16alpha-Hydroxyprogesterone

Last modified: Fri Jul 9 14:30:30 BST 2004

Steroid carbon nomenclature

Trivial names: 16alpha-Hydroxyprogesterone
Systematic name: 16alpha-Hydroxypregn-4-ene-3,20-dione
Molecular formula: C21H30O3
CAS Number: 438-07-3


Product

Pathway: Progesterone -> 16alpha-Hydroxyprogesterone
Reaction: steroid alpha-hydroxylation at C16
Enzyme: steroid 16alpha-hydroxylase, CYP3A [1]
EC 1.14.14.1 Enzyme: P450NMb, CYP2G1 [2]
EC 1.14.14.1

Reference

  1. Waxman, D.J., Lapenson, D.P., Aoyama, T., Gelboin, H.V., Gonzalez, F.J. and Korzekwa, K. (1991) Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s. Arch. Biochem. Biophys. 290, 160-166.
  2. Ding, X. and Coon, M.J. (1994) Steroid metabolism by rabbit olfactory-specific P450 2G1. Arch. Biochem. Biophys. 315, 454-459.


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