Aldosterone

Last modified: Tue Jul 6 11:35:33 BST 2004

Steroid carbon nomenclature

Trivial names: Aldosterone; Aldocortin
Systematic name: 11ß,21-Dihydroxy-3,20-dioxopregn-4-en-18-al
Molecular formula: C21H28O5
CAS Number: 52-39-1
Merck Index (11th Ed) Number: 218
COMPOUND: C01780

Product

Pathway: 18-Hydroxycorticosterone -> Aldosterone
Reaction: steroid oxidation at C18
Enzyme: P450c18 (steroid 18-hydroxylase), CYP11B
EC 1.14.15.5

Reference

  1. Ruckpaul, K. and Rein, H., Eds. (1990) Frontiers in Biotransformation, vol. 3: Molecular Mechanisms of Adrenal Steroidogenesis and Aspects of Regulation and Application. Taylor & Francis, London.

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