6ß-Hydroxyandrostenedione

Last modified: Tue Jul 6 11:29:32 BST 2004

Steroid carbon nomenclature

Trivial name: 6ß-Hydroxyandrostenedione
Systematic name: 6ß-Hydroxyandrost-4-ene-3,17-dione
Molecular formula: C19H26O3


Product

Pathway: Androstenedione -> 6ß-Hydroxyadrostenedione
Reaction: steroid ß-hydroxylation at C6
Enzyme: steroid 6ß-hydroxylase, CYP3A [1]
EC 1.14.14.1 Enzyme: P450HP, CYP4B1 [2]
EC 1.14.14.1

References

  1. Chang, T.K., Teixeira, J., Gil, G. and Waxman, D.J. (1993) The lithocholic acid 6ß-hydroxylase cytochrome P-450, CYP 3A10, is an active catalyst of steroid-hormone 6ß-hydroxylation. Biochem. J. 291, 429-433.
  2. Waxman, D.J., Lapenson, D.P., Aoyama, T., Gelboin, H.V., Gonzalez, F.J. and Korzekwa, K. (1991) Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s. Arch. Biochem. Biophys. 290, 160-166.


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