Steroid 6ß-hydroxylation

Steroid
	NADPH
6ß-Hydroxysteroid

Steroid carbon nomenclature

Pathway:

• Androstenedione 6ß-Hydroxyandrostenedione
• Lithocholic acid 6ß-Hydroxylithocholic acid
• Progesterone 6ß-Hydroxyprogesterone
• Testosterone 6ß-Hydroxytestosterone

CP31_RAT
CP32_RAT
CP33_HUMAN
CP34_HUMAN
CP35_HUMAN
CP3A_MESAU

CP4B_HUMAN
CP4B_RABIT
CP4B_RAT

References

1. Chang, T.K., Teixeira, J., Gil, G. and Waxman, D.J. (1993) The lithocholic acid 6ß-hydroxylase cytochrome P-450, CYP 3A10, is an active catalyst of steroid-hormone 6ß-hydroxylation. Biochem. J. 291, 429-433.
2. Waxman, D.J., Lapenson, D.P., Aoyama, T., Gelboin, H.V., Gonzalez, F.J. and Korzekwa, K. (1991) Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s. Arch. Biochem. Biophys. 290, 160-166.

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