Lithocholic acid

Last modified: Fri Jul 9 14:34:23 BST 2004

Steroid carbon nomenclature

Trivial name: Lithocholic acid
Systematic name: 3alpha-Hydroxy-5ß-cholan-24-oic acid
Molecular formula: C24H40O3
CAS Number: 434-13-9
Merck Index (11th Ed) Number: 5423


Substrate [1]

Pathway: Lithocholic acid -> 6ß-Hydroxylithocholic acid
Reaction: steroid ß-hydroxylation at C6
Enzyme: lithocholic acid 6ß-hydroxylase (steroid 6ß-hydroxylase), CYP3A10
EC 1.14.14.1

Reference

  1. Chang, T.K., Teixeira, J., Gil, G. and Waxman, D.J. (1993) The lithocholic acid 6ß-hydroxylase cytochrome P-450, CYP 3A10, is an active catalyst of steroid-hormone 6ß-hydroxylation. Biochem. J. 291, 429-433.


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