18-Oxocortisol

Last modified: Tue Jul 6 11:53:33 BST 2004

Steroid carbon nomenclature

Trivial names: 18-Oxocortisol
Systematic name: 11ß,17,21-Trihydroxypregn-4-ene-3,18,20-trione
Molecular formula: C21H28O6

Product

Pathway: 18-Hydroxycortisol -> 18-Oxocortisol
Reaction: steroid oxidation at C18
Enzyme: P450c18 (steroid 18-hydroxylase), CYP11B
EC 1.14.15.5

Reference

  1. Ruckpaul, K. and Rein, H., Eds. (1990) Frontiers in Biotransformation, vol. 3: Molecular Mechanisms of Adrenal Steroidogenesis and Aspects of Regulation and Application. Taylor & Francis, London.

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