15alpha-Hydroxyandrostenedione

Last modified: Tue Jul 6 15:25:31 BST 2004

Steroid carbon nomenclature

Trivial name: 15alpha-Hydroxyandrostenedione
Systematic name: 15alpha-Hydroxyandrost-4-ene-3,17-dione
Molecular formula: C19H26O3

Product [1]

Pathway: Androstenedione -> 15alpha-Hydroxyandrostenedione
Reaction: steroid alpha-hydroxylation at C15
Enzyme: P45015alpha (steroid 15alpha-hydroxylase), CYP2B
EC 1.14.14.4

Reference

  1. Szklarz, G.D., He, Y.Q., Kedzie, K.M., Halpert, J.R. and Burnett, V.L. (1996) Elucidation of amino acid residues critical for unique activities of rabbit cytochrome P450 2B5 using hybrid enzymes and reciprocal site-directed mutagenesis with rabbit cytochrome P450 2B4. Arch. Biochem. Biophys. 327, 308-318.

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