Dehydroepiandrosterone

Last modified: Fri Jul 9 14:34:23 BST 2004

Steroid carbon nomenclature

Trivial name: Dehydroepiandrosterone; Dehydroisoandrosterone; trans-Dehydroandrosterone; DHEA; Prasterone
Systematic name: 3ß-Hydroxyandrost-5-en-17-one
Molecular formula: C19H28O2
CAS Number: 53-43-0
Merck Index (11th Ed) Number: 7710

Product

Pathway: 17alpha-Hydroxypregnenolone -> Dehydroepiandrosterone + Acetate
Reaction: cleavage of steroid C17-C20 bond
Enzyme: P450c17 (steroid 17alpha-hydroxylase/17,20-lyase), CYP17
EC 1.14.99.9

Reference

  1. Ruckpaul, K. and Rein, H., Eds. (1990) Frontiers in Biotransformation, vol. 3: Molecular Mechanisms of Adrenal Steroidogenesis and Aspects of Regulation and Application. Taylor & Francis, London.

Back to the Directory of P450-containing Systems home page: