Our Projects

The ICGEB research groups participate in many calls for proposals on topics relevant to their fields of interest and are supported by a vast array of donors: from Governmental bodies to private companies, and charities. The major ongoing projects are shown here, divided under the Sustainable Development Goals that ICGEB strives to address. 

zero hunger

SUSGRAPE promotiong sustainable viticulture through ICT within ITA-SLO cross-border areas

Donor:
Regione Autonoma Friuli Venezia Giulia

Partners:
INTERREG Italia – Slovenia 2014-2020
ICGEB Bacteriology Lab

Duration: 2017-2020

Genetic improvement of rice for yield NUE, WUE, abiotic and biotic stress tolerance through RNA guided genome editing (CRISPR-Cas9/Cpf1)

Donor:
Indian Council of Agriculture Research (ICAR)

ICGEB Crop Improvement lab
Duration: 2017-2020

Re-designing Rice Crops for improvement grain micronutrient quality using CRISPR-Cas9/Cfp1 genome editing

Donor:
Indian Council of Agriculture Research (ICAR

ICGEB Nutritional Improvement of Crops lab

Duration: 2017-2020

good health

Cardiomiciti di cellule staminali per una cardiologia personalizzata – CardioStem

Donor
Regione Autonoma Friuli Venezia Giulia (L.R. 17/2014)

Partners
Azienda Sanitaria Universitaria Integrata Trieste ASUITS (Struttura complessa di Cardiologia)
ICGEB Molecular Medicine lab
Duration: 2019-2021

Bisimilars: Contribution to setting up the laboratory dedicated to research and quality certification of processes and biosimilar pharmaceuticals

Donor
Regione Autonoma Friuli Venezia Giulia (L.R. 17/2014)

ICGEB Biotechnology Development Unit
Duration: 2017-2020

TRAIN Big data and models of diseases: cross border platform of validated kits for biotech industry

Donor
Regione Autonoma Friuli Venezia Giulia

Partners
INTERREG Italia – Slovenia 2014-2020
ICGEB Biotechnology Development Unit
Duration: 2017-2020

Does lung tumour development suppress the presentation of neo-epitopes by type 1 denditric cells?

Donor
AIRC

ICGEB Cellular Immunology Lab, Trieste

Duration: 2018-2022

Charachterisation of the functions of the Human Papillomavirus E6 and E7 oncoproteins

Donor
AIRC

Partners
AIRC investigator Grant 2019
ICGEB Tumour Virology Lab

Duration: 20179-2024

Progetto per il consolidamento di una piattaform a di Medicina di Precisione in Cardiologia

Donor
Fondazione CRTrieste CARDIOGEN

Partners
Azienda Sanitaria Universitaria Integrata Trieste ASUITS (Struttura complessa di Cardiologia)
ICGEB Molecular Medicine Lab

Duration: 2017-2022

Development of exon specific U1 snRNA-based therapy for familiar Dysautonomia

Donor
Fondazione Telethon

ICGEB Human Molecular Genetics Lab

Duration: 2018-2021

MicroRNA per la terapia della fibrosi polmonare idiopatica

Donor:
Fondazione CRTrieste

Partners
University of Trieste
ICGEB Cardiovascular Biology Lab

Duration: 2017-2020

Full length RGNEF and/or“RGNEF leucine –rich domani”as a therapeutic target in ALS

Donor
Western Ontario University

ICGEB Molecular Pathology Lab
Duration: 2019-2022

Programming the failing heart to a regenerative state

Donor:
Foundation Leducq

Partners
Univ. Washington, Hubrecht Institute, Univ. Med. Centre Goettingen, Univ. Texas
ICGEB Molecular Medcine Lab
Duration: 2016-2020

Pre-clinical validation of FDA approved molecules able to rescue GAA pre-mRNAs plicing of c.-32-13T>G mutants as therapeutic agents for late- onset Pompe Disease

Donor:
Acid Maltase Deficiency Association – AMDA

Partners
Azienda Sanitaria Universitaria Integrata di Udine ASUIUD (University Hospital “Santa Maria della Misericordia”)
ICGEB Molecular Pathology Lab

Duration: 2019-2022

CureCN
ICGEB Mouse

Donor
Genethon

Molecular Genetics Lab

Duration: 2018-2022

Point-of-care per la rivelazione simultanea dei virus Zika, Dengue e Chikungunya

Donor
Regione Autonoma Friuli Venezia Giulia

Partners
Alifax Research, Laboratori Riuniti
ICGEB Molecular Virology Lab

Duration: 2018-2020

Epigenetic cross-talks and novel therapeutic strategies to prevent disease progression in ERG fusion positive prostate cancer

Donor
National Research Foundation – South Africa/SWISS Joint Research Cooperation Programme

Partners
Univ. Bern, Inst. Oncology Research, Bellinzona
ICGEB Cancer Genomics Lab
Duration: 2017-2020

Regulation of host splicing machinery by factors from mycobacterium tuberculosis and its impact on host innate defense mechanism

Donor
Wellcome Trust Alliance

ICGEB Cellular Immunology Lab
Duration: 2018-2022

A novel exon-specific U1 snRNA strategy to correct splicing in Familial Dysautonomia

Donor
National Eye Institute of the National Institutes of Health

Partner: Massachusetts General Hospital
ICGEB Human Molecular genetics Lab
Duration: 2018-2022

Biomolecular characterisation of Malaria parasite drug target dihydropteroate synthase

Donor
Department of Science and Technology (DST)

ICGEB Structural Parasitology Lab
Duration: 2018-2021

A Phase I, clinical trial to assess the safety and immunogenicity of P. falciparum vaccines

Donor: Biotechnology Industry Research Assistance Council (BIRAC)

ICGEB xx xx Lab
Duration: 2018-2020

Evolution and transmission of drug resistant tuberculosis in Agartala, Kohima and Imphal population

Donor: Department of Biotechnology (DBT)

Partner: Manipur Univ., Jawaharlal Nehru Inst. Medical Sciences, Naga Hospital Authority, Agartala Gov. Med. College

ICGEB Translational Health Lab

Duration: 2018-2021

Title: Translational research and clinical development of malaria vaccine candidates

Donor: Department of Biotechnology (DBT)

ICGEB xx Chauhan Lab

Duration: 2019-2022

Synthetic biology approach for producing artemisinin in edible plant and effective Malaria treatment by oral delivery of plant cells

Donor
Department of Biotechnology (DBT)

ICGEB Metabolic Engineering Lab

Duration: 2018-2021


Functional delineation of viral encoded RNAi suppressor on plant miRNA pathways

Donor
Department of Biotechnology (DBT)

ICGEB Transcriptional Regulation Lab

Duration: 2018-2021

Genomics-driven dissection of susceptibility geographical focus on NER

Donor
Department of Biotechnology (DBT)

Partner:
National Inst. Biomed. Genomics, Foundation Neglected Disease Res., Mizoram University, Dpt. Health & Family Welfare
ICGEB Cellular Immunology Lab

Duration: 2018-2021

Development of a chikungunya candidate vaccine in vesicular stomatitis virus (VSV) gene delivery platform

Donor
Department of Biotechnology (DBT)

ICGEB Vector Borne Diseases Lab
Duration: 2019-2022


Comprehensive omics studies to understand the biology of drug resistant Mycobacterium tuberculosis clinical isolates from Arunachal Pradesh

Donor
Department of Biotechnology (DBT)

ICGEB Parasitic Cell Biology Lab

Duration: 2019-2022

Human B Cell responses and receptor repertoire in dengue patients from India

Donor
Department of Biotechnology (DBT)

ICGEB EMORY-ICGEB Vaccine Program

Duration: 2019-2021

Hit to lead development of potent anti-parasitic natural product scaffolds

Donor
Department of Science and Technology (DST)

ICGEB Structural Parasitology Lab

Duration: 2019-2023

Membrane biogenesis in Apicomplexa parasites: trafficking and recycling lipid sources for membrane remodelling as drug targets against malaria and toxoplasmosis

Donor
Indo-French Centre for Promotion of Advanced Research

ICGEB Parasite Cell Lab

Duration: 2019-2023

Translational Research Consortia for establishing platform technologies to support prophylactic and therapeutic strategies for Dengue discovey to proof of concept

Donor
Biotechnology Industry Research Assistance Council (BIRAC)

ICGEB EMORY-ICGEB Vaccine Program

Duration: 2019-2023


Translational research consortia TRC for Chikungunya virus

Donor
Biotechnology Industry Research Assistance Council (BIRAC)

ICGEB Vectorn Borne Diseases Lab

Duration: 2019-2024

Structure determination and targeting of ubiquitously expressed membrane integrated form of chloride intracellular channels (CLICs) for discovery of small molecular anti-cancer therapeutics

Donor
Department of Biotechnology (DBT)

ICGEB Membrane Protein Biology Lab

Duration: 2019-2023

Targeting drug resistance in tuberculosis and malaria

Donor
Department of Biotechnology (DBT)

ICGEB Structural Immunology Lab

Duration: 2019-2023


Effect of Repeated Chemotherapy with Praziquantel on resistance to reinfection and protection against pathology during murine schistosomiasis: Mechanistic studies

Donor
MERCK Global Health Institute

ICGEB Cytokines & Disease Lab

Duration: 2017-2020

Bio molecular characterization of a malaria parasite drug substrate dihydropteroate synthase (DHPS)

Donor
Department of Science and Technology (DST)

ICGEB Structural Parasitology Lab

Duration: 2019-2023


quality education

ComUnicaRe per crescere In SAlute-Curiosa

Donor
Regione Autonoma Friuli Venezia Giulia

ICGEB Cardiovascular Biology Lab

Duration: 2019-2022

affordable energy

Development of paenibacillus polymyxa as a platform for production of branched chain alcohols

Donor
Department of Biotechnology (DBT)

ICGEB Microbial EngineeringI Lab

Duration: 2019-2022

Chloroplast metabolic engineering of Artemisia annua for enhancing artemisinin biosynthesis

Donor
Department of Biotechnology (DBT)

ICGEB Microbial Engineering Lab
Duration: 2018-2021

Reducing industrial waste from sugar cane processing in India

Donor
Department of Biotechnology (DBT)

ICGEB MicrobialEngineering Lab

Duration: 2018-2021

Demonstration of algal chassis for the photo autotrophic production of isoprenoids

Donor
Department of Biotechnology (DBT)

ICGEB Omics of Algae Lab

Duration: 2018-2021

Indian Marine cyanobacterial host for production of drop-in fuels

Donor
Department of Biotechnology (DBT)

ICGEB Microbial Engineering Lab

Duration: 2019-2022

Carbonaceous gas to fuel by genetically engineered organisms

Donor
TATA STEEL LIMITED

ICGEB Microbial Engineering Lab

Duration: 2019-2022

industry innovation

LaserNET-Strengthening laser therapy as treatment of oral mucositis, stomatitis, dermatitis

Donor
Regione Autonoma Friuli Venezia Giulia

ICGEB Cardiovascular Biology Lab
Duration: 2018-2020


STARBIOS2 Structural Transformation to Attain Responsible BIOSciences

Donor:
EU Horizon 2020

Partners
12 partners in Brazil, Bulgaria, Denmark, Germany, Italy, Poland, Slovenia, South Africa, Sweden, UK and USA
ICGEB Cancer Genomics Lab
Duration: 2016-2019

Assist the goverment of Panama to create a legal framework that will implement the provisions of the Cartagena Protocol on Biosafety

UNEP Latin America and the Caribbean Office

ICGEB Regulatory Science Group

Duration: 2019-2020

Assist the goverment of Panama to create a legal framework that will implement the provisions of the Cartagena Protocol on Biosafety

Donor
Bill & Melinda Gates Foundation

ICGEB Regulatory Science Group

Duration: 2012-2020

partnership for the goals