Alessandro MANCON

Dirigente biologo, SC Microbiologia Clinica, Virologia e Diagnostica delle Bioemergenze

ASST Fatebenefratelli Sacco, Ospedale Universitario L. Sacco, Milano

The role of Clinical Microbiology and Virology in Arboviral and Other Infectious Diseases Management

Host: A. Marcello

Abstract
Infectious Diseases are a global Public Health concern, especially

because their are caused by pathogens that can spread and

affect a growing number of individuals; in addition, rapid genetic

evolution confers to aetiological agents the ability to escape the

hosts’ countermeasures, such as immune response, vaccines and

treatments.

Clinical Mcirbiology and Virology Laboratories have an essentials

role in Infetious Diseases management, implementing direct and

indirect assays to detect pathogens, their genomes or antigens, as

well as production of specific antibodies. Moreover, the increasing

availabilty of sequencing resources and capacities has paved the

way to large epidemiological investigations and mutations analyses

to detect diffusion of relevant mutations (i.e.: escape mutants, drugs

resistance).

Among all, Arboviruses are growing in importance, due to the more

frequent detection of authoctonous outbreaks in non-endemic

areas and larger epidemics in endemic ones. These occurrences join

with increasing diffusion of High Risk pathogens, such as Ebolavirus,

Rift Valley virus or Crimean-Congo virus, that claim for attention and

reliable and rapid responses.

International Seminar Programme

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