Steroid 11ß-hydroxylation

Last modified: Tue Jul 6 15:28:36 BST 2004

Steroid
NADPH
11ß-Hydroxysteroid

Steroid carbon nomenclature

Pathways:

Reaction: steroid ß-hydroxylation at C11
Enzyme: P450c11 (steroid 11ß-hydroxylase), CYP11B [1]
EC 1.14.15.4 Enzyme: Cochliobolus lunatus P450C.l. (progesterone 11ß-hydroxylase) [2]

References

  1. Ruckpaul, K. and Rein, H., Eds. (1990) Frontiers in Biotransformation, vol. 3: Molecular Mechanisms of Adrenal Steroidogenesis and Aspects of Regulation and Application. Taylor & Francis, London.
  2. Vitas, M., Rozman, D., Komel, R. and Kelly, S.L. (1995) P450 mediated progesterone hydroxylation in Cochliobolus lunatus. J. Biotechnol. 42, 145-150.

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