Estrone

Last modified: Fri Jul 9 15:02:12 BST 2004

Steroid carbon nomenclature

Trivial name: Estrone; Estrol; Oestrin; Oestrone
Systematic name: 3ß-Hydroxyestra-1,3,5(10)-trien-17-one
Molecular formula: C18H22O2
CAS Number: 53-16-7
Merck Index (11th Ed) Number: 3660
COMPOUND: C00468

Product

Pathway: Androstenedione -> Estrone + HCOOH
Reaction: aromatase (aromatisation of the A ring and C19 demethylation)
Enzyme: P450arom (aromatase), CYP19
EC 1.14.14.1

Reference

  1. Ruckpaul, K. and Rein, H., Eds. (1990) Frontiers in Biotransformation, vol. 3: Molecular Mechanisms of Adrenal Steroidogenesis and Aspects of Regulation and Application. Taylor & Francis, London.

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