Archive of Kirill's P450 Café - 2007
by Kirill Degtyarenko
Last modified: Mon Jan 7 15:38:44 GMT 2008
21 December 2007.
14 December 2007.
7 December 2007.
30 November 2007.
23 November 2007.
Li, Y.-C., Chiang, C.-W., Yeh, H.-C., Hsu, P.-Y., Whitby, F.G., Wang, L.-H. and
Chan, N.-L. (2007)
Structures of prostacyclin synthase and its complexes with substrate-analog and
inhibitor reveal a ligand-specific heme conformation change.
J. Biol. Chem., in press.
16 November 2007.
9 November 2007.
2 November 2007.
26 October 2007.
19 October 2007.
12 October 2007.
5 October 2007.
28 September 2007.
Huang, W.-C., Westlake, A.C.G., Maréchal, J.-D., Joyce, M.G.,
Moody, P.C.E. and Roberts, G.C.K. (2007)
Filling a hole in cytochrome P450 BM3 improves substrate binding and
J. Mol. Biol. 373, 633-651.
14 September 2007.
7 September 2007.
This week's Café has on the coffee table a special issue of
Drug Metabolism Reviews dedicated to Ron Estabrook
Metabolism Reviews, vol. 39, no. 2 & 3, 2007).
24 August 2007.
17 August 2007.
10 August 2007.
Yasutake, Y., Imoto, N., Fujii, Y., Fujii, T., Arisawa, A. and Tamura, T.
Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena
Biochem. Biophys. Res. Commun. 361, 876-882.
3 August 2007.
27 July 2007.
Bloom, J.D., Lu, Z., Chen, D., Raval, A., Venturelli, O.S. and Arnold, F.H.
Evolution favors protein mutational robustness in sufficiently large
BMC Biology 5, 29.
20 July 2007.
de Rosa, M., Pennati, A., Pandini, V., Monzani, E., Zanetti, G. and
Aliverti, A. (2007)
Enzymatic oxidation of NADP+ to its 4-oxo derivative is a
side-reaction displayed only by the adrenodoxin reductase type of
FEBS J. 274, 3998-4007.
13 July 2007.
6 July 2007.
Makino, M., Sugimoto, H., Shiro, Y., Asamizu, S., Onaka, H. and Nagano, S.
Crystal structures and catalytic mechanism of cytochrome P450 StaP that
produces the indolocarbazole skeleton.
Proc. Natl. Acad. Sci. USA 104, 11591-11596.
29 June 2007.
22 June 2007.
15 June 2007.
8 June 2007.
1 June 2007.
Menzel, R., Yeo, H.L., Rienau, S., Li, S., Steinberg, C.E.W. and
Stürzenbaum, S.R. (2007)
Cytochrome P450s and short-chain dehydrogenases mediate the
toxicogenomic response of PCB52 in the nematode Caenorhabditis
J. Mol. Biol. 370, 1-13.
25 May 2007.
Rosales-Hernández, M., Kispert, L., Torres-Ramírez, E.,
Ramírez-Rosales, D., Zamorano-Ulloa, R. and Trujillo-Ferrara, J.
Electron paramagnetic resonance analyses of biotransformation reactions
with cytochrome P-450 immobilized on mesoporous molecular sieves.
Biotechnol. Lett. 29, 919-924.
18 May 2007.
Dürr, U.H.N., Yamamoto, K., Im, S.-C., Waskell, L. and
Ramamoorthy, A. (2007)
Solid-state NMR reveals structural and dynamical properties of a
membrane-anchored electron-carrier protein, cytochrome b5.
J. Am. Chem. Soc. 129, 6670-6671.
4 May 2007.
Shoji, O., Fujishiro, T., Nakajima, H., Kim, M., Nagano, S., Shiro, Y. and
Watanabe, Y. (2007)
Hydrogen peroxide dependent monooxygenations by tricking the substrate
recognition of cytochrome P45BSβ.
Angew. Chem. Int. Ed. Engl. 46, 3656-3659.
27 April 2007.
Klein, K., Tatzel, S., Raimundo, S., Saussele, T., Hustert, E., Pleiss, J.,
Eichelbaum, M.F. and Zanger, U.M. (2007)
A natural variant of the heme-binding signature (R441C) resulting in complete
loss of function of CYP2D6.
Drug Metab. Dispos. 35, 1247-1250.
20 April 2007.
Chang, M.C.Y., Eachus, R.A., Trieu, W., Ro, D.-K., and Keasling, J.D.
Engineering Escherichia coli for production of functionalized terpenoids
using plant P450s.
Nature Chem. Biol. 3, 274-277.
30 March 2007.
23 March 2007.
16 March 2007.
Gerisch, B., Rottiers, V., Li, D., Motola, D.L., Cummins, C.L., Lehrach, H.,
Mangelsdorf, D.J. and Antebi, A. (2007)
A bile acid-like steroid modulates Caenorhabditis elegans lifespan
through nuclear receptor signaling.
Proc. Natl. Acad. Sci. USA 104, 5014-5019.
9 March 2007.
Milani, M., Balconi, E., Aliverti, A., Mastrangelo, E., Seeber, F.,
Bolognesi, M. and Zanetti, G. (2007)
Ferredoxin-NADP+ reductase from Plasmodium falciparum
undergoes NADP+-dependent dimerization and inactivation:
Functional and crystallographic analysis.
J. Mol. Biol. 367, 501-513.
2 March 2007.
Feenstra, K.A., Starikov, E.B., Urlacher, V.B., Commandeur, J.N.M. and
Vermeulen, N.P.E. (2007)
Combining substrate dynamics, binding statistics, and energy barriers to
rationalize regioselective hydroxylation of octane and lauric acid by
CYP102A1 and mutants.
Protein Science 16, 420-431.
23 February 2007.
Frank, B., Knauber, J., Steinmetz, H., Scharfe, M., Blöcker, H.,
Beyer, S. and Müller, R. (2007)
Spiroketal polyketide formation in Sorangium: identification and
analysis of the biosynthetic gene cluster for the highly cytotoxic spirangienes.
Chemistry & Biology 14, 221-233.
16 February 2007.
9 February 2007.
Bonifacio, A., Keizers, P.H.J., Vermeulen, N.P.E., Commandeur, J.N.M.,
Gooijer, C. and van der Zwan, G. (2007)
Surface-enhanced resonance Raman scattering of cytochrome P450-2D6 on
coated silver hydrosols.
Langmuir 23, 1860-1866.
2 February 2007.
26 January 2007.
Liu, Y., Dettin, L., Folmer, J., Zirkin, B. and Papadopoulos, V.
Abnormal morphology of spermatozoa in cytochrome P450
17α-hydroxylase/17, 20-lyase (CYP17) deficient mice.
J. Androl. 28, 453-460.
19 January 2007.
12 January 2007.
5 January 2007.
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