, doi: 10.1128/MRA.00952-21

Giovanetti M, Cella E, Benedetti F, Rife Magalis B, Fonseca V, Fabris S, Campisi G, Ciccozzi A, Angeletti S, Borsetti A, Tambone V, Sagnelli C, Pascarella S, Riva A, Ceccarelli G, Marcello A, Azarian T, Wilkinson E, de Oliveira T, Alcantara L. C. J, Cauda R, Caruso A, Dean N. E, Browne C, Lourenco J, Salemi M, Zella D, Ciccozzi M. SARS-CoV-2 shifting transmission dynamics and hidden reservoirs potentially limit efficacy of public health interventions in Italy, Comm. Biol. 2021, doi: 10.1038/s42003-021-02025-0

Al-Rashedi N. A. M, Licastro D, Rajasekharan S, Dal Monego S, Marcello A, Munahi M. G, Odda B. S, Alabdali Y. A. J, AlObaidi L. A. H, Jasim A, Abdulzahra I. A, Kadhim K, Awad A, Bachay M. Genome Sequencing of a Novel Coronavirus SARS-CoV-2 Isolate from Iraq, Microbiol Resour Announc. 2021, doi: 10.1128/MRA.01316-20

Alm E, Broberg E. K, Connor T, Hodcroft E. B, Komissarov A. B, Maurer-Stroh S, Melidou A, Neher R. A, O’Toole Á, Pereyaslov D, WHO European Region sequencing laboratories and GISAID EpiCoV group. Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020. Euro Surveill. 2020, doi: 10.2807/1560-7917.ES.2020.25.32.2001410

Licastro D, Rajasekharan S, Dal Monego S, Segat L, D’Agaro P, Marcello A. Isolation and Full-Length Genome Characterization of SARS-CoV-2 from COVID-19 Cases in Northern Italy, J Virol. 2020, doi: 10.1128/JVI.00543-20

Diagnostics

Šušnjar U, Bitew M, Ayele S, Uršič T, Petrovec M, Carletti T, Bussani E, De Conti L, Mekonnen F, Baba MM, Agola EL, Chimpolo MM, Van-Dúnem JCV, Tarnagda Z, Kakou-Ngazoa S, Wade D, Maeka KK, Mustafa M, Raycheva R, Kaseya J, Ndembi N, Fokam J, Marcello A; EXPANDIA Working Group. Colorimetric RT-LAMP for SARS-CoV-2 detection from nasopharyngeal swabs or crude saliva: a multicountry diagnostic accuracy study in Africa. Lancet Glob Health. 2025 Jul;13(7):e1258-e1267. doi:  10.1016/S2214-109X(25)00150-0 .

Ulinici M, Suljič A, Poggianella M, Milan Bonotto R, Resman Rus K, Paraschiv A, Bonetti AM, Todiras M, Corlateanu A, Groppa S, Ceban E, Petrovec M, Marcello A. Characterisation of the Antibody Response in Sinopharm (BBIBP-CorV) Recipients and COVID-19 Convalescent Sera from the Republic of Moldova. Vaccines (Basel). 2023, doi: 10.3390/vaccines11030637.

Oderinde BS, Shuaibu ZA, Okoye CP, Audu MI, Mora Cardenas E, Carletti T, Marcello A, Awi TG, Buba JR and Baba MM. Multiple serotypes of Dengue unmasked from suspected malaria patients are significantly associated with yellow fever vaccination in northeastern Nigeria. American Journal of Epidemiology and Infectious Disease, 2022 doi:10.12691/ajeid-10-1-2

Baba M. M, Bitew M, Fokam J, Lelo E. A, Ahidjo A, Asmamaw K, Beloumou G. A, Bulimo W. D, Buratti E, Chenwi C, Dadi H, D’Agaro P, De Conti L, Fainguem N, Gadzama G, Maiuri P, Majanja J, Meshack W, Ndjolo A, Nkenfou C, Oderinde B. S, Opanda S. M, Segat L, Stuani C, Symekher S. L, Takou D, Tesfaye K, Triolo G, Tuki K, Zacchigna S, Marcello A. Diagnostic performance of a colorimetric RT -LAMP for the identification of SARS-CoV-2: A multicenter prospective clinical evaluation in sub-Saharan Africa. EClinicalMedicine 2021, doi: 10.1016/j.eclinm.2021.101101

Lombardo F, Triolo G, Yang B, Liu Z, Maiuri P, Orsini E, Jin W, Zacchigna S, Marcello A. Diagnostic Performance of a Rapid Antigen Test Compared with the Reverse Transcription Polymerase Chain Reaction for SARS-CoV-2 Detection in Asymptomatic Individuals Referring to a Drive-in Testing Facility COVID 2021, doi: 10.3390/covid1040063

Oderinde BS, Mora-Cárdenas E, Carletti T, Baba MM, Marcello A. Prevalence of locally undetected acute infections of Flaviviruses in North-Eastern Nigeria. Virus Res. 2020, doi: 10.1016/j.virusres.2020.198060

Caracciolo I, Mora-Cardenas E, Aloise C, Carletti T, Segat L, Burali MS, Chiarvesio A, Totis V, Avšič-Županc T, Mastrangelo E, Manfroni G, D’Agaro P, Marcello A. Comprehensive response to Usutu virus following first isolation in blood donors in the Friuli Venezia Giulia region of Italy: Development of recombinant NS1-based serology and sensitivity to antiviral drugs. PLoS Negl Trop Dis. 2020, doi: 10.1371/journal.pntd.0008156

Mora-Cárdenas E, Aloise C, Faoro V, Knap Gašper N, Korva M, Caracciolo I, D’Agaro P, Avšič-Županc T, Marcello A. Comparative specificity and sensitivity of NS1-based serological assays for the detection of flavivirus immune response. PLoS Negl Trop Dis. 2020 doi: 10.1371/journal.pntd.0008039

Therapy

Baroni S, Carletti T, Donalisio M, Arduino I, Cazzaniga I, Giorgino T, Esposito F, Porta A, Diomede L, De Luigi A, Gobbi M, Lembo D, Marcello A, Tramontano E, Milani M and Mastrangelo E. The antipsychotic drug lurasidone inhibits coronaviruses by affecting multiple targets. Front. Cell. Infect. Microbiol, 2024. doi: 10.3389/fcimb.2024.1487604

Abreu C, Ortega C, Olivero-Deibe N, Carrión F, Gaete-Argel A, Valiente-Echeverría F, Soto-Rifo R, Milan Bonotto R, Marcello A, Pantano S. Customizably designed multibodies neutralize SARS-CoV-2 in a variant-insensitive manner. Front Immunol. 2023. doi: 10.3389/fimmu.2023.1226880

Milan Bonotto R, Mitrović A, Sosič I, Martínez-Orellana P, Dattola F, Gobec S, Kos J, Marcello A. Cathepsin inhibitors nitroxoline and its derivatives inhibit SARS-CoV-2 infection. Antiviral Res. 2023. doi: 10.1016/j.antiviral.2023.105655.

Ballotta L, Simonetti O, D’Agaro P, Segat L, Koncan R, Martinez-Orellana P, Dattola F, Orsini E, Marcello A, Dal Monego S, Licastro D, Misin A, Mohamed S, Sbisà E, Lucchini E, De Sabbata GM, Zaja F, Luzzati R. Case report: Long-lasting SARS-CoV-2 infection with post-COVID-19 condition in two patients with chronic lymphocytic leukemia: The emerging therapeutic role of casirivimab/imdevimab. Front Oncol. 2022. doi: 10.3389/fonc.2022.945060

Milan Bonotto R, Bonì F, Milani M, Chaves-Sanjuan A, Franze S, Selmin F, Felicetti T, Bolognesi M, Konstantinidou S, Poggianella M, Márquez CL, Dattola F, Zoppè M, Manfroni G, Mastrangelo E, Marcello A. Virucidal Activity of the Pyridobenzothiazolone Derivative HeE1-17Y against Enveloped RNA Viruses. Viruses. 2022, doi: 10.3390/v14061157

Rajasekharan S, Milan Bonotto R, Nascimento Alves L, Kazungu Y, Poggianella M, Martinez-Orellana P, Skoko N, Polez S, Marcello A. Inhibitors of Protein Glycosylation Are Active against the Coronavirus Severe Acute Respiratory Syndrome Coronavirus SARS-CoV-2. Viruses 2021, doi: 10.3390/v13050808

Milani M, Donalisio M, Milan Bonotto R, Schneider E, Arduino I, Boni F, Lembo D, Marcello A, Mastrangelo E. Combined in silico and in vitro approaches identified the antipsychotic drug lurasidone and the antiviral drug elbasvir as SARS-CoV2 and HCoV-OC43 inhibitors. Antiviral Res. 2021, doi: 10.1016/j.antiviral.2021.105055

Marcello A, Civra A, Milan Bonotto R, Nascimento Alves L, Rajasekharan S,Giacobone C,Caccia C, Cavalli R, Adami M, Brambilla P, Lembo D, Poli G, Leoni V. The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients. Redox Biology 2020, doi: 10.1016/j.redox.2020.101682

Salton F, Confalonieri P, Meduri G. U, Santus P, Harari S, Scala R, Lanini S, Vertui V, Oggionni T, Caminati A, Patruno V, Tamburrini M, Scartabellati A, Parati M, Villani M, Radovanovic D, Tomassetti S, Ravaglia C, Poletti V, Vianello A, Gaccione A. T, Guidelli L, Raccanelli R, Lucernoni P, Lacedonia D, Foschino Barbaro M. P, Centanni S, Mondoni M, Davì M, Fantin A, Cao X, Torelli L, Zucchetto A, Montico M, Casarin A, Romagnoli M, Gasparini S, Bonifazi M, D’Agaro P, Marcello A, Licastro D, Ruaro B, Volpe M. C, Umberger R, Confalonieri M. Prolonged Low-Dose Methylprednisolone in Patients With Severe COVID-19 Pneumonia. Open Forum Infect Dis. 2020, doi: 10.1093/ofid/ofaa421

Caracciolo I, Mora-Cardenas E, Aloise C, Carletti T, Segat L, Burali MS, Chiarvesio A, Totis V, Avšič-Županc T, Mastrangelo E, Manfroni G, D’Agaro P, Marcello A. Comprehensive response to Usutu virus following first isolation in blood donors in the Friuli Venezia Giulia region of Italy: Development of recombinant NS1-based serology and sensitivity to antiviral drugs. PLoS Negl Trop Dis. 2020, doi: 10.1371/journal.pntd.0008156

Cannalire R, Tarantino D, Piorkowski G, Carletti T, Massari S, Felicetti T, Barreca ML, Sabatini S, Tabarrini O, Marcello A, Milani M, Cecchetti V, Mastrangelo E, Manfroni G, Querat G. Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions. Antiviral Res. 2019, doi: 10.1016/j.antiviral.2019.03.004

Technologies

Vuerich R, Martinelli V, Vodret S, Bertani I, Carletti T, Zentilin L, Venturi V, Marcello A, Zacchigna S. A new laser device for ultra-rapid and sustainable aerosol sterilization. Environ Int. 2022, doi: 10.1016/j.envint.2022.107272

Maistriau M, Carletti T, Zakaria MK, Braga L, Faoro V, Vasileiadis V, Marcello A. A method for the detection of virus infectivity in single cells and real time: Towards an automated fluorescence neutralization test. Virus Res. 2017, doi: 10.1016/j.virusres.2017.05.004

Tagliabue G, Faoro V, Rizzo S, Sblattero D, Saccani A, Riccio G, Bellini T, Salina M, Buscaglia M, Marcello A. A label-free immunoassay for Flavivirus detection by the Reflective Phantom Interface technology. Biochem Biophys Res Commun. 2017, doi: 10.1016/j.bbrc.2017.05.025