Archive of Kirill's P450 Café - 2008

by Kirill Degtyarenko

Last modified: Fri Jul 18 15:53:40 BST 2008

11 July 2008.

• Chang, Z., Li, L., Pan, Z. and Wang, X. (2008) Crystallization and preliminary X-ray analysis of allene oxide synthase, cytochrome P450 CYP74A2, from Parthenium argentatum. Acta Crystallogr. F64, 668-670.

4 July 2008.

• Evans, J.P., Niemevz, F., Buldain, G. and Ortiz de Montellano, P.R. (2008) Isoporphyrin intermediate in heme oxygenase catalysis: oxidation of α-meso-phenylheme. J. Biol. Chem. 283, 19530-19539.

27 June 2008.

• Ouyang, B., Pochapsky, S.S., Dang, M. and Pochapsky, T.C. (2008) A functional proline switch in cytochrome P450_cam. Structure 16, 916-923.

20 June 2008.

• McCoy, J.G., Johnson, H..D, Singh, S., Bingman, C.A., Lei, I.-K., Thorson, J.S. and Phillips, G.N., Jr. (2008) Structural characterization of CalO2: A putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway. Proteins, in press.

13 June 2008.

• Ma, Q. and Lu, A.Y. (2008) The challenges of dealing with promiscuous drug-metabolizing enzymes, receptors and transporters. Curr. Drug Metab. 9, 374-383.

6 June 2008.

• Pechurskaya, T.A., Lukashevich, O.P., Gilep, A.A. and Usanov, S.A. (2008) Engineering, expression, and purification of "soluble" human cytochrome P45017 and its functional characterization. Biochemistry (Moscow), in press.

30 May 2008.

• Zawaira, A., Matimba, A. and Masimirembwa C. (2008) Prediction of sites under adaptive evolution in cytochrome P450 sequences and their relationship to substrate recognition sites. Pharmacogenetics & Genomics 18, 467-476.

23 May 2008.

• Miller, W.L. (2008) Steroidogenic enzymes. Endocr. Dev. 13, 1-18.

16 May 2008.

• Giron, M.C., Portolan, S., Bin, A., Mazzi, U. and Cutler, C.S. (2008) Cytochrome P450 and radiopharmaceutical metabolism. Q. J. Nucl. Med. Mol. Imaging , in press.

2 May 2008.

• White, M.A., Mast, N., Bjorkhem, I., Johnson, E.F., Stout, C.D. and Pikuleva, I.A. (2008) Use of complementary cation and anion heavy-atom salt derivatives to solve the structure of cytochrome P450 46A1. Acta Crystallogr. D64, 487-495.

25 April 2008.

• Salerno, J.C. (2008) Neuronal nitric oxide synthase: Prototype for pulsed enzymology. FEBS Lett. 582, 1395-1399.

18 April 2008.

Control of aggressiveness by social regulation of cytochrome P450s?

• Wang, L., Dankert, H., Perona, P. and Anderson, D.J. (2008) A common genetic target for environmental and heritable influences on aggressiveness in Drosophila. Proc. Natl. Acad. Sci. USA 105, 5657-5663.

11 April 2008.

• Ewen, K.M., Schiffler, B., Uhlmann-Schiffler, H., Bernhardt, R. and Hannemann, F. (2008) The endogenous adrenodoxin reductase-like flavoprotein arh1 supports heterologous cytochrome P450-dependent substrate conversions in Schizosaccharomyces pombe. FEMS Yeast Res. 8, 432-441.

28 March 2008.

• Adams, J.S., Chen, H., Chun, R., Ren, S., Wu, S., Gacad, M., Nguyen, L., Ride, J., Liu, P., Modlin, R. and Hewison, M. (2007) Substrate and enzyme trafficking as a means of regulating 1,25-dihydroxyvitamin D synthesis and action: the human innate immune response. J. Bone Miner. Res. 22, Suppl. 2, V20-V24.

21 March 2008.

• Aliverti, A., Pandini, V., Pennati, A., de Rosa, M. and Zanetti, G. (2008) Structural and functional diversity of ferredoxin-NADP⁺ reductases. Arch. Biochem. Biophys., in press.

14 March 2008.

• Manna, S.K. and Mazumdar, S. (2008) Reversible inactivation of cytochrome P450 by alkaline earth metal ions: Auxiliary metal ion induced conformation change and formation of inactive P420 species in CYP101. J. Inorg. Biochem. 102, 1312-1321.

7 March 2008.

• Sugimoto, H., Shinkyo, R., Hayashi, K., Yoneda, S., Yamada, M., Kamakura, M., Ikushiro, S.I., Shiro, Y. and Sakaki, T. (2008) Crystal structure of CYP105A1 (P450SU-1) in complex with 1α,25-dihydroxyvitamin D₃. Biochemistry 47, 4017-4027.

29 February 2008.

• Maghzal, G.J., Thomas, S.R., Hunt, N.H. and Stocker, R. (2008) Cytochrome b₅, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells. J. Biol. Chem. 283, 12014-12025.

22 February 2008.

• Brown, C.M., Reisfeld, B. and Mayeno, A.N. (2008) Cytochromes P450: a structure-based summary of biotransformations using representative substrates. Drug Metab. Rev. 40, 1-100.

8 February 2008.

• Kimura, I., Nakayama, Y., Yamauchi, H., Konishi, M., Miyake, A., Mori, M., Ohta, M., Itoh, N. and Fujimoto, M. (2008) Neurotrophic activity of neudesin, a novel extracellular heme-binding protein, is dependent on the binding of heme to its cytochrome b₅-like heme/steroid-binding domain. J. Biol. Chem. 283, 4323-4331.

1 February 2008.

• Gleeson, M.P. (2008) Generation of a set of simple, interpretable ADMET rules of thumb. J. Med. Chem. 51, 817-834.

25 January 2008.

• Gonzalez-Kristeller, D.C., Farage, L., Fiorini, L.C., Loomis, W.F. and da Silva, A.M. (2008) The P450 oxidoreductase, RedA, controls development beyond the mound stage in Dictyostelium discoideum. BMC Dev. Biol. 8, 8.

18 January 2008.

• Ho, W.W., Li, H., Nishida, C.R., Ortiz de Montellano, P.R. and Poulos, T.L. (2008) Crystal structure and properties of CYP231A2 from the thermoacidophilic archaeon Picrophilus torridus. Biochemistry 47, 2071-2079.

11 January 2008.

• Rontein, D., Onillon, S., Herbette, G., Lesot, A., Werck-Reichhart, D., Sallaud, C. and Tissier, A. (2008) CYP725A4 from yew catalyzes complex structural rearrangment of taxa-4(5)-11(12)-diene into the cyclic ether 5(12)-oxa-3(11)-cyclotaxane. J. Biol. Chem. 283, 6067-6075.

4 January 2008.

• Newcomb, M., Halgrimson, J.A., Horner, J.H., Wasinger, E.C., Chen, L.X. and Sligar, S.G. (2008) X-ray absorption spectroscopic characterization of a cytochrome P450 compound II derivative. Proc. Natl. Acad. Sci. USA, in press.

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