The ICGEB research groups participate in many calls for proposals on topics relevant to their fields of interest and are supported by a vast array of donors: from Governmental bodies to private companies, and charities. The major ongoing projects are shown here, divided under the Sustainable Development Goals that ICGEB strives to address in particular through its Strategic Framework, while cross-cutting actions also cover SDG5, SDG12, SDG13 and SDG15.
zero hunger
Donor
Department of Biotechnology (DBT), Government of India
Editing rice genes through CRISPR/Cas9 technology for enhanced and durable blast resistance in rice
ICGEB Crop Improvement Group New Delhi, M. K. Reddy
Duration: 2020-2022
Donor
Indian Council of Agricultural Research (ICAR)
ICGEB Crop Improvement Group New Delhi, M. K. Reddy
Duration: 2018-2021
Donor
Indian Council of Medical Research (ICMR)
Re-designing rice crops for improved grain micronutrient quality using CRISPR-Cas9/Cpf1 genome editing
ICGEB Nutritional Improvement of Crops Group New Delhi, T. Kaul
Duration: 2019-2021
Donor
Ministry of Foreign Affairs and International Cooperation (MAECI), Government of Italy
Developing bacterial biofertilizers for Coffea canephora (C. robusta)
ICGEB Bacteriology Lab Trieste, V. Venturi
Duration: 2021-2023
Donor
Standards and Trade Development Facility
Enhancing trade through regulatory harmonisation and biopesticide-based residue mitigation in the SADC region
Cape Town, D. Ndolo
Duration: 2021-2024
Donor
South Africa National Research Foundation
Biocontrol options for fall armyworm control in Southern Africa
Cape Town, D. Ndolo
Duration: 2019 – 2022
good health
Donor
Acid Maltase Deficiency Association – AMDA
Pre-clinical validation of FDA-approved molecules able to rescue GAA pre-mRNAs plicing of c.-32-13T>G mutants as therapeutic agents for late- onset Pompe Disease
Partners
Azienda Sanitaria Universitaria Integrata di Udine ASUIUD (University Hospital “Santa Maria della Misericordia”)
ICGEB Molecular Pathology Lab Trieste, E. Buratti
Duration: 2019-2022
Donor
AIRC Investigator Grant 2020
Metastatic disease: the key to unmet need in oncology – 5 per mille 2019
ICGEB Cancer Cell Signalling Trieste, G. Del Sal
Duration: 2019-2026
Donor
AIRC Investigator Grant 2020
The rolE of the matRix in cAncer protection: leSsons from the hEart and novel therapeutic opportunities – ERASE
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2020-2026
Donor
AIRC Investigator Grant 2020
In vivo models to study the role of genetic lesions and microenvironmental signals in driving CLL cell proliferation
ICGEB Molecular Hematology Lab Trieste, D. Efremov
Duration: 2021-2025
Donor
AIRC Investigator Grant 2019
Characterisation of the functions of the Human Papillomavirus E6 and E7 oncoproteins
ICGEB Tumour Virology Lab Trieste, L. Banks
Duration: 2020-2025
Donor
AIRC Investigator Grant 2018
Does lung tumour development suppress the presentation of neo-epitopes by type 1 denditric cells?
ICGEB Cellular Immunology Lab Trieste, F. Benvenuti
Duration: 2019-2024
Donor
AriSLA
Defining the role of hnRNP proteins in enhancing TDP-43 pathology – PathensTDP
ICGEB Molecular Pathology Lab Trieste, E. Buratti
Duration: 2019-2022
Donor
Assicurazioni GENERALI
Identificazione di Coronavirus SARS-CoV-2 e definizione della risposta cellulare innata ed adattiva
ICGEB Molecular Virology Lab Trieste, A. Marcello
Duration: 2020-2022
Donor
Beneficentia Stiftung
Renovation and daily running of BL3 Laboratory
ICGEB Molecular Virology Lab Trieste, A. Marcello
Duration: 2020-2022
Donor
Bill&Melinda Gates Foundation
COVID-19: Establishing rapid laboratory diagnostics programs in LMICs
Partners
New England Biolabs, Chantal Biya Int. Reference Centre in Cameroon, Ethiopian Biotech Institute (EBTi), Kenya Medical Research Institute – KEMRI, College of Medical Sciences, University of Maiduguri, Department of Medical Laboratory Science – Nigeria
ICGEB Molecular Virology Lab Trieste, A. Marcello
Duration: 2020-2021
Donor
Bill&Melinda Gates Foundation
COVID-19: Community Access Diagnostics laboratory networks
Partners
New England Biolabs, LabGene, IRSS Bobo-Dioulasso (Burkina Faso), Chantal Biya Int. Reference Centre, Ethiopian Biotech Institute (EBTi), Pasteur Institut Abidjan, Kenya Medical Research Institute – KEMRI, University of Maiduguri Teaching Hospital, Institute for Research, Epidemiological Surveillance and Training (IRESSEF), National Institute for Tropical Disease (Sudan), National Microbiology Reference Laboratory – NMRL (Burkina Faso)
Duration: 2021-2023
Donor
Biotechnology Industry Research Assistance Council (BIRAC)
Translational research consortia TRC for Chikungunya virus
ICGEB Vector-Borne Diseases Lab New Delhi, S. Sunil
Duration: 2019-2023
Donor
Biotechnology Industry Research Assistance Council (BIRAC)
Translational Research Consortia for establishing platform technologies to support prophylactic and therapeutic strategies for Dengue discovey to proof of concept
ICGEB EMORY Vaccine Program, A. Chandele
Duration: 2019-2023
Donor
Biotechnology Industry Research Assistance Council (BIRAC)
Development of dipeptide based targeted nanoformulation for breast cancer
ICGEB New Delhi, V. S. Chauhan
Duration: 2020-2022
Donor
Broad Institute
Structured-based approach to develop a novel mechanism-of-action antimalarial with multistage activity
ICGEB Emory Vaccine Program New Delhi, A. Chandele
Duration: 2020-2022
Donor
Department of Biotechnology (DBT), Government of India
Human B Cell responses and receptor repertoire in dengue patients from India
ICGEB EMORY-ICGEB Vaccine Program, A. Chandele
Duration: 2019-2021
Donor
Department of Biotechnology (DBT), Government of India
Translational research and clinical development of malaria vaccine candidates
ICGEB New Delhi, V.S. Chauhan
Duration: 2019-2022
Donor
Department of Biotechnology (DBT), Government of India
Structure determination and targeting of ubiquitously expressed membrane integrated form of chloride intracellular channels (CLICs) for discovery of small molecular anti-cancer therapeutics
ICGEB Membrane Protein Biology Lab New Delhi, A. Arulandu
Duration: 2019-2022
Donor
Department of Biotechnology (DBT), Government of India
Gene editing of key plasmodium transporters and lipid metabolism enzymes to decipher parasite drug resistance mechanisms
ICGEB Malaria Biology Lab New Delhi, P. Malhotra
Duration: 2018-2022
Donor
Department of Biotechnology (DBT), Government of India
Targeting drug resistance in tuberculosis and malaria
ICGEB Structural Immunology Lab New Delhi, D. Salunke
Duration: 2019-2022
Donor
Department of Biotechnology (DBT), Government of India
Comprehensive omics studies to understand the biology of drug resistant Mycobacterium tuberculosis clinical isolates from Arunachal Pradesh
ICGEB Parasite Cell Biology Lab New Delhi, A. Mohmmed
Duration: 2019-2022
Donor
Department of Biotechnology (DBT), Government of India
Genomics-driven dissection of susceptibility geographical focus on NER
Partners
National Inst. Biomed. Genomics, Foundation Neglected Disease Res., Mizoram University, Dpt. Health & Family Welfare
ICGEB Cellular Immunology Lab New Delhi, D. Kumar
Duration: 2018-2021
Donor
Department of Biotechnology (DBT), Government of India
Development of a chikungunya candidate vaccine in vesicular stomatitis virus (VSV) gene delivery platform
ICGEB Vector-Borne Diseases Lab New Delhi, S. Sunil
Duration: 2019-2022
Donor
Department of Biotechnology (DBT), Government of India
Synthetic biology approach for producing artemisinin in edible plant and effective Malaria treatment by oral delivery of plant cells
ICGEB Metabolic Engineering Lab New Delhi, S. Kumar
Duration: 2018-2021
Donor
Department of Biotechnology (DBT), Government of India
Evolution and transmission of drug resistant tuberculosis in Agartala, Kohima and Imphal population
Partners
Manipur Univ., Jawaharlal Nehru Inst. Medical Sciences, Naga Hospital Authority, Agartala Gov. Med. College
ICGEB Translational Health Lab New Delhi, R. Nanda
Duration: 2018-2021
Donor
Department of Biotechnology (DBT), Government of India
Functional delineation of viral encoded RNAi suppressor on plant miRNA pathways
ICGEB Transcription Regulation Group New Delhi, N. Sarovar Bhavesh
Duration: 2018-2021
Donor
Department of Biotechnology (DBT), Government of India
Developing double herbicide tolerant pigeonpen for improved weed management employing two pronged approach: haplotype mining in native germplasm and CRISPR/Cas9 memdiated genome editing tool
ICGEB Nutritional Improvement of Crops Lab New Delhi, T. Kaul
Duration: 2021-2024
Donor
Department of Science and Technology (DST), Government of India
Design, validation and development of novel peptidomimetic
ICGEB Membrane Protein Biology Lab New Delhi, A. Arulandu
Duration: 2020-2022
Donor
Department of Science and Technology (DST), Government of India
Hit to lead development of potent anti-parasitic natural product scaffolds
ICGEB Structural Parasitology Lab New Delhi, A. Sharma
Duration: 2019-2022
Donor
Department of Science and Technology (DST), Government of India
Biomolecular characterisation of Malaria parasite drug target dihydropteroate synthase
ICGEB Structural Parasitology Lab New Delhi, A. Sharma
Duration: 2018-2021
Donor
European Regional Development Fund and Interreg V-A Italy-Austria 2014-2020
Partners
Eurac Research, Medical University of Innsbruck, Carinthia University of Applied Sciences
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2020-2022
Donor
European Regional Development Fund and Interreg V-A Italy – Slovenia 2014-2020
Partners
Valdoltra Orthopedic Hospital (Ankaran, Slovenia), University of Ljubljiana, Faculty of Chemistry and Chemical Technology, Dr. Paladin, Jafral
ICGEB Molecular Virology Lab Trieste, A. Marcello
Duration: 2019-2021
Donor
Fondazione CRTrieste CARDIOGEN
CARDIORiGen
Partners
Azienda Sanitaria Universitaria Integrata Trieste ASUITS (Struttura complessa di Cardiologia)
ICGEB Molecular Medicine Lab Trieste, M. Giacca
Duration: 2019-2022
Donor
Fondazione Telethon
cGAS-STING driven activation of type-I interferone in Wiskott-Aldrich syndrome
ICGEB Cellular Immunology Lab Trieste, F. Benvenuti
Duration: 2021-2024
Donor
Fondazione Telethon
Liver-directed promotierless gene targeting without the use of nucleases as a potential therapy for Fabry disease
ICGEB Mouse Molecular Genetics Lab Trieste, A. Muro
Duration: 2021-2024
Donor
Genethon
Adeno-Associated Virus Vector-Mediated Liver Gene Therapy for Crigler-Najjar Syndrome WP5
Mouse Molecular Genetics Lab Trieste, A. Muro
Duration: 2018-2022
Donor
Genethon
Adeno-Associated Virus Vector-Mediated Liver Gene Therapy for Crigler-Najjar Syndrome – CureCN
Mouse Molecular Genetics Lab Trieste, A. Muro
Duration: 2018-2022
Donor
Indian Council of Medical Research
Human Monoclonals to COVID-19
ICGEB-EMORY Vaccine Program New Delhi, A. Chandele
Duration: 2020-2021
Donor
Indo-French Centre for Promotion of Advanced Research
Membrane biogenesis in Apicomplexa parasites: trafficking and recycling lipid sources for membrane remodelling as drug targets against malaria and toxoplasmosis
ICGEB Parasite Cell Biology Lab New Delhi, A. Mohmmed
Duration: 2019-2022
Donor
Ministry of Health, Government of Italy
VLA-4 IN CLL (RF Ministero Salute)
Partner
ICGEB Molecular Hematology Lab Trieste, D. Efremov
Duration: 2018-2021
Donor
National Eye Institute of the National Institutes of Health
A novel exon-specific U1 snRNA strategy to correct splicing in Familial Dysautonomia
Partner
Massachusetts General Hospital
ICGEB Human Molecular Genetics Lab Trieste, F. Pagani
Duration: 2018-2022
Donor
National Institutes of Health
Exploiting diversity oriented chemical synthesis for combating chronic parasitic infection
ICGEB Structural Parasitology Lab New Delhi, A. Sharma
Duration: 2020-2023
Donor
National Research Foundation
South Africa
Epigenetic cross-talks and novel therapuetic strategies to prevent disease progression in ERG fusion positive prostrate cancer
ICGEB Cancer Genomics Lab Cape Town, L. Zerbini
Duration: 2017-2021
Donor
National Research Foundation
South Africa/SWISS Joint Research Cooperation Programme
Professional Development Programme
ICGEB Cancer Genomics Lab Cape Town, L. Zerbini
Duration: 2020-2022
Donor
Norway Grants Fund
TBFVnet: surveillance and research on tick-borne aviviruses (TBFV)
Partners
Veterinary Res. Institute – Czech Republic, Chumakov Federal Scientific Centre – Russia, Biomedical Research Centre Slovak Academy of Sciences, Norwegian Institute of Public Health – Norway, Umea University – Sweden
ICGEB Molecular Virology Lab Trieste, A. Marcello
Duration: 2020-2024
Donor
Regione Autonoma Friuli Venezia Giulia – POR FESR
Partners
Vivabiocell, Zeta Research, Università degli Studi di Trieste
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2018-2022
Donor
Regione Autonoma Friuli Venezia Giulia (L.R. 17/2014)
Cardiomiciti di cellule staminali per una cardiologia personalizzata – CardioStem
Partners
Azienda Sanitaria Universitaria Integrata Trieste ASUITS (Struttura complessa di Cardiologia)
ICGEB Molecular Medicine Lab Trieste, M. Giacca
Duration: 2019-2021
Donor
Regione Autonoma Friuli Venezia Giulia, L.R. 19/2000
LaserNET-Strengthening laser therapy as treatment of oral mucositis, stomatitis, dermatitis
Partners
Clinical Centre of Serbia, Inst. Oncology & Radioth. of Serbia, Univ. Children Hosp. of Serbia, Univ. Trieste, Pediatric Hosp. Burlo Garofolo, Trieste
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2018-2021
Donor
SunPharma International
Dengue Vaccine Programme
ICGEB Translational Health Group New Delhi, N. Khanna
Duration: 2016-2021
Donor
SPI Pharma
Dengue Vaccine Programme
ICGEB Recombinant Gene Products Lab New Delhi, N. Khanna
Duration: 2016-2021
Donor
Swiss National Fund
Regenerative strategies for heart disease via targeting the long noncoding transcriptome – SINERGIA
Partner
University of Lausanne Medical School
ICGEB Molecular Medicine Lab Trieste, M. Giacca
Duration: 2017-2021
Donor
Wellcome Trust Alliance
Regulation of host splicing machinery by factors from mycobacterium tuberculosis and its impact on host innate defense mechanism
ICGEB Cellular Immunology Lab New Delhi, D. Kumar
Duration: 2018-2022
Donor
Western Ontario University
Full-length RGNEF and/or “RGNEF leucine–rich domain” as a therapeutic target in ALS
ICGEB Molecular Pathology Lab Trieste, E. Buratti
Duration: 2019-2022
quality education
Donor
Department of Biotechnology (DBT), Government of India
Organizing an International summit on women in STEM
ICGEB Structural Immunology Lab New Delhi, D. Salunke
Duration: 2020-2021
Donor
Elettra-Sincrotrone
Support for A. Falaschi fellows from developing coutries in biology, biophysics, life sciences and biotechnology
ICGEB Research Grants – CRP and Fellowships, Trieste
Duration: 2021-2024
Donor
Italian Agency for Development Cooperation (AICS)
BIOTECHNET – Enhancing biotechnology know-how in the Horn of Africa (AID n.12098)
Duration: 2021-2024
Donor
Ministry of Foreign Affairs and International Cooperation (MAECI), Government of Italy
WE-STAR – PhD and Postdoctoral training scheme for Women Scientists in Africa
Duration: 2021-2022
Donor
Ministry of University and Research (MUR), Government of Italy
Science & the City: da Trieste a Padova, Bergamo e Napoli, ICGEB porta la scienza in piazza
ICGEB Communications, Public Information & Outreach Trieste, S. Kerbavcic
Duration: 2021-2022
Donor
Regione Autonoma Friuli Venezia Giulia, L.R. 17/2014
ComUnicaRe per crescere In SAlute-CURIoSA
Partner
University of Trieste (Dipartimento di Scienze Mediche e Chirurgiche e della Salute)
ICGEB Cardiovascular Biology Lab Trieste, S. Zacchigna
Duration: 2019-2022
Donor
United Nations Office for South-South Cooperation (UNOSSC)
Duration: 2021-2022
Donor
UN Tech Bank
PACTS UNTBLDC-TWAS-ICGEB Joint Proposal for a ProgrAme of CollaboraTions with LDC-PACTS
Duration: 2021-2025
Donor
Wellcome Trust Alliance
Early-Career fellowship programme
ICGEB Emory-Vaccine Programme New Delhi, A. Chandele
Duration: 2020-2025
affordable energy
Donor
Department of Biotechnology (DBT), Government of India
Genetic engineering of microalgae for producing alkanes for further applications
ICGEB Metabolic Engineering Lab New Delhi, S. Kumar Rhode and N. Gaur
Duration: 2020-2022
Donor
Department of Biotechnology (DBT), Government of India
Demonstration of algal chassis for the photo autotrophic production of isoprenoids
ICGEB Omics of Algae Lab New Delhi, P. Jutur
Duration: 2019-2022
Donor
Department of Biotechnology (DBT), Government of India
Indian Marine cyanobacterial host for production of drop-in fuels
ICGEB Microbial Engineering Lab New Delhi, S. Yazdani
Duration: 2019-2022
Donor
Department of Biotechnology (DBT), Government of India
Development of Paenibacillus polymyxa as a platform for production of branched chain alcohols
ICGEB Microbial Engineering Lab New Delhi, S. Yazdani
Duration: 2019-2022
Donor
Department of Biotechnology (DBT), Government of India
Chloroplast metabolic engineering of Artemisia annua for enhancing artemisinin biosynthesis
Partners
Jamia Hamdard University
ICGEB Metabolic Engineering Lab New Delhi, S. Kumar
Duration: 2018-2021
Donor
Department of Biotechnology (DBT), Government of India
Reducing industrial waste from sugar cane processing in India
Partners
University of York (UK), University of Leon (Spain), Jesmond Engineering Ltd (UK)
ICGEB Microbial Engineering Lab New Delhi, S. Yazdani
Duration: 2018-2021
Donor
Nirvana Life Science Inc.
Psilocybin producing S. cerevisiae strain with the yield of 1000 mg/L in laboratory scale fermenter (500ml)
ICGEB Yeast Biofuel Lab New Delhi, N. Gaur
Duration: 2020-2021
Donor
TATA STEEL LIMITED
Carbonaceous gas to fuel by genetically engineered organisms
ICGEB Microbial Engineering Lab New Delhi, S. Yazdani
Duration: 2019-2022
industry innovation
climate action
Promoting biopesticides: a sustainable pest control strategy for climate change adaptation
Donor
South Africa National Research Foundation
ICGEB Biopesticides Lab Cape Town, D. Ndolo
Duration: 2021-2023
partnership for the goals
CUTTiNG 2020
Donor
Ministry of Economic Development, Government of Italy
ICGEB Fundraising TT & Innovation
Duration: 2020-2023