Archive of Kirill's P450 Café - 2000
By Kirill Degtyarenko
Last modified: Fri Apr 16 16:59:16 BST 2004
22 December 2000.
- Gutierrez, A., Doehr, O., Paine, M., Wolf, C.R., Scrutton, N.S. and
Roberts, G.C.K. (2000)
Trp-676 facilitates nicotinamide coenzyme exchange in the reductive
half-reaction of human cytochrome P450 reductase: properties of the soluble
W676H and W676A mutant reductases.
Biochemistry 39, 15990-15999.
15 December 2000.
1 December 2000.
- Blankman, J.I., Shahzad, N., Dangi, B., Miller, C.J. and Guiles, R.D.
Voltammetric probes of cytochrome electroreactivity: the effect of the protein
matrix on outer-sphere reorganization energy and electronic coupling probed
through comparisons with the behavior of porphyrin complexes.
Biochemistry 39, 14799-14805.
24 November 2000.
- Senda, T., Yamada, T., Sakurai, N., Kubota, M., Nishizaki, T., Masai, E.,
Fukuda, M. and Mitsuidagger, Y. (2000)
Crystal structure of NADH-dependent ferredoxin reductase component in biphenyl
J. Mol. Biol. 304, 397-410.
17 November 2000.
- Ogliaro, F., Cohen, S., Filatov, M., Harris, N. and Shaik, S. (2000)
The high-valent compound of cytochrome P450: the nature of the Fe-S bond and
the role of the thiolate ligand as an internal electron donor.
Angew. Chem. Int. Ed. 39, 3851-3855.
10 November 2000.
After a very long break, let's start again...
Hajdu, J., Neutze, R., Sjögren, T., Edman, K., Szöke, A.,
Wilmouth, R.C. and Wilmot CM. (2000)
Analyzing protein functions in four dimensions.
Nature Struct. Biol. 7, 1006-1012.
6 October 2000.
29 September 2000.
22 September 2000.
- Miller, W.L. and Portale, A.A. (2000)
Vitamin D 1-hydroxylase.
Trends Endocrinol. Metab. 11, 315-319.
15 September 2000.
- Powell, K.S. and Latterich, M. (2000)
The making and breaking of the endoplasmic reticulum.
Traffic 1, 689-694.
8 September 2000.
- Reipa, V., Holden, M.J., Mayhew, M.P. and Vilker, V.L. (2000)
Temperature dependence of the formal reduction potential of putidaredoxin.
Biochim. Biophys. Acta 1459, 1-9.
1 September 2000.
25 August 2000.
18 August 2000.
Yano, J.K., Koo, L.S., Schuller, D.J., Li, H., Ortiz De Montellano, P.R. and
Poulos, T.L. (2000)
Crystal structure of a thermophilic cytochrome P450 from the archaeon
J. Biol. Chem. 275, 31086-31092.
11 August 2000.
Cytochrome b5 is used as a case system.
4 August 2000.
- Munro, A.W., Taylor, P. and Walkinshaw, M.D. (2000)
Structures of redox enzymes.
Curr. Opin. Biotechnol. 11, 369-376.
21 July 2000.
- Grinberg, A.V., Hannemann, F., Schiffler, B., Müller, J., Heinemann, U.
and Bernhardt, R. (2000)
Adrenodoxin: Structure, stability, and electron transfer properties.
Proteins 40, 590-612.
14 July 2000.
Taura, K.-i., Yamada, H., Hagino, Y., Ishii, Y., Mori, M.-a. and Oguri, K.
Interaction between cytochrome P450 and other drug-metabolizing enzymes:
Evidence for an association of CYP1A1 with microsomal epoxide hydrolase and
Biochem. Biophys. Res. Commun. 273, 1048-1052.
7 July 2000.
30 June 2000.
This is my pleasure to present a paper by my former colleagues:
23 June 2000.
Sperling, P., Lee, M., Girke, T., Zähringer, U., Stymne, S. and Heinz, E.
A bifunctional 6-fatty
acyl acetylenase/desaturase from the moss Ceratodon purpureus:
A new member of the cytochrome b5 superfamily.
Eur. J. Biochem. 267, 3801-3811.
16 June 2000.
9 June 2000.
- Scherlis, D.A., Cymeryng, C.B. and Estrin, D.A. (2000)
Nitric oxide binding to ferric cytochrome P450: A computational study.
Inorg. Chem. 39, 2352-23592.
2 June 2000.
26 May 2000.
White, J.A., Ramshaw, H., Taimi, M., Stangle, W., Zhang, A., Everingham, S.,
Creighton, S., Tam, S.-P., Jones, G. and Petkovich, M. (2000)
Identification of the human cytochrome P450, P450RAI-2, which is predominantly
expressed in the adult cerebellum and is responsible for all-trans-retinoic
Proc. Natl. Acad. Sci. USA 97, 6403-6408.
19 May 2000.
- Ihara, M., Takahashi, S., Ishimori, K. and Morishima, I. (2000)
Functions of fluctuation in the heme-binding loops of cytochrome
b5 revealed in the process of heme incorporation.
Biochemistry 39, 5961-5970
12 May 2000.
Wittstock, U. and Halkier, B.A. (2000)
Cytochrome P450 CYP79A2 from Arabidopsis thaliana L. catalyzes the
conversion of L-phenylalanine to phenylacetaldoxime in the
biosynthesis of benzylglucosinolate.
J. Biol. Chem. 275, 14659-14666.
5 May 2000.
21 April 2000.
14 April 2000.
Honkakoski, P. and Negishi, M. (2000)
Regulation of cytochrome P450 (CYP) genes by nuclear receptors.
Biochem. J. 347, 321-337.
7 April 2000.
The atomic coordinates have been deposited in the PDB:
31 March 2000.
- Newcomb, M., Shen, R., Choi, S.-Y., Toy, P.H., Hollenberg, P.F.,
Vaz, A.D.N. and Coon, M.J. (2000)
Cytochrome P450-catalyzed hydroxylation of mechanistic probes that distinguish
between radicals and cations. Evidence for cationic but not for radical
J. Am. Chem. Soc. 122, 2677-2686.
24 March 2000.
- Zou, M.-H., Daiber, A., Peterson, J.A., Shoun, H. and Ullrich, V. (2000)
Rapid reactions of peroxynitrite with heme-thiolate proteins as the basis for
protection of prostacyclin synthase from inactivation by nitration.
Arch. Biochem. Biophys. 376, 149-155.
17 March 2000.
10 March 2000.
- Harford-Cross, C.F., Carmichael, A.B., Allan, F.K., England, P.A.,
Rouch, D.A. and Wong, L.-L. (2000)
Protein engineering of cytochrome P450cam (CYP101) for the oxidation
of polycyclic aromatic hydrocarbons.
Protein Engineering 13, 121-128.
3 March 2000.
- van Mierlo, C.P.M., van den Oever, J.M.P. and Steensma, E. (2000)
Apoflavodoxin (un)folding followed at the residue level by NMR.
Protein Science 9, 145-157.
25 Febuary 2000.
- Capdevila, J.H., Falck, J.R. and Harris, R.C. (2000)
Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional
properties of the arachidonate monooxygenase.
J. Lipid Res. 41, 163-181.
18 Febuary 2000.
The structure of first mammalian P450 is solved!
Thanks to Dan Udwary for sending this reference.
11 Febuary 2000.
Loew, G.H. and Harris, D.L. (2000)
Role of the heme active site and protein environment in structure, spectra, and
function of the cytochrome P450s.
Chem. Rev. 100, 407-420.
This review appears in the special issue of Chemical Reviews
on Computational Transition Metal Chemistry
(Chemical Reviews vol. 100, no. 2, 2000).
4 Febuary 2000.
28 January 2000.
Zou, J., Hallberg, B.M., Bergfors, T., Oesch, F., Arand, M., Mowbray, S.L. and
Jones, T.A. (2000)
Structure of Aspergillus niger epoxide hydrolase at 1.8 Å
resolution: implications for the structure and function of the mammalian
microsomal class of epoxide hydrolases.
Structure 8, 111-122.
21 January 2000.
14 January 2000.
- Filatov, M., Harris, N. and Shaik, S. (1999)
On the "rebound" mechanism of alkane hydroxylation by cytochrome P450:
Electronic structure of the intermediate and the electron transfer character
in the rebound step.
Angew. Chem. Int. Ed. 38, 3510-3512.
7 January 2000.
- Mouro, C., Bondon, A., Jung, C., De Certaines, J.D. and Simonneaux, G.
Assignment of heme methyl 1H-NMR resonances of high-spin and
low-spin ferric complexes of cytochrome P450cam using one-dimensional and
two-dimensional paramagnetic signals enhancement (PASE) magnetization transfer
Eur. J. Biochem. 267, 216-221.
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