Ecdysone

Last modified: Tue Jul 6 10:33:06 BST 2004

Steroid carbon nomenclature

Trivial names: Ecdysone; alpha-Ecdysone
Systematic name: (22R)-2ß,3ß,14alpha,22,25-Pentahydroxycholest-7-en-6-one
Molecular formula: C27H44O6
CAS Number: 3604-87-3
Merck Index (11th Ed) Number: 3465


Substrate

Pathway: Ecdysone -> 20-Hydroxyecdysone
Reaction: steroid hydroxylation at C20
Enzyme: ecdysone 20-monooxygenase
EC 1.14.99.22


References

  1. Srivatsan, J., Weirich, M. and Agosin, M. (1990) Cytochrome P-450-catalyzed formation of 20-hydroxy-ecdysone in larval housefly mitochondria. Biochem. Biophys. Res. Commun. 166, 1372-1377.
  2. Chen, J.H., Hara, T., Fisher, M.J. and Rees, H.H. (1994) Immunological analysis of developmental changes in ecdysone 20-mono-oxygenase expression in the cotton leafworm, Spodoptera littoralis. Biochem. J. 299, 711-717.


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