Workshop “Genome editing to generate cellular and animal models of human diseases”

Cape Town, South Africa

13 – 16 September 2022

Scientific Organisers

Frank Brombacher (ICGEB Cape Town, South Africa)

Meeting Contact

ICGEB Cape Town Component
[email protected]

Deadline for receipt of applications:
1 July 2022 – Deadline extended

This workshop will provide insights on the opportunities and challenges offered by genome editing for the generation of cellular and animal models of human diseases and the development of innovative genetic therapies. The workshop is intended to provide a learning platform for researchers willing to implement the technology in their research and a forum for discussion on both scientific and regulatory challenges. Our vision is that in vivo and cellular (alternative) models have to be considered complementary, and not mutually exclusive, toward a better understanding of the genetic component of human diseases and the development of targeted molecular therapies. Thus, a comprehensive knowledge of the existing technology, followed by a critical cost-benefit assessment, will be critical for researchers to push their research beyond gene association studies. Participants from the ICGEB Member States will have facilitated access to this workshop, with the aim of fostering their access to the technology, understand their need and possibly establishing future services or capacity building actions.


Genome editing in animal models, Generation and use of genetically modified animal models, Cellular and animal models of human diseases, Development of innovative genetic therapies, CRISP, Cryopreservation, Mouse embryos and sperm models, In vitro fertilization models, Handling and performing procedures on mice and rats.


Applications will be selected based on academic merit which includes the quality of the motivation letter, CV and their research alignment to the meeting topics. Preferences will be given to technicians, PhD students, postdoctoral fellows, and junior faculty


Registration fees, accommodation, breakfast and lunch but not dinner will be covered for nationals of ICGEB Member States. Flight travel cost could partially be refunded but applicants need to organize and pay their flights in advance. VISA registration will be the responsibility of the applicants and not refunded but ICGEB will assist with support documentation. COVID-19 PCR testing to arrive in South Africa needs to be organized by the applicants but will be refunded. ICGEB will arrange and pay for PCR testing required for the home flights.

Applicants will be requested to upload one combined PDF file containing a Motivation Letter (2-page limit) and Curriculum vitae (3-page limit)

The Motivation Letter needs to list the experience of the candidate in animal research, handling and performing procedures on mice and rats, gene editing, CRISP, qPCR, cryopreservation, working with mouse embryos or sperm or IVF. If little experiences are listed, the Motivation Letter needs to state which technique will most benefit the applicant and home laboratory/animal facility, and whether research on mice or rats will be undertaken in future.

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Meeting Location

Rm S2.19, Wernher and Beit Building (South)
UCT Medical Campus
Anzio Road – Observatory 7925
Tel: +27-21-406 6335
Fax: +27-21-406 6060
[email protected]