Archive of Kirill's P450 Café - 1999
By Kirill Degtyarenko
Last modified: Thu Apr 15 13:36:46 BST 2004
24 December 1999.
Merry Christmas and a Happy Year
17 December 1999.
- Ma, D., Wu, Y., Qian, C., Tang, W., Wang, Y.-H., Wang, W.-H., Lu, J.-X.,
Xie, Y. and Huang, Z.-X. (1999)
Effects of some charged amino acid mutations on the electron self-exchange
kinetics of cytochrome b5.
Inorg. Chem. 38, 5749-5754.
10 December 1999.
- Contzen, J. and Jung, C. (1999)
Changes in secondary structure and salt links of cytochrome P450cam
induced by photoreduction: a Fourier transform infrared spectroscopic study.
Biochemistry 38, 16253-16260.
3 December 1999.
Note that this allene oxide synthase is not a P450.
26 November 1999.
Gelboin, H.V., Krausz, K.W., Gonzalez, F.J. and Yang, T.J. (1999)
Inhibitory monoclonal antibodies to human cytochrome P450 enzymes: a new avenue
for drug discovery.
Trends Pharm. Sci. 20, 432-438.
19 November 1999.
- Davydov, R.M., Macdonald, I.D.G., Makris, T.M., Sligar, S.G. and
Hoffman, B.M. (1999)
EPR and ENDOR of catalytic intermediates in cryoreduced native and mutant
oxy-cytochromes P450cam: Mutation-induced changes in the proton delivery system.
J. Am. Chem. Soc. 121, 10654-10655.
12 November 1999.
Tudzynski, B. (1999)
Biosynthesis of gibberellins in Gibberella fujikuroi: biomolecular
Appl. Microbiol. Biotechnol. 52, 298-310.
5 November 1999.
- Payne, V.A., Chang, Y.-T. and Loew, G.H. (1999a)
Homology modeling and substrate binding study of human CYP2C9 enzyme.
Proteins 37, 176-190.
- Payne, V.A., Chang, Y.-T. and Loew, G.H. (1999b)
Homology modeling and substrate binding study of human CYP2C18 and CYP2C19
Proteins 37, 204-217.
29 October 1999.
Sawada, N., Sakaki, T., Kitanaka, S., Takeyama, K.-i., Kato, S. and Inouye, K.
Enzymatic properties of human 25-hydroxyvitamin D3
1-hydroxylase: Coexpression with
adrenodoxin and NADPH-adrenodoxin reductase in Escherichia coli.
Eur. J. Biochem. 265, 950-956.
22 October 1999.
Deng, T.-j., Proniewicz, L.M., Kincaid, J.R., Yeom, H., Macdonald, I.D.G. and
Sligar, S.G. (1999)
Resonance Raman studies of cytochrome P450BM3 and its
complexes with exogenous ligands.
Biochemistry 38, 13699-13706.
15 October 1999.
8 October 1999.
Akashi, T., Matsumura, T., Ideguchi, T., Iwakiri, K.-i., Kawakatsu, T.,
Taniguchi, I. and Hase, T. (1999)
Comparison of the electrostatic binding sites on the surface of ferredoxin for
two ferredoxin-dependent enzymes, ferredoxin-NADP+ reductase and
J. Biol. Chem. 274, 29399-29405.
1 October 1999.
- Schröder, G., Unterbusch, E., Kaltenbach, M., Schmidt, J., Strack, D.,
De Luca, V. and Schröder, J. (1999)
Light-induced cytochrome P450-dependent enzyme in indole alkaloid biosynthesis:
FEBS Lett. 458, 97-102.
24 September 1999.
- Zhu, Q.-s., von Dippe, P., Xing, W. and Levy, D. (1999)
Membrane topology and cell surface targeting of microsomal epoxide hydrolase.
Evidence for multiple topological orientations.
J. Biol. Chem. 274, 27898-27904.
17 September 1999.
- Bertini, I., Luchinat, C., Parigi, G. and Walker, F.A. (1999)
Heme methyl 1H chemical shifts as structural parameters in some
lowspin ferriheme proteins.
J. Biol. Inorg. Chem. 4, 515-519.
10 September 1999.
3 September 1999.
Humphreys, J.M., Hemm, M.R. and Chapple, C. (1999)
New routes for lignin biosynthesis defined by biochemical characterization of
recombinant ferulate 5-hydroxylase, a multifunctional cytochrome P450-dependent
Proc. Natl. Acad. Sci. USA 96, 10045-10050.
20 August 1999.
13 August 1999.
- Posti, K., Leinonen, S., Tetri, S., Kottari, S., Viitala, P., Pelkonen, O.
and Raunio, H. (1999)
Modulation of murine phenobarbital-inducible CYP2A5, CYP2B10 and CYP1A
enzymes by inhibitors of protein kinases and phosphatases.
Eur. J. Biochem. 264, 19-26.
6 August 1999.
- Fahnenschmidt, M., Rau, H.K., Bittl, R., Haehnel, W. and Lubitz, W. (1999)
Characterization of a de novo designed heme protein by EPR and ENDOR
Chem. Eur. J. 5, 2327-2334.
30 July 1999.
- Drapier, J.-C. and Ducrocq, C. [Coordinators] (1999)
Molecular and functional modifications by nitric oxide and its derivatives.
Cell. Mol. Life Sci. 55, 1001-1112.
23 July 1999.
16 July 1999.
"For the peroxidase type of conversions the Fe to Mn replacement resulted in a
less than 10-fold decrease in the activity at optimal pH, whereas the aniline
para-hydroxylation is reduced at least 30-fold."
Primus, J.-L., Boersma, M.G., Mandon, D., Boeren, S., Veeger, C., Weiss, R.
and Rietjens, I.M.C.M. (1999)
The effect of iron to manganese substitution on microperoxidase 8 catalysed
peroxidase and cytochrome P450 type of catalysis.
J. Biol. Inorg. Chem. 4, 274-283.
9 July 1999.
- Lamb, D.C., Kelly, D.E., Venkateswarlu, K., Manning, N.J., Bligh, H.F.J.,
Schunck, W.-H. and Kelly, S.L. (1999)
Generation of a complete, soluble, and catalytically active sterol
Biochemistry 38, 8733-8738.
2 July 1999.
25 June 1999.
- Zaphiropoulos, P.G. (1999)
RNA molecules containing exons originating from different members of the
cytochrome P450 2C gene subfamily (CYP2C) in human epidermis and liver.
Nucleic Acids Res. 27, 2585-2590.
18 June 1999.
11 June 1999.
- Zhukov, A. and Ingelman-Sundberg, M. (1999)
Relationship between cytochrome P450 catalytic cycling and stability:
Fast degradation of ethanol-inducible cytochrome P450 2E1 (CYP2E1) in
hepatoma cells is abolished by inactivation of its electron donor
NADPH-cytochrome P450 reductase.
Biochem. J. 340, 453-458.
4 June 1999.
- Chang, F.-C. and Swenson, R.P. (1999)
The midpoint potentials for the oxidized-semiquinone couple for Gly57
mutants of the Clostridium beijerinckii flavodoxin correlate with
changes in the hydrogen-bonding interaction with the proton on N(5) of
the reduced flavin mononucleotide cofactor as measured by NMR chemical shift
Biochemistry 38, 7168-7176.
28 May 1999.
14 May 1999.
Ito, S., Matsuoka, T., Watanabe, I., Kagasaki, T., Serizawa, N. and
Hata, T. (1999)
Crystallization and preliminary X-ray diffraction analysis of cytochrome
P450sca-2 from Streptomyces carbophilus involved in
production of pravastatin sodium, a tissue-selective inhibitor of HMG-CoA
Acta Crystallogr. D55, 1209-1211.
7 May 1999.
- Maldotti, A., Andreotti, L., Molinari, A. and Carassiti, V. (1999)
Photochemically driven models of oxygenases based on the use of iron porphyrins.
J. Biol. Inorg. Chem. 4, 154-161.
30 April 1999.
- Parikh, A., Josephy, P.D. and Guengerich, F.P. (1999)
Selection and characterization of human cytochrome P450 1A2 mutants with
altered catalytic properties.
Biochemistry 38, 5283-5289 .
23 April 1999.
Noble, M.A., Miles, C.S., Chapman, S.K., Lysek, D.A., Mackay, A.C., Reid, G.A.,
Hanzlik, R.P. and Munro, A.W. (1999)
Roles of key active-site residues in flavocytochrome P450 BM3.
Biochem. J. 339, 371-379.
16 April 1999.
Results of the study "suggest a possible implication of NOSs in the oxidative
metabolism of certain classes of xenobiotics".
- Renodon-Cornière, A., Boucher, J.-L., Dijols, S., Stuehr, D.J. and
Mansuy, D. (1999)
Efficient formation of nitric oxide from selective oxidation of N-aryl
N'-hydroxyguanidines by inducible nitric oxide synthase.
Biochemistry 38, 4663-4668.
9 April 1999.
Shimada, H., Nagano, S., Ariga, Y., Unno, M., Egawa, T., Hishiki, T.,
Ishimura, Y., Masuya, F., Obata, T. and Hori, H. (1999)
Putidaredoxin-cytochrome P450cam interaction. Spin state of
the heme iron modulates putidaredoxin structure.
J. Biol. Chem. 274, 9363-9369.
1 April 1999.
This review appears in
Bio-inorganic Chemistry issue of
Current Opinion in Chemical Biology.
- Poulos, T.L., Li, H. and Raman, C.S. (1999)
Heme-mediated oxygen activation in biology: cytochrome c oxidase and
nitric oxide synthase.
Curr. Opin. Chem. Biol. 3, 131-137.
26 March 1999.
- Ueno, T., Nishikawa, N., Moriyama, S., Adachi, S., Lee, K., Okamura, T.-a.,
Ueyama, N. and Nakamura, A. (1999)
Role of the invariant peptide fragment forming NH···S hydrogen
bonds in the active site of cytochrome P-450 and chloroperoxidase:
Synthesis and properties of Cys-containing peptide Fe(III) and Ga(III)
(octaethylporphinato) complexes as models.
Inorg. Chem. 38, 1199-1210.
19 March 1999.
- Haining, R.L., Jones, J.P., Henne, K.R., Fisher, M.B., Koop, D.R.,
Trager, W.F. and Rettie, A.E. (1999)
Enzymatic determinants of the substrate specificity of CYP2C9:
Role of B'-C loop residues in providing the
-stacking anchor site for warfarin
Biochemistry 38, 3187-3196.
12 March 1999.
- Wang, P.-F., Arscott, L.D., Gilberger, T.-W., Müller, S. and
Williams, C.H., Jr. (1999)
Thioredoxin reductase from Plasmodium falciparum: evidence for
interaction between the C-terminal cysteine residues and the active site
Biochemistry 38, 3187-3196.
5 March 1999.
Grigoryev, D.N., Kato, K., Njar, V.C.O., Long, B.J., Ling, Y.-Z., Wang, X.,
Mohler, J. and Brodie, A.M.H. (1999)
Cytochrome P450c17-expressing Escherichia coli as a
first-step screening system for
Anal. Biochem. 267, 319-330.
26 February 1999.
Koenigs, L.L., Peter, R.M., Hunter, A.P., Haining, R.L., Rettie, A.E.,
Friedberg, T., Pritchard, M.P., Shou, M., Rushmore, T.H. and Trager, W.F.
Electrospray ionization mass spectrometric analysis of intact cytochrome P450:
Identification of tienilic acid adducts to P450 2C9.
Biochemistry 38, 2312-2319.
19 February 1999.
12 February 1999.
- Huang, L., Abu-Soud, H.M., Hille, R. and Stuehr, D.J. (1999)
Nitric oxide-generated P420 nitric oxide synthase: Characterization and
roles for tetrahydrobiopterin and substrate in protecting against or reversing
the P420 conversion.
Biochemistry 38, 1912-1920.
5 February 1999.
28 January 1999.
- Jung, Y.-S., Roberts, V.A., Stout, C.D. and Burgess, B.K. (1999)
Complex formation between Azotobacter vinelandii ferredoxin I and its
physiological electron donor NADPH-ferredoxin reductase.
J. Biol. Chem. 274, 2978-2987.
22 January 1999.
- Macdonald, I.D.G., Sligar, S.G., Christian, J.F., Unno, M. and
Champion, P.M. (1999)
Identification of the Fe-O-O bending mode in oxycytochrome P450cam by resonance
J. Am. Chem. Soc. 121, 376-380.
15 January 1999.
- Audergon, C., Iyer, K.R., Jones, J.P., Darbyshire, J.F. and Trager, W.F.
Experimental and theoretical study of the effect of active-site constrained
substrate motion on the magnitude of the observed intramolecular isotope effect
for the P450 101 catalyzed benzylic hydroxylation of isomeric xylenes and
J. Am. Chem. Soc. 121, 41-47.
8 January 1999.
Oesterheld, J.R. (1998)
A review of developmental aspects of cytochrome P450.
J. Child Adolesc. Psychopharmacol. 8, 161-174.
1 January 1999.
Tian, Y., Ke, S., Denison, M.S., Rabson, A.B. and Gallo, M.A. (1999)
Ah Receptor and NF-B interactions, a
potential mechanism for dioxin toxicity.
J. Biol. Chem. 274, 510-515.
Back to Kirill's P450 Café
Kirill's P450 Café - 2000
Kirill's P450 Café - 1998
Kirill's P450 Café - 1997
Kirill's Paper of the Week
Kirill's Review of the Week
Back to the Directory of P450-containing Systems home page: