Steroid 11alpha-hydroxylation

Last modified: Fri Jul 9 14:29:23 BST 2004

Steroid
NADPH
11alpha-Hydroxysteroid


Steroid carbon nomenclature

Pathways:

Reaction: steroid alpha-hydroxylation at C11
Enzyme: P450NMb, CYP2G1 [1]
EC 1.14.14.1 Enzyme: P45011alpha, P450R.n. [2]


References

  1. Ding, X. and Coon, M.J. (1994) Steroid metabolism by rabbit olfactory-specific P450 2G1. Arch. Biochem. Biophys. 315, 454-459.
  2. Breskvar, K., Ferencak, Z. and Hudnik-Plevnik, T. (1995) The role of cytochrome P45011alpha in detoxification of steroids in the filamentous fungus Rhizopus nigricans. J. Steroid Biochem. Mol. Biol. 52, 271-275.


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