Archive of Kirill's P450 Café - 2002
by Kirill Degtyarenko
Last modified: Fri Dec 5 16:37:07 GMT 2003
20 December 2002.
- Mifsud, W. and Bateman, A. (2002)
Membrane-bound progesterone receptors contain a cytochrome
b5-like ligand-binding domain.
Genome Biol. 3, 0068.
13 December 2002.
6 December 2002.
29 November 2002.
22 November 2002.
Leys, D., Mowat, C.G., McLean, K.J., Richmond, A., Chapman, S.K.,
Walkinshaw, M.D. and Munro, A.W. (2003)
Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 Å
reveals novel features of cytochrome P450.
J. Biol. Chem. 278, 5141-5147.
15 November 2002.
8 November 2002.
1 November 2002.
Yano, J.K., Blasco, F., Li, H., Schmid, R.D., Henne, A. and Poulos, T.L. (2003)
Preliminary characterization and crystal structure of a thermostable
cytochrome P450 from Thermus thermophilus.
J. Biol. Chem. 278, 608-616.
25 October 2002.
18 October 2002.
11 October 2002.
4 October 2002.
27 September 2002.
20 September 2002.
This review appears in the special issue on
Advances in the Inorganic Biochemistry of Cytochrome P450
(Journal of Inorganic Biochemistry vol. 91, no. 4, 2002).
This issue contains selected papers presented on
12th International Conference on Cytochrome P450,
11-15 September 2001, La Grande Motte, France.
13 September 2002.
6 September 2002.
This review appears in the Special Issue on AhR biology
(Chemico-Biological Interactions vol. 141, no. 1-2, 2002).
Hahn, M.E. (2002)
Aryl hydrocarbon receptors: diversity and evolution.
Chem. Biol. Interact. 141, 131-160.
30 August 2002.
Dunn, A.R., Hays, A.-M.A., Goodin, D.B., Stout, C.D., Chiu, R., Winkler, J.R.
and Gray, H. (2002)
Fluorescent probes for cytochrome P450 structural characterization and
J. Am. Chem. Soc. 124, 10254-10255.
23 August 2002.
Grogan, G., Roberts, G.A., Parsons, S., Turner, N.J. and Flitsch, S.L. (2002)
P450camr, a cytochrome P450 catalysing the stereospecific
6-endo-hydroxylation of (1R)-(+)-camphor.
Appl. Microbiol. Biotechnol. 59, 449-454.
16 August 2002.
Taoka, S., Lepore, B.W., Kabil, Ö., Ojha, S., Ringe, D. and Banerjee, R.
Human cystathionine ß-synthase is a heme sensor protein. Evidence that the
redox sensor is heme and not the vicinal cysteines in the CXXC motif seen in
the crystal structure of the truncated enzyme.
Biochemistry 41, 10454-10461.
9 August 2002.
2 August 2002.
Gan, J.-H., Wu, J., Wang, Z.-Q., Wang, Y.-H., Huang, Z.-X. and Xia, Z.-X.
Structures of V45E and V45Y mutants and structure comparison of a variety of
cytochrome b5 mutants.
Acta Crystallogr. D58, 1298-1306.
26 July 2002.
19 July 2002.
At the C-terminus, the P450 is fused to a reductase domain which displays
sequence conservation for dioxygenase reductase proteins.
12 July 2002.
Fradera, X., de la Cruz, X., Silva, C.H.T.P., Gelpí, J.L., Luque, F.J.
and Orozco, M. (2002)
Ligand-induced changes in the binding sites of proteins.
Bioinformatics 18, 939-948.
5 July 2002.
21 June 2002.
Beilke, D., Weiss, R., Löhr, F., Pristovsek, P., Hannemann, F.,
Bernhardt, R. and Rüterjans, H. (2002)
A new electron transport mechanism in mitochondrial steroid hydroxylase systems
based on structural changes upon the reduction of adrenodoxin.
Biochemistry 41, 7969-7978.
14 June 2002.
31 May 2002.
24 May 2002.
Lamb, D.C., Fowler, K., Kieser, T., Manning, N., Podust, L.M., Waterman, M.R.,
Kelly, D.E. and Kelly, S.L. (2002)
Sterol 14-demethylase activity in
Streptomyces coelicolor A3(2) is associated with an unusual member of
the CYP51 gene family.
Biochem. J. 364, 555-562.
17 May 2002.
10 May 2002.
3 May 2002.
26 April 2002.
- Dawson, J.H., Pond, A.E. and Roach, M.P. (2002)
H93G myoglobin cavity mutant as versatile template for modeling heme proteins:
Magnetic circular dichroism studies of thiolate- and imidazole-ligated
Biopolymers 67, 200-206.
This review appears in the Special Issue: Selections from the 9th European
Conference on the Spectroscopy of Biological Materials
vol. 67, no. 4-5, 2002).
19 April 2002.
- Guallar, V., Gherman, B.F., Lippard, S.J. and Friesner, R.A. (2002)
Quantum chemical studies of methane monooxygenase: comparision with P450.
Curr. Opin. Chem. Biol. 6, 236-242.
This review appears in the Guest section on Computational bioinorganic
chemistry (Part II)
(Current Opinion in Chemical Biology vol. 6, no. 2, 2002).
12 April 2002.
Mowat, C.G., Leys, D., McLean, K.J., Rivers, S.L., Richmond, A., Munro, A.W.,
Ortiz Lombardia, M., Alzari, P.M., Reid, G.A., Chapman, S.K. and
Walkinshaw, M.D. (2002)
Crystallization and preliminary crystallographic analysis of a novel cytochrome
P450 from Mycobacterium tuberculosis.
Acta Crystallogr. D58, 704-705.
P450 MT2 (CYP121) has been crystallised. The native crystal diffracts to
1.6 Å resolution and Hg-derivative crystal data were collected to a
resolution of 2.5 Å.
5 April 2002.
Yao, P., Wang, Y.-H., Sun, B.-Y., Xie, Y., Hirota, S., Yamauchi, O. and
Huang, Z.-X. (2002)
Kinetic studies on the oxidation of cytochrome b5 Phe35
mutants with cytochrome c, plastocyanin and inorganic complexes.
J. Biol. Inorg. Chem. 7, 375-383.
29 March 2002.
22 March 2002.
15 March 2002.
Champier, L., Sibille, N., Bersch, B., Brutscher, B., Blackledge, M. and
Covès, J. (2002)
Reactivity, secondary structure, and molecular topology of the
Escherichia coli sulfite reductase flavodoxin-like domain.
Biochemistry 41, 3770-3780.
8 March 2002.
1 March 2002.
Gilardi, G., Meharenna, Y.T., Tsotsou, G.E., Sadeghi, S.J., Fairhead, M. and
Giannini, S. (2002)
Molecular Lego: design of molecular assemblies of P450 enzymes for
Biosensors and Bioelectronics 17, 133-145.
22 February 2002.
Watkins, R.E., Wisely, G.B., Moore, L.B., Collins, J.L., Lambert, M.H.,
Williams, S.P., Willson, T.M., Kliewer, S.A. and Redinbo, M.R. (2001)
The human nuclear xenobiotic receptor PXR: structural determinants of directed
Science 292, 2329-2333.
15 February 2002.
8 February 2002.
Matsunaga, I., Yamada, A., Lee, D.-S., Obayashi, E., Fujiwara, N.,
Kobayashi, K., Ogura, H. and Shiro, Y. (2002)
Enzymatic reaction of hydrogen peroxide-dependent peroxygenase cytochrome P450s:
kinetic deuterium isotope effects and analyses by resonance Raman spectroscopy.
Biochemistry 41, 1886-1892.
1 February 2002.
25 January 2002.
A biodevice involving thiolated ssDNA and engineered cytochrome
b5 linked through a cisplatin bridge is described.
18 January 2002.
11 January 2002.
4 January 2002.
Lewis, D.F.V. and Dickins, M. (2002)
Factors influencing rates and clearance in P450-mediated reactions: QSARs for
substrates of the xenobiotic-metabolizing hepatic microsomal P450s.
Toxicology 170, 45-53.
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