Archive of Kirill's P450 Café - 1998
By Kirill Degtyarenko
Last modified: Thu Apr 15 13:42:51 BST 2004
25 December 1998.
Louërat-Oriou, B., Perret, A. and Pompon, D. (1998)
Differential redox and electron-transfer properties of purified yeast,
plant and human NADPH-cytochrome P-450 reductases highly modulate
cytochrome P-450 activities.
Eur. J. Biochem. 258, 1040-1049.
18 December 1998.
Grinberg, A.V. and Bernhardt, R. (1998)
Effect of replacing a conserved proline residue on the function and stability
of bovine adrenodoxin.
Protein Engineering 11, 1057-1064.
11 December 1998.
Hart-Davis, J., Battioni, P., Boucher, J.-L. and Mansuy, D. (1998)
New catalytic properties of iron porphyrins: Model systems for cytochrome
P450-catalyzed dehydration of aldoximes.
J. Am. Chem. Soc. 120, 12524-12530.
4 December 1998.
- Walsh, M.A., McCarthy, A., O'Farrell, P.A., McArdle, P., Cunningham, P.D.,
Mayhew, S.G. and Higgins, T.M. (1998)
X-ray crystal structure of the Desulfovibrio vulgaris (Hildenborough)
Eur. J. Biochem. 258, 362-371.
27 November 1998.
Aissaoui, H., Bachmann, R., Schweiger, A. and Woggon, W.-D. (1998)
On the origin of the low-spin character of cytochrome P450cam in the resting
state - Investigations of enzyme models with pulse EPR and ENDOR spectroscopy.
Angew. Chem. Int. Ed. 37, 2998-3002.
(163 Kb PDF file)
20 November 1998.
Kuroda, R., Ikenoue, T., Honsho, M., Tsujimoto, S., Mitoma, J.-y. and Ito, A.
Charged amino acids at the carboxyl-terminal portions determine the
intracellular locations of two isoforms of cytochrome b5.
J. Biol. Chem. 273, 31097-31102.
13 November 1998.
Naito, N.R., Huang, H., Sturgess, A.W., Nocek, J.M. and Hoffman, B.M. (1998)
Binding and electron transfer between cytochrome b5 and the
hemoglobin - and
ß-subunits through the use of [Zn, Fe] hybrids.
J. Am. Chem. Soc. 120, 11256-11262.
6 November 1998.
30 October 1998.
This is the first report of the potentiometric analysis of the full
E. coli [NAD(P)Hflavodoxin NADP+ oxidoreductaseflavodoxin]
electron transfer chain.
McIver, L., Leadbeater, C., Campopiano, D.J., Baxter, R.L., Daff, S.N.,
Chapman, S.K. and Munro, A.W. (1998)
Characterisation of flavodoxin NADP+ oxidoreductase and flavodoxin
- Key components of electron transfer in Escherichia coli.
Eur. J. Biochem. 257, 577-585.
23 October 1998.
Betlach, M.C., Kealey, J.T., Betlach, M.C., Ashley, G.W. and McDaniel, R.
Characterization of the macrolide P-450 hydroxylase from Streptomyces
venezuelae which converts narbomycin to picromycin.
Biochemistry 37, 14937-14942.
16 October 1998.
See also comment in Nature:
- Howlett, R. (1998)
Nobel award stirs up debate on nitric oxide breakthrough.
Nature 395, 625-626.
9 October 1998.
2 October 1998.
- Chen, Z. and Banerjee, R. (1998)
Purification of soluble cytochrome b5 as a component of the
reductive activation of porcine methionine synthase.
J. Biol. Chem. 273, 26248-26255.
25 September 1998.
- Peterson, J.A. and Graham, S.E. (1998)
A close family resemblance: the importance of structure in understanding
Structure 6, 1079-1085.
18 September 1998.
11 September 1998.
A good bit of theoretical P450-logy from JACS:
Roitberg, A.E., Holden, M.J., Mayhew, M.P., Kurnikov, I.V., Beratan, D.L. and
Vilker, V.L. (1998)
Binding and electron transfer between putidaredoxin and cytochrome P450cam.
Theory and experiments.
J. Am. Chem. Soc. 120, 8927-8932.
Harris, D.L. and Loew, G.H. (1998)
Theoretical investigation of the proton assisted pathway to
formation of cytochrome P450 compound I.
J. Am. Chem. Soc. 120, 8941-8948.
4 September 1998.
Banci, L., Bertini, I., Cavazza, C., Felli, I.C. and Koulougliotis, D.
Probing the backbone dynamics of oxidized and reduced rat microsomal cytochrome
b5 via 15N rotating frame NMR relaxation
measurements: Biological implications.
Biochemistry 37, 12320-12330.
28 August 1998.
Perret, A. and Pompon, D. (1998)
Electron shuttle between membrane-bound cytochrome P450 3A4 and
b5 rules uncoupling mechanisms.
Biochemistry 37, 11412-11424.
14 August 1998.
Toy, P.H., Newcomb, M. and Hollenberg, P.F. (1998)
Hypersensitive mechanistic probe studies of cytochrome P450-catalyzed
hydroxylation reactions. Implications for the cationic pathway.
J. Am. Chem. Soc. 120, 7719-7729.
7 August 1998.
Lehnerer, M., Schulze, J., Pernecky, S.J., Lewis, D.F.V., Eulitz, M. and
Hlavica P. (1998)
Influence of mutation of the amino-terminal signal anchor sequence of
cytochrome P450 2B4 on the enzyme structure and electron transfer processes.
J. Biochem. (Tokyo) 124, 396-403.
31 July 1998.
24 July 1998.
This paper appears in a special issue
(Current Opinion in Chemical Biology, vol. 2, no. 2)
on Bio-inorganic Chemistry.
17 July 1998.
Siddhanta, U., Presta, A., Fan, B., Wolan, D., Rousseau, D.L. and Stuehr, D.J.
Domain swapping in inducible nitric-oxide synthase. Electron transfer occurs
between flavin and heme groups located on adjacent subunits in the dimer.
J. Biol. Chem. 273, 18950-18958.
10 July 1998.
Druhan, L.J. and Swenson, R.P. (1998)
Role of methionine 56 in the control of the oxidation-reduction potentials of
the Clostridium beijerinckii flavodoxin: Effects of substitutions by
aliphatic amino acids and evidence for a role of sulfur-flavin interactions.
Biochemistry 37, 9668-9678.
3 July 1998.
- Vidakovic, M., Sligar, S.G., Li, H. and Poulos, T.L. (1998)
Understanding the role of the essential Asp251 in cytochrome P450cam using
site-directed mutagenesis, crystallography, and kinetic solvent isotope
Biochemistry 37, 9211-9219.
26 June 1998.
A soluble P450cam/P450 2C9 chimera is constructed and is functional in a
putidaredoxin/putidaredoxin reductase system.
- Shimoji, M., Yin, H., Higgins, L. and Jones, J.P. (1998)
Design of a novel P450: A functional bacterial-human cytochrome
Biochemistry 37, 8848-8852.
19 June 1998.
Shikama, K. (1998)
The molecular mechanism of autoxidation for myoglobin and hemoglobin:
A venerable puzzle.
Chem. Rev. 98, 1357-1374.
12 June 1998.
- Meyer, K., Shirley, A.M., Cusumano, J.C., Bell-Lelong, D.A. and Chapple, C.
Lignin monomer composition is determined by the expression of a cytochrome
P450-dependent monooxygenase in Arabidopsis.
Proc. Natl. Acad. Sci. USA 95, 6619-6623.
5 June 1998.
Authors show that aldosterone is formed by P45011ß from
deoxycorticosterone via corticosterone, not via
18-hydroxydeoxycorticosterone; the intermediate metabolites do not
dissociate from the enzyme.
Imai, T., Yamazaki, T. and Kominami, S. (1998)
Kinetic studies on bovine cytochrome P45011ß catalyzing
successive reactions from deoxycorticosterone to aldosterone.
Biochemistry 37, 8097-8104.
29 May 1998.
Lee-Robichaud, P., Akhtar, M.E. and Akhtar, M. (1998)
Control of androgen biosynthesis in the human through the interaction of
Arg347 and Arg358 of CYP17 with cytochrome
Biochem. J. 332, 293-296.
22 May 1998.
Ueyama, N., Nishikawa, N., Yamada, Y., Okamura, T., Oka, S., Sakurai, H. and
Nakamura, A. (1998)
Synthesis and properties of octaethylporphinato(arenethiolato)iron(III)
complexes with intramolecular NH···S hydrogen bond:
Chemical function of the hydrogen bond.
Inorg. Chem. 37, 2415-2421.
15 May 1998.
Higgins, L., Bennett, G.A., Shimoji, M. and Jones, J.P. (1998)
Evaluation of cytochrome P450 mechanism and kinetics using kinetic deuterium
Biochemistry 37, 7039-7046.
8 May 1998.
Lvov, Yu.M., Lu, Z., Schenkman, J.B., Zu, X. and Rusling, J.F. (1998)
Direct electrochemistry of myoglobin and cytochrome P450cam in
alternate layer-by-layer films with DNA and other polyions.
J. Am. Chem. Soc. 120, 4073-4080.
1 May 1998.
24 April 1998.
Tschirret-Guth, R.A., Hui Bon Hoa, G. and Ortiz de Montellano, P.R. (1998)
Pressure-induced deformation of the cytochrome P450cam active
J. Am. Chem. Soc. 120, 3590-3596.
17 April 1998.
Armengaud, J. and Timmis, K.N. (1998)
The reductase RedA2 of the multi-component dioxin dioxygenase system of
Sphingomonas sp. RW1 is related to class-I cytochrome
Eur. J. Biochem. 253, 437-444.
10 April 1998.
Vaz, A.D.N., McGinnity, D.F. and Coon, M.J. (1998)
Epoxidation of olefins by cytochrome P450: Evidence from site-specific
mutagenesis for hydroperoxo-iron as an electrophilic oxidant.
Proc. Natl. Acad. Sci. USA 95, 3555-3560.
3 April 1998.
Chin, K.-K. and Chang, S.-F. (1998)
The -104 G nucleotide of the human CYP21 gene is important for
CYP21 transcription activity and protein interaction.
Nucleic Acids Res. 26, 1959-1964.
27 March 1998.
Cane, D.E. and Graziani, E.I. (1998)
Methymycin biosynthesis. Isolation of P450 monooxygenase activity in a
cell-free system from Streptomyces venezuelae.
J. Am. Chem. Soc. 120, 2682-2683.
20 March 1998.
Xia, B., Volkman, B.F. and Markley, J.L. (1998)
Evidence for oxidation-state-dependent conformational changes in
human ferredoxin from multinuclear, multidimensional NMR spectroscopy.
Biochemistry 37, 3965-3973.
13 March 1998.
Honkakoski, P. and Negishi, M. (1998)
Protein serine/threonine phosphatase inhibitors suppress
phenobarbital-induced Cyp2b10 gene transcription in mouse primary
Biochem. J. 330, 889-895.
6 March 1998.
Tavares, P., Pereira, A.S., Krebs, C., Ravi, N., Moura, J.J.G., Moura, I. and
Huynh, B.H. (1998)
Spectroscopic characterization of a novel tetranuclear Fe cluster in an
iron-sulfur protein isolated from Desulfovibrio desulfuricans.
Biochemistry 37, 2830-2842.
27 February 1998.
Shaik, S., Filatov, M., Schröder, D. and Schwarz, H. (1998)
Electronic structure makes a difference: Cytochrome P-450 mediated
hydroxylations of hydrocarbons as a two-state reactivity paradigm.
Chem. Eur. J. 4, 193-199.
20 February 1998.
Venkateswarlu, K., Lamb, D.C., Kelly, D.E., Manning, N.J. and Kelly, S.L.
The N-terminal membrane domain of yeast NADPH-cytochrome P450 (CYP)
oxidoreductase is not required for catalytic activity in sterol biosynthesis
or in reconstitution of CYP activity.
J. Biol. Chem. 273, 4492-4496.
13 February 1998.
Rivera, M., Seetharaman, R., Girdhar, D., Wirtz, M., Zhang, X., Wang, X. and
White, S. (1998)
The reduction potential of cytochrome b5 is modulated by
its exposed heme edge.
Biochemistry 37, 1485-1494.
6 February 1998.
Iametti, S., Uhlmann, H., Ragg, E., Sala, N., Grinberg, A., Beckert, V.,
Bernhardt, R. and Bonomi, F. (1998)
Cluster-iron substitution is related to structural and functional
features of adrenodoxin mutants and to their redox states.
Eur. J. Biochem. 251, 673-681.
30 January 1998.
Anandatheerthavarada, H.K., Addya, S., Mullick, J. and Avadhani, N.G.
Interaction of adrenodoxin with P4501A1 and its truncated form P450MT2 through
different domains: Differential modulation of enzyme activities.
Biochemistry 37, 1150-1160.
23 January 1998.
Sopková-de Oliveira Santos, J., Smith, J.C., Delaforge, M.,
Virelizier, H. and Jankowski, C.K. (1998)
Oxidation of tetrahydro-ß-carboline by cytochrome
P-450cam. Determination and rationalisation of product
Eur. J. Biochem. 251, 398-404.
16 January 1998.
Kisselev, P., Wessel, R., Pisch, S., Bornscheuer, U., Schmid, R.-D. and
Schwarz, D. (1998)
Branched phosphatidylcholines stimulate activity of cytochrome P450SCC
(CYP11A1) in phospholipid vesicles by enhancing cholesterol binding, membrane
incorporation, and protein exchange.
J. Biol. Chem. 273, 1380-1386.
9 January 1998.
2 January 1998.
Oinonen, T. and Lindros, K.O. (1998)
Zonation of hepatic cytochrome P-450 expression and regulation.
Biochem. J. 329, 17-35.
Kirill's P450 Café
Kirill's P450 Café - 2000
Kirill's P450 Café - 1999
Kirill's P450 Café - 1997
Kirill's Paper of the Week
Kirill's Review of the Week
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