The ICGEB research groups participate in many calls for proposals on topics relevant to their fields of interest and are supported by a vast array of donors: from Governmental bodies to private companies, and charities. The major ongoing projects are shown here, divided under the Sustainable Development Goals that ICGEB strives to address.
zero hunger
Editing rice genes through CRISPR/Cas9 technology for enhanced and durable blast resistance in rice
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Crop Improvement Group New Delhi, M. K. Reddy
Duration: 2020-2022
Donor
Indian Council of Agricultural Research (ICAR)
ICGEB Crop Improvement Group New Delhi, M. K. Reddy
Duration: 2018-2021
Re-designing rice crops for improved grain micronutrient quality using CRISPR-Cas9/Cpf1 genome editing
Donor
Indian Council of Medical Research (ICMR)
ICGEB Nutritional Improvement of Crops Group New Delhi, T. Kaul
Duration: 2019-2021
Develop bacterial biofertilizers for Coffea canephora (C.robusta)
Donor:
MAECI
ICGEB Bacteriology Lab Trieste, V. Venturi
Duration: 2021-2023
good health
Donor
European Regional Development Fund and Interreg V-A Italy-Austria 2014-2020
Partners
Eurac Research, Medical University of Innsbruck, Carinthia University of Applied Sciences
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2020-2022
Cardiomiciti di cellule staminali per una cardiologia personalizzata – CardioStem
Donor
Regione Autonoma Friuli Venezia Giulia (L.R. 17/2014)
Partners
Azienda Sanitaria Universitaria Integrata Trieste ASUITS (Struttura complessa di Cardiologia)
ICGEB Molecular Medicine Lab Trieste, M. Giacca
Duration: 2019-2021
The rolE of the matRix in cAncer protection: leSsons from the hEart and novel therapeutic opportunities – ERASE
Donor
AIRC Investigator Grant 2020
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2020-2026
Donor
European Regional Development Fund and Interreg V-A Italy – Slovenia 2014-2020
Partners
Valdoltra Orthopedic Hospital (Ankaran, Slovenia), University of Ljubljiana, Faculty of Chemistry and Chemical Technology, Dr. Paladin, Jafral
ICGEB Molecular Virology Lab Trieste, A. Marcello
Duration: 2019-2021
Does lung tumour development suppress the presentation of neo-epitopes by type 1 denditric cells?
Donor
AIRC Investigator Grant 2018
ICGEB Cellular Immunology Lab Trieste, F. Benvenuti
Duration: 2019-2024
Charachterisation of the functions of the Human Papillomavirus E6 and E7 oncoproteins
Donor
AIRC investigator Grant 2019
ICGEB Tumour Virology Lab Trieste, L. Banks
Duration: 2020-2025
CARDIORiGen
Donor
Fondazione CRTrieste CARDIOGEN
Partners
Azienda Sanitaria Universitaria Integrata Trieste ASUITS (Struttura complessa di Cardiologia)
ICGEB Molecular Medicine Lab Trieste, M. Giacca
Duration: 2019-2022
cGAS-STING driven activation of type-I interferone in Wiskott-Aldrich syndrome
Donor
Fondazione Telethon
ICGEB Cellular Immunology Lab Trieste, F. Benvenuti
Duration: 2021-2024
Liver-directed promotierless gene targeting without the use of nucleases as a potential therapy for Fabry disease
Donor
Fondazione Telethon
ICGEB Mouse Molecular Genetics Lab Trieste, A. Muro
Duration: 2021-2024
Full-length RGNEF and/or “RGNEF leucine–rich domain” as a therapeutic target in ALS
Donor
Western Ontario University
ICGEB Molecular Pathology Lab Trieste, E. Buratti
Duration: 2019-2022
Structured-based approach to develop a novel mechanism-of-action antimalarial with multistage activity
Donor
The Broad Institute
ICGEB Emory Vaccine Program New Delhi, A. Chandele
Duration: 2020-2022
Pre-clinical validation of FDA-approved molecules able to rescue GAA pre-mRNAs plicing of c.-32-13T>G mutants as therapeutic agents for late- onset Pompe Disease
Donor
Acid Maltase Deficiency Association – AMDA
Partners
Azienda Sanitaria Universitaria Integrata di Udine ASUIUD (University Hospital “Santa Maria della Misericordia”)
ICGEB Molecular Pathology Lab Trieste, E. Buratti
Duration: 2019-2022
Development of dipeptide based targeted nanoformulation for breast cancer
Donor
Genethon
Mouse Molecular Genetics Lab Trieste, A. Muro
Duration: 2020-2022
Evoluzione di SARS-CoV-2 e analisi della risposta cellulare all’infezione nell’ambito del Sistema ARGO
Donor
AREA Science Park
ICGEB Molecular Virology Lab Trieste, A. Marcello
Duration: 2020-2022
Epigenetic cross-talks and novel therapeutic strategies to prevent disease progression in ERG fusion positive prostate cancer
Donor
National Research Foundation – South Africa/SWISS Joint Research Cooperation Programme
Partners
Univ. Bern, Inst. Oncology Research, Bellinzona
ICGEB Cancer Genomics Lab Cape Town, L. Zerbini
Duration: 2017-2020
Regulation of host splicing machinery by factors from mycobacterium tuberculosis and its impact on host innate defense mechanism
Donor
Wellcome Trust Alliance
ICGEB Cellular Immunology Lab New Delhi, D. Kumar
Duration: 2018-2022
A novel exon-specific U1 snRNA strategy to correct splicing in Familial Dysautonomia
Donor
National Eye Institute of the National Institutes of Health
Partner
Massachusetts General Hospital
ICGEB Human Molecular Genetics Lab Trieste, F. Pagani
Duration: 2018-2022
Biomolecular characterisation of Malaria parasite drug target dihydropteroate synthase
Donor
Department of Science and Technology (DST), Government of India
ICGEB Structural Parasitology Lab New Delhi, A. Sharma
Duration: 2018-2021
A Phase I, clinical trial to assess the safety and immunogenicity of P. falciparum vaccines
Donor
Biotechnology Industry Research Assistance Council (BIRAC)
Partner
ICGEB New Delhi, V.S. Chauhan
Duration: 2018-2020
Evolution and transmission of drug resistant tuberculosis in Agartala, Kohima and Imphal population
Donor
Department of Biotechnology (DBT), Government of India
Partners
Manipur Univ., Jawaharlal Nehru Inst. Medical Sciences, Naga Hospital Authority, Agartala Gov. Med. College
ICGEB Translational Health Lab New Delhi, R. Nanda
Duration: 2018-2021
Translational research and clinical development of malaria vaccine candidates
Donor
Department of Biotechnology (DBT), Government of India
ICGEB New Delhi, V.S. Chauhan
Duration: 2019-2022
Synthetic biology approach for producing artemisinin in edible plant and effective Malaria treatment by oral delivery of plant cells
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Metabolic Engineering Lab New Delhi, S. Kumar
Duration: 2018-2021
Functional delineation of viral encoded RNAi suppressor on plant miRNA pathways
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Transcription Regulation Group New Delhi, N. Sarovar Bhavesh
Duration: 2018-2021
Genomics-driven dissection of susceptibility geographical focus on NER
Donor
Department of Biotechnology (DBT), Government of India
Partners
National Inst. Biomed. Genomics, Foundation Neglected Disease Res., Mizoram University, Dpt. Health & Family Welfare
ICGEB Cellular Immunology Lab New Delhi, D. Kumar
Duration: 2018-2021
Development of a chikungunya candidate vaccine in vesicular stomatitis virus (VSV) gene delivery platform
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Vector-Borne Diseases Lab New Delhi, S. Sunil
Duration: 2019-2022
Comprehensive omics studies to understand the biology of drug resistant Mycobacterium tuberculosis clinical isolates from Arunachal Pradesh
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Parasite Cell Biology Lab New Delhi, A. Mohmmed
Duration: 2019-2022
Human B Cell responses and receptor repertoire in dengue patients from India
Donor
Department of Biotechnology (DBT), Government of India
ICGEB EMORY-ICGEB Vaccine Program, A. Chandele
Duration: 2019-2021
Hit to lead development of potent anti-parasitic natural product scaffolds
Donor
Department of Science and Technology (DST), Government of India
ICGEB Structural Parasitology Lab New Delhi, A. Sharma
Duration: 2019-2022
Membrane biogenesis in Apicomplexa parasites: trafficking and recycling lipid sources for membrane remodelling as drug targets against malaria and toxoplasmosis
Donor
Indo-French Centre for Promotion of Advanced Research
ICGEB Parasite Cell Biology Lab New Delhi, A. Mohmmed
Duration: 2019-2022
Translational Research Consortia for establishing platform technologies to support prophylactic and therapeutic strategies for Dengue discovey to proof of concept
Donor
Biotechnology Industry Research Assistance Council (BIRAC)
ICGEB EMORY Vaccine Program, A. Chandele
Duration: 2019-2023
Translational research consortia TRC for Chikungunya virus
Donor
Biotechnology Industry Research Assistance Council (BIRAC)
ICGEB Vector-Borne Diseases Lab New Delhi, S. Sunil
Duration: 2019-2023
Structure determination and targeting of ubiquitously expressed membrane integrated form of chloride intracellular channels (CLICs) for discovery of small molecular anti-cancer therapeutics
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Membrane Protein Biology Lab New Delhi, A. Arulandu
Duration: 2019-2022
Targeting drug resistance in tuberculosis and malaria
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Structural Immunology Lab New Delhi, D. Salunke
Duration: 2019-2022
EMBO symposium titled Mycobacterial heterogeneity and host tissue tropism
Donor
EMBO
ICGEB Cellular Immunology Lab New Delhi, D. Kumar
Duration: 2020
Design, validation and development of novel peptidomimetic
Donor
Department of Science and Technology (DST), Government of India
ICGEB Membrane Protein Biology Lab New Delhi, A. Arulandu
Duration: 2020-2022
LaserNET-Strengthening laser therapy as treatment of oral mucositis, stomatitis, dermatitis
Donor
Regione Autonoma Friuli Venezia Giulia, L.R. 19/2000
Partners
Clinical Centre of Serbia, Inst. Oncology & Radioth. of Serbia, Univ. Children Hosp. of Serbia, Univ. Trieste, Pediatric Hosp. Burlo Garofolo, Trieste
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2018-2021
In vivo models to study the role of genetic lesions and microenvironmental signals in driving CLL cell proliferation
Donor
AIRC Investigator Grant 2020
ICGEB Molecular Hematology Lab Trieste, D. Efremov
Duration: 2021-2025
Metastatic disease: the key to unmet need in oncology – 5 per mille 2019
Donor
AIRC Investigator Grant 2020
ICGEB Cancer Cell Signalling Trieste, G. Del Sal
Duration: 2019-2026
Defining the role of hnRNP proteins in enhancing TDP-43 pathology – PathensTDP
Donor
AriSLA
ICGEB Molecular Pathology Lab Trieste, E. Buratti
Duration: 2019-2022
Identificazione di Coronavirus SARS-CoV-2 e definizione della risposta cellulare innata ed adattiva
Donor
Assicurazioni GENERALI
ICGEB Molecular Virology Lab Trieste, A. Marcello
Duration: 2020-2022
COVID-19: Establishing rapid laboratory diagnostics programs in LMICs
Donor
Bill&Melinda Gates Foundation
Partners
New England Biolabs, Chantal Biya Int. Reference Centre in Cameroon, Ethiopian Biotech Institute (EBTi), Kenya Medical Research Institute – KEMRI, College of Medical Sciences, University of Maiduguri, Department of Medical Laboratory Science – Nigeria
ICGEB Molecular Virology Lab Trieste, A. Marcello
Duration: 2020-2021
Development of dipeptide based targeted nanoformulation for breast cancer
Donor
Biotechnology Industry Research Assistance Council (BIRAC)
ICGEB New Delhi, V. S. Chauhan
Duration: 2020-2022
Renovation and daily running of BL3 Laboratory
Donor
Bene centia Stiftung
ICGEB Molecular Virology Lab Trieste, A. Marcello
Duration: 2020-2022
Donor
Regione Autonoma Friuli Venezia Giulia, L.R. 45/2017
ICGEB Biotechnology Development Unit Trieste, N. Skoko
Duration: 2017-2021
ComUnicaRe per crescere In SAlute-Curiosa
Donor
Regione Autonoma Friuli Venezia Giulia, L.R. 17/2014
Partner
University of Trieste (Dipartimento di Scienze Mediche e Chirurgiche e della Salute)
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2019-2022
Exploiting diversity oriented chemical synthesis for combating chronic parasitic infection
Donor
National Institutes of Health
ICGEB Structural Parasitology Lab New Delhi, A. Sharma
Duration: 2020-2023
Professional Development Programme
Donor
National Research Foundation
South Africa/SWISS Joint Research Cooperation Programme
ICGEB Cancer Genomics Lab Cape Town, L. Zerbini
Duration: 2020-2022
TBFVnet: surveillance and research on tick-borne aviviruses (TBFV)
Donor
Norway Grants Fund
Partners
Veterinary Res. Institute – Czech Republic, Chumakov Federal Scientific Centre – Russia, Biomedical Research Centre Slovak Academy of Sciences, Norwegian Institute of Public Health – Norway, Umea University – Sweden
ICGEB Molecular Virology Lab Trieste, A. Marcello
Duration: 2020-2024
INCardio INTERREG Italia-Austria
Donor
Provincia Autonoma Bolzano Alto Adige INTERREG ITALIA-AUSTRIA 2014-2020
Partners
EURAC, MUIC, CUAS
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2020-2021
PREFER
Donor
POR FESR 2014-2020
Partners
Vivabiocell, Zeta Research, Università degli Studi di Trieste
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2018-2022
Dengue Vaccine Programme
Donor
SunPharma International
ICGEB Translational Health Group New Delhi, N. Khanna
Duration:2016-2021
Regenerative strategies for heart disease via targeting the long noncoding transcriptome – SINERGIA
Donor
Swiss National Fund
Partner
University of Lausanne Medical School
ICGEB Molecular Medicine Lab Trieste, M. Giacca
Duration: 2017-2021
Development of exon specific U1 snRNA-based therapy for familiar Dysautonomia
Donor
Fondazione Telethon
ICGEB Human Molecular Genetics Lab Trieste, F. Pagani
Duration: 2018-2021
quality education
ComUnicaRe per crescere In SAlute-Curiosa
Donor
Regione Autonoma Friuli Venezia Giulia, L.R. 17/2014
Partner
University of Trieste (Dipartimento di Scienze Mediche e Chirurgiche e della Salute)
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2019-2022
LaserNET-Strengthening laser therapy as treatment of oral mucositis, stomatitis, dermatitis
Donor
Regione Autonoma Friuli Venezia Giulia, L.R. 19/2000
Partners
Clinical Centre of Serbia, Inst. Oncology & Radioth. of Serbia, Univ. Children Hosp. of Serbia, Univ. Trieste, Pediatric Hosp. Burlo Garofolo, Trieste
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2018-2021
Organizing an International summit on women in STEM
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Structural Immunology Lab New Delhi, D. Salunke
Duration: 2020
affordable energy
Development of Paenibacillus polymyxa as a platform for production of branched chain alcohols
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Microbial Engineering Lab New Delhi, S. Yazdani
Duration: 2019-2022
Chloroplast metabolic engineering of Artemisia annua for enhancing artemisinin biosynthesis
Donor
Department of Biotechnology (DBT), Government of India
Partner
Jamia Hamdard University
ICGEB Metabolic Engineering Lab New Delhi, S. Kumar
Duration: 2018-2021
Reducing industrial waste from sugar cane processing in India
Donor
Department of Biotechnology (DBT), Government of India
Partner
University of York (UK), University of Leon (Spain), Jesmond Engineering Ltd (UK)
ICGEB Microbial Engineering Lab New Delhi, S. Yazdani
Duration: 2018-2021
Demonstration of algal chassis for the photo autotrophic production of isoprenoids
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Omics of Algae Lab New Delhi, P. Jutur
Duration: 2019-2022
Indian Marine cyanobacterial host for production of drop-in fuels
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Microbial Engineering Lab New Delhi, S. Yazdani
Duration: 2019-2022
Genetic engineering of microalgae for producing alkanes for further applications
Donor
Department of Biotechnology (DBT), Government of India
ICGEB Metabolic Engineering Lab New Delhi, S. Kumar Rhode and N. Gaur
Duration: 2020-2022
Psilocybin producing S. cerevisiae strain with the yield of 1000 mg/L in laboratory scale fermenter (500ml)
Donor
Nirvana Life Science Inc.
ICGEB Yeast Biofuel Lab New Delhi, N. Gaur
Duration: 2020-2021
ComUnicaRe per crescere In SAlute-Curiosa
Donor
Regione Autonoma Friuli Venezia Giulia, L.R. 17/2014
Partner
University of Trieste (Dipartimento di Scienze Mediche e Chirurgiche e della Salute)
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2019-2022
Carbonaceous gas to fuel by genetically engineered organisms
Donor
TATA STEEL LIMITED
ICGEB Microbial Engineering Lab New Delhi, S. Yazdani
Duration: 2019-2022
industry innovation
partnership for the goals
CUTTiNG 2020
Donor
Ministero dello Sviluppo Economico, Governo Italiano
ICGEB Fundraising TT & Innovation, M. Viviani
Duration: 2020-2023