Archive of Kirill's P450 Café - 2008
by Kirill Degtyarenko
Last modified: Wed Jan 7 15:09:54 GMT 2009
19 December 2008.
12 December 2008.
Now something about P450-independent reactions (previously, thought to be due
Gruenewald, S., Wahl, B., Bittner, F., Hungeling, H., Kanzow, S., Kotthaus, J.,
Schwering, U., Mendel, R.R. and Clement, B. (2008)
The fourth molybdenum containing enzyme mARC: Cloning and involvement in the
activation of N-hydroxylated prodrugs.
J. Med. Chem. 51, 8173-8177.
5 December 2008.
28 November 2008.
21 November 2008.
14 November 2008.
7 November 2008.
Hlavica, P. (2008)
Assembly of non-natural electron transfer conduits in the cytochrome P450
system: A critical assessment and update of artificial redox constructs
amenable to exploitation in biotechnological areas.
Biotechnol. Adv., in press.
17 October 2008.
10 October 2008.
3 October 2008.
Virus, C. and Bernhardt, R. (2008)
Molecular evolution of a steroid hydroxylating cytochrome P450 using a versatile steroid
detection system for screening.
Lipids 43, 1133-1141.
26 September 2008.
19 September 2008.
12 September 2008.
Kartha, J.S., Skordos, K.W., Sun, H., Hall, C., Easterwood, L.M., Reilly, C.A.,
Johnson, E.F. and Yost, G.S. (2008)
Single mutations change CYP2F3 from a dehydrogenase of
3-methylindole to an oxygenase.
Biochemistry 47, 9756-9770.
5 September 2008.
Bell, S.G., Xu, F., Forward, I., Bartlam, M., Rao, Z. and Wong, L.-L. (2008)
Crystal structure of CYP199A2, a para-substituted benzoic acid oxidizing
cytochrome P450 from Rhodopseudomonas palustris.
J. Mol. Biol. 383, 561-574.
29 August 2008.
Silva, D.C., DeFreitas-Silva, G., Nascimento, E.D., Rebouças, J.S.,
Barbeira, P.J.S., de Carvalho, M.E.M. and Idemori, Y.M. (2008)
Spectral, electrochemical, and catalytic properties of a homologous series of
manganese porphyrins as cytochrome P450 model: The effect of the degree of
J. Inorg. Biochem. 102, 1932-1941.
15 August 2008.
Woithe, K., Geib, N., Meyer, O., Wörtz, T., Zerbe, K. and Robinson, J.A.
Exploring the substrate specificity of OxyB, a phenol coupling P450 enzyme
involved in vancomycin biosynthesis.
Org. Biomol. Chem. 6, 2861-2867.
8 August 2008.
1 August 2008.
25 July 2008.
18 July 2008.
Hao, M., Zhao, Y., Chen, P., Huang, H., Liu, H., Jiang, H., Zhang, R. and
Wang, H. (2008)
Structure-activity relationship and substrate-dependent phenomena in
effects of ginsenosides on activities of drug-metabolizing P450 enzymes.
PLoS ONE 3, e2697.
11 July 2008.
4 July 2008.
27 June 2008.
20 June 2008.
McCoy, J.G., Johnson, H..D, Singh, S., Bingman, C.A., Lei, I.-K., Thorson, J.S.
and Phillips, G.N., Jr. (2008)
Structural characterization of CalO2: A putative orsellinic acid P450
oxidase in the calicheamicin biosynthetic pathway.
Proteins 74, 50-60.
13 June 2008.
Ma, Q. and Lu, A.Y. (2008)
The challenges of dealing with promiscuous drug-metabolizing enzymes, receptors and transporters.
Curr. Drug Metab. 9, 374-383.
6 June 2008.
30 May 2008.
23 May 2008.
16 May 2008.
2 May 2008.
White, M.A., Mast, N., Bjorkhem, I., Johnson, E.F., Stout, C.D. and Pikuleva, I.A. (2008)
Use of complementary cation and anion heavy-atom salt derivatives to solve
the structure of cytochrome P450 46A1.
Acta Crystallogr. D64, 487-495.
25 April 2008.
18 April 2008.
Control of aggressiveness by social regulation of cytochrome P450s?
11 April 2008.
28 March 2008.
Adams, J.S., Chen, H., Chun, R., Ren, S., Wu, S., Gacad, M., Nguyen, L.,
Ride, J., Liu, P., Modlin, R. and Hewison, M. (2007)
Substrate and enzyme trafficking as a means of regulating 1,25-dihydroxyvitamin
D synthesis and action: the human innate immune response.
J. Bone Miner. Res. 22, Suppl. 2, V20-V24.
21 March 2008.
14 March 2008.
7 March 2008.
Sugimoto, H., Shinkyo, R., Hayashi, K., Yoneda, S., Yamada, M., Kamakura, M.,
Ikushiro, S.I., Shiro, Y. and Sakaki, T. (2008)
Crystal structure of CYP105A1 (P450SU-1) in complex with
Biochemistry 47, 4017-4027.
29 February 2008.
Maghzal, G.J., Thomas, S.R., Hunt, N.H. and Stocker, R. (2008)
Cytochrome b5, not superoxide anion radical, is a major
reductant of indoleamine 2,3-dioxygenase in human cells.
J. Biol. Chem. 283, 12014-12025.
22 February 2008.
8 February 2008.
Kimura, I., Nakayama, Y., Yamauchi, H., Konishi, M., Miyake, A., Mori, M.,
Ohta, M., Itoh, N. and Fujimoto, M. (2008)
Neurotrophic activity of neudesin, a novel extracellular heme-binding protein,
is dependent on the binding of heme to its cytochrome
b5-like heme/steroid-binding domain.
J. Biol. Chem. 283, 4323-4331.
1 February 2008.
25 January 2008.
Gonzalez-Kristeller, D.C., Farage, L., Fiorini, L.C., Loomis, W.F. and
da Silva, A.M. (2008)
The P450 oxidoreductase, RedA, controls development beyond the mound stage
in Dictyostelium discoideum.
BMC Dev. Biol. 8, 8.
18 January 2008.
11 January 2008.
Rontein, D., Onillon, S., Herbette, G., Lesot, A., Werck-Reichhart, D., Sallaud, C. and Tissier, A. (2008)
CYP725A4 from yew catalyzes complex structural rearrangment of taxa-4(5)-11(12)-diene into the cyclic ether
J. Biol. Chem. 283, 6067-6075.
4 January 2008.
Newcomb, M., Halgrimson, J.A., Horner, J.H., Wasinger, E.C., Chen, L.X. and Sligar, S.G. (2008)
X-ray absorption spectroscopic characterization of a cytochrome P450 compound II derivative.
Proc. Natl. Acad. Sci. USA 105, 8179-8184.
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