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This page was last modified Feb. 14, 2003. 

Plant P450s that have appeared since the 1993 P450 nomenclature update.
Part D of the bibilographic P450 documents.  These files were broken into 
      five parts to reduce the download time for each part. 
      This includes references that were incomplete and duplications
      of sequences that were already in the update.  If a sequence 
      is assigned an accession number that was not in the old update
      it is included in this list.  Some expressed sequence tags (ESTs)
      are also included from Arabidopsis thaliana and Catharanthus roseus.
      This list was last modified August 29, 2001. (added 76J1 
      sequence to this file.  This is not in Genbank)

Plant P450 families are numbered CYP51, CYP71 to CYP99.  The numbers then jump to 
      701-726, because there are 51 plant P450 families.  Many of the 
      sequences included here are PCR fragments or expressed sequence tags
      that are quite short.  These fragments have not been
      assigned to families, unless a clear family resemblance was present.
      CYP51 is the only family conserved enough to be identified as the
      same family across kingdoms, including plants, fungi, animals and 
      bacteria.
      In the Arabidopsis expressed sequence tags, some are from the C-
      terminal and some are from the N-terminal or middle region of the
      P450s.Clearly some are from the same sequence, but the relationship
      cannot be known until the whole sequence is complete, or 
      until PCR primers from the fragments can be used to identify
      which fragments are in the same sequence.

Note: at least one plant sequence has been reported that shows a P450 spectrum and 
P450 activity, but the sequence does not appear to be a P450 family member based on 
descent from a common ancestor. (GenEMBL D64052, tobacco, Biochim. Biophys. Acta 
1308, 231-240 1996)  This sequence when blastn searched shows highest similarity to 
rRNA.  

BLASTN-outcome:D64052     Tobacco mRNA for cytochrome P450 like seq. 10050  0.0   
   1emb|Z11498|MSRRN26S   M.sativa 26S rRNA                                     1034  4.5e-311

So D64052 is not a P450 but a ribosomal RNA.
Nitric oxide synthases have a heme thiolate spectrum.  A heme thiolate ligand is 
not restricted to P450 family members.  It is ironic that the name cytochrome P450 
derives from a characteristic spectrum, but not all proteins with this spectrum can 
be included in the family of cytochrome P450s.  This family is now defined by 
sequence, and not spectral properties.

Note: First 71D sequences are in GenBank 71D6 and 71D7 (see below)

51 Family

71A Subfamily

71B Subfamily

71C Subfamily

71D Subfamily

71E Subfamily

72A Subfamily

72B Subfamily

73A Subfamily

74A Subfamily

74B Subfamily

75A Subfamily

76A Subfamily

76B Subfamily

76C Subfamily

76D Subfamily

77A Subfamily

78A Subfamily

79A Subfamily

79B Subfamily

79C Subfamily

79D Subfamily

79E Subfamily

80A Subfamily

80B Subfamily

81A Subfamily

81B Subfamily

81C Subfamily

81D Subfamily

81E Subfamily

81F Subfamily

81G Subfamily

81H Subfamily

82A Subfamily

82B Subfamily

82C Subfamily

82D Subfamily

82E Subfamily

82F Subfamily

83A Subfamily

83B Subfamily

83C Subfamily

83D Subfamily

84A Subfamily

85A Subfamily

86A Subfamily

87A Subfamily

88A Subfamily

89A Subfamily

90A Subfamily

90B Subfamily

91A Subfamily

92A Subfamily

92B Subfamily

93A Subfamily

93B Subfamily

93C Subfamily

93D Subfamily

94A Subfamily

95A Subfamily

96A Subfamily

96B Subfamily

97A Subfamily

97B Subfamily

98A Subfamily

99A Subfamily

701A Subfamily

702A Subfamily

703A Subfamily

704A Subfamily

705A Subfamily

706A Subfamily

707A Subfamily

708A Subfamily

709A Subfamily

709B Subfamily

710A Subfamily

711A Subfamily

712A Subfamily

713A Subfamily

714A Subfamily

715A Subfamily

716A Subfamily

716A Subfamily

716A Subfamily


51 Family

CYP51       Sorghum bicolor
            GenEMBL U74319
            Bak,S., Kahn,R.A., Olsen,C.E. and Halkier,B.A. 
            Cloning and expression in Escherichia coli of the obtusifoliol 14
            alpha-demethylase of Sorghum bicolor (L.) Moench, a cytochrome P450 
            orthologous to the sterol 14 alpha-demethylases (CYP51) from fungi and mammals
            Plant J. 11 (2), 191-201 (1997).

CYP51       Triticum aestivum (wheat)
            GenEMBL Y09291 (1655bp)
            Cabello-Hurtado F, Taton M, Forthoffer N, Kahn R, Bak S, Rahier A,    
            Werck-Reichhart D
            Optimized expression and catalytic properties of a wheat obtusifoliol
            14alpha-demethylase (CYP51) expressed in yeast Complementation
            of erg11Delta yeast mutants by plant CYP51.
            Eur J Biochem  262,435-446 1999 

CYP51       Triticum aestivum (wheat)
            GenEMBL Y09292 (1231bp)
            Cabello-Hurtado F, Taton M, Forthoffer N, Kahn R, Bak S, Rahier A, 
            Werck-Reichhart D
            Optimized expression and catalytic properties of a wheat obtusifoliol
            14alpha-demethylase (CYP51) expressed in yeast Complementation
            of erg11Delta yeast mutants by plant CYP51.
            Eur J Biochem  262,435-446 1999 

CYP51A1     Arabidopsis thaliana
            GenEMBL AC002329 Complete sequence
            GenEMBL AC007127 comp(82241-84323) complete seq.
            Contig 1783 of the TIGR Landsberg erecta sequences has 99% match

CYP51A2     Arabidopsis thaliana
            GenEMBL AC007296 comp(52507-54167) 
            GenEMBL N65031 (EST fragment)
            GenEMBL AA651059 (EST fragment) opposite end AA720360
            These ESTs are similar but not identical to CYP51A1.
            76% to CYP51A1

CYP51       Zea mays
            GenEMBL T12664 (EST fragment)

CYP51       Oryza sativa (rice)
            GenEMBL    AB025047
            Aoyama,Y., Horiuchi,T. and Yoshida,Y.
            Cloning and characterization of rice sterol 14-demethylase (CYP51) gene.
            Unpublished

CYP51       Pinus taeda (pine)
            GenEMBL BF517195.1 AW984874.1 AW626637.1 C-term fragments
            BF610290.1 CYP51 N-term
MDFIQNIYVQAGLLILATLVLAKIVSSILGFGSSKNLPPMVPAWPIVGGLMKFLKGPIVMLR
EEYPKLGNVFTIKLLIKNVTFLIGPEVSQHFFKXPESDL
CYP51 C-term
LXHDVLAXXDVLYRCIKEALRLHPPLIVLLRSNHRDFTVTAKDGKDYVIPKGHVVATSPAFANRLPHIFKNPDT
YDPDRFVPGREEDKVGGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFELELISP
FPEIDWNAMVVGVKDKVMVRYRRRPLSVD*
      
71A Subfamily

CYP71A1     Persea americana (avocado)
            PIR A44973 (40 amino acids)
            GenEMBL M32855
            O'Keefe, D.P. and Leto, K.J.
            Cytochrome P-450 from the mesocarp of avocado (Persea
            americana).
            Plant Physiol. 89, 1141-1149 (1989)

CYP71A2     Solanum melongena cv. Sinsadoharanasu (eggplant)
            GenEMBL D14990 (1744bp) X71654 (1747bp) 
            Swiss P37118 (505 amino acids) PIR S36806 (505 amino acids)
            Umemoto,N., Kobayashi,O., Ishizaki-Nishizawa,O. and Toguri,T.
            cDNAs sequences encoding cytochrome P450 (CYP71 family) from
            eggplant seedlings.
            FEBS Lett. 330, 169-173 (1993)
            Note: clone name 154 also called CYPEG4

CYP71A3     Solanum melongena cv. Sinsadoharanasu (eggplant)
            GenEMBL X70982 (1096bp) Swiss P37119 (365 amino acids)
            PIR S36807 (365 amino acids)
            Umemoto,N., Kobayashi,O., Ishizaki-Nishizawa,O. and Toguri,T.
            cDNAs sequences encoding cytochrome P450 (CYP71 family) from
            eggplant seedlings.
            FEBS Lett. 330, 169-173 (1993)
            Note: clone name F151 also called CYPEG3

CYP71A4     Solanum melongena cv. Sinsadoharanasu (eggplant)
            GenEMBL X70981 (1724bp) Swiss P37117 (507 amino acids)
            PIR S36805 (507 amino acids)
            Umemoto,N., Kobayashi,O., Ishizaki-Nishizawa,O. and Toguri,T.
            cDNAs sequences encoding cytochrome P450 (CYP71 family) from
            eggplant seedlings.
            FEBS Lett. 330, 169-173 (1993)
            Note: clone name E138 also called CYPEG2
            Incorrectly called CYP71A1 in Genbank entry

CYP71A5v1   Nepeta racemosa (catmint, source of catnip)
            GenEMBL Y09423(1703bp)
            Clark, I.M., Forde, B.G. and Hallahan, D.L.
            Spatially distinct expression of two new cytochrome P450s in leaves
            of Nepeta racemosa: identification of a trichome-specific isoform.
            Plant Mol. Biol. 33, 875-885 (1997)
            note: sequence is revised from original submission on 9/10/98

CYP71A5v2     Nepeta racemosa (catmint, source of catnip)
            GenEMBL 
            Clark, I.M., Forde, B.G. and Hallahan, D.L.
            Spatially distinct expression of two new cytochrome P450s in leaves
            of Nepeta racemosa: identification of a trichome-specific isoform.
            Plant Mol. Biol. 33, 875-885 (1997)
            note: a second allele

CYP71A6     Nepeta racemosa (catmint, source of catnip)
            GenEMBL Y09424(1697bp)
            Clark, I.M., Forde, B.G. and Hallahan, D.L.
            Spatially distinct expression of two new cytochrome P450s in leaves
            of Nepeta racemosa: identification of a trichome-specific isoform.
            Plant Mol. Biol. 33, 875-885 (1997)

CYP71A7     Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69779 (346bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 7 from Fig. 2.

CYP71A8     Mentha piperita
            GenEMBL Z33875 (2141bp)
            Kang,M.H. and Choi,Y.D.
            Molecular cloning of a genomic DNA for cytochrome P-450 oxidase
            from Mentha piperita.
            unpublished (1994)

CYP71A9     Glycine max (soybean)
            GenEMBL Y10489 (1603bp)
            Schopfer,C.R. and Ebel,J.
            Identification of elicitor-induced cytochrome P450s of soybean
            (Glycine max L.) using differential display of mRNA
            Mol. Gen. Genet. 258, 315-322 (1998)
            clone CP1

CYP71A10    Glycine max (soybean)
            GenEMBL AF022157 (1838bp)
            Siminszky,B., Dewey,R.E. and Corbin,F.T.
            capable of catalyzing the metabolism of phenylurea herbicides

CYP71A11X   tobacco
            no accession number 
            Takashi Yamada
            tobacco sequence 2
            submitted to nomenclature committee 9/9/97
            renamed CYP71AH1 only 46% to 71B38

CYP71A12    Arabidopsis thaliana
            GenEMBL AC002340
            T11J7.14

CYP71A13    Arabidopsis thaliana
            GenEMBL AC002340
            T11J7.16 
            ESTs H76866, AA605540

CYP71A14      Arabidopsis thaliana
            GenEMBL AF069716 10000-14000 region
            GenEMBL AC005964 comp(3688-6807)
            67% identical to CYP71A13
            no ESTs 

CYP71A15      Arabidopsis thaliana
            GenEMBL AF069716 16000-19000 region
            GenEMBL AC005964 comp(1066-1380) partial seq.
            no ESTs

CYP71A16      Arabidopsis thaliana
            GenEMBL AB022210 comp(26631-24211)
            64% identical to 71A14 ESTs AA395422, T43806

CYP71A17P    Arabidopsis thaliana
           GenEMBL AB017065 comp(19000-21000 region)
           64% identical to 71A14 
           clear pseudogene, missing large regions including I-helix

CYP71A18     Arabidopsis thaliana
            GenEMBL AC007296 83847-85677 
            86% identical to 71A12 
            no ESTs no GSSs

CYP71A19        Arabidopsis thaliana
           GenEMBL AL049608 
           join(11443..11829,12066..12542,12626..12907,13106..13432)
          gene T9E8.30 64% identical to 71A16 no ESTs no GSSs

CYP71A20        Arabidopsis thaliana
           GenEMBL AL049608 
           join(21221..21598,21753..22253,22331..22612,23485..23811)
          gene T9E8.50 88% identical to CYP71A19 no ESTs no GSSs

CYP71A21        Arabidopsis thaliana
           GenEMBL AL049659 comp(61576..62187,62279..63139) 
           gene T29H11.160
           also U31288 fragment at end of another gene and GSS B25921 no ESTs

CYP71A22        Arabidopsis thaliana
           GenEMBL AL049659 comp (64631..65242,65328..66188) 
           gene T29H11.170 EST N38590

CYP71A23        Arabidopsis thaliana
           GenEMBL AL049659 comp (67262..67861,68005..68856) 
           gene T29H11.180

CYP71A24        Arabidopsis thaliana
           GenEMBL AL049659 comp(70246..71784) 
           gene T29H11.190 
           Genbank translation has a retained intron before the I-helix

CYP71A25        Arabidopsis thaliana
           GenEMBL AL049659 comp (73216..73830,73929..74786) 
           gene T29H11.200
           ESTs T22148, AA395671, AI100632

CYP71A26    Arabidopsis thaliana
            GenEMBL AL049659 comp(76207..76818,76952..77809) 
            T29H11.210

CYP71A27    Arabidopsis thaliana
            GenEMBL AL022224
            F1C12.160a  (parts from two genes are represented as one gene) 
            this is the first gene
            61% identical to CYP71A20
            note formerly 713A1

CYP71A28    Arabidopsis thaliana
            GenEMBL AL022224
            F1C12.160b  (parts from two genes are represented as one gene)
            this is the second gene 
            60% identical to CYP71A20
            note formerly 713A2

71B Subfamily

CYP71B1     Thlaspi arvense
            GenEMBL L24438 (1648bp)
            Udvardi,M.K., Metzger,J.D., Krishnapillai,V., Peacock,W.J. and
            Dennis,E.S.
            Cloning and nucleotide sequence of a full length cDNA from Thlaspi arvense
            that encodes a cytochrome P-450.
            Plant Physiol. 104, 755-756 (1994)

CYP71B2     Arabidopsis thaliana
            D78605 (502 amino acids) also AC007357 31915-33510
            Mizutani,M., Ward,E. and Ohta,D.
            Cytochrome p450 superfamily in Arabidopsis thaliana: isolation of
            cDNAs, differential expression, and RFLP mapping of multiple
            cytochromes P450
            Plant Mol. Biol. 37, 39-52 (1998)
            P450-48 nearly identical to Z18072 and Z35218 ESTs

CYP71B3     Arabidopsis thaliana
            D78602 (501 amino acids) also AB024038 COMP(43851-45465)
            Mizutani,M., Ward,E. and Ohta,D.
            Cytochrome p450 superfamily in Arabidopsis thaliana: isolation of
            cDNAs, differential expression, and RFLP mapping of multiple
            cytochromes P450
            Plant Mol. Biol. 37, 39-52 (1998)
            P450-13-1
            Contig 885 of the TIGR Landsberg erecta sequences has 100% match

CYP71B4     Arabidopsis thaliana
            D78603 (504 amino acids) also AB024038 comp(78016-79595)
            Mizutani,M., Ward,E. and Ohta,D.
            Cytochrome p450 superfamily in Arabidopsis thaliana: isolation of
            cDNAs, differential expression, and RFLP mapping of multiple
            cytochromes P450
            Plant Mol. Biol. 37, 39-52 (1998)
            P450-13-6
            same as EST T21833, AI100749 GSSs B12539, B10642

CYP71B5     Arabidopsis thaliana
            D78601 (498 amino acids) also AL132958
            Mizutani,M., Ward,E. and Ohta,D.
            Cytochrome p450 superfamily in Arabidopsis thaliana: isolation of
            cDNAs, differential expression, and RFLP mapping of multiple
            cytochromes P450
            Plant Mol. Biol. 37, 39-52 (1998)
            P450-12

CYP71B6     Arabidopsis thaliana
            D78604 (503 amino acids)
            Mizutani,M., Ward,E. and Ohta,D.
            Cytochrome p450 superfamily in Arabidopsis thaliana: isolation of
            cDNAs, differential expression, and RFLP mapping of multiple
            cytochromes P450
            Plant Mol. Biol. 37, 39-52 (1998)
            ESTs F15479, F14179
            P450-23
            identical to AC005967

CYP71B7      Arabidopsis thaliana
            GenEMBL X97864 (1684bp) also AC007357 33975-41560
            Maughan.J.A., Nugent, J.H.A. and Hallahan, D.L.
            expression of CYP71B7 a cytochrome P450 expressed sequence tag
            from Arabidopsis thaliana.
            unpublished (1996)
            full length sequence of 5 ESTs R65111, T44310, T04541, T04814, T44875
            Contig 610 of the TIGR Landsberg erecta sequences has 100% match

CYP71B8       Arabidopsis thaliana
            GenEMBL AB011485 27121-28820

CYP71B9      Arabidopsis thaliana
            GenEMBL AC004136
            47% identical to 71B7
            no ESTs

CYP71B10       Arabidopsis thaliana
            GenEMBL AB019233 comp(24311 - 22750)
            71% identical to AC004136
            no ESTs no GSS (1/13/99)

CYP71B11 Arabidopsis thaliana
            GenEMBL AC006259 (94-702) partial seq.
            GenEMBL AC005964 (66557-68105) whole seq.
            BAC F21J6 from chromosome V mapping near 60.5 cM
            69% identical to 71B1
            ESTs Z33963, Z33677 GSSs B28673, B78204 and AQ011301

CYP71B12 Arabidopsis thaliana
            GenEMBL AC006259 (4286-6376)
            GenEMBL AC005964 (72227-73777)
            BAC F21J6 from chromosome V mapping near 60.5 cM
            92% identical to 71B11

CYP71B13 Arabidopsis thaliana
            GenEMBL AC006259 (9294-10829)
            GenEMBL AC005964 (76695-78230)
            BAC F21J6 from chromosome V mapping near 60.5 cM
            70% identical to 71B1

CYP71B14 Arabidopsis thaliana
            GenEMBL AC006259 comp(30932-32475)
            BAC F21J6 from chromosome V mapping near 60.5 cM
            68% identical to 71B1

CYP71B15       Arabidopsis thaliana
           GenEMBL AB016889 (54457-56024)
           62% identical to 71B7

CYP71B16         Arabidopsis thaliana
            GenEMBL AB024038 comp(13279-14849)
            84% identical to CYP71B17
            no ESTs no GSSs

CYP71B17         Arabidopsis thaliana
            GenEMBL AB024038 comp(15932-17496)
            84% identical to CYP71B17
            no ESTs no GSSs

CYP71B18         Arabidopsis thaliana
            GenEMBL AB024038 comp(18098-19609)
            80% identical to CYP71B17 
            ESTs AA650762, T44224, AI099821 (2 diffs)
            T44855 (3 diffs) GSS B25335
            missing an internal 21 amino acid fragment and frame shift after 
            first 6 N-terminal  amino acids. may be a pseudogene

CYP71B19         Arabidopsis thaliana
            GenEMBL AB024038 comp(21194-22760)
            ESTs H76241
            60% identical to 71B2

CYP71B20         Arabidopsis thaliana
            GenEMBL AB024038 comp(26044-27630)
            94% identical to CYP71B19
            ESTs T04186, T45449, T21193, AA585920 (1 diff)
            T20987 (3 diffs) no GSSs

CYP71B21         Arabidopsis thaliana
            GenEMBL AB024038 comp(31112-32720)
            88% identical to 71B22 
            no ESTs no GSSs

CYP71B22         Arabidopsis thaliana
            GenEMBL AB024038 36984-38609
            88% identical to CYP71B21
            no ESTS no GSSs

CYP71B23         Arabidopsis thaliana
            GenEMBL AB024038 comp(40969-42839)
            71% ident to 71B7 
            no ESTs no GSSs

CYP71B24         Arabidopsis thaliana
            GenEMBL AB024038 comp(45837-47529)
            80% identical to 71B3 no ESTs 
            GSS AQ011201 (5 diffs/178 = 97%) B96063 4 diffs/126 = 97% these
            may be a related gene.

CYP71B25         Arabidopsis thaliana
            GenEMBL AB024038 comp(75254-76832)
            74% identical to 71B4 
            no ESTs no GSSs

CYP71B26         Arabidopsis thaliana
            GenEMBL AB024038 comp(80407-82076)
            68% identical to 71B9 
            very similar to Z33952, Z34037 (91% identical) but different gene

CYP71B27         Arabidopsis thaliana
             GenEMBL AB007357 28180-29804 
             GSSs B11396, B21019 no ESTs

CYP71B28         Arabidopsis thaliana
             GenEMBL AB007357 34549-36103 
             ESTs T20906, T76255, T14112, N65665, AI100027

CYP71B29         Arabidopsis thaliana
             GenEMBL AB007357 36686-38241 
             similar to GSS B21027

CYP71B30P    Arabidopsis thaliana
             GenEMBL AL132958
             Clone T04D02 from the EU Chr 3 project contains 71B5 and 3 new 71Bs 
             (71B30P, 71B31, 71B32) and 97C1 (formerly a confidential sequence)
             82204-83671 missing N-term 80 AA not found between end of 71B5 and start 
             of this sequence probably a pseudogene
             clone F4P12  from the EU Chr 3 project overlaps T04D02 and contains 
             two of the three new 71Bs and part of the third

CYP71B31     Arabidopsis thaliana
             GenEMBL AL132958
             Clone T04D02 from the EU Chr 3 project contains 71B5 and 3 new 71Bs 
             (71B30P, 71B31, 71B32) and 97C1 (formerly a confidential sequence)
             84593-86302 GSSs AL092788 (clone T10J6) AL081333 (clone F2M19) No ESTs
             clone F4P12  from the EU Chr 3 project overlaps T04D02 and contains 
             two of the three new 71Bs and part of the third

CYP71B32     Arabidopsis thaliana
             GenEMBL AL132958
             Clone T04D02 from the EU Chr 3 project contains 71B5 and 3 new 71Bs 
             (71B30P, 71B31, 71B32) and 97C1 (formerly a confidential sequence)
             87497-89156 two in frame stop codons may be a pseudogene
             clone F4P12  from the EU Chr 3 project overlaps T04D02 and contains 
             two of the three new 71Bs and part of the third

CYP71B33     Arabidopsis thaliana
             GenEMBL AP001298 comp(479-2126)

CYP71B34     Arabidopsis thaliana
             GenEMBL AP001298 comp(2977-4644)

CYP71B35     Arabidopsis thaliana 
             GenEMBL AP001298 comp(4867-6557)

CYP71B36     Arabidopsis thaliana
             GenEMBL AP001298 comp(8161-9842)

CYP71B37     Arabidopsis thaliana
             GenEMBL AP001298 comp(10654-12314)
             EST Z27299

71C Subfamily

CYP71C1     Zea mays (maize)
            GenEMBL X81827 (1890bp) X81828 (4352bp)
            Frey,M., Kliem,R., Saedler,H. and Gierl,A.
            Expression of a cytochrome P450 gene family in maize
            Mol. Gen. Genet. 246, 100-109 (1995)

CYP71C1     Zea mays
            GenEMBL AF004210 (1185bp)
            Sisco,P.H.
            agr(c94) random cDNA clone from Zea mays etiolated coleoptiles
            Unpublished

CYP71C2     Zea mays (maize)
            GenEMBL X81829 (1786bp) 
            Frey,M., Kliem,R., Saedler,H. and Gierl,A.
            Expression of a cytochrome P450 gene family in maize
            Mol. Gen. Genet. 246, 100-109 (1995)

CYP71C2v2   Zea mays
            Sharon Potter
            sequence b
            submitted to nomenclature committee

CYP71C2     Zea mays (maize)
            GenEMBL Y11404 (3130bp)
            Gierl, A.
            unpublished (1997)

CYP71C3     Zea mays (maize)
            GenEMBL X81830 (1800bp)
            Frey,M., Kliem,R., Saedler,H. and Gierl,A.
            Expression of a cytochrome P450 gene family in maize
            Mol. Gen. Genet. 246, 100-109 (1995)

CYP71C3     Zea mays (maize)
            GenEMBL Y11403 (5057bp)
            Gierl, A.
            unpublished (1997)

CYP71C3v2   Zea mays (maize)
            no accession number
            Persans,M. and Schuler,M.
            unpublished (1995)
            note:  Maize strain used in Schuler's lab = B73, Frey's lab used CI31A

CYP71C4     Zea mays (maize)
            GenEMBL X81831 (1878bp)
            Frey,M., Kliem,R., Saedler,H. and Gierl,A.
            Expression of a cytochrome P450 gene family in maize
            Mol. Gen. Genet. 246, 100-109 (1995)

CYP71C4     Zea mays (maize)
            GenEMBL Y11368 (7466bp)
            Gierl, A.
            unpublished (1997)

CYP71C5     Zea mays
            Sharon Potter
            sequence a
            submitted to nomenclature committee
            55% to 71C4

CYP71C6     Triticum aestivum (wheat)
            no accession number
            Daniele Werck
            submitted to nomenclature committee 1/20/99
            probable orthologue to CYP71C1 (79% identical)

CYP71C6     Triticum aestivum (wheat)
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 4/30/2000
            clone name N-2
            probable orthologue to CYP71C1 (79% identical)
            100% identical to 71C6 of Werck

CYP71C7v1   Triticum aestivum (wheat)
            no accession number
            Daniele Werck
            submitted to nomenclature committee 1/20/99
            probable orthologue to CYP71C2 (76% identical)

CYP71C7v2   Triticum aestivum (wheat)
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 4/30/2000
            clone name N-3
            probable orthologue to CYP71C2 (76% identical)
            96% identical to 71C7v1 of Werck

CYP71C8v1   Triticum aestivum (wheat)
            no accession number
            Daniele Werck
            submitted to nomenclature committee 1/20/99
            probable orthologue to CYP71C3 (78% identical)

CYP71C8v2   Triticum aestivum (wheat)
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 4/30/2000
            clone name N-4
            probable orthologue to CYP71C3 (78% identical)
            95% identical to 71C8v1 of Werck

CYP71C9v1   Triticum aestivum (wheat)
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 4/30/2000
            clone name N-5
            probable orthologue to CYP71C4 (78% identical)
            97% identical to 71C9v2

CYP71C9v2   Triticum aestivum (wheat)
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 4/30/2000
            clone name N-6
            probable orthologue to CYP71C4 (78% identical)
            97% identical to 71C9v1

CYP71C9v2   Triticum aestivum (wheat)
            No accession number
            Daniele Werck-Reichhart
            submitted to nomenclature committee July 23, 2001
            76% identical to 71C4
            clone C4-38
            100% identical to Dr. Imaishis sequence

CYP71C10    Triticum aestivum (wheat) formerly CYP71H1
            No accession number
            Daniele Werck-Reichhart 
            55% to 71C4 but only 50% to 71C8, 56% to 71C11
            clone name 71F8I2
            submitted to nomenclature committee July 18, 2000
            This sequence has been reassigned to the 71C subfamily
            It is on the outskirts of the subfamily, but new sequences 
            force it to belong there rather than in a new subfamily.

CYP71C11    Triticum aestivum (wheat)
            No accession number
            Daniele Werck-Reichhart
            submitted to nomenclature committee Jan 6, 2001
            58% identical to 71C7, 57% to 71C6 and 56% identical to 71C10

CYP71C-like Hordeum vulgare (barley)
            GenEMBL AJ000231
            Hess,W.R.
            Analysis of randomly selected cDNAs from white leaves of the
            albostrians mutant of barley
            Unpublished
      GQRMCPGMNLVNHFDWELPIGIESIDMTEVFGITIRRKEKLLLIPKSRL
            68% identical to C-terminal of 71C4

71D Subfamily

CYP71D1     Catharanthus roseus
            GenEMBL AY192573
            Schroeder,J.
            submitted to nomenclature committee

CYP71D2     Catharanthus roseus
            GenEMBL AY192574
            Schroeder,J.
            submitted to nomenclature committee

CYP71D3X    Arabidopsis thaliana
            GenEMBL Z27299
            62% amino acid identity to CYP71D1
            this short EST fragment belongs to 71B37

CYP71D4     Solanum tuberosum cv. Datura (potato)
            GenEMBL AJ296346
            Michel Schneider 
            56.1% identical to CYP71D1
            induced rapidly by Phytophthora infestans infection or wounding
            (pesonal communication from Michel Schneider)

CYP71D5    Nicotiana tabacum (tobacco)
           no accession number
           Simon Warner
           submitted to nomenclature committee

CYP71D6      Solanum chacoense (Chaco potato)
           GenEMBL U48434 (1641bp)
           Hutvagner, G., Barta, E. and Banfalvi, Z.
           Isolation and sequence analysis of a cDNA and related gene for 
           cytochrome P450 from Solanum chacoense.
           Gene 188 (2), 247-252 (1997)

CYP71D7    Solanum chacoense (Chaco potato)
           GenEMBL U48435 (3107bp)
           Hutvagner, G., Barta, E. and Banfalvi, Z.
           Isolation and sequence analysis of a cDNA and related gene for 
           cytochrome P450 from Solanum chacoense.
           Gene 188 (2), 247-252 (1997)

CYP71D8     Glycine max (soybean)
            GenEMBL Y10493 (1800bp)
            Schopfer,C.R. and Ebel,J.
            Identification of elicitor-induced cytochrome P450s of soybean
            (Glycine max L.) using differential display of mRNA
            Mol. Gen. Genet. 258, 315-322 (1998)
            clone CP7

CYP71D9     Glycine max (soybean)
            GenEMBL Y10490 (1754bp)
            Schopfer,C.R. and Ebel,J.
            Identification of elicitor-induced cytochrome P450s of soybean
            (Glycine max L.) using differential display of mRNA
            Mol. Gen. Genet. 258, 315-322 (1998)
            clone CP3

CYP71D10    Glycine max (soybean)
            GenEMBL AF022459 (1691bp)
            Siminszky,B., Dewey,R.E. and Corbin,F.T.
            clone name 5/16

CYP71D11    Lotus japonicus
            GenEMBL AF000403 (1641bp)
            Szczyglowski,K., Hamburger,D., Kapranov,P. and de Bruijn,F.J.
            Construction of a Lotus japonicus late nodulin expressed sequence
            tag library and identification of novel nodule-specific genes
            Plant Physiol. 114 (4), 1335-1346 (1997)

CYP71D12    Catharanthus roseus (Madagascar periwinkle)
            GenEMBL AJ238612 (1682 bp)
            Schroeder,G., Unterbusch,E., Kaltenbach,M., 
            Schmidt,J., Strack,D., De Luca,V., and Schroeder,J.:
            Light-induced cytochrome P450-dependent enzyme in 
            indole alkaloid biosynthesis: tabersonine 
            16-hydroxylase. 
            FEBS Lett. 458, 97-102 (1999)
            Note: due to a mistake on my part the name 71D12 was assigned
            to two sequences.  The sequence of Schroeder has priority
            Since it was submited and named earlier than Lupiens sequence.

CYP71D12X   Mentha spicata (spearmint) Renamed as CYP71D18
            GenEMBL AF124815
            Shari Lupien, Rodney Croteau
            Regio-Specific Cytochrome p450 Limonene Hydroxylases From Mint
            (mentha) Species
            unpublished
            submitted to nomenclature committee 1/24/99
            50% identical to 71D7, 69% identical to 71D13
            (-)4S-Limonene-6-Hydroxylase
            Note: due to a mistake on my part the name 71D12 was assigned
            to two sequences.  The sequence of Schroeder has priority
            Since it was submitted and named earlier than Lupiens sequence.

CYP71D13      Mentha X piperita (peppermint)
            GenEMBL AF124816
            Shari Lupien, Rodney Croteau
            Regio-Specific Cytochrome p450 Limonene Hydroxylases From Mint
            (mentha) Species
            unpublished
            submitted to nomenclature committee 1/24/99
            69% identical to 71D12
            (-)4S-Limonene-3-Hydroxylase
            clone name PM17

CYP71D14     Petunia hybrida (petunia)
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee June 4, 1999
            58% to 71D6 
            IMT-5 

CYP71D15      Mentha X piperita (peppermint)
            GenEMBL AF124817
            Shari Lupien, Rodney Croteau
            Regio-Specific Cytochrome p450 Limonene Hydroxylases From Mint
            (mentha) Species
            unpublished
            submitted to nomenclature committee 1/24/99
            69% identical to 71D12, 92% identical to 71D13
            (-)4S-Limonene-3-Hydroxylase
            clone name PM2

CYP71D16       Nicotiana tabacum
           GenEMBL AF166332
           Wang,E., Wang,R., Deparasis,J., Gan,S. and Wagner,G.J.
           Isolation of a cytochrome P450 gene from tobacco
           Unpublished
           54% to 71D5 also a tobacco sequence
MQFFNFFSLFLFVSFLFLFKKWKNSNSQTKRLPPGPWKLPILGS
MLHMLGGLPHHVLRDLAKKYGPIMHLQLGEVSLVVISSPGMAKEVLKTHDLAFANRPL
LVAAKIFSYNCMDIALSPYGNYWRQMRKICLLELLSAKNVKSFNSIRQDEVHRMIKFF
RSSPGKPVNVTKRISLFTNSMTCRSAFGQEYKEQDEFVQLVKKVSNLIEGFDVADIFP
SLKFLHVLTGMKAKVMNTHNELDAILENIINEHKKTSKSDGESGGEGIIGVLLRLMKE
GGLQFPITNDNIKAIISDIFGGGTETSSTTINWAMVEMMKNPSVFSKAQAEVREILRG
KETFGEIDVEEFKYLKMVIKETFRLHPPLPLLLPRECREEIDLNGYTIPLKTKVVVNA
WAMGRDPKYWDDVESFKPERFEHNSMDYIGNNYEYLPFGSGRRICPGISFGLANVYFP
LAQLLNHFDWKLPTGINPRNCDLTEAAGAACARKNDLHLIATAYQHCEE

CYP71D17    Prunus dulcis chloroplast  (almond)
            GenEMBL AF107765
            Ma,R. and Oliveira,M.M.
            A putative Prunus dulcis cytochrome P450 gene sequence
            Unpublished
            chloroplast gene encoding chloroplast protein, partial cds.
            70% identical to 71D sequences these sequences may be chloroplast P450s
MFVPRECREKCEIDGYEIPVKSKVIVNAWAIGRDPNYWNEPDSFNPDRFLDSSIDY
KGTNFEYIPFGAGRRMCPGMSFGLANVELPLALLLYHFDWKLPDG

CYP71D18    Mentha spicata (spearmint) Formerly CYP71D12
            GenEMBL AF124815
            Shari Lupien, Rodney Croteau
            Regio-Specific Cytochrome p450 Limonene Hydroxylases From Mint
            (mentha) Species
            unpublished
            submitted to nomenclature committee 1/24/99
            50% identical to 71D7, 69% identical to 71D13
            (-)4S-Limonene-6-Hydroxylase
            Note: due to a mistake on my part the name 71D12 was assigned
            to two sequences.  The sequence of Schroeder has priority
            Since it was submitted and named earlier than Lupiens sequence.

CYP71D19    Capsicum annuum (pepper)
            GenEMBL AF122821
            Oh,B.J., Ko,M.K., Kim,Y.S., Kim,K.S., Kostenyuk,I. and Kee,H.K.
            A cytochrome P450 gene is differentially expressed in compatible
            and incompatible interactions between pepper (Capsicum annuum) and
            the anthracnose fungus, Colletotrichum gloeosporioides
            Mol. Plant Microbe Interact. 12 (12), 1044-1052 (1999)
            58% to 71D6

CYP71D20    Nicotiana tabacum (tobacco)
            GenEMBL AF368376
            Ralston L, Kwon ST, Schoenbeck M, Ralston J, Schenk DJ, Coates RM, 
            Chappell J.
            Cloning, heterologous expression, and functional characterization of
            5-epi-aristolochene-1,3-dihydroxylase from tobacco 
            (Nicotiana tabacum).
            Arch Biochem Biophys. 2001 Sep 15;393(2):222-35.
            Submitted to nomenclature committee Sept. 22, 2000
            81% to 71D4
            gene 1

CYP71D21    Nicotiana tabacum (tobacco)
            GenEMBL AF368377
            Ralston L, Kwon ST, Schoenbeck M, Ralston J, Schenk DJ, Coates RM, 
            Chappell J.
            Cloning, heterologous expression, and functional characterization of
            5-epi-aristolochene-1,3-dihydroxylase from tobacco 
            (Nicotiana tabacum).
            Arch Biochem Biophys. 2001 Sep 15;393(2):222-35.
            Submitted to nomenclature committee Sept. 22, 2000
            82% to 71D4
            gene 2

71E Subfamily

CYP71E1     Sorghum bicolor
            GenEMBL AF029858
            Soren Bak, Rachel Alice Kahn, Hanne Linde Nielsen, Birger
            Lindberg Moller, Barbara Ann Halkier
            Cloning of three A-type cytochromes P450, CYP71E1,
            CYP98, and CYP99 from Sorghum bicolor (L.) Moench by
            a PCR approach and identification by expression in
            Escherichia coli of CYP71E1 as a multifunctional
            cytochrome P450 in the biosynthesis of the cyanogenic
            glucoside dhurrin.
            Plant Molecular Biology 36 (3):393-405, 1998.

CYP71E2     Triticum aestivum (wheat)
            No accession number
            Daniele Werck-Reichhart
            Submitted to nomenclature committee 3/29/2000
            clone name 71g
            58% identical to 71E1 37% to 71F1, 41% to 71G1 and G2

CYP71E3X     Triticum aestivum (wheat) name changed to CYP71M3
            No accession number
            Daniele Werck-Reichhart
            Submitted to nomenclature committee 6/4/2001
            clone name 71-2
            52% identical to 71E1 51% to 71E2, 43% to 71A11
            46% to 71B10, 37% to 71C8, 40% to 71D2, 37% to 71F1
            42% to 71G1v1, 40% to 71J, 38% to 71K

CYP71F1     Triticum aestivum (wheat)
            No accession number
            Hiromasa Imaishi
            40-42% identical to 71D sequences 43% identical to 71A1
            clone name N-1
            submitted to nomenclature committee 1/8/2000

CYP71G1v1   Asparagus
            No accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 3/2/2000
            clone name ASPI-1
            49% to CYP71A1, 40% to 71A14, 45% to 71E1, 43% to 71B9, 
            37% to 71D13, 37% to 71C1, 39% to 71F1

CYP71G1v2   Asparagus
            No accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 3/2/2000
            clone name ASPI-2
            99% to CYP71G1v1 (4 amino acids differences)

CYP71H1X    Triticum aestivum (wheat)
            No accession number
            Daniele Werck-Reichhart 
            55% to 71C4 but only 50% to 71C8, 58% to 71C7
            clone name 71F8I2
            submitted to nomenclature committee July 18, 2000
            This sequence has been reassigned to the 71C subfamily
            It is on the outskirts of the subfamily, but new sequences 
            force it to belong there rather than in a new subfamily.

CYP71J1     Asparagus
            No accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 12/5/2000
            clone name ASPI-3
            47% to CYP71A1, less to other 71 subfamilies

>CYP71K1    Oryza sativa (rice)
            GenEMBL AP002968 
            46% to 71F1 40% to 71A11, 41% to 71G1v2
            40% to 71C7, 40% to 71B24 42% to 71D4 38% to 71E1
MAELPLYLLLLALLVAVPFLCLTRWSLRHGGGGGGRLPPSPWAL
PVIGHLHHVAGALPHRAMRDLARRHGPLMLLRLCELRVVVACTAEAAREVTKTHDLAF
ATRPITPTGKVLMADSVGVVFAPYGDGWRTLRRICTLELLSARRVRSFRAVREEEVGR
LLRAVAAAAAVAALTTPGATAAVNLSERISAYVADSAVRAVIGSRFKNRAAFLRMLER
RMKLLPAQCLPDLFPSSRAAMLVSRMPRRMKRERQEMMDFIDDIFQEHHESRAAAGAE
EDLLDVLLRIQSQDKTNPALTNDNIKTVIIDMFVASSETAATSLQWTMSELMRNPRVM
RKAQDEVRRALAIAGQDGVTEESLRDLPYLHLVIKESLRLHPPVTMLLPRECRETCRV
MGFDVPEGVMVLVNAWAIGRDPAHWDSPEEFAPERFEGVGAADFKGTDFEYIPFGAGR
RMCPGMAFGLANMELALAALLYHFDWELPGGMLPGELDMTEALGLTTRRCSDLLLVPA
LRVPLRDHER

CYP71L1     Hordeum vulgare (barley)
            No accession number
            Kirsten A Nielsen
            Most like CYP71E about 50%
            submitted to nomenclature committee 5/16/2002
            526 amino acids

CYP71M1     Hordeum vulgare (barley)
            No accession number
            Kirsten A Nielsen
            Most like CYP71E about 50%
            submitted to nomenclature committee 5/16/2002
            514 amino acids
            only 42% to 71L1

CYP71M2     Sorghum bicolor 
            No accession number
            Kirsten A Nielsen
            70% to CYP71M1
            submitted to nomenclature committee 8/2/2002
            525 amino acids

CYP71M3     Triticum aestivum (wheat) formerly CYP71E3
            No accession number
            Daniele Werck-Reichhart
            Submitted to nomenclature committee 6/4/2001
            clone name 71-2
            52% identical to 71E1 51% to 71E2, 43% to 71A11
            46% to 71B10, 37% to 71C8, 40% to 71D2, 37% to 71F1
            42% to 71G1v1, 40% to 71J, 38% to 71K, 43% to 71L1, 92% to 71M1

CYP71N1     Musa acuminata (banana)
            GenEMBL AY062168
            Lee,Y.C. and Pua,E.C.
            Cloning and Characterization of Cytochrome P450 in Banana (Musa
            acuminata)
            Unpublished
            50% to 71G1 less to other CYP71 subfamilies

more names exist here for the rice P450s that have not been added yet to the nomenclature pages

CYP71R4     Lolium rigidum (ryegrass)
            No accession
            Hiromasa Imaishi
            Clone W1B11-HT
            63% to rice AP003575 CYP71R2P

more rice subfamilies belong here, not inserted yet

CYP71AH1    tobacco
            no accession number 
            Takashi Yamada
            tobacco sequence 2
            submitted to nomenclature committee 9/9/97
            Formerly 71A11, renamed CYP71AH1 only 46% to 71B38

72A Subfamily

Note on the 72A subfamily.  The 72A subfamily from different species appears to contain 
multiple members.  These sequences are very similar to each other, so they were not present in the common ancestor to the 72A group.  They may represent alleles of the same gene or duplications of a single gene that have diverged slightly.  I have tried to keep families with only one sequence per species with a single name as in CYP72A for all species.  This approach breaks down when multiple alleles or highly similar duplications are present.  The only practical solution is to assign different names to each species as in 72A1, 72A2, 72A3, etc. and use v1, v2, v3 for the highly similar variations in a single species.  Variants had already been assigned to 72A from Catharanthus roseus, but since this was one of the first cases where v numbers were used, the first sequence was not given a v designation.  The second sequence was called v1 and the third v2.  The nomenclature has since been defined such that any new sequence is by default given the v1 designation.  The v1 designation is not used unless other variants are known.  The second sequence is then v2 etc.  To correct this error, the first 72A1 sequence is being relabeled as 72A1v3, while the other two sequences remain the same.  Other species are now assigned different numbers as 72A2 etc. with v numbers given as needed.  It is still acceptable to refer to the 72A subfamily, but different species will now have separate numbers.

CYP72A1v1   Catharanthus roseus
            GenEMBL L19074 (2646bp)
            Mangold,U., Eichel,J., Batschauer,A., Lanz,T., Kaiser,T.,
            Spangenberg,G., Werck-Reichhart,D. and Schroeder,J.
            Gene and cDNA for plant cytochrome P450 proteins (CYP72 family) 
            from Catharanthus roseus: and transgenic expression in tobacco and 
            Arabidopsis thaliana.
            Plant Sci. 96, 129-136 (1994)
            Note: sequence called CYP72B, 8 amino acid differences with
            CYP72A1v3 (see second entry under 72A1v3 for function information)

CYP72A1v2   Catharanthus roseus
            GenEMBL L19075 (1633bp)
            Mangold,U., Eichel,J., Batschauer,A., Lanz,T., Kaiser,T.,
            Spangenberg,G., Werck-Reichhart,D. and Schroeder,J.
            Gene and cDNA for plant cytochrome P450 proteins (CYP72 family) 
            from Catharanthus roseus: and transgenic expression in tobacco and 
            Arabidopsis thaliana.
            Plant Sci. 96, 129-136 (1994)
            Note: sequence called CYP72C, 14 amino acid differences with
            CYP72A1v3 plus a 3 amino acid C-terminal extension.
            (see second entry under 72A1v3 for function information)

CYP72A1v3   Catharanthus roseus L. (Madagascar periwinkle)
            GenEMBL L10081 (1854bp) Swiss Q05047 (524 amino acids)
            Vetter,H.-P., Mangold,U., Schroeder,G., Marner,F.-J.,
            Werck-Reichhart,D. and Schroeder,J.
            Molecular analysis and heterologous expression of 
            an inducible cytochrome P-450 protein from periwinkle
            (Catharanthus roseus L.)
            Plant Physiol. 100, 998-1007 (1992)

NEW         Update on function of CYP72A1 encoded by (L10081):
            Irmler, S., Schršder, G., St-Pierre, B., Crouch, N.P., Hotze, M., 
            Schmidt, J., Strack, D., Matern, U. and Schršder, J. (2000) Indole 
            alkaloid biosynthesis in Catharanthus roseus: new enzyme activities 
            and identification of cytochrome P450 CYP72A1 as secologanin 
            synthase. Plant J. 24, 797-804.
            CYP72A1v3 converts loganin into secologanin.

            GenEMBL X69775 (365bp PCR fragment)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 3 from Fig. 2. (identical to 72A1)

CYP72A1     Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69789 (375bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 1 from Fig. 2.
            (see second entry under 72A1v3 for function information)

CYP72A1     Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69790 (327bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 2 from Fig. 2.
            (see second entry under 72A1v3 for function information)

CYP72A2    Nicotiana plumbaginifolia
           GenEMBL U35226(1787bp)
           LaRosa P.C. and Smigocki, A.C.
           A wound-inducible cytochrome P-450 in Nicotiana plumbaginifolia
           unpublished (1996)

CYP72A3X    Nicotiana tabacum (tobacco)
            no accession number
            Francis Durst
            submitted to nomenclature committee
            Francis Durst denies he ever sent a tobacco CYP72 sequence.  This is  
            Probably an accident, since he did send three tobacco sequences and 
            a wheat CYP72 in one email.  I probably thought they were all 
            tobacco and misnamed this one.

CYP72A4X    Arabidopsis thaliana ESTs
            GenEMBL T13009 (removed from Genbank, same as T04134), T04134 (72A11),     
            T22603 (72A13), H36956 (72A14), T44202 (72A13), R90024 (72A7)
            N-terminal fragments, more than one sequence is present

            GenEMBL T22449 (72A15), T45915 (72A15), H36129 (72A11)
            middle fragments

            GenEMBL Z46541 (72A14), Z46540 (72A14)
            C-terminal fragments

            note: the whole gene sequence can be assembled from these ESTs,
            but it may be a chimera of several isoforms.  There seem to be at 
            least 3 different N-terminals.  
            Note: There is a cluster of 8 CYP72A genes and one pseudogene on
            AB023038.  Therefore, this chimeric sequence has been retired.

CYP72A5    Zea mays
           no accession number (318 amino acids)
           Mike Persans and Mary Schuler
           submitted to nomenclature committee
           PCR4
           formerly CYP95A1 (missnamed due to a frame shift in the PCR fragment)
           ESTs AI855377 (1 amino acid difference), AI637224 (94% identical)

CYP72A5    Zea mays (maize)
           no accession number
           Mike Barrett
           clone A8 most like PCR fragment PCR4 from Mike Persans and Mary Schuler
           The PCR4 fragment was missnamed as CYP95A1 due to a frame shift error in 
           the sequence in the I-helix region.
           also like Arabidopsis GSS BAC end fragment B24203 (67% identical)
           submitted to nomenclature committee 5/15/98
           ESTs AI855377 (1 amino acid difference), AI637224 (94% identical)

146 LLANGLVNHDGEKWAKHRRILNPAFHHEKIKGMMPVFSTCCIEMITRWDNSMPSEGSSEI
    DVWPEFQNLTGDVISRTAFGSNYQEGRRIFELQGELAERLIQSVQTIFIPGYWFLPTKNN
    RRMRAIDVEIRKILREIIGKREKDTKNRETNNDDLLGLLLESNTRQSNGNASLGLTTXDV
    IEECKLFYFAGMET 339

441 ASEFNPERFANGISXATRHQAAFFPFGGGPRICIGQSFALLEAKMTLCTILQRFSFELSP
    SXTHAPYXVITLHP 514

CYP72A6v1      Triticum aestivum (wheat)
           no accession number
           Daniele Werck
           submitted to nomenclature committee 1/20/99
           clone name CYP72A 47% identical to C. roseus CYP72A1

CYP72A6v2  Triticum aestivum (wheat)
           no accession number
           Daniele Werck
           submitted to nomenclature committee 1/20/99
           clone name CYP72B 
           This sequence is 100% identical to the other 72A6v2 sequence 
           from amino acid 130 to the end.  The N-terminal 129 amino acids match 
           no sequences in Genbank.  I suspect this is a chimeric clone. 

CYP72A6v2  Triticum aestivum (wheat)
           no accession number
           Daniele Werck
           submitted to nomenclature committee 1/20/99
           clone name CYP72B' 96% identical to CYP72A6v3 95% identical to  
           CYP72A6v1

CYP72A6v3  Triticum aestivum (wheat)
           no accession number
           Daniele Werck
           submitted to nomenclature committee 1/20/99
           clone name CYP72C 96% identical to CYP72A6v2 95% identical to CYP72A6v1

CYP72A7    Arabidopsis thaliana
           GenEMBL AB023038 40540-42460
           ESTs R90024 (2/26/99)

CYP72A8    Arabidopsis thaliana
           GenEMBL AB023038 42944-44810
           no ESTs (2/26/99)

CYP72A9    Arabidopsis thaliana
           GenEMBL AB023038 45458-47366
           no ESTs (3/1/99)

CYP72A10   Arabidopsis thaliana
           GenEMBL AB023038 47816-49744
           no ESTs (3/1/99)

CYP72A11   Arabidopsis thaliana
           GenEMBL AB023038 50166-52122
           ESTs H36129, T04134 (3/1/99)

CYP72A12P  Arabidopsis thaliana
           GenEMBL AB023038 52192-52485 lone exon 5
           GSS fragment B24203 97% identical
           no ESTs (3/1/99)

CYP72A13   Arabidopsis thaliana
           GenEMBL AB023038 52920-54868
           ESTs T44202, N96036, N96740 (3/1/99)

CYP72A14   Arabidopsis thaliana
           GenEMBL AB023038 62438-64419
           ESTs H36956, Z46541, Z46540 (3/1/99)

CYP72A15   Arabidopsis thaliana
           GenEMBL AB023038 65370-67267
           ESTs T45915, T22449 (3/1/99)

CYP72A16   Zea mays
           No accession number
           Jian Wang and Mary Schuler
           80% to 72A5 EST AI857222
           submitted to nomenclature committee 12/1/99

CYP72A17   Oryza sativa (rice)
           GenEMBL AP002839.1 36553-39431
            Go to sequences

CYP72A18   Oryza sativa (rice)
           GenEMBL AP002839.1 44993-41630
           Hiromasa Imaishi
           Submitted to nomenclature committee 8/18/2000
            Go to sequences

CYP72A19   Oryza sativa (rice)
           GenEMBL AP002839.1 comp(53699-51708)
            Go to sequences

CYP72A20   Oryza sativa (rice)
           GenEMBL AP002839.1 56581-59004
            Go to sequences

CYP72A21   Oryza sativa (rice)
           GenEMBL AP002839.1 61993-63890
           Hiromasa Imaishi
           Submitted to nomenclature committee 3/2/2000
           Clone name CL-8904
           53% identical to 72A15
            Go to sequences

CYP72A22   Oryza sativa (rice)
           GenEMBL AP002839.1 66435-68424
            Go to sequences

CYP72A23   Oryza sativa (rice)
           GenEMBL AP002839.1 72149-74091
            Go to sequences

CYP72A24   Oryza sativa (rice)
           GenEMBL AP002839.1 109970-113787
            Go to sequences

CYP72A25   Oryza sativa (rice)
           GenEMBL AP002839.1 115472-117492
            Go to sequences

CYP72A26    Zea mays (maize)
           No accession number
           Mary Schuler and Jian Wang
           Submitted to nomenclature committee Oct. 2, 2000 
           Clone name 12/7B
           62% to 72A5

CYP72A27    Zea mays (maize)
           No accession number
           Mary Schuler and Jian Wang
           Submitted to nomenclature committee Oct. 23, 2000 
           Clone name 11G
           95% identical to 72A26, but matches three ESTs at points of difference

CYP72A28   Zea mays (maize)
           No accession number
           Mary Schuler and Jian Wang
           Submitted to nomenclature committee Oct. 23, 2000 
           Clone name E5D
           66% to CYP72A26

CYP72A29   Solanum  tuberosum L. May Queen
           No accession  number
           Hisaharu Kato
           Submitted to nomenclature committee 1/15/2002
           84% to 72A2

CYP72A30   Lycopersicon esculentum (tomato)
             GenEMBL AF249329
           Bartoszewski,G., Mujer,C.V., Niemirowicz-Szczytt,K. and
           Smigocki,A.C.
           Tomato (Lycopersicon esculentum) cDNA sequence encoding a     
           protein similar to a cytochrome P450 enzyme
           Unpublished
           74% to 72A29
           note small gap compared to other 72As, may be missing some
           coding sequence 

72B Subfamily

CYP72B1     Arabidopsis thaliana ESTs
            GenEMBL AC003105
            42% identical to C. roseus 72A1
            ESTs T04442

CYP72B2X    Arabidopsis thaliana ESTs
            GenEMBL B96503 (661bp)
            F23A22TF 
            C-terminal PERF region to end
            This sequence is actually part of CYP714A1

CYP72C1    Arabidopsis thaliana
           GenEMBL AC007651 88180-91153
           45% identical to 72A9

73A Subfamily

CYP73A1     Helianthus tuberosus (Jerusalem artichoke) cinnamate 4-hydroxylase
            GenEMBL Z17369 (1620bp) Swiss Q04468 (505 amino acids)
            PIR S28495 A47454 (505 amino acids)
            Teutsch,H.G., Hasenfratz,M.P., Lesot,A., Stoltz,C., Garnier,J.-M.,
            Jeltsch,J.-M., Durst,F. and Werck-Reichhart,D.
            Isolation and sequence of a cDNA encoding the Jerusalem
            artichoke cinnamate 4-hydroxylase, a major plant cytochrome P450
            involved in the general phenylpropanoid pathway.
            Proc. Natl. Acad. Sci. USA 90, 4102-4106 (1993)

CYP73A2     Phaseolus aureus (mung bean) PIR listing has Vigna radiata (mung bean)
            GenEMBL L07634 (1766bp) PIR JC1458 (501 amino acids)
            PIR PC1238 (74 amino acids)
            Mizutani,M., Ward,E.R., DiMaio,J., Ryals,J.A., Ohta,D.
            and Sato,R.
            Molecular cloning and sequencing of a cDNA encoding
            mung bean cytochrome P450 (P450C4H) possessing cinnamate
            4-hydroxylase activity.
            Biochem. Biophys. Res. Commun. 190, 875-880 (1993)

CYP73A3     Medicago sativa (alfalfa) cinnamate 4-hydroxylase
            GenEMBL L11046 (1744bp) PIR S36878 (506 amino acids)
            Fahrendorf,T. and Dixon,R.A.
            Molecular cloning of the elicitor-inducible cinnamic acid
            4-hydroxylase cytochrome P450 from alfalfa.
            Arch. Biochem. Biophys. 305, 509-515 (1993)

CYP73A4     Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69788 (321bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 16 from Fig. 2.

CYP73A4     Catharanthus roseus (Madagascar periwinkle) 
            GenEMBL Z32563 (1713 bp) 
            Hotze,M., Schroeder, G. and Schroeder,J.:  
            Cinnamate 4-hydroxylase from Catharanthus roseus, 
            and a  strategy for the functional expression of 
            plant cytochrome P450 proteins as translational 
            fusions with P450 reductase in Escherichia coli. 
            FEBS Letters 374, 345-350 (1995) 

CYP73A5     Arabidopsis thaliana
            GenEMBL U71080 (5432bp) U71081 (1727bp)
            Bell-Lelong, D.A., Cusamano, J.C., Meyer, K. and Chapple, C.C.
            Cinnamate-4-hydroxylase expression in Arabidopsis.  Regulation
            in response to development and the environment.
            Plant Physiol. 113, 729-738 (1997)

CYP73A5     Arabidopsis thaliana
            GenEMBL U93215
            T06B20.16

CYP73A5     Arabidopsis thaliana
            GenEMBL U37235
            Mignotte-Vieux,C., Kazmaier,M., Urban,P. and Pompon,D.
            unpublished (1999)

CYP73A5     Arabidopsis thaliana
            GenEMBL D78596 (1711bp, 505 amino acids) also D78597 partial seq.
            Mizutani,M., Ohta,D. and Sato,R.
            Isolation of a cDNA and a genomic clone encoding cinnamate
            4-hydroxylase from Arabidopsis and its expression manner in planta
            Plant Physiol. 113, 755-763 (1997)
            P450C4H

CYP73A5     Arabidopsis thaliana EST
            GenEMBL T04086 (480bp) F19837 
            C-terminal fragment
            
CYP73A6     Zea mays
            Sharon Potter
            sequence e
            submitted to nomenclature committee 6/8/94

CYP73A7     Zea mays
            Sharon Potter
            sequence c
            submitted to nomenclature committee 6/8/94
            ESTs AI666136 AW519858.1 BG320001.1 BE639176.1
            php20835.x3.b an STS from the CSHL STS Maize Database    
            http://nucleus.cshl.org/maizegenome/
            currently missing 67 aa at N-terminal

                  IFL LRMGVRNLVV VSTPELAKEV LHTQGVEFGS 
RTRNVVFDIF TGKGQDMVFT VYGDHWRKMR RIMTVPFFTN KVVAQNRAGW 
EEEARLVVED VRKDPEAAAG GVVLRRRLQL MMYNDMFRIM FDRRFDSEHD 
PLFNKLKALN AERSRLSQSF EYNYGDFIPV LRPFLRGYLN RCHDLKTRRM 
KVFEDNFVQE RKXXMAQTGE IRCAMDHILE AERKGEINHD NVLYIVENIN 
VAAIETTLWS IEWGIAELVN HPAIQHKLRE ELASVLGAGV PVTEPDLERL 
PYLQAIVKET LRLRMAIPLL VPHMNLNDGK LAGYDIPAES KILVNAWFLA 
NDPKRWVRPD EFRPERFLEE EKSVEAHGND FRFVPFGVGR RSCPGIILAL 
PIIGITLGRL VQNFQLLPPP GLDKIDTTEK PGQFSNQIAK HATIVCKPLE 
A*

CYP73A8     Zea mays
            Sharon Potter
            sequence f
            submitted to nomenclature committee 6/8/94

CYP73A9      Pisum sativum (pea)
             GenEMBL U29243 (1715bp)
             Frank,M.R., Deyneka,J.M. and Schuler,M.A.
             Cloning of phenylpropanoid pathway P450 monooxygenases expressed in
             Pisum sativum.
             unpublished

CYP73A10    Petroselinum crispum (parsley)
            GenEMBL L38898 (1801bp)
            Logemann,E., Parniske,M. and Hahlbrock,K.
            Modes of expression and common structural features of the complete
            phenylalanine ammonia-lyase gene family in parsley
            Proc. Natl. Acad. Sci. U.S.A. 92, 5905-5909 (1995)
            sequence sent by Edda Koopmann

CYP73A11    Glycine max (soybean)
            GenEMBL X92437 (1787bp)
            Schopfer,C.R. and Ebel,J.
            Identification of elicitor-induced cytochrome P450s of soybean
            (Glycine max L.) using differential display of mRNA
            Mol. Gen. Genet. 258, 315-322 (1998)

CYP73A12    Zinnia elegans
            GenEMBL U19922 (1648bp)
            Ye, E. and Varner, J.E. 
            Expression patterns of cinnamic acid 4-hydroxylase gene during lignification
            in Zinnia. 
            unpublished

CYP73A13    Populus tremuloides (quaking aspen)
            GenEMBL U47293 (1803bp)
            Ge,L. and Chiang,V.L.
            A full length cDNA encoding trans-cinnamate 4-hydroxylase from developing 
            xylem of Populus tremuloides 
            Plant Physiol. 112, 861 (1996)

CYP73A14    Glycyrrhiza echinata (licorice)
            GenEMBL D87520
            Akashi,T., Aoki, T., Takahashi,T., Kameya,N., Nakamura, I. and Ayabe, S.
            Cloning of cytochrome P450 cDNAs from cultured Glycyrrhiza echinata L. cells 
            and their transcriptional activation by elicitor treatment.
            Plant Science 126, 39-47 (1997)

CYP73A14v1  Glycyrrhiza echinata (licorice)
            GenEMBL D89430
            Akashi,T., Aoki, T., Takahashi,T., Kameya,N., Nakamura, I. and Ayabe, S.
            Cloning of cytochrome P450 cDNAs from cultured Glycyrrhiza echinata L. cells 
            and their transcriptional activation by elicitor treatment.
            Plant Science 126, 39-47 (1997)
            C-terminal PCR fragment with 4/82 amino acid differences to 73A14

CYP73A15    Phaseolus vulgaris (french bean)
            Y09447 (1799bp) Y09448 (2280bp) Y09449 (1065bp)
            Jupe,S.C., Werck-Reichhart,D. and Bolwell,G.P.
            Molecular cloning of a novel CYP73 from French bean: induction by
            elicitor and during xylogenesis.
            Unpublished

CYP73A16    Populus kitakamiensis (hybrid aspen)
            GenEMBL D82815(1737bp) mRNA
            GenEMBL D82814(2923bp) partial gene sequence
            GenEMBL D82812, D82813, D82814 closely related genes
            Kawai S, Mori A, Shiokawa T, Kajita S, Katayama Y, Morohoshi N.  
            Isolation and analysis of cinnamic acid 4-hydroxylase homologous genes from a 
            hybrid aspen, Populus kitakamiensis.  
            Biosci Biotech Biochem. 60, 1586-97

CYP73A17    Triticum aestivum (wheat)
            no accession number 
            Francis Durst
            submitted to nomenclature committee

CYP73A17    Triticum aestivum (wheat) 
            GenEMBL AF123608
            Batard,Y., Hehn,A., Nedelkina,S., Schalk,M., Pallett,K.,
            Schaller,H. and Werck-Reichhart,D.
            Increasing expression of P450 and P450-reductase proteins from
            monocots in heterologous systems
            Arch. Biochem. Biophys. 379 (1), 161-169 (2000)

CYP73A18    L. esculentum (tomato)
            GenEMBL Z70216 PCR fragment (202bp)
            this sequence differs from 73A24, but this might be due to errors
            there are no other ESTs that match this PCR fragment.

CYP73A19    Cicer arietinum (chickpea)
            GenEMBL AJ007449
            Overkamp, S. and W. Barz, W.  Isolation of a Full Length cDNA Encoding 
            Trans-Cinnamate 4-Hydroxylase (Accession No. AJ007449) from Chickpea (Cicer 
            arietinum L.). (PGR99-086) Plant Physiol. 120, 635 (1999)
            91% identical to Medicago sativa CYP73A3

CYP73A20    Pinus taeda (loblolly pine)
            GenEMBL AF096998
            Anterola,A.M., Jeon,J.H., Davin,L.B. and Lewis,N.G.
            Pinus taeda mRNA for trans-cinnamate 4-hydroxylase (PTC4H) is
            induced in cell suspension cultures by 8% sucrose/20mM KI treatment
            Unpublished

CYP73A21    Capsicum chinense (habanero chile)
            GenEMBL AF088847
            Curry,J. and O'Connell,M.A.
            Cinnamic acid 4-hydroxylase from habanero chile
            Unpublished

CYP73A22     Mesembryanthemum crystallinum
             GenEMBL AF097664
             Michalowski,C.B. and Bohnert,H.J.
             cinnamate 4-hydroxylase mRNA from the common ice plant
             Unpublished

CYP73A23    Pinus taeda
            GenEMBL AI812813, AA556941, AI812771, AI812842, AI919827
            sequence made from ESTs only
            missing 160 amino acids at N-terminal
            81% to 73A20 and many other 73A sequences

CYP73A24      tomato
           GenEMBL ESTs only
AI484139  EST248946 cLER1C5
AI894646  EST264089 cLEC4L12
AI490789  EST241497 cLEB3H9
AI774477  EST255577 cLER12O4
AI895653  EST265096 cLEC9O20
AI484136  EST248943 cLER1C5
AI899232  EST268675 cLED37P6
AI490786  EST241494 cLEB3H9
AI774140  EST255240 cLER10B24
AI773934  EST255034 cLER8N1
AI487946  EST246268 cLED19L20
AI484879  EST243140 cLED3A21
AI894393  EST263848 cLEC4G23
AI895830  EST265273 cLEC10A6
AI895463  EST264906 cLEC7J20

MDLLLLEKTLIGLFFAILIAIIISKLRSKRFKLPPGPIPVPIFGNWLQVGDDLNHRNLTE 
YAKKFGDVFLLRMGQRNLAVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVF 
TVYGEHWRKMRRIMTVPFFTNKVVQQYRGGWESEAASVVEDVKKN
PESATNGIVLRKRLQLMMYNNMFRIMFDRRFESEDDPLFVKLKALNGERS
RLAQSFEYNYGDFIPILRPFLRGYLKICKEVKEKRLKLFKDYFVDERKKL
ANTKSMDSNALKCAIDHILDAQQKGEINEDNVLYIVENINVAAIETTLWSIEW
GIAELVNHPHIQKKLRDEIDTVLGPGVQVSEPDMPKLPYLQAVIKETLRL
RMAIPLLVPHMNLHDAKLAAYDIPAESKILVNAWWLANNPAHWKKPEEFRPERFLEEEKHVE 
ANGNDFRFLPFGVGSRSCPGIILALPILGITIGRLVQNFEMLPPPGQSKLDTSEKGGQFSL 
HILKHSTIVMKPRSF*

CYP73A25    Gossypium arboreum (cotton)
            GenEMBL AF286647
            Xiao-Ya Chen and Ping Luo
            Clone name LP89
            92% to 73A16

CYP73A26    Gossypium arboreum (cotton)
            GenEMBL AF286648
            Xiao-Ya Chen and Ping Luo
            Clone name LP125
            91% to 73A25

CYP73A27    Nicotiana tabacum (tobacco)
            GenEMBL AF368378
            Ralston L, Kwon ST, Schoenbeck M, Ralston J, Schenk DJ, Coates RM, 
            Chappell J.
            Cloning, heterologous expression, and functional characterization of
            5-epi-aristolochene-1,3-dihydroxylase from tobacco 
            (Nicotiana tabacum).
            Arch Biochem Biophys. 2001 Sep 15;393(2):222-35.
            Submitted to nomenclature committee Oct. 10, 2000
            67% to 73A22, 71% to 73A15, 72% to 73A29
            clone name cDNA 1

CYP73A28    Nicotiana tabacum (tobacco)
            GenEMBL AF368379
            Ralston L, Kwon ST, Schoenbeck M, Ralston J, Schenk DJ, Coates RM, 
            Chappell J.
            Cloning, heterologous expression, and functional characterization of
            5-epi-aristolochene-1,3-dihydroxylase from tobacco 
            (Nicotiana tabacum).
            Arch Biochem Biophys. 2001 Sep 15;393(2):222-35.
            Submitted to nomenclature committee Oct. 10, 2000
            95% to 73A27
            clone name cDNA 2

CYP73A29    Citrus sinensis 
            GenEMBL AF255013.1
            Betz,C., McCollum,T.G. and Mayer,R.T.
            Differential expression of two cinnamate 4-hydroxylase genes in
            Citrus
            Unpublished            
            cinnamate 4-hydroxylase (C4H1)
            72% to 73A27

CYP73A30    Lithospermum erythrorhizon (a Japanese medicinal plant)
            No accession number
            Hajime Mizukami
            Submitted to nomenclature committee Oct. 25, 2000
            Clone name LEC4H1 83% to 73A4, 91% identical to 73A31

CYP73A31    Lithospermum erythrorhizon (a Japanese medicinal plant)
            No accession number
            Hajime Mizukami
            Submitted to nomenclature committee Oct. 25, 2000
            Clone name LEC4H2 91% identical to 73A30

CYP73A32    Ruta graveolens (common rue)
            GenEMBL AJ309127
            Antoine Gravot
            Submitted to nomenclature committee 3/29/01
            87% to cotton CYP73A25

CYP73A33    Sorghum bicolor 
            No accession number
            Ron Coolbaugh
            95% identical to 73A7, 90% to 73A17, 73% to 73A6, 61% to 73A8

CYP73A34    Hordeum vulgare (barley)
            Assembled from overlapping ESTs
            88% to 73A33, 87% to 73A7
BF620285.2 1-176 (no diffs) BE413007.1 49-282 (no diffs) BG367496 128-302 (no diffs)
AL504406.1 182-383 (no diffs) BE519761.2 245-401 (no diffs) BE412402.1 383-501 (no diffs)
MDVLLLEKALLGLFAAAVLAIAVAKLAGKRFRLP
PGPSGAPIVGNWLQVGDDLNHRNLMGLAKRFGEVFLLRMGVRNLVVVSSPELAKEVLHTQ
GVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVAQNRVGWEEEA
RLVVEDLRADPAAATKGVVVRRRLQLMMYNDMFRIMFDRRFETVADPLFNQLKALNA
ERSILSQSFDYNYGDF
IPVLRPFLRRYLNRCTNLKTKRMKVFEDHFVQQRKEALEKTGEIKCAMDHILEAERKGEI
NHDNVLYIVENINVAAIETTLWSIEWGLAELVNHPEIQQKLREEIVAVLGPGTPVTEPDL
ERLPYLQSVVKETLRLRMAIP
LLVPHMNLSDAKLAGYDIPAESKILVNAWFLANDPKRWVRADEFRPERFLEEERAVEANG
NDFRFVPFGVGRRSCPGIILALPIIGITLGRLVQNFQLLPPLGKDKIDTTEKPGQFSNQI
RNHATVVCKPLKA*

CYP73A35P   Oryza sativa (rice) 
            GenEMBL AP003446.1 March 29, 2001
                    AP003302.1  Feb. 21, 2001
            Both sequences have the same frameshifts so
            This is probably a pseudogene

MDLLFVERLLVGLLAAAVVAIAVSKLRGRKLRLPPGPTPVPVFGNWLQVGDDLNHRNLAA
LARRFGDIFLLRMGQRNLVVVSSPPLAREVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFT
VYGDHWRKMRRIMTVPFFTGKVVQRHRAGWEAEAAAVVDGLRADPAAA 168 (25 nuc. deletion and frameshift in both sequences)
175 RRRLQLMMYSNVYRIMFDRRFESADDPLFLRLKALNGERSRLAQSFEYNYGDFIPILRPF
LRGYLRICEEVKETRLKLFKDFFLEERK (1)
KLASTKAMDNNGLKCAIDHILEAQQKGEINEDNVLYIVENINVA (1)
AIETTLWSMEWAIAEL (2 nuc. insertion and frameshift in both seqs.)
VNHGEIQEKLRRELDTVLGPGRQITEPDTHRLPYLQAVVKETLRLRMAIPLLVPHMNLRD
AELAGYGIPAESKVLVNAWYLANDPGRWRRPEEFRPERFLEEERNVEANGNDFRYLPSGA
GRRSCPGIVLALPILGVTIGRLVQNFELLPPPGKDRVDTTEKGGQFSLHILKHSTIVAKPRAF*

CYP73A36    Citrus sinensis 
            GenEMBL AF255014.2
            Betz,C., McCollum,T.G. and Mayer,R.T.
            Differential expression of two cinnamate 4-hydroxylase 
            genes in Citrus
            Unpublished
            88% to 73A1

CYP73A37    Citrus paradisi (Marsh Grapefruit)
            GenEMBL AF378333.1
            Legrum,W., McCollum,T.G., Doostdar,H., Shatters,R. and Mayer,R.T.
            Cinnamate 4-hydroxylase in Marsh grapefruit flavedo
            Unpublished
            This sequence is 100% identical to 73A36 from aa 35 ITV to the end
            The N-terminal of 73A36 is conserved on other 73As but the 73A37 N-
            terminal is not conserved.  I suspect it is not processed correctly
            This may be the same gene as 73A36

CYP73A35P   rice
            aaaa01004255.1 $PI (indica ) ortholog of 73A35P

CYP73A38    rice
            aaaa01002376.1 $FI (indica ) ortholog to AQ256364.1 

CYP73A39    rice
            aaaa01006093.1a $FI CYP73 (indica ) 99% to AP004850.1b

CYP73A40    rice
            aaaa01006093.1b $FI CYP73 (indica ) 99% to AP004850.1a
            98% to AAAA01006093.1a 73A39

CYP73A41    Ammi majus L. , Apiaceae (Bishops weed)
            GenEMBL
            Silvia Huebner
            Submitted Jan 7, 2003
            Only 8 amino acid differences to CYP73A10 from Petroselinum crispum
            (parsley)

CYP73       Phaseolus vulgaris (kidney bean)
            PIR S34739 (23 amino acids)
            Rodgers, M.W., Zimmerlin, A., Werck-Reichhart, D. and Bolwell, G.P.
            Microsomally associated heme proteins from French bean:
            characterization of the cytochrome P450
            cinnamate-4-hydroxylase and two peroxidases.
            Arch. Biochem. Biophys. 304, 74-80 (1993)

74A Subfamily

Note on nomenclature of 74A sequences.  Historically, each species has had only one 74A gene described.
This was true up until 2000 when the tomato and Hordeum vulgare both had two 74A genes.  For simplicity in the 
Nomenclature, 74A sequences were not numbered sequentially, but they were just named 74A.  With the discovery of 
multiple 74As in tomato and Hordeum it became necessary to assign numbers to the sequences.  Once more, to keep the 
nomenclature simple, all sequences from species with only one 74A are named CYP74A1.  Those sequences that are from 
species with two 74As have a number assigned to distinguish them from 74A1.  

CYP74A1     Linum usitatissimum (flaxseed)
            GenEMBL U00428 (2038bp)
            Song,W.-C., Funk,C.D. and Brash,A,R.
            Molecular cloning of an allene oxide synthase: A cytochrome
            P450 specialized for the metabolism of fatty acid hydroperoxides.
            Proc. Natl. Acad. Sci. USA 90, 8519-8523 (1993)
            Note: This sequence has two exceptions to the P450 motif.

CYP74A1     Parthenium argentatum (guayule, a desert shrub)
            GenEMBL X78166 (1674bp)
            Pan,Z., Durst,F., Werck-Reichhart,D., Gardner,H.W., Camara,B.,
            Cornish,K. and Backhaus,R.A.
            The major protein of guayule rubber particles is a cytochrome
            P450: Characterization based on cDNA cloning and spectroscopic
            analysis of the solubilized enzyme and its reaction products
            J. Biol. Chem. 270, 8487-8494 (1995)

CYP74A1     Arabidopsis thaliana
            GenEMBL X92510 (1799bp)
            Laudert D., Pfannschmidt, U., Lottspeich, F., Hollanderczytko, H., and 
            Weiler, E.W.
            Cloning, molecular and functional characterization of Arabidopsis thaliana allene 
            oxide synthase (CYP-74), the first enzyme of the octadecanoid pathway to 
            jasmonates.
            J. Mol. Biol. 31, 323-335 (1996)
            Note: The EST N65720 matches this sequence closely, but not completely.

CYP74A1     Arabidopsis thaliana
            GenEMBL AB007647

CYP74A1     Arabidopsis thaliana
            GenEMBL Y12636
            Kubigsteltig,I.I., Laudert,D. and Weiler,E.W.
            Structure and regulation of the Arabidopsis thaliana allene oxide
            synthase gene
            Unpublished

CYP74A1    Arabidopsis thaliana
           GenEMBL AF172727
           Staswick,P.E.
           Sequence of an Allene Oxide Synthase cDNA from Arabidopsis thaliana
           (Accession No. AF172727). (PGR99-130)
           Plant Physiol. 121 (1), 312 (1999)

CYP74A1    Arabidopsis thaliana
           GenEMBL N65720(426bp)
           middle region starting about 234 amino acids in.

CYP74A1     Lycopersicon esculentum (tomato)
            GenEMBL AJ271093
            Sivasankar,S., Sheldrick,B. and Rothstein,S.J.
            Expression of allene oxide synthase determines defense-gene
            activation in tomato
            Unpublished
            64% to Arabidopsis 74A1, 70% to tomato 74A2

CYP74A1     Hordeum vulgare
            GenEMBL AJ250864
            Maucher,H., Hause,B., Feussner,I., Ziegler,J. and Wasternack,C.
            Allene oxide synthases of barley (Hordeum vulgare cv. Salome):
            tissue specific regulation in seedling development
            Plant J. 21 (2), 199-213 (2000)
            53% to Arabidopsis AOS, 89% to Hordeum 74A3

>CYP74A1    Nicotiana attenuata 
            GenEMBL AJ295274 16-NOV-2001 
            mRNA for allene oxide synthase (aos gene).

CYP74A1P1   Lupinus luteus (yellow lupine)
            GenEMBL Z49255 comp(1719-2132)
            possible pseudogene of CYP74A
            42% identical to 74A of guayule, nearly identical to 74AP2

CYP74A1P2   Lupinus luteus (yellow lupine)
            GenEMBL Z49255 comp(4284-4697)
            possible pseudogene of CYP74A
            42% identical to 74A of guayule
            BM74B

CYP74A2     Lycopersicon esculentum (tomato)
            GenEMBL AF230371
            Howe,G.A., Lee,G.I., Itoh,A., Li,L. and DeRocher,A.E.
            Cytochrome P450-dependent metabolism of oxylipins in tomato.
            Cloning and expression of allene oxide synthase and fatty acid
            hydroperoxide lyase
            Plant Physiol. 123 (2), 711-724 (2000)
            63% to Arabidopsis 74A1, 70% to tomato 74A1

CYP74A3     Hordeum vulgare
            GenEMBL AJ250864
            Maucher,H., Hause,B., Feussner,I., Ziegler,J. and Wasternack,C.
            Allene oxide synthases of barley (Hordeum vulgare cv. Salome):
            tissue specific regulation in seedling development
            Plant J. 21 (2), 199-213 (2000)
            54% to Arabidopsis AOS, 89% to Hordeum 74A1

74B Subfamily

CYP74B1    Capsicum annuum (bell pepper)
           GenEMBL U51674 (1647bp)
           Matsui, K. Shibutani,M., Kajiwara,T. and Hase,T.
           fatty acid hydroperoxide lyase
           unpublished

CYP74B2     Arabidopsis thaliana
            GenEMBL Z97339 full length EST T20864 (367bp)
            Newman,T.
            unpublished (1994)
            N-terminal 121 amino acids, different from X92510 full length 74A sequence.

CYP74B2     Arabidopsis thaliana
            GenEMBL AF087932
            Bate,N.J., Sivasankar,S., Moxon,C., Riley,J.C.M., Thompson,J.E. and
            Rothstein,S.J.
            Molecular characterization of an arabidopsis gene encoding
            hydroperoxide lyase, a cytochrome P-450 that is wound inducible
            Plant Physiol. 117, 1393-1400 (1998)

CYP74B3v1     Lycopersicon esculentum (tomato)
            GenEMBL AJ239065
            Sheldrick,B.
            Thesis (1999) University of Guelph, Dept. of Molecular Biology and
            Genetics, Guelph, ON, Canada
            58% to 74B2
IPIMNPAPLSTPAPVTLPVRSIPGSYGLPLVGPIADRLDYFWFQ
KPENFFTKRMEKHKSTVFRTNVPPCFPFFGSVNPNVVAVLDVKSFSHLFDMEIVEKAN
VLVGDFMPSVVYTGDMRVCAYLDTSEPKHAQIKNFSQDILKRGSKTWVPTLLKELDTM
FTTFEADLSKSNTASLLPALQKFLFNFFSLTILGADPSVSPEIANSGYIFLDSWLAIQ
LAPTVSIGVLQPLEEILVHSFAYPFFLVKGNYEKLVQFVKNEAKEVLSRAQTEFQLTE
QEAIHNLWFILGFNAFGGFSIFLPTLLGNLGDEKNADMQEKLRKEVRDKVGVNPENLS
FESVKEMELVQSFVYETLRLSPPVPSQYARARKDFKLSSHDSVYEIKKGELLRGYQPL
VMKDPKVFDEPEKFVLERFTKEKGKELLNYLFWSNGPQTGRPTESNKQCAAKDMVTLT
ASLIVAYIFQKYDSVSFSSGSLTSVKKAS

CYP74B3v2     Lycopersicon esculentum (tomato)
            GenEMBL AF230372
            Howe,G.A., Lee,G.I., Itoh,A., Li,L. and DeRocher,A.E.
            Cytochrome P450-dependent metabolism of oxylipins in tomato.
            Cloning and expression of allene oxide synthase and fatty acid
            hydroperoxide lyase
            Plant Physiol. 123 (2), 711-724 (2000)
            4 amino acid diffs with 74B3v1

CYP74B4v1     Medicago sativa (alfalfa)
              GenEMBL AJ249245
              Noordermeer,M.A., van Dijken,A.J.H., Smeekens,S.C.M., Veldink,G.A.
              and Vliegenthart,J.F.G.
              Cloning and expression of alfalfa hydroperoxide lyase genes
              characterization of 13-hydroperoxide lyase isoenzymes with an
              unusual presequence and a proposal for a reaction mechanism                  
              63% identical to 74B2 61% to 74B1 and 74B3
              submitted to the nomenclature committee 8/23/99

CYP74B4v2     Medicago sativa (alfalfa)
              GenEMBL AJ249246
              Noordermeer,M.A., van Dijken,A.J.H., Smeekens,S.C.M., Veldink,G.A.
              and Vliegenthart,J.F.G.
              Cloning and expression of alfalfa hydroperoxide lyase genes
              characterization of 13-hydroperoxide lyase isoenzymes with an
              unusual presequence and a proposal for a reaction mechanism                  
              97.5% identical to v1
              the three forms show different activities
              submitted to the nomenclature committee 8/23/99

CYP74B4v3     Medicago sativa (alfalfa)
              GenEMBL AJ249246
              Noordermeer,M.A., van Dijken,A.J.H., Smeekens,S.C.M., Veldink,G.A.
              and Vliegenthart,J.F.G.
              Cloning and expression of alfalfa hydroperoxide lyase genes
              characterization of 13-hydroperoxide lyase isoenzymes with an
              unusual presequence and a proposal for a reaction mechanism                  
              99% identical to v1
              the three forms show different activities
              submitted to the nomenclature committee 8/23/99

CYP74B5      Psidium guajava (guava)
             No accession number
             Tijet N, Waspi U, Gaskin DJ, Hunziker P, Muller BL, Vulfson EN, 
             Slusarenko A, Brash AR, Whitehead IM.
             Purification, molecular cloning, and expression of the gene 
             encoding fatty acid 13-hydroperoxide
             lyase from guava fruit (Psidium guajava).
             Lipids. 2000 Jul;35(7):709-20.
             69% identical to CYP74B3
             submitted to nomenclature committee 4/14/00

CYP74B6P     Cucumis sativus (cucumber)
             GenEMBL AF229812
             Matsui,K., Wilkinson,J., Hiatt,B., Knauf,V. and Kajiwara,T.
             Fatty acid hydroperoxide lyases in cucumber hypocotyls
             Unpublished

74C Subfamily

CYP74C1      Cucumis sativus (cucumber)
             GenEMBL AF229811
             Matsui,K., Wilkinson,J., Hiatt,B., Knauf,V. and Kajiwara,T.
             Fatty acid hydroperoxide lyases in cucumber hypocotyls
             Unpublished

CYP74C2      Cucumis melo (cantaloupe melon)
             GenEMBL AF081955
             Tijet N. et al (2001) Arch. Biochem. Biophys. 386, 281-289.
             a hydroperoxide lyase with specificity for both 9- and
             13-hydroperoxides of linoleic and linolenic acids

CYP74C3      Lycopersicon esculentum (tomato)
             No accession number
             Gregg Howe
             Submitted to nomenclature committee May 16, 2001
             57% to 74C1 58% to 74C2
             clone name LeAOS3

CYP74C4      Lycopersicon esculentum (tomato)
             No accession number
             Gregg Howe
             Submitted to nomenclature committee Nov. 28, 2001
             61% to 74C2 60% to 74C1 58% to 74C3

CYP74D1      Lycopersicon esculentum (tomato)
             GenEMBL AF317515
             Itoh A, Howe GA (2001) Molecular cloning of a divinyl ether synthase.
             Identification as a novel CYP74 cytochrome P450. J. Biol. Chem. 276: 3620-3627
             Submitted to nomenclature committee Aug. 28, 2000
             divinyl ether synthase (LeDES)
             54% to 74C4 50% to 74C2

CYP74D2      Solanum tuberosum (potato)
             GenEMBL AJ309541
             Stumpe,M., Kandzia,R., Goebel,C., Rosahl,S. and Feussner,I.
             A pathogen induced divinyl ether synthase (CYP74D)from potato
             suspension cultures
             Unpublished
             divinyl ether synthase (LeDES)
             96% identical to 74D1 51% to 74C2

75A Subfamily

CYP75A1     Petunia hybrida cv. Blue Star
            GenEMBL X71130 (1326bp) PIR S32110 (425 amino acids)
            Toguri,T., Azuma,M. and Ohtani, T.
            The cloning and characterization of a cDNA encoding a cytochrome P450 
            from the flowers of Petunia hybrida.
            Plant Sci. 94, 119-126 (1993)

CYP75A1     Petunia hybrida
            GenEMBL Z22544 (1740bp) PIR S33515 and S38984 (508 amino acids)
            Holton,T.A., Brugliera,F., Lester,D.R., Tanaka,Y., Hyland,C.D., 
            Menting,J.G.T., Lu,C.-Y., Farcy,E., Stevenson,T.W. and       
            Cornish,E.C.
            Cloning and expression of cytochrome P450 genes controlling flower 
            colour
            Nature 366, 276-279 (1993)

CYP75A1     Petunia hybrida
            GenEMBL D14588 (1846bp)
            Ohbayashi,M., Shimada,Y. Nakano,R., Kiyokawa,S. and 
            Kikuchi,Y.
            unpublished (1994)
            flavanoid 3, 5' hydroxylase

CYP75A2     Solanum melongena cv. Sinsadoharanasu (eggplant)
            GenEMBL X70824 (1696bp) Swiss P37120 (513 amino acids)
            PIR S43342 (513 amino acids)
            Toguri,T., Umemoto,N., Kobayashi,O. and Ohtani,T.
            Activation of anthocyanin synthesis genes by white light in eggplant 
            hypocotyl tissues, and identification of an inducible P-450 cDNA.
            Plant Molec. Biol. 23, 933-946 (1993)

CYP75A3     Petunia hybrida
            GenEMBL Z22545 (1923bp) PIR S33521 and S38985 (506 amino acids)
            Holton,T.A., Brugliera,F., Lester,D.R., Tanaka,Y., Hyland,C.D., 
            Menting,J.G.T., Lu,C.-Y., Farcy,E., Stevenson,T.W. and       
            Cornish,E.C.
            Cloning and expression of cytochrome P450 genes controlling flower
            colour
            Nature 366, 276-279 (1993)

CYP75A4     Gentiana triflora 
            GenEMBL D85184 (1666bp)
            Tonaka,Y. Yonekura,K., Fukuchi-Mizutani,M., Fukui,Y. Fujiwara,H.
            Ashikari,T. and Kusumi,T. 
            Molecular and biochemical characterization of three anthocyanin synthetic
            enzymes from Gentiana triflora
            Plant Cell Physiol. 37, 711-716 (1996)

CYP75A5     Eustoma grandiflorum (lisianthus)
            GenEMBL U72654 (2124bp)
            Nielsen, K.M. and Podivinsky,E.
            cDNA cloning and expression of a flavinoid 3'5' hydroxylase from petals
            of Lisianthus (Eustoma grandiflorum Grise)
            unpublished (1996)

CYP75A6     Campanula medium
            GenEMBL D14590 (1927bp)
            Ohbayashi,M.

CYP75A7     Eustoma russellianum
            GenEMBL D14589 (2174bp)
            Ohbayashi,M.

CYP75A8     Catharanthus roseus (Madagascar periwinkle)
            GenEMBL AJ011862 (1595bp)
            Kaltenbach,M., Schroeder,G., Schmelzer,E. Lutz,V. and Schroeder,J.
            Flavonoid hydroxylase from Catharanthus roseus: cDNA, heterologous
            expression, enzyme properties and cell type specific expression
            in plants.
            Plant J. 19, 183-193 (1999)

CYP75A9     Lycianthes rantonnei 
            GenEMBL AF313490
            Eder,C.M. and Forkmann,G.
            Lycianthes rantonnetii flavonoid 3',5'-hydroxylase
            Unpublished
            86% identical to 75A2

CYP75A10    Torrenia hybrida (cultivar:Summerwave Blue)
            GenEMBL AB012925
            Suzuki,K., Xue,H., Tanaka,Y., Fukui,Y., Fukuchi-Mizutani,M.,
            Murakami,Y., Katsumoto,Y., Tsuda,S. and Kusumi,T.
            Flower color modifications of Torenia hybrida by cosuppression of
            anthocyanin biosynthesis genes
            Mol. Breed. 6, 239-246 (2000)
            73% to CYP75A8

CYP75B1     Arabidopsis thaliana
            GenEMBL AL133421 and AB005249 at end of cosmid
            GenEMBL AF241643 exon 1, AF241644 exon 2, AF241645 exon 3, AF241646 exon 4,
            GenEMBL AF241647 exon 1 mutant

CYP75B2     Petunia hybrida
            GenEMBL AF155332 
            Brugliera, F., Barri-Rewell, G., Holton, T.A. and Mason, J.G.
            Isolation and Characterization of a flavonoid 3'-hydroxylase cDNA clone 
            corresponding to the Ht1 locus of Petunia hybrida. 
            The Plant Journal, 19, 441-451 1999 
            Florigene Ltd.
            clone OGR-38    (67% identical to 75B1 N-terminal exon)
            submitted to nomenclature committee 6/9/98

CYP75B3   Oryza sativa (rice)
          GenEMBl AC021892
          chromosome 10 clone 53D03 
          seq about 60% to 75B1 Missing part of N-term

61678 MDVVPLPLLLGSLAVSAAVWYLVYFLRGGTGANAARKRRPLPPGPRGXXXXGNL
PQLGXXXXXXXXXXXXXYGPLFRLRF 61442
XXXXXXXXXX
122805 APLAPSFLRGHDANF 122850 frame shift
122852 ATGPPNSGAEH
122885 VAYNYQDLVFAPTVALARLRKLCALHLFSAKALDDLRAVREGEVALMVRNLARQQAA 123055
123056 SVALGQEANVCATNTLARATIGHRVFAVDGGEGAREFKEMVVELMQLAGVFNVGDFVPA 123232
123233 LRWLDPQGVVAKMKRLHRRYDNMMNGFINERKAGAQPDGVAAGEHGNDLLSVLL 123394
123395 ARMQEEQKLDGDGEKITETDIKALLLNLF 123574
123575 TAGTDTTSSTVEWALAELIRHPDVLKEAQHELDTVVGRGRLVSESDLPRLPYLTAVIKET 123754
123755 FRLHPSTPLSLPREAAEECEVDGYRIPKGATLLVNVWAIARDPTQWPDPLQYQPSRFLPG 123934
123935 RMHADVDVKGADFGLIPFGAGRRICAGLSWGLRMVTLMTATLVHGFDWTLANGATPDKLN 124114
124115 MEEAYGLTLQRAVPLMVQPVPRLLPSAYGV 124204

CYP75B4      Perilla frutescens var. crispa (Lamiaceae) (an Asiatic mint that produces oil seeds, Red Perilla, 
             beefsteak plant, chinese basil, purple mint)
             GenEMBL AB045593
             C. Kitada, M. Yamazaki, Y. Tanaka and K. Saito
             69% to 75B2
             Flavonoid 3'-hydroxylase
             clone name SHT12

CYP75B5     Callistephus chinensis 
            GenEMBL AF313489
            Eder,C.M. and Forkmann,G.
            Callistephus chinensis flavonoid 3',5'-hydroxylase
            Unpublished
            66% identical to CYP75B2

CYP75B6     Callistephus chinensis 
            GenEMBL AF313488
            Eder,C.M. and Forkmann,G.
            Callistephus chinensis putative flavonoid 3'-hydroxylase
            Unpublished
            73% identical to CYP75B5

CYP75B7    Matthiola incana 
           GenEMBL AF313491
           Eder,C.M. and Forkmann,G.
           Matthiola incana flavonoid 3'-hydroxylase
           Unpublished
           63% identical to 75B5

CYP75B8    Pelargonium x hortorum 
           GenEMBL AF315465
           Eder,C.M. and Forkmann,G.
           Sequence of flavonoid 3'-hydroxylase
           Unpublished
           64% identical to 75B5

CYP75B9    Gentiana triflora (gentian)
           No accession number
           Yukiko Ueyama from Dr. Ohkawa's lab Kobe, Japan
           flavonoid 3'-hydroxylase (F3'H)
           submitted to nomenclature committee March 21, 2001
           71% identical to CYP75B2

CYP75B10   Torenia hybrida (torenia hybrid)
           No accession number
           Yukiko Ueyama from Dr. Ohkawa's lab Kobe, Japan
           flavonoid 3'-hydroxylase (F3'H)
           submitted to nomenclature committee March 21, 2001
           67% identical to CYP75B2

76A Subfamily

CYP76A1     Solanum melongena cv. Sinsadoharanasu (eggplant)
            GenEMBL X71658 (1571bp) Swiss P37121 (467 amino acids)
            PIR S38535 (467 amino acids)
            Toguri,T., Kobayashi,O. and Umemoto,N.
            The cloning of eggplant seedling cDNAs encoding proteins from a
            novel cytochrome P450 family (CYP76)
            Biochim. Biophys Acta 1216, 165-169 (1993)
            Note: clone name F94 also called CYPEG8

CYP76A2     Solanum melongena cv. Sinsadoharanasu (eggplant)
            GenEMBL X71657 (1827bp) Swiss P37122 (505 amino acids)
            PIR S38534 (505 amino acids)
            Toguri,T., Kobayashi,O. and Umemoto,N.
            The cloning of eggplant seedling cDNAs encoding proteins from a
            novel cytochrome P450 family (CYP76)
            Biochim. Biophys Acta 1216, 165-169 (1993)
            Note: clone name G17 also called CYPEG7.

CYP76A3      Petunia
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 6/22/98
            clone IMT-4 64% identical to 76A2

CYP76A4      Petunia
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 6/22/98
            clone IMT-6 63% identical to 76A1 and 76A3

CYP76A5      Petunia
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 1/5/99
            clone IMT-9 66% identical to 76A1 and 76A2

CYP76A6      tomato
            GenEMBL ESTs only
AI779370  EST260249 cLES7J14
AI779369  EST260248 cLES7J14
AI488667  EST247006 cLED18N24
AI895030  EST264473 cLEC6H17
AI771692  EST252792 cLED34O18
AI774262  EST255457 cLER12I1 5 prime end = ARG10 homolog on reverse strand
AI779703  EST260582 cLES8J16
AI895857  EST265300 cLEC10E22
AI777873  EST258752 cLES3C24
AI777872  EST258751 cLES3C24
85% identical to 76A2
MEWELSYLFFSSIILLSIFILFFSKKNSTYNLPPGPPGLPVFGNMFELGTESYKKMA 
ALKQKYGPVLGLKVGTSTNIMVVQTAQAAAELFKNHDTSFADRPLVDVNSAHNYYQGSPA 
LARYGPFWRFQRRLCTVEMFVHKKISETVRVRRKCVDDMLKWIEKAGCSAEKGSGIEVTRFVFLASFNMLG
NLILSKDLADPESEEASEFFHAMKGIMEWSGVANVSDVFPFLRKFDLQSLRKKMTRDMGK
AMEIMSMLLKERKKGMEKMKDFLDVLLEFEGTGKDEPAKLSEHEIKVFILELFLAGTETTS
SSVEWALTELLRHPQAMAEVKTEISKAVGSNNKFEESDIENLPYMQAVIKESLRLHPPL
PFLIPRETIQDTKFMGYDVLKGTRVLVNAWAIGRDPECWDDPMSFKPERFLGSKLDVKG
QHYELIPFGARRRMCVGLPLGHRMMHFALGSLLHEFDWELPDGVSPKSINMDESMGVTA
RKRDSLKVIPKKV*

CYP76A7    Catharanthus roseus (Madagascar periwinkle)
             No accession number
             Joachim Schroeder
             54% identical to 76A4 and 76A5
             submitted to nomenclature committee Aug. 2, 2000 

76B Subfamily

CYP76B1     Helianthus tuberosus (Jerusalem artichoke)
            GenEMBL Y09920 (1742bp) Y10098 (1685bp)
            Batard,Y., LeRet,M., Schalk,M., Zimmerlin,A., Durst,F. and
            Werck-Reichhart,D.
            Molecular cloning and functional expression in yeast of CYP76B1, a
            xenobiotic-inducible 7-ethoxycoumarin O-deethylase from Helianthus
            tuberosus.
            unpublished (1997)
            CYPYAN2

CYP76B2     petunia
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee
            IMT-1

CYP76B3       Medicago sativa (alfalfa)
            no accession number
            Chris Steele
            clone TF26
            submitted to nomenclature committee

CYP76B4     Medicago sativa (alfalfa)
            no accession number
            Chris Steele
            clone A231
            submitted to nomenclature committee
            sequence below released directly from Chris Steele
            This sequence is not in Genbank (1/19/01)

>19 A231 76B4 Length: 509  July 30, 1997 Medicago sativa (alfalfa)
 
  1  MDMLQSSTLS YLVIIFTFSM LLLIKFLIPT NKTNQKNHSK LPPGPSPLPI
 51  IGNLLKLGNK PHHSLANLSN IHGPIMTLKL GQVTTIVISS ADIAKEVLQT
101  HDTLLSNRTV PDALSVLNHD QYSLSFMRVS PRWRDLRKIC NNQLFSNKTL
151  DSSQALRRRK LQDLLDDIKK CSEIDEAVDI GRVAFMTTIN LLSNTFFSAD
201  FVHSAEEAGE YKEIVVSILK EVGAPNLSDF FPMLTVFDLQ GIRRRSVVSV
251  KKVLSIFRRF VGERLKLREG TGSIENDDVL DALLNISLDD GKIEMDKDEI
301  EHLLLNIFVA GTDTTTYTLE WAMAELMHNP EIMSKVQKEL EQVVGKGIPI
351  QETDIAKLPY MQAVIKETFR LHPPVPLLLP RKAETDVEIG DYIIPKDAQV
401  LVNAWVIGRD PNKWDNANVF VPERFLDSEI DVKGHHFELI PFGSGRRICP
451  GLPLAIRMLP MMLGSLVNCF DWKLEDGLNI DDLNKEDEYG ITLEKSQPVR
501  IVPIKLTIQ

CYP76B5     petunia
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 9/26/98
            IMT-7 56% identical to 76B1, 62% identical to 76B2

CYP76B6    Catharanthus roseus (Madagascar periwinkle)
           no accession number
           G. Collu, J. Memelink and R. Verpoorte
           submitted to nomenclature committee 1/14/99
           67% identical to 76B2, 66% to 76B5, 53% with 76B3 and 76B4,  
           61% with 76B1

CYP76B7    Pastinaca sativa (wild parsnip)
           No accession number
           Art Zangerl and May Berenbaum
           See webworms and parsnips website http://www.life.uiuc.edu/berenbaum
             40% to 76A7 54% to 76B1 58% to 76B2 50% to 76B3 50% to 76B4 57% to 76B5 61% to 76B6 
             48% to 76C2 42% to 76D1 48% to 76E1 49% to 76F1 54% to 76F2 38% to 76G1 43% to 76H1 
             and 76H2 53% to 76J1
           submitted to nomenclature committee 1/29/02

76C Subfamily

CYP76C1     Arabidopsis thaliana
            GenEMBL AC003680 F17K2.9  Also D78600
            Mizutani,M., Ward,E. and Ohta,D.
            Cytochrome p450 superfamily in Arabidopsis thaliana: isolation of
            cDNAs, differential expression, and RFLP mapping of multiple
            cytochromes P450
            Plant Mol. Biol. 37, 39-52 (1998)
            P450-4

CYP76C2     Arabidopsis thaliana
            GenEMBL AC003680 F17K2.10
            ESTS H37250, T04013, T04014, T04015, T04016, T04017, Z33828, Z34697

CYP76C3     Arabidopsis thaliana
            GenEMBL AC003680 F17K2.11
            no ESTs

CYP76C4     Arabidopsis thaliana
            GenEMBL AC003680 F17K2.8

CYP76C5     Arabidopsis thaliana
            GenEMBL AC010164 93429-96444
            clone F14M2

CYP76C6     Arabidopsis thaliana
            GenEMBL AC010164 comp(88950-90642)
            clone F14M2

CYP76C7    Arabidopsis thaliana
      No accession number yet
      clone T27I15 contig 5 from European Chr. 3 project 
      contains CYP76C7 and CYP76C8P

CYP76C8P    Arabidopsis thaliana
      No accession number yet
      clone T27I15 contig 5 from European Chr. 3 project 
      contains CYP76C7 and CYP76C8P

76D Subfamily

CYP76D1     Cicer arietinum (chickpea)
            GenEMBL AB032833 (1310 bp)
            Overkamp,S., Hein,F. and Barz,W.
            Cloning and characterization of elicitor induced cytochrome P450s
            from chickpea cell suspension cultures
            Unpublished (1999)

CYP76D1     Cicer arietinum   (chickpea)
            GenEMBL AB026263
            Ichinose,Y., Tiemann,K., Schwenger-Erger,C., Toyoda,K., Hein,F.,
            Hanselle,T. and Barz,W.
            Genes Expressed in Ascochyta rabiei-Inoculated-Chickpea Plants and
            Elicited Cell Cultures as Detected by Differential
            cDNA-Hybridization
            Unpublished (1999) internal fragment from C-helix on most like 76B (35%)

CYP76E1     Medicago sativa (alfalfa)
            no accession number
            Chris Steele
            clone A11
            submitted to nomenclature committee
            sequence below released directly from Chris Steele
            This sequence is not in Genbank (1/19/01)

>22 From Chris Steele (5/15/98) alfalfa 76E1 A11
searched nr 4/1/2000
MDHQTLLLVI TFVSATILIF FLRKSNQTQN STKLPPGPYP LPIIGNILEL
GKNPHKALTK LSKIYGPIMT LKLGSITTIV ISSPQVAKQV LHDNSQIFSN
RTVPHAITAV DHDKFSVGWV PTLNLWKKLR KNCATKVFST KMLDSTKILR
QQKLQELLDY VNEKSHNGEV FDIGETVFIN VLNSISNTLF SMDLAHSTPD
EKSQEFKTII WGIMEEAGKP NISDFFPILR PLDPQGLYAR MTNHMKKLCE
IFDGIIEERI CLKDSKGDYE VCNDVLDSLL NINIGEATSE LSRNEMVHLF
LDLFVAGIDT TSSMIEWIIA ELLRNPDKLT KVRKELCQTI GKGETIEESH
ISKLPFLQAV VKETFRLHPP IPLLLPHKCD ELVNILDFNV PKNAQVLVNV
WAMGRDPAIW DNPNTFVPER FMECDINYKG NNFELIPFGA GKRICPGLPL
AHRTMHLMVA SLLHNFEWNL ADGLIPEHLN MDEQFGLTLK RVQPLRVEAI
SSA

CYP76F1     Cicer arietinum
            GenEMBL AJ249799, AJ249802
            Stefan Overkamp and Wolfgang Barz
            submitted to nomenclature committee 9/27/99
            41% to 76A1, 46% to 76B1, 44% to 76C2, 46% to 76D1, 47% to 76E1
            This sequence is identical to CYP81D9.  Both are partial sequences
            One of the names needs to be retired.  
NSARVMTLKLGQVTTVVISSADMAKEVLLTHDLITSNRTVPDAL
SVLNHDQYSLSFMRVSPRWRDLRKICNYQLFSNKTLDSSQALRRRKLQDLLNDIERCS
KVGEAVDVGKAAFKTTVNLLSNTFFSVDFVHSAKEAGEYKEIIVSILKEVGVPNVSDF
FPMLKFLDLQGIRKRSIVSVKKVLSIFKRFVGERVKMREGTGSIGNDDVLDALLNMSS
DGGKIEMDKDEIEHLLLNIFVAGTDTTTYTLEWAMAELIHNPEMMSKLKEELEKTVGK
GIPVEETDIAKLPYMQAVIKETFRLHPPVPLLLPRRAEIDVKIGDYVIPKDAQILINA
WVVGRDPTKWENPNVFIPERFLDSEIDIKGHHFELIPFGSGRRTCPGLPLAIRMLPLM
LGSLVNCFDWKLEDGLNVEDFNKEDEFGITLEKSQPVRIVPTKLY

CYP76F2     Vitis vinifera (grape)
            GenEMBL AJ237995
            Davies,C. and Robinson,S.P.
            Differential screening indicates a dramatic change in mRNA 
            Profiles during grape berry ripening. Cloning and characterization 
            of cDNAs encoding putative cell wall and stress response proteins.
            Plant Physiol. 122, 803-812 (2000)
            mRNA for putative ripening-related P-450 enzyme (gfh2 gene)
            53% identical to CYP76F1

CYP76G1     Arabidopsis thaliana
            GenEMBL AL132966
            F08J02 from the EU Chr 3 project comp(64780-66639)

CYP76H1    Triticum aestivum (wheat)
           No accession number 
           Daniele Werck-Reichhart
           Clone name 76-12 prime
           Submitted to nomenclature committee 6/4/2001
           86% to 76H2 and 76H3

CYP76H2    Triticum aestivum (wheat)
           No accession number 
           Daniele Werck-Reichhart
           Clone name 76-11
           Submitted to nomenclature committee 6/4/2001
           95% to 76H3 

CYP76H3    Triticum aestivum (wheat)
           No accession number 
           Daniele Werck-Reichhart
           Clone name 76-17a
           Submitted to nomenclature committee 6/4/2001
           95% to 76H2, 36% to 76A6, 41% to 76B4, 45% to 76C2, 
           41% to 76D1 partial seq, 40% to 76E1, 46% to 76F2, 39% to 76G1

CYP76J1     Petunia
            no accession number
            Hiromasa Imaishi
            submitted to nomenclature committee 7/24/98
            clone IMT-8 

77A Subfamily

CYP77A1     Solanum melongena cv. Sinsadoharanasu (eggplant)
            GenEMBL X71656 (1683bp) Swiss P37123 (499 amino acids)
            PIR S41599 S40267 (499 amino acids)
            Toguri,T. and Tokugawa,K.
            Cloning of eggplant hypocotyl cDNAs encoding cytochrome P450
            belonging to a novel family (CYP77)
            FEBS Lett. 338, 290-294 (1994)
            Note: clone name H1

CYP77A2     Solanum melongena cv. Sinsadoharanasu (eggplant)
            GenEMBL X71655 (1673bp) Swiss P37124 (511 amino acids)
            PIR S41598 S40266 (511 amino acids)
            Toguri,T. and Tokugawa,K.
            Cloning of eggplant hypocotyl cDNAs encoding cytochrome P450
            belonging to a novel family (CYP77)
            FEBS Lett. 338, 290-294 (1994)
            Note: clone name H2

CYP77A3     Glycine max (soybean)
            GenEMBL AF022464 (1644bp)
            Siminszky,B., Dewey,R.E. and Corbin,F.T.
            clone name 6/10

CYP77A4     Arabidopsis thaliana
            GenEMBL B97241
            GSS fragment BAC end T32M21TR
            note: contains N-terminal 65% identical to 77A3
            No ESTs

CYP77A5P    Arabidopsis thaliana
            GenEMBL AP000414 13981-14298 fragment
            65% identical to 77A2 with an in frame stop codon and 
            several frameshifts in the PERF to heme region
            identical match to EST H36337 clone 178A11T7
            opposite end = AA651240 clone 178A11XP 3', mRNA sequence
            matches AP00414 from 16129-16750 = 3 prime UTR

CYP77A6     Arabidopsis thaliana
            GenEMBL AC011560 71181-72725 clone F13M14 also on AC013428
            No introns

CYP77A7     Arabidopsis thaliana
            GenEMBL AC011560 72998-74939 clone F13M14 also on AC013428
            No introns

CYP77A8P    Arabidopsis thaliana
            GenEMBL AB010077 
            Pseudogene fragments
            51066-51110 (26-40), 56196-56252 (167-185), 
            56264-56377 (195-232), 75123-75146 (233-240)

CYP77B1     Arabidopsis thaliana
            GenEMBL AC007296 comp(89516-91048) 
            45% to 77A3 sequences no introns 
            ESTs Z30775, Z30776 noGSSs

78A Subfamily

CYP78A1     Zea mays (maize)
            GenEMBL L23209 (2087bp)
            Larkin,J.C.
            Isolation of a cytochrome P450 homologue preferentially expressed
            in developing inflorescences of Zea mays L
            Unpublished (1993)

CYP78A2      Phalaenopsis sp. hybrid SM9108 (moth orchid)
            GenEMBL U34744 (1799bp)
            Nadeau,J.A., Zhang,X., Li,J. and O'Neill,S.D.
            Molecular Characterization of Ovule Development: Isolation of
            Stage- and Tissue-specific cDNAs.
            unpublished (1995)

CYP78A3      Glycine max (soybean)
            GenEMBL AF022463 (1611bp)
            Siminszky,B., Dewey,R.E. and Corbin,F.T.
            clone name 6/4

CYP78A4     Pinus radiata (Monterey pine)
            GenEMBL AF049067
            Bishop-Hurley,S.L., Walter,C. and Gardner,R.C.
            Isolation and Expression of Abundant mRNAs during Somatic
            Embryogenesis of Pinus radiata
            Unpublished

CYP78A5    Arabidopsis
           GenEMBL AC027656 comp(32530-34190)
           Susan Carr Zondlo
           submitted to nomenclature committee Sept. 22, 1998
           58% identical to 78A2
           EST T45256

CYP78A6      Arabidopsis thaliana
           GenEMBL AC005819 AC006418
           65% identical to 78A3

CYP78A7      Arabidopsis thaliana
           GenEMBL AC016893
           59% identical to 78A4 and 78A1

CYP78A8     Arabidopsis thaliana
            GenEMBL AC007323 comp(15232-17051) 
            62% identical to 78A6 
            no ESTs no GSSs

CYP78A9     Arabidopsis thaliana
            GenEMBL AB036059
            Toshiro Ito
            submitted to nomenclature committee 9/9/99
            81% identical to 78A6
            EST AI995549 no GSSs

CYP78A9     Arabidopsis thaliana
            GenEMBL AB036059
            contig 31 of clone F21F14 from the EU chr 3 project 
            8955-10728 numbering will change as contigs are joined 
            (formerly confidential)

CYP78A9     Arabidopsis thaliana
            GenEMBL AL138642 (chr 3 F21F14)

CYP78A10    Arabidopsis thaliana
            GenEMBL AC016662

CYP78A11    Oryza sativa (rice)
            GenEMBL AC083943.6  25-JUL-2001
            clone OSJNBa0044A10, 61% to 78A7
            also submitted by Ahn Byoung-Ohg and N. Kurata 10/31/2001
40753 MAMATATASSCVDATWWAYALPALLGADTLCAHPALLAGAVLLAFATAAVLAWAASPGGPAWAHGRGRLGA 40965
40966 TPIEGPRGLPVFGSIFALSRGLPHRALDAMSRDAAAPRARELMAFSVGETPAVVSSCPAT 41145
41146 AREVLAHPSFADRPLKRSARELLFARAIGFAPSGEYWRLLRRIASTHLFSPRRVAAHEPG 41325
41326 RQADATAMLSAMAAEQSATGAVVLRPHLQAAALNNIMGSVFGRRYDVSSSSGAAADEAEQ 41505
41506 LKSMVREGFELLGAFNWSDHLPWLAHLYDPNHVARRCAALVPRVQAFVRGVIRDHRLRRD 41685
41686 SSSTAADNADFVDVLLSLEAHENLAEDDMVAVLW 41787 (phase 0 intron)
41874 EMIFRGTDTTALVTEWCMAEVVRNPAVQARLRAEVDAAVGGDGCPSDGDVARMP 42035
42036 YLQAVVKETLRAHPPGPLLSWARLATADVGLANGMVVPAGTTAMVNMWAITHDGEVWADP 42215
42216 EAFAPERFIPSEGGADVDVRGGDLRLAPFGAGRRVCPGKNLGLATVTLWVARLVHAFDWF 42395
42396 LPDGSPPVSLDEVLKLSLEMKTPLAAAATPRRRRAA* 42506



79A Subfamily

CYP79A1     Sorghum bicolor
            GenEMBL U32624 
            Koch, B.M., Sibbessen, O., Halkier, B.A., Svendsen, I. and Lindberg Moller, B.
            Arch. Biochem. Biophys. 323, 177-186 (1995)

CYP79A2      Arabidopsis thaliana (thale cress)
             GenEMBL AB010692 comp(11000-13200 region)
             about 53% identical to 79A1
             Note: this sequence was included in 79A when there was only one
             other CYP79A sequence.  Now that there are several, this sequence
             does not really fit well in the CYP79A subfamily.  However, the
             name will remain the same for historical reasons.

CYP79A3P     Arabidopsis thaliana
             GenEMBL AB025602 14755-16760 
             Stop codon in Heme signature and frameshifts at K-helix and after
             Heme signature. Probable pseudogene but alternative C-terminal lies beyond.
             88% identical to 79A2

CYP79A4P     Arabidopsis thaliana
             GenEMBL AB025602 22090-22536
             Lone C-terminal exon.  Note: this exon may join with N-terminal exons of 
             CYP79A3P to make a complete P450 gene.  The natural last exon my be skipped. 
             same as GSS B61504

CYP79A5     Triticum aestivum (wheat)
            No accession number
            Daniele Werck-Reichhart
            58% to 79A1
            clone name 79A14
            submitted to nomenclature committee July 18, 2000 

CYP79A6     Triticum aestivum (wheat)
            No accession number
            Daniele Werck-Reichhart
            96% to 79A5
            clone name 79A1
            submitted to nomenclature committee July 18, 2000 

CYP79A7     Oryza sativa (rice)
            GenEMBL AC084319.5
               complement(join(117988..118644,121556..122530))
               also AC091302.3
               58% to 79A1
MSEAMAVTMPPMRAPALVAMLVVVLVALVRRRRHRSKGAGGRLESLPP
GPVGLPVIGNMHQMLVNKPVFRWVHRLLADAGGEIVCVRLGPVHVVAVTSPEMAREVL
RKNDAVFADRPTTFAAESFSVGYRSASISPHGDQWRKMRRVLTAEILSPATEHRLRGA
RGEEADHLVRYVLVRCGRDGAAVDVRHVARHFCGNVIRRLTLGRRHFREPRADDEDAA
APGRDEAEHVDALFATLNYLDAFCVSDYFPALVGLDLDGQEKVIKKVMRTLNRLHDPV
VEERVEEWRLLRKAGERRDVADFLDVLASLDDAAGRPLLTVEEIKAQTIDIMIATVDN
PSNAVEWALAEMMNKPEVMRKAMDELDTVVGRDRLVQESDVRDLNYLKACIREAFRLH
PYHPFNPPRVAMADTTIAGYTIPKGSQVILSRVGLGRNPRVWDDPLEFRPERHLSPYP
AGGRGDAGVVALTEAELRFVSFSTGRRGCPGVSLGTLITVTLFARLLQGFEWSKPAGV
ERVELREEAASLVLAQPLVLQATPRLAAHLYGAGK

CYP79A8     Hordeum vulgare (barley)
            No accession number
            Soren Bak and Katrine Pontoppidan
            Submitted to nomenclature committee 4/9/02

CYP79A9     rice
            See rice pages

CYP79A10    rice
            See rice pages

CYP79A11    rice
            See rice pages

CYP79A12    Hordeum vulgare (barley)
            No accession number
            Kirsten Nielsen
            Submitted to nomenclature committee 5/21/03

79B Subfamily

CYP79B1     Sinapis alba (white mustard)
            GenEMBL AF069494 (1886 bp)
            Bak,S., Nielsen,H.L. and Halkier,B.A.
            The presence of CYP79 homologues in glucosinolate-producing plants
            shows evolutionary conservation of the enzymes in the conversion of
            amino acids to aldoximes in the biosynthesis of cyanogenic
            glucosides and glucosinolates.
            Plant Mol. Biol. 38, 725-734 (1998) 

CYP79B2     Arabidopsis thaliana (thale cress)
            GenEMBL AF069495 (1370 bp) AL035708 T5J17.120 complete sequence 
            Bak,S., Nielsen,H.L. and Halkier,B.A.
            The presence of CYP79 homologues in glucosinolate-producing plants
            shows evolutionary conservation of the enzymes in the conversion of
            amino acids to aldoximes in the biosynthesis of cyanogenic
            glucosides and glucosinolates.
            Plant Mol. Biol. 38, 725-734 (1998) 
            ESTs T42902 from C-helix on
            Contig 1510 of the TIGR Landsberg erecta sequences has 99% match

            Hull, A.K., Vij, R. and Celenza, J.L. (2000) 
            Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent 
            Indole-3-acetic acid biosynthesis.
            PNAS Early Edition (preprint)
            Converts trp to indole-3-acetic acetaldoxime (IAOx)

CYP79B3    Arabidopsis
            GenEMBL AC006592 comp(103303-105685) also AC007168 76873-79255
            85% identical to 79B2
            no ESTs no GSSs

            Hull, A.K., Vij, R. and Celenza, J.L. (2000) 
            Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent 
            Indole-3-acetic acid biosynthesis.
            PNAS Early Edition (preprint)
            Converts trp to indole-3-acetic acetaldoxime (IAOx)

CYP79B4P      Arabidopsis
            GenEMBL AC006592 comp(101836-101952) and comp(102489-102605)
            also AC007168 79953-80069 and 80606-80722 clone T26C19
            lone exons at C-terminal

CYP79B5     rape
            No accession number
            Barbara Halkier
            Submitted to nomenclature committee 6/7/00
       %identity (aa level) to other CYP79s is: 44.1 to E1, 44.1 to E2, 
       50.8 to D1, 51.4 to D2, 95.9 to B1, 93.5 to B2, 85.3 to B3, 
       52.0 to A1, 48.4 to A2, 38.4 to F1, 38.4 to F2, 41.0 to C1.

79C Subfamily

CYP79C1      Arabidopsis thaliana (thale cress)
            GenEMBL AC002986 comp(75-1680) AC007202 comp(77381-79610)
            C-terminal missing from AC002986.  Intron sequence after PKG runs off the end
            of the DNA on the complementary strand.  AC007202 complete
            Contig 505 and 1241 of the TIGR Landsberg erecta sequences have 100% matches

CYP79C2     Arabidopsis thaliana (thale cress)
            GenEMBL AC008051 1899-4148
            this gene has four frameshifts in a preliminary version of the sequence.  It may be a    
            pseudogene there are three pseudogene fragments associated with it CYP79C3P, 
            CYP79C4P and CYP79C5P
            chromosome 1, 52% to 79C1

CYP79C3P    Arabidopsis thaliana (thale cress)
            GenEMBL AC008051 5709-6541

CYP79C4P    Arabidopsis thaliana (thale cress)
            GenEMBL AC008051 7210-7435

CYP79C5P    Arabidopsis thaliana (thale cress)
            GenEMBL AC008051 9049-9895

79D Subfamily

CYP79D1     Manihot esculenta (cassava)
            GenEMBL AF140613
            Mette Dahl Andersen
            submitted to nomenclature committee
            clone val152

CYP79D2     Manihot esculenta (cassava)
            GenEMBL AF140614
            Mette Dahl Andersen
            submitted to nomenclature committee
            clone val211

CYP79D3     Lotus japonicus
            No accession number
            Soren Bak
            submitted to nomenclature committee Feb. 7, 2003
            clone name sequence 1

CYP79D4     Lotus japonicus
            No accession number
            Soren Bak
            submitted to nomenclature committee Feb. 7, 2003
            clone name sequence 2

79E Subfamily

CYP79E1       Triglochin maritima
            GenEMBL AF140609
            Nielsen,J.S. and Moller,B.L.
            Cloning and expression of cytochrome P450 enzymes catalyzing the
            conversion of tyrosine to p-hydroxyphenylacetaldoxime in the
            biosynthesis of cyanogenic glucosides in Triglochin maritima
            Plant Physiol. 122 (4), 1311-1321 (2000)
            clone tri 361

CYP79E2       Triglochin maritima
            GenEMBL AF140610
            Nielsen,J.S. and Moller,B.L.
            Cloning and expression of cytochrome P450 enzymes catalyzing the
            conversion of tyrosine to p-hydroxyphenylacetaldoxime in the
            biosynthesis of cyanogenic glucosides in Triglochin maritima
            Plant Physiol. 122 (4), 1311-1321 (2000)
            submitted to nomenclature committee 3/26/99
            95% identical to CYP79E1

CYP79F1     Arabidopsis thaliana
          GenEMBL AC006341 comp(63874-66127)
          46% identical to 79C1 less with other 79s
          ESTs F14189, F14190

CYP79F2     Arabidopsis thaliana
          GenEMBL AC006341 comp(60246-62290)
          89% identical to 79F1 no ESTs 98% identical to GSS B20058

80A Subfamily

CYP80A1       Berberis stolonifera
            GenEMBL U09610 
            Kraus.P.F.X. and Kutchan,T.M.
            Molecular cloning and heterologous expression of a cDNA encoding
            berbamunine synthase, a C-O phenol-coupling cytochrome P450
            from the higher plant Berberis stolonifera.      
            unpublished (1994)
            submitted to nomenclature committee

80B Subfamily

CYP80B1v1      Eschscholzia californica (California poppy)
            GenEMBL AF014800 (1901bp)
            Pauli,H.H. and Kutchan,T.M.
            Molecular cloning and functional heterologous expression of two
            alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a
            new methyl jasmonate-inducible cytochrome P-450-dependent
            monooxygenase of benzylisoquinoline alkaloid biosynthesis
            Plant J. 13, 793-801 (1998)
            HP1
            41.8% identical to 80A1

CYP80B1v2      Eschscholzia californica (California poppy)
            GenEMBL AF014801 (1613bp)
            Pauli,H.H. and Kutchan,T.M.
            Molecular cloning and functional heterologous expression of two
            alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a
            new methyl jasmonate-inducible cytochrome P-450-dependent
            monooxygenase of benzylisoquinoline alkaloid biosynthesis
            Plant J. 13, 793-801 (1998)
            HP3
            99% identical to 80B1v1 possible allele

CYP80B2          Coptis japonica (Japanese goldthread)
           no accession number 
           Fumihiko Sato
           Submitted to nomenclature committee 3/21/99
           70% identical to CYP80B1
           clone name CYPCJA

CYP80B3    Papaver somniferum (opium poppy)
           GenEMBL AF191772
           Facchini,P.J. and Yu,M.
           cDNA cloning and characterization of (S)-N-methylcoclaurine
           3'-hydroxylase (CYP80B1) from elicitor-treated opium poppy cell
           suspension cultures
           Unpublished

81A Subfamily


Note: The 81 and 91 families have been joined due to new Arabidpsis sequences that have 
strong sequence identity to both families.  The CYP91 family sequences have been 
renamed with new CYP81 family names.  The old names will still be recognized, but the 
newer names will be preferred.

CYP81A1     Zea mays
            Sharon Potter
            sequence g 
            submitted to nomenclature committee

CYP81A2     Zea mays
            Sharon Potter
            sequence h
            submitted to nomenclature committee

CYP81A3     Zea mays
            Sharon Potter
            sequence i
            submitted to nomenclature committee

CYP81A4     Zea mays
            Sharon Potter
            sequence k
            submitted to nomenclature committee
            ESTs AI920363 (100% match) AI947634 (1 amino acid difference)

81B Subfamily

CYP81B1v1     Helianthus tuberosus (Jerusalem artichoke)
            GenEMBL AJ000477
            Cabello-Hurtado,F., Batard,Y., Salaun,J.P., Durst,F., Pinot,F. and
            Werck-Reichhart,D.
            Cloning, expression in yeast, and functional characterization of
            CYP81B1, a plant cytochrome P450 that catalyzes In-chain
            hydroxylation of fatty acids
            J. Biol. Chem. 273, 7260-7267 (1998)
            CYPYAN also called CYP81B1c

CYP81B1v2     Helianthus tuberosus (Jerusalem artichoke)
            GenEMBL AJ000478
            Cabello-Hurtado,F., Batard,Y., Salaun,J.P., Durst,F., Pinot,F. and
            Werck-Reichhart,D.
            Cloning, expression in yeast, and functional characterization of
            CYP81B1, a plant cytochrome P450 that catalyzes In-chain
            hydroxylation of fatty acids
            J. Biol. Chem. 273, 7260-7267 (1998)
            also called CYP81B1l

CYP81B2       tobacco
            no accession number 
            Yamada
            tobacco sequence 1
            submitted to nomenclature committee

CYP81B       Oryza sativa (rice)
           GenEMBL AF140486 partial sequence
           57% to 81B1v1 over C-terminal fragment

81C Subfamily

CYP81C1       tobacco
            no accession number 
            Yamada
            tobacco sequence 3
            submitted to nomenclature committee

CYP81C2       tobacco
            no accession number 
            Yamada
            tobacco sequence 4
            submitted to nomenclature committee

81D Subfamily

CYP81D1 formerly CYP91A1 (families joined)
            Arabidopsis thaliana
            D78606 (500 amino acids)
            Mizutani,M., Ward,E. and Ohta,D.
            Cytochrome p450 superfamily in Arabidopsis thaliana: isolation of
            cDNAs, differential expression, and RFLP mapping of multiple
            cytochromes P450
            Plant Mol. Biol. 37, 39-52 (1998)
            P450-65

CYP81D1     Arabidopsis thaliana 
            GenEMBL AB026661 comp(8484-10672)

CYP81D2     Arabidopsis thaliana
            GenEMBL Z99707 C7A10.10 C-terminal fragment 
            AL035601 F6G17.10  complete sequence 
            GSS AQ250603

CYP81D2     Arabidopsis thaliana
            GenEMBL AL161591 possibly 9 genes
            complement(join(60895..61509,61614..62000,62132..62629))

CYP81D3     Arabidopsis thaliana
            GenEMBL Z99707 C7A10.20
            Complete sequence 

CYP81D3     Arabidopsis thaliana
            GenEMBL AL161591 possibly 9 genes
            CDS complement(join(58723..59340,59438..59824,59979..60476))

CYP81D4     Arabidopsis thaliana
            GenEMBL Z99707 C7A10.30
            Complete sequence 

CYP81D4     Arabidopsis thaliana
            GenEMBL AL161591 possibly 9 genes
            complement(join(56317..56919,56990..57364,57839..58339))

CYP81D5     Arabidopsis thaliana
            GenEMBL Z99707 C7A10.40
            Complete sequence

CYP81D5     Arabidopsis thaliana
            GenEMBL AL161591 possibly 9 genes
            CDS complement(join(53512..54114,54191..54574,54960..55460))
 
CYP81D6     Arabidopsis thaliana
            GenEMBL AC002391 T20D16.15
            Complete sequence 

CYP81D7        Arabidopsis thaliana
            GenEMBL AC002391 T20D16.18
            Complete sequence 

CYP81D8 formerly CYP91A3 (families joined)
            Arabidopsis thaliana
            GenEMBL AL035601 F6G17.20
            65% identical with 81D1
            ESTs AA586064, N38687, T41596, H76015

CYP81D8 formerly CYP91A3 (families joined)
            GenEMBL AL161591 possibly 9 genes
            complement(join(63742..64353,64451..64834,64952..65449))

CYP81D9X   Cicer arietinum (chickpea)
           GenEMBL AJ249802
           Stefan Overkamp
           submitted to nomenclature committee 4/28/99
           60% identical to 81D8 over J-helix to end of gene
           Note: 81D9 and 76F1 seem to be the same sequence
           One of the names must be discontinued.  This seq is partial
           And this reflects the difficulties of assigning a name to a partial 
           sequence.  The best match to 81D9 is a grape P450 AJ237995
           the grape seq seems to belong to the 76 family, so 76F1 is correct
           This is a problem I should have caught, but missed.
PPVEETDIAKLPYMQAVIKETFRLHPPVPLLLPRRAEIDVKIGD
YVIPKDAQILINAWVVGRDPTKWENPNVFIPERFLDSEIDIKGHHFELIPFGSGRRTC
PGLPLAIRMLPLMLGSLVNCFDWKLEDGLNVEDFNKEDEFGITLEKSQPVRIVQLNCI
ENMFRLLQFMRR

CYP81D10   Arabidopsis thaliana
           GenEMBL AC013288 14837-27604 clone T12I7
           74% to 81D2 chromosome I 
           GSSs B23310 B21261 no ESTs

CYP81D11   Arabidopsis thaliana
           GenEMBL AP002057 comp(8441-10208)
           chromosome 3, BAC clone T19N8, 67% to 81D2
           ESTs T14177 Z29010, Z29011, Z26103, H77232, F14118

81E Subfamily

CYP81E1 formerly CYP91A4 (families joined)
            Glycyrrhiza echinata_ L. (licorice; Fabaceae)
            GenEMBL AB001379  or D89431
            Akashi,T., Aoki,T., Kameya,N., Nakamura,I. and Ayabe,S.
            Two new cytochrome P450 cDNAs (Accession Nos. AB001379 and
            AB001380) from elicitor-induced licorice (Glycyrrhiza echinata L.)
            cells (PGR97-167)
            Plant Physiol. 115, 1288 (1997)            Ge-3
            50.1% identical to 81D1

            Akashi, T., Aoki, T. and Ayabe, S. 
            CYP81E1, a cytochrome P450 cDNA of licorice (Glycyrrhiza echinata L.)
            encodes isoflavone 2'-hydroxylase.
            Biochem. Biophys. Res. Commun. 251, 67-70 (1998)

CYP81E1v2      Glycyrrhiza echinata
            GenEMBL   AB022732
            Akashi,T., Aoki,T. and Ayabe,S.
            A cytochrome P450 cDNA from cultured Glycyrrhiza echinata L. cells
            unpublished (1999) In press
            CYP Ge-31 97% identical to CYP81E1
MDILSLLSYSVFYLALFFIFNIVIRARKFKNLPPGPPSLPIIGN
LHHLKRPLHRTFKGLSEKYGHVISLWFGSRLVVVVSSASEFQQCFTKNDVVLANRPRF
LSGKYIFYNYTTLGSTSYGEHWRNLRRITALDVLSNHRINSFSGIRRDETQRLITRLA
DDSSTNFAEIELSYRFYDMTFNNIMRMISGKRYYGEDCDMSDLQEASQFRDMVSELLQ
LSGANNKTDFMPLLRFLDFENLEKRLKDISGKTDAFLRGLIQEHRAKKERANTMIDHL
LNLQDSQPEYYTDQIIKGLALAMLLAGTDSSAVTLEWSMSNLLNHPEVLKKVKDELDT
HVGQDRLVDESDLPKLSYLKNVINETLRLYTPAPLLLPHSTSDECNIGGYKVPQDTIV
LINAWAIHRDPELWTEATTFKPERFEKKGELEKLIAFGMGRRACPGEGLAIRAISMTL
ALLIQCFDWKLTNGDKIDMAERDGFTLTKLVPLKAMCKSRPVINKVFKQ

CYP81E2 formerly CYP91A5 
            Cicer arietinum (chickpea)
            GenEMBL AJ239051
            Overkamp,S., Hein,F. and Barz,W.
            Isolation of elicitor induced cytochrome P450 sequences from
            chickpea (Cicer arietinum) cell suspension cultures
            Unpublished
            submitted to nomenclature committee, sequence revised 5/20/99
            52.7% identical to CYP81E1

CYP81E3v1       Cicer arietinum (chickpea)
            GenEMBL AJ012581
            Stefan Overkamp and Wolfgang Barz
            Cloning of Two Cicer arietinum L.
            cDNA's (Accession Nos. AJ012581 and AJ238439) Encoding Cytochrome P450s 
            Highly Homologous to Isoflavone 2'-Hydroxylase from Licorice. (PGR99-102)
            Plant Physiol. 120, 935 (1999)
            86% identical to CYP81E1 from licorice

CYP81E3v2       Cicer arietinum (chickpea)
            GenEMBL AJ238439
            Stefan Overkamp and Wolfgang Barz
            Cloning of Two Cicer arietinum L.
            cDNA's (Accession Nos. AJ012581 and AJ238439) Encoding Cytochrome P450s 
            Highly Homologous to Isoflavone 2'-Hydroxylase from Licorice. (PGR99-102)
            Plant Physiol. 120, 935 (1999)
            (revised sequence sent 4/28/99)
            85% identical to CYP81E1 from licorice
            96% identical to 81E3v1 (6 amino acid differences in N-terminal 20 amino acids)

CYP81E4     Cicer arietinum (chickpea)
            GenEMBL AJ249801
            Stefan Overkamp 
            62% identical to 81E1 from I-helix to end of gene
            84% identical to 81E5
            submitted to nomenclature committee 8/17/99 revised 9/6/99
IRHEIQAMLLAGTDTSAVTIEWVMSELLNHPDVLKQSKRRNRTQ
IGKDKLIEEHDLSKLPYLQNIINETLRLHPPAPLSLPHYSSEDFTLGGFNVPKDTIIL
TNVWAIHRDPKYWSDASSFKPERFEIDGELNKLIAFGLGRRACPGQSLAHRTVGLTLG
LLIQCFEWKRETEEKIDLREGKGLTMPMGVPLKAMCKPLPIANYIIS

CYP81E5         Cicer arietinum (chickpea)
            GenEMBL AJ249800
            Stefan Overkamp 
            submitted to nomenclature committee 9/16/99
            84% identical to 81E4

CYP81E6     Lotus japonicus
            GenEMBL AB025016
            Shimada,N., Aoki,T. and Ayabe,S.
            A cytochrome P450 cDNA from Lotus japonicus
            Unpublished April 4, 2000

CYP81E7     Medicago truncatula (barrel medic)
            No accession
            Chang-Jun Liu
            submitted to nomenclature committee 3/10/2003
            clone name MtCYP81E1V2
            84% to 81E1v2
            

CYP81E8     Medicago truncatula (barrel medic)
            No accession
            Chang-Jun Liu
            submitted to nomenclature committee 3/10/2003
            clone name MtCYP81E2
            62% to 81E1v2 60% to 81E2
            

CYP81E9     Medicago truncatula (barrel medic)
            No accession
            Chang-Jun Liu
            submitted to nomenclature committee 3/10/2003
            clone name MtCYP81E3
            61% to 81E1v2 63% to 81E3v1

81F Subfamily

CYP81F1 formerly CYP91A2 (families joined)
            Arabidopsis thaliana
            D78607 (500 amino acids) also AL035601 F6G17.80
            Mizutani,M., Ward,E. and Ohta,D.
            Cytochrome p450 superfamily in Arabidopsis thaliana: isolation of
            cDNAs, differential expression, and RFLP mapping of multiple
            cytochromes P450
            Plant Mol. Biol. 37, 39-52 (1998)
            P450-66-8

CYP81F2     Arabidopsis thaliana
            GenEMBL AB019233 11949 - 13701
            about 70% identical to 81F1

CYP81F3    Arabidopsis
           GemEMBL AL035601 F6G17.50 
           ESTs AA712784
           68% identical to 81F1

CYP81F3     Arabidopsis thaliana
            GenEMBL AL161591 possibly 9 genes
            CDS join(78416..78736,78839..78898,79333..79968) partial

CYP81F4    Arabidopsis
           GemEMBL AL035601 F6G17.60 
           ESTs T46441 AA598000 AI099973 
           65% identical to 81F2

CYP81F4    Arabidopsis
           AL161591 possibly 9 genes
           CDS join(84619..85494,85922..86551)

81G Subfamily

CYP81G1        Arabidopsis thaliana
            GenEMBL AB007645 (comp. 8707-7177)
            Complete sequence 

81H Subfamily

CYP81H1       Arabidopsis thaliana
              GenEMBL Z99707 C7A10.50
              Complete sequence

CYP81H1       Arabidopsis thaliana
              GenEMBL AL161591 possibly 9 genes
              CDS complement(join(49922..50578,51085..51474,52094..52603))

CYP81J1 formerly CYP717A1       Hemerocallis hybrid cultivar (daylily)
             GenEMBL AF082028 (1373bp)
             Panavas,T., Pikula,A., Reid,P.D., Rubinstein,B. and Walker,E.L.
             Identification of senescence-associated genes from daylily
             Unpublished
STEIFSPVRIRSLAAVRQEEVKLMITGILASTSTDNSVKVNMKV
VFSELMFNVIMKIIAGKRYFGVNTDSEVEEGQKFRVVFDEMFSTLEVASPQDFLPFLK
WFGFKRMENRLTKLAKELDQLFQKLIEERRSERGKVQSTVIDVLLSLQETDREQYSDK
LIKGMILSLIAAGTHTTAGTMEWAMSLLLNHPEALLKVRDEIDKKVGQDRLIDHSDLQ
NLSYLNNAIKESLRLFPTAPLLLAHESSAECTVGGFTIPSNTILFANAYALHRDPKVW
TDPVSFKPERFENNGQQGSRIYVPFGLGRRSCPGEGLATQVVGLALGTLIQCFEWDRN
GEEKVDMTDGSGLAMHMEKPLEAMCKPRQSIVDVINRL

CYP81K1     Arabidopsis thaliana
           GenEMBL AL353995 comp(9841..11343)
           chromosome 5, BAC clone F12B17

CYP81L1    Triticum aestivum (wheat)
           No accession number 
           Daniele Werck-Reichhart
           Clone name 81-1
           Submitted to nomenclature committee 6/4/2001
           45% to 81A2, 48% to 81B1, 40% to 81C1, 46% to 81D10
           40% to 81E1v2, 39% to 81F1, 41% to 81G1, 40% to 81H1
           43% to 81J1 partial, 38% to 81K1

CYP81K2     Arabidopsis thaliana
           GenEMBL AL353995 comp(11529..11633,11733..11837,12108..13583)
           chromosome 5, BAC clone F12B17
           note: this sequence has a C-terminal extension that may be incorrect

82A Subfamily

CYP82A1       Pisum sativum (pea)
            GenEMBL U29333 (1763bp)
            Frank,M.R., Deyneka,J.M. and Schuler,M.A.
            Cloning of phenylpropanoid pathway P450 monooxygenases expressed in
            Pisum sativum.
            unpublished

CYP82A2      Glycine max (soybean)
            GenEMBL Y10491 (1757bp)
            Schopfer,C.R. and Ebel,J.
            Identification of elicitor-induced cytochrome P450s of soybean
            (Glycine max L.) using differential display of mRNA
            Mol. Gen. Genet. 258, 315-322 (1998)
            clone CP4

CYP82A3      Glycine max (soybean)
            GenEMBL Y10982 (1798bp)
            Schopfer,C.R. and Ebel,J.
            Identification of elicitor-induced cytochrome P450s of soybean
            (Glycine max L.) using differential display of mRNA
            Mol. Gen. Genet. 258, 315-322 (1998)
            clone CP6

CYP82A4      Glycine max (soybean)
            GenEMBL Y10983 (1818bp)
            Identification of elicitor-induced cytochrome P450s of soybean
            (Glycine max L.) using differential display of mRNA
            Mol. Gen. Genet. 258, 315-322 (1998)
            clone CP9

82B Subfamily

CYP82B1       Eschscholzia californica (California poppy)
            GenEMBL AF014802 (1915bp)
            Pauli,H.H. and Kutchan,T.M.
            Molecular cloning and functional heterologous expression of two
            alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a
            new methyl jasmonate-inducible cytochrome P-450-dependent
            monooxygenase of benzylisoquinoline alkaloid biosynthesis
            Plant J. 13, 793-801 (1998)
            HP2
            43.8% identical to 82A3
            (S)-N-methylcoclaurine 3'-hydroxylase

82C Subfamily

CYP82C1      Glycine max (soybean)
            GenEMBL AF022461 (1788bp)
            Siminszky,B., Dewey,R.E. and Corbin,F.T.
            clone name 6/2

CYP82C2 Arabidopsis thaliana
            GenEMBL AL021636 
            F10N7.200  comp(74899-76846)
            GenEMBL AL049607 89014-90961
            Contig 404 of the TIGR Landsberg erecta sequences has 100% match

CYP82C3 Arabidopsis thaliana
            GenEMBL AL021636 
            F10N7.220  comp(82167-84090)
            GenEMBL AL049607 81769-83693

CYP82C4 Arabidopsis thaliana
            GenEMBL AL021636 
            F10N7.230  comp(85290-87213)
            GenEMBL AL049607 78646-80569

82D Subfamily

CYP82D1     Medicago sativa (alfalfa)
            no accession number
            Chris Steele
            clone A48
            submitted to nomenclature committee
            sequence below released directly from Chris Steele
            This sequence is not in Genbank (1/19/01)
>30 C Steele, July 30, 1997 13:45. A48 82D1 Medicago sativa (alfalfa)

  1  MDVTIEYLYT IVAGVICIIL ISYSKFFRGD ARAQPKLPPL ASGGWPLIGH
 51  LHLLGSSNQP PYITLGNLAD KYGPIFTLRV GVHNAVVVST WELAKEIFTT
101  HDVIISSRPK FTAAKILGHD YANFGFSPYG DYWQMMRKVT ASELLSTRRF
151  ETLRDIRDSE VKKSLMELCN SGFDGDLKVE MKRFLGDMNL NVIMRMIAGK
201  RYSNNESGDE REVRKVRWVF REFFRLTGLF VVGDAIPFLG WLDLGGHVKE
251  MKKAAREMDS VVCGWLEDHR HKNVIGETKM EQDFIDVLLS VLHGVHLDGY
301  DVDTVIKATC LTLIAGATDT TTVTITWALS LLLNNRHTLK KVQDELDEKV
351  GKDRLVNESD INNLVYLQAV VKETLRLYPA GPLSGARQFT KDCTVGGYNI
401  RAGTRLILNL WKMHRDPRVW SEPLEFQPER FLNTHKDVDV KGQHYELLPF
451  GGGRRSCPGI TFGLQMTNLA LASFLQAFEV TTPSNAQVDM SATFGLTNIK
501  TTPLEVIAKP RLPYHLLFVK EH

82E Subfamily

CYP82E1    Nicotiana tabacum   (tobacco)
           GenEMBL AB015762 (1727bp)
           Takemoto,D. and Kawakita,K.
           Putative cytochrome P450 gene from tobacco induced by fungal
           elicitor treatment
           unpublished (1998)

82F Subfamily

CYP82F1           Arabidopsis thaliana
           GenEMBL AL031369
           50% identical to 82C1, 43-44% with other 82C sequences
           complement(join(52551..52924,53217..53496,53597..54526))
           gene="F13D4.120" same gene as B29081 GSS fragment

CYP82G1     Arabidopsis thaliana
           GenEMBL AB026647 comp(36473-38300)
           46% identical to 82C1 and less with other subfamilies in CYP82

83A Subfamily

CYP83A1     Arabidopsis thaliana
            GenEMBL U18929 (1551bp)
            Clint Chappel
            A cDNA encoding a novel cytochrome p450-dependent monooxygenase 
            from Arabidopsis thaliana.
            Plant Physiol. 108, 875-876 (1995)
            clone pCC19
            Additional EST fragment: T88085

CYP83A1     Arabidopsis thaliana
            D78599 (502 amino acids)
            Mizutani,M., Ward,E. and Ohta,D.
            Cytochrome p450 superfamily in Arabidopsis thaliana: isolation of
            cDNAs, differential expression, and RFLP mapping of multiple
            cytochromes P450
            Plant Mol. Biol. 37, 39-52 (1998)
            P450-3

CYP83A1     Arabidopsis thaliana
            GenEMBL U69134
            Pierre Bilodeau
            genomic sequence (one intron)
            unpublished

CYP83A1     Arabidopsis thaliana
            GenEMBL AL161537    
            CDS complement(join(82790..83413,83506..84390))

CYP83A2X    Arabidopsis thaliana
            D78598 (500 amino acids) also AL080238
            Mizutani,M., Ward,E. and Ohta,D.
            Cytochrome p450 superfamily in Arabidopsis thaliana: isolation of
            cDNAs, differential expression, and RFLP mapping of multiple
            cytochromes P450
            Plant Mol. Biol. 37, 39-52 (1998)
            P450-2
            ESTs R86798, T76397, T44634, R30228, T88645, N65459
            T46080, T75944, Z33831, Z34720, AA404945, T20600
            This sequence was renamed as CYP83A2 due to an improved sequence
            alignment.  The old name was CYP83B1.  83A1 and 83A2 are greater than 58% 
            identical.  Due to use of 83B1 in at least four publications, the name of this sequence 
            will continue to be CYP83B1 even though it should be 83A2 based on the revised sequence.
            The use of the old less accurate name CYP83B1 is to prevent confusion in the literature.

83B Subfamily

CYP83B1     Arabidopsis thaliana
            GENEMBL D78598 (500 amino acids)
            Mizutani M, Ward E, Ohta D
            Cytochrome P450 superfamily in Arabidopsis thaliana: isolation of
            cDNAs, differential expression, and RFLP mapping of multiple
            cytochromes P450.
            Plant Mol Biol 1998 May;37(1):39-52 
            P450-2
            ESTs R86798, T76397, T44634, R30228, T88645, N65459
            T46080, T75944, Z33831, Z34720, AA404945, T20600
            This sequence was renamed as CYP83A2 due to an improved sequence
            alignment.  However, 83B1 has appeared in at least four publications, 
            so CYP83B1 is preferred for historical reasons.

CYP83B1     Arabidopsis thaliana
            GenEMBL AL161579 
            CDS complement(join(39621..40238,40334..41215))

83C Subfamily

CYP83C1     Petroselinum crispum (parsley)
            no accession number
            Imre Somssich
            submitted to nomenclature committee
            formerly 83B2, but given its own subfamily
            47.3% identical to 83A2

83D Subfamily

CYP83D1     Glycine max (soybean)
            GenEMBL AF022460 (1657bp)
            Siminszky,B., Dewey,R.E. and Corbin,F.T.
            clone name 7/16
            this sequence is a best match to 71A1 45.7% identity, but is a poor match to 
            some 71B sequences (35%).  This makes the tree program cluster it with CYP83,  
            because it is consistently similar to 83 sequences.  The 83 family is the next family 
            after 71 and they sort of run together.  This sequence may belong in the 71 family,  
            but it is hard to tell.  The CYP71 and 83 cluster is one of the most populated and
            difficult clusters to classify on the plant P450 tree.

CYP83D2X    Medicago sativa (alfalfa)
            no accession number
            Chris Steele
            clone B36
            submitted to nomenclature committee
            sequence below released directly from Chris Steele
            This sequence is not in Genbank (1/19/01)
            Renamed CYP83E1 since the sequence is only 48% identical to 83D1

CYP83E1     Medicago sativa (alfalfa)
            no accession number
            Chris Steele
            clone B36
            submitted to nomenclature committee
            sequence below released directly from Chris Steele
            This sequence is not in Genbank (1/19/01)
            Formerly 83D2, renamed CYP83E1 since the sequence is only 48% identical to 83D1

>31 C Steele, July 30, 1997 13:47. B36 83D2 Medicago sativa (alfalfa)

  1 MLPMLLLLVLCLT LPLLMFFHKH KTNTNNPPGP KGLPIIGNLL QLDISNLHLQ
 51    FSQFSKIYGP LFSLQLGLRP AIVVSSAEIA KEVFKNNDHV FSNRPISYGQ
101    NILSYNGSEI VFAPYGDFWR EIRKICAIHI FSSKRVSYYS SIRIFEVKKM
151    IKNISVHADS SNVTNLSELL ISLSSTIICR TAFGKSYEDD GIEKSRFHGL
201    LHEFQALLAA SFFADYIPFT GWIDKLRGLH GRVDRNFKEF DEFYQEIIDE
251    HLDPNREQIT DEEDIVDVLL ELKKKRSFSF DINFDHIKGI LTDMLVAATD
301    TTSAASVWAM TALIKNPRVM SKVKGEIRNL GVKKDFLYED DIQNCPYLKA
351    VVKETLRLHL PAPLLVPRES IENCTINGYN IPAKTILYVN AWAIQRDPDI
401    WINPEEFYPE RFLESSINFI GQDFELIPFG AGRRICPSIP MAVASLELIL
451    ANLLYSFDWK LPHGLVKEDI DTSMLPGITQ HKKNPLCLIA KVPK*

CYP83E2     Lotus japonicus
            No accession number 
            Soren Bak and Susanne Paquette
            Submitted to nomenclature committee 4/10/2003
            71% to 83E1 93% TO 83E3
            clone name CYP83LT2

CYP83E3     Lotus japonicus
            No accession number 
            Soren Bak and Susanne Paquette
            Submitted to nomenclature committee 4/10/2003
            71% to 83E1 83% to 83E5
            clone name CYP83LT4

CYP83E4     Lotus japonicus
            No accession number 
            Soren Bak and Susanne Paquette
            Submitted to nomenclature committee 4/10/2003
            71% to 83E1 82% to 83E5
            clone name CYP83LT5

CYP83E5     Lotus japonicus
            No accession number 
            Soren Bak and Susanne Paquette
            Submitted to nomenclature committee 4/10/2003
            70% to 83E1 51% to 83D1 83% to 83E3
            clone name CYP83LT6

CYP83E6     Lotus japonicus
            No accession number 
            Soren Bak and Susanne Paquette
            Submitted to nomenclature committee 4/10/2003
            55% to 83E1 45% to 83D1 94% TO 83E7
            clone name CYP83LT3

CYP83E7     Lotus japonicus
            No accession number 
            Soren Bak and Susanne Paquette
            Submitted to nomenclature committee 4/10/2003
            54% to 83E1 alfalfa 94% TO 83E6 56% TO 83E4
            clone name CYP83LT

84A Subfamily

CYP84A1       Arabidopsis thaliana
            GenEMBL U38416 (1838bp)
            Meyer, K., Cusumano, J.C., Somerville, C. and Chappel, C.C.
            Ferulate-5-hydroxylase from Arabidopsis thaliana defines a new
            family of cytochrome P450-dependent monoxygenases.
            Proc. Natl. Acad. Sci. USA 93, 6869-6874 (1996)
            clone pCC30

            Meyer, K., Shirley, A.M., Cusumano, J.C., Bell-Lelong, D.A. and 
            Chapple, C.
            Lignin monomer composition is determined by the expression of a cytochrome 
            P450-dependent monooxygenase in Arabidopsis 
            PNAS 95, 6619-6623 (1998)
            functional characterization of CYP84A1

CYP84A1       Arabidopsis thaliana
            GenEMBL AL022141  F23E13.110
            (see note to CYP84A3 about function)

CYP84A2    Solanum lycopersicum(tomato) (also Lycopersicon esculentum)
           GenEMBL AF150881
           G. Paul Bolwell, Jonathan Rees
           Ferulate-5-Hydroxylase (see note to CYP84A3)
           69% identical to 84A1

CYP84A3     Liquidambar styraciflua (sweetgum)
            GenEMBL AF139532
            Osakabe,K., Tsao,C.C., Li,L., Popko,J.L., Umezawa,T.,
            Carraway,D.T., Smeltzer,R.H., Joshi,C.P. and Chiang,V.L.
            Coniferyl aldehyde 5-hydroxylation and methylation direct syringyl
            lignin biosynthesis in angiosperms
            Proc. Natl. Acad. Sci. U.S.A. 96, 8955-8960 (1999)
            75% identical to CYP84A1
            Note: This paper shows coniferyl aldehyde 5-hydroxylation as the primary 
            function of the CYP84A P450s and not ferulate-5-hydroxylation.  When both 
            coniferyl aldehyde and ferulate are present, coniferyl aldehyde is a noncompetitive 
            inhibitor of ferulate-5-hydroxylation and shuts down this potential pathway.

CYP84A4    Arabidopsis thaliana
            GenEMBL AF267140 partial seq
            Rees J.D., Bolwell, G.P.
            59% identical to 84A1

CYP84A     Lycopersicon esculentum (tomato)
           GenEMBL AI772808
           75% identical to 84A1 from amino acids 382-520

CYP84A     Lycopersicon esculentum (tomato)
           GenEMBL AI894552
           78% identical to 84A1 from amino acids 297-418

CYP84A4   Populus trichocarpa cv trichobel 
          GenEMBL AJ010324
          Van Doorsselaere,J., Ardiles-Diaz,W., Van Montagu,M. and Boerjan,W.
          Nucleotide sequence of a cDNA encoding ferulate-5-hydroxylase (f5h)
          from poplar (Populus trichocarpa)
          Unpublished
          mRNA for ferulate-5-hydroxylase f5h gene 
          Populus balsamifera subsp. trichocarpa.
          78% identical to 84A3

CYP84A    Populus balsamifera subsp. trichocarpa
          GenEMBL AI166384 xylem.est.221
          94% identical to 84A3 

CYP84A    Glycyrrhiza echinata (licorice)
          GenEMBL D89434
          Akashi,T., Aoki, T., Takahashi,T., Kameya,N., Nakamura, I. and Ayabe, S.
          Cloning of cytochrome P450 cDNAs from cultured Glycyrrhiza echinata L. cells 
          and their transcriptional activation by elicitor treatment.
          Plant Science 126, 39-47 (1997)
          Ge-6 C-terminal PCR fragment 

CYP84A     Glycyrrhiza echinata (licorice)
           GenEMBL D89435
           Akashi,T., Aoki, T., Takahashi,T., Kameya,N., Nakamura, I. and Ayabe, S.
           Cloning of cytochrome P450 cDNAs from cultured Glycyrrhiza echinata L. cells 
           and their transcriptional activation by elicitor treatment.
           Plant Science 126, 39-47 (1997)
           Ge-7 C-terminal PCR fragment 

CYP84A     Glycine max
           GenEMBL AI495616
           78% identical to 84A1 from amino acids 375-516

CYP84A     Populus tremula x Populus tremuloides
           GenEMBL AI166206 
           81% identical to 84A1 from amino acids 274-368


85A Subfamily

CYP85A1     Solanum lycopersicum(tomato) (also Lycopersicon esculentum)
            GenEMBL U54770 (1395bp)
            Bishop,G.J., Harrison,K. and Jones,J.J.G.D.
            The tomato dwarf gene isolated by heterologous transposon tagging
            encodes the first member of a new family of cytochrome P450
            Plant Cell 8, 959-969 (1996)

CYP85A1     Arabidopsis thaliana (Thale cress)
            GenEMBL AB009048
            ESTs: N65267, T76590, AA394869, AA404883, AA713019, GSS: B09951
            This protein seems short, but the ESTs confirm the intron exon 
            Boundaries.  67% to tomato CYP85A1

CYP85A2     Arabidopsis thaliana (Thale cress)
            GenEMBL AP002060
            82% to Arabidopsis CYP85A1, 68% to tomato CYP85A1
            note: This appears to be a recent duplication in Arabidopsis
            this second 85A gene may not exist in other plants outside the 
            Brassicales.

86A Subfamily

CYP86A1     Arabidopsis thaliana (Thale cress)
            GenEMBL X90458 (1728bp) AB016885
            Benveniste,I. and Durst,F.
            Cloning, sequencing and expression of CYP86, a new cytochrome P450
            from Arabidopsis thaliana
            CYPIRE
            Additional EST fragments: T45669, R90073, Z26357, Z26358 and Z35025

CYP86A2     Arabidopsis thaliana
            GenEMBL AF013293 AF195115
            ESTs T04172 (310bp) H76762 (492bp) C-helix region
            Additional ESTs T46372, T46373, N95869, Z25705

CYP86A3     Brassica campestris (field mustard) EST
            L35832 (310bp)
            90% identical to 86A2, 71% identical to 86A1

CYP86A4     Arabidopsis thaliana (Thale cress)
            GenEMBL Y09581(region of ~11000-12678)(512 amino acids)
            Quentin J. Groom
            submitted to nomenclature committee

CYP86A5    Triticum aestivum (wheat)
           no accession number
           Francis Durst
           submitted to nomenclature committee

CYP86A6    Triticum aestivum (wheat)
           no accession number
           Francis Durst
           submitted to nomenclature committee
           only 8 differences with 86A5

CYP86A7    Arabidopsis thaliana
           GenEMBL AC011622 43171-44742 clone F24D7
           78% identical to 86A2
           EST F14165 

CYP86A8    Arabidopsis thaliana
           GenEMBL AC004665 61000-63000 region
           GenEMBL AC005397 (109407..110149) gene = T3F17.38
           GenEMBL AC005861
           GenEMBL Z17399 genomic sequence of another gene has C-terminal of 86A8 on 
           minus strand at the end
           77% identical to CYP86A2

CYP86B1      Arabidopsis thaliana (Thale cress)
            GenEMBL AB007648 (comp. 14676-16659)
            Complete sequence 

CYP86B2      Arabidopsis thaliana (Thale cress)
            GenEMBL AL357612.1 complement(join(80435..80836,81200..82450))
            Also on overlapping clone F8L15 AL392174.1
            Complete sequence 78% identical to 86B1
            Gene = T22D6_190

CYP86C1      Arabidopsis thaliana (Thale cress)
            GenEMBL AC000103 F21J9.9
            Complete sequence 

CYP86C2    Arabidopsis thaliana
           GenEMBL AB024038 1-1074
           missing N-terminal, but Z26058 matches C-term
           and Z26059 codes for the N-terminal of this same clone 
           so there is only a small piece missing just beyond the C-helix
           GenEMBL AP000601 provides the missing 38 internal 
           amino acids for CYP86C2

CYP86C3    Arabidopsis thaliana
           GenEMBL AC007357 comp(51369-52951)

CYP86C4    Arabidopsis thaliana
           GenEMBL AC007357 comp(54696-56285)

CYP86D1X    Arabidopsis thaliana
           GenEMBL AC023279 comp(55362-56858) 
           March 6, 2000 renamed CYP94D1

CYP86D2PX   Arabidopsis thaliana
           GenEMBL AC024226 comp(6890-7005) 
           numerous deletions and frameshifts
           GSSs AL080732, AQ010792 renamed CYP94D3P

87A Subfamily

CYP87A1     Helianthus annuus (sunflower)
            Andre Steinmetz and Francis Durst
            SF28
            submitted to nomenclature committee 4/11/95

CYP87A1     Helianthus annuus (sunflower)
            Dr. V.Tabidze
            submitted to nomenclature committee 5/20/99

CYP87A1     Helianthus annuus (sunflower)
            GenEMBL AF216313
            Tabidze,V., Durst,F. and Steinmetz,A.A.
            Partial nucleotide sequence of a sunflower cytochrome P450 mRNA

CYP87A2     Arabidopsis thaliana
            GenEMBL AC025417 67020-68647 75% to 87A1 partial seq
            ESTs H77048 and N37614 
            Still missing N-terminal 145 amino acids

CYP87A3P    Arabidopsis thaliana
            GenEMBL AC010926

CYP87       Medicago truncatula
            GenEMBL AA660764 00656 MtRHE
            59% identical to N-terminal of CYP87A1
GLPLLGESLQFFSPNTSCDIPPFIRKRMKRYGPIFKTNLVGRPVVVSTDPDLNYFIFQQE 
GKIFQSWYPDTFTEIFGQQNVXSLHGFMYKYLKNMMLNLFGPESLKKMISEVEQAACXTL 

88A Subfamily

CYP88A1     Zea mays
            GenEMBL U32579 (1724bp)
            Winkler,R.G. and Helentjaris,T.
            The maize dwarf3 gene encodes a cytochrome P450-mediated early step
            in gibberellin biosynthesis
            Plant Cell 7, 1307-1317 (1995)

CYP88A2     Cucurbita maxima (pumpkin)
            GenEMBL AF212991
            Helliwell,C.A., Olive,M.R., Gebbie,L., Forster,R., Peacock,W.J. and
            Dennis,E.S.
            Isolation of an ent-kaurene oxidase cDNA from Cucurbita maxima
            Aust. J. Plant Physiol. 27, 1141-1149 (2000)

CYP88A3     Arabidopsis thaliana (Thale cress)
            GenEMBL AC000098
            YUP8H12.23
            ESTs: T43711

CYP88A4     Arabidopsis thaliana
            GenEMBL AC005700
            gene=T32F6.4
            56% identical to 88A1 no ESTs GSS: AL088126 BAC end T1G2

CYP88A5   Oryza sativa (rice)
GenEMBL   AP000616 Oryza sativa genomic DNA, chromosome 6, clone:P0514G12
              Length = 138739
              
Query: 1      MESTWAVAAVVTAVVAVATVFSVLKWAAKSLNEWIYEAKLG-DRRLALPPGDLGWPLIGN 59
              M + WA   +     AV     ++    +  ++W+  A LG +RR  LPPG++GWP++G+
Sbjct: 125075 MAAAWAAGDLWVLAAAVVAGVVLVDAVVRRAHDWVRVAALGAERRSRLPPGEMGWPMVGS 125254

Query: 60     MLGFLRAFKSKNPETFIDGYVSR 82
              M  FLRAFKS NP+ FI  ++ R
Sbjct: 125255 MWAFLRAFKSGNPDAFIASFIRR 125323

Query: 83     YGKTGVYKVHLFGNPSVVVTTPETCRKVLTDDEAFQPGWPRAAVELIGEKSFIQMPQEE 141
              +G+TGVY+  +F +P+++  TPE C++VL DDE F  GWP+A V LIG KSF+ M  ++
Sbjct: 127995 FGRTGVYRTFMFSSPTILAVTPEACKQVLMDDEGFVTGWPKATVTLIGPKSFVNMSYDD 128171

Query: 142    HKRLRRLTSAPVNGFEALSNYIPYIEKNVLESLEKWS--KMGPIEFLTQLRKLTFTVIMY 199
              H+R+R+LT+AP+NGF+AL+ Y+ +I++ V+ SL +WS  + G +EFLT+LR++TF +I+ 
Sbjct: 128172 HRRIRKLTAAPINGFDALTTYLSFIDQTVVASLRRWSSPESGQVEFLTELRRMTFKIIVQ 128351

Query: 200    IFLSSESEPVMEMLEKEYTRLNYGVRDMRINLPGFAYHKALKARKNLVAALKGIVTERRR 259
              IF+S   +  ME LE+ YT LNYG+R M INLPGFAY++AL+AR+ LV+ L+G++  RR 
Sbjct: 128352 IFMSGADDATMEALERSYTDLNYGMRAMAINLPGFAYYRALRARRKLVSVLQGVLDGRRA 128531

Query: 260    QKLDKWAPK-RKDMMDQLIDIVDENGRKLDDEEIIDILIMYLNAGHESSGHTMMWATILL 318
                   +      DMMD+LI+  DE GR+L D+EI+D+LIMYLNAGHESSGH  MWAT+ L
Sbjct: 128532 AAAKGFKRSGAMDMMDRLIEAEDERGRRLADDEIVDVLIMYLNAGHESSGHITMWATVFL 128711

Query: 319    NQHPEVLKKAREEQEAIVRNRPAG 342
               ++P++  +A+ EQE I+R+ PA 
Sbjct: 128712 QENPDIFARAKAEQEEIMRSIPAT 128891

Query: 343    QTGLTLKECRDMEYLS 358
              Q GLTL++ + M +LS
Sbjct: 128892 QNGLTLRDFKKMHFLS 128939

Query: 359    KVVDETLRYVSFSLVVFREAQMDVNLNG 386
              KVVDETLR V+ S V FR+A  D+ +NG
Sbjct: 129445 KVVDETLRCVNISFVSFRQATRDIFVNG 129528

Query: 387    YLIPKGWKVLAWFRSIHYDSEVYPDPKKFEPSRWD 421
              YLIPKGWKV  W+RS+H D +VYPDPK F PSRW+
Sbjct: 129707 YLIPKGWKVQLWYRSVHMDDQVYPDPKMFNPSRWE 129811

Query: 422    GFVPKAGEFLPFGAGSRLCPGNDLAKLEICIFVHYFLLNY 461
              G  PKAG FLPFG G+RLCPGNDLAKLEI +F+H+FLL Y
Sbjct: 129937 GPPPKAGTFLPFGLGARLCPGNDLAKLEISVFLHHFLLGY 130056

Query: 463    LEWLTPDCEILYLPHSRPKDNCMAKITKKS 492
              L+   P C + YLPH RP DNC+A ITK S
Sbjct: 130322 LKRANPKCRVRYLPHPRPVDNCLATITKVS 130411

81% to 88A1 54% to 88A2
MAAAWAAGDLWVLAAAVVAGVVLVDAVVRRAHDWVRVAALGAERRSRLPPGEMGWPMVGS 125254
MWAFLRAFKSGNPDAFIASFIRR 125323
FGRTGVYRTFMFSSPTILAVTPEACKQVLMDDEGFVTGWPKATVTLIGPKSFVNMSYDD 128171
HRRIRKLTAAPINGFDALTTYLSFIDQTVVASLRRWSSPESGQVEFLTELRRMTFKIIVQ 128351
IFMSGADDATMEALERSYTDLNYGMRAMAINLPGFAYYRALRARRKLVSVLQGVLDGRRA 128531
AAAKGFKRSGAMDMMDRLIEAEDERGRRLADDEIVDVLIMYLNAGHESSGHITMWATVFL 128711
QENPDIFARAKAEQEEIMRSIPAT 128891
QNGLTLRDFKKMHFLS 128939
KVVDETLRCVNISFVSFRQATRDIFVNG 129528
YLIPKGWKVQLWYRSVHMDDQVYPDPKMFNPSRWE 129811
GPPPKAGTFLPFGLGARLCPGNDLAKLEISVFLHHFLLGYX 130056
LKRANPKCRVRYLPHPRPVDNCLATITKVS 130411

CYP88A6 pisum sativum (pea)
        GenEMBL AF537321
        The pea gene NA encodes ent-kaurenoic acid oxidase
        Sandra E. Davidson, Robert C. Elliott, Chris A. Helliwell, Andrew
        Poole, and James B. Reid (2003) Plant Physiology, 131 (1), 335-344.
        Submitted to nomenclature committee August 13, 2002
        Clone name PsKAO1 ent-kaurenoic acid oxidase
        66% to 88A4, 75% to 88A7

CYP88A7 pisum sativum (pea)
        GenEMBL AF537322
        The pea gene NA encodes ent-kaurenoic acid oxidase
        Sandra E. Davidson, Robert C. Elliott, Chris A. Helliwell, Andrew
        Poole, and James B. Reid (2003) Plant Physiology, 131 (1), 335-344.
        Submitted to nomenclature committee August 13, 2002
        Clone name PsKAO2 ent-kaurenoic acid oxidase
        63% to 88A4, 75% to 88A6

CYP88B1     tomato
            GenEMBL ESTs only (lots of ESTs)
            40% to 88A4
MDFYNLALFFIALILGIFTFYAILMRINGWYYAIKFCSNKYNIPN
GYMGLPYFGNTLSYFKASMCGDPKSFIDFFATRFGEGGMYRAYIF
GKPTIMVTKPEIIRKVLMDEEYLERGLPNYMKKLIGLTTSIEEDK
YFRRLTAPVKSHGLLSDYFDYIDKTVSSTLEKYATTEEPVEFLHK
MHKLTFEVFMRLLIGDEVNQELFDEMFEEITAVISGVHNLPINLP
GFAYHKGLKARKVLXEVFKKLIDERREAMKDGKSMPKANIIDMLL
SNNNQDYEANMLSDKKIIEILVLFSFAGFEPVALMSVKAIFHLQK
HPHFLEKAKEEQEEIVKRRASSNAGLSFDEIRQMTFVSKIINETL
RIATDQSVFLRDTST TFNINGYTIPKGWKFFAVVWNIHMNPDVY
VQPKEFNPSRWDDIETKPGIFLPFSMGPKSCPGSNLAKLQISVIL
HYYLLHYRVEQINPEARCYPPENCLVKFKKLSISSNGN*

89A Subfamily

CYP89A1        Vicia sativa
            no accession number
            Francis Durst
            submitted to nomenclature committee

CYP89A2      Arabidopsis thaliana (Thale cress)
            GenEMBL U61231 (1787bp) (PGR-061), AC006193 comp(66014-67477+)
            Courtney, K.J.,   Percival, F.W., Hallahan, D.L. and Christoffersen, R.E.,
            Cloning and sequencing of a cytochrome P450, CYP89, from
            Arabidopsis thaliana .
            Plant Physiol., 1996 in press
            This is probably identical to 89A8 if three frame shifts and a few other 
            sequence differences are due to sequence errors.  The 3 prime and 5 prime  
            untranslated sequences are nearly identical, which is unlikely if they are 
            different genes.

CYP89A3       Arabidopsis thaliana (Thale cress)
            GenEMBL AB010073 comp(25500-27000 region)

CYP89A4      Arabidopsis thaliana (Thale cress)
            GenEMBL AC005897 comp(42064 40565) AC007045 10850-12400
            80% identical to CYP89A2

CYP89A5      Arabidopsis thaliana (Thale cress)
            GenEMBL AC006193 comp(51700-53166+)
            92% identical to CYP89A4
            ESTs H77059

CYP89A6      Arabidopsis thaliana (Thale cress)
            GenEMBL AC006193 comp(55495-56982+)

CYP89A7      Arabidopsis thaliana (Thale cress)
            GenEMBL AC006193 comp(58358-59827+)

CYP89A8X      Arabidopsis thaliana (Thale cress)
            GenEMBL AC006193 comp(66014-67477+)
            This is probably identical to 89A2 if three frame shifts and a few other 
            sequence differences are due to sequence errors.  The 3 prime and 5 prime  
            untranslated sequences are nearly identical, which is unlikely if they are 
            different genes.

CYP89A9       Arabidopsis thaliana
            GenEMBL AC009895 37255-38905 
            clone T21P5 
            54% to 89A4 
            ESTs T76749, T44110, T45663, T14186, T21361, AA394479

CYP89A-like     Mesembryanthemum crystallinum (ice plant)
            GenEMBL AI026356
KYGPIIAIHRDRGPLIMSFDHALAHEALVQKGAIFAGRPKALPARRVISSNQH
TISTAGYGPTWRLLRRNLTSQILHPTRVKEYSHARKWVLNILLTRLRDSA
NEGGDGVVVMVKDHLQFAMFCLLVLMCFGDKLDESTIREIEDVQT

CYP89A-like     Oryza sativa (rice)
          GenEMBL AU062487
          Sasaki,T. and Minobe,Y.
          Rice cDNA from callus
          Unpublished (1994)
          59% identical to 89A2 possible 89A sequence

CFEGLXKHPPGHMLLPHRSAEXMEIGGYLIPKGTTXNFMVAEMGRDEKEW
EKPMEFMPERFXXXXXXXXXXXXQGDPDDPFGVGRXICAGLGVAMLHVE
YFVANMVSEFEWKEVAGDEVDFAEKIEFX

CYP89A-like     Oryza sativa (rice)
            GenEMBL AA754418
            Nahm,B.H., Kim,J.K., Cheong,J.J., Kim,S.I., Hahn,T.R, Moon,E.P.,
            Kim,W.T., Kim,W.Y., Yang,M.S., Park,R.D., Sohn,U.I., Kang,K.Y.,
            Lee,M.C. and Eun,M.Y.
            Large-scale Sequencing Analysis of ESTs from Rice Immature Seed
            Unpublished (1998)
            74% identical to 89A2 C-term
IRHEXXXLTGSKEIKXMPFGAGRRVCPGMALALLHLEYFVANLVWEFDWR
EVAGDEVDLTEKLEFTVVMKRPLKATAVPLRXTRSAAVE*

90A Subfamily

CYP90A1      Arabidopsis thaliana
             GenEMBL X87367 mRNA (1608bp) GenEMBL X87368 gene (4937bp)
             Szekeres,M., Nemeth,K., Koncz-Kalman,Z., Mathur,J., Kauschmann,A.,
             Altmann,T., Redei,G.P., Nagy,F., Schell,J. and Koncz,C.
             Brassinosteroids rescue the deficiency of CYP90, a cytochrome P450,
             controlling cell elongation and de-etiolation in Arabidopsis
             Cell 85 (2), 171-182 (1996)
             same as EST Z17988 and EST Z26124
             additional ESTs T41675, N38445, T43151, T43286, T22324, T22325
             Z29017, Z29018

CYP90A1      Arabidopsis thaliana
             GenEMBL AB005237 comp(27500-23500) region

CYP90A-like      Saccharum sp.(sugar cane)
            GenEMBL AA961302 (626bp)
            Carson,D.L. and Botha,F.C.
            Sugarcane cDNA from mature stalk tissue
            Unpublished (1997)
            73% id to CYP90 C-term
RLCPGYELARVVVSVFLHHLVTRFSWEEAEEDRIVFFPTTRTLKGYPINLRRRPDYDDF*

CYP90A2     Vigna radiata (mung bean)
            GenEMBL AF279252
            Yang,M.T. and Chen,Y.M. 
            Cloning and sequencing of a Vigna radiata cDNA 
            encoding cytochrome P450 
            Unpublished
            mRNA, complete cds; nuclear gene for chloroplast product. CipCYP
            77% identical to 90A1

90B Subfamily

CYP90B1       Arabidopsis thaliana
            GenEMBL AF044216 also AL132979
            Sunghwa Choe, Feldmann Lab
            steroid 22 alpha hydroxylase (DWF4 gene)
            42.2% identical to 90A1

CYP90C1      Arabidopsis thaliana
             GenEMBL Z99708 
             Complete sequence
             ESTs: AA651564, N96214, GSS: AQ011208

CYP90C1      Arabidopsis thaliana
             GenEMBL AL022141 
             F23E13.220 C-terminal sequence
             ESTs: AA651564

CYP90C1      Arabidopsis thaliana
             GenEMBL AB008097
             Kim,G.T., Tsukaya,H. and Uchimiya,H.
             The ROTUNDIFOLIA3 gene of Arabidopsis thaliana encodes a new member
             of the cytochrome P-450 family that is required for the regulated
             polar elongation of leaf cells.
             Genes Dev. 12, 2381-2391 (1998) 

CYP90D1      Arabidopsis thaliana
             GenEMBL AP001307 comp(43183-45689) 
             51% to 90C ESTs = AI994541, R30379, R30380

91A Subfamily


Note: The 81 and 91 families have been joined due to new Arabidpsis sequences that have 
strong sequence identity to both families.  The CYP91 family sequences have been 
renamed with new CYP81 family names.  The old names will still be recognized, but the 
newer names will be preferred.

CYP91A1     Arabidopsis thaliana
            no accession number (500 amino acids)
            Mizutani, M. 
            unpublished (1995)
            P450-65
            New name CYP81D1

CYP91A2     Arabidopsis thaliana
            no accession number (500 amino acids)
            Mizutani, M. 
            unpublished (1995)
            P450-66-8
            new name CYP81F1

CYP91A3     Arabidopsis thaliana
            GenEMBL H76015 (EST)
            73.3% identical with 91A1 (over 105 amino acids)
            new name CYP81D8

CYP91A4     Glycyrrhiza echinata_ L. (licorice; Fabaceae)
            GenEMBL AB001379  or D89431
            Shin-ichi Ayabe
            Ge-3
            50.1% identical to 91A1
            new name CYP81E1

CYP91A5     Cicer arietinum (chickpea)
            no accession number
            Stefan Overkamp and Wolfgang Barz
            submitted to nomenclature committee
            52.7% identical to 91A4
            new name CYP81E2

92A Subfamily

CYP92A1     Zea mays
            GenEMBL AY072297.1
            Persans,M.W., Wang,J. and Schuler,M.A.
            Characterization of maize cytochrome p450 monooxygenases induced in
            response to safeners and bacterial pathogens.
            Plant Physiol. 125 (2), 1126-1138 (2001)
            unpublished in 1995 revised sequence Dec 1 1999 
            old clone name PCR3

CYP92A2    Nicotiana tabacum (tobacco)
           GenEMBL X95342 (1628bp)
           Characterization of hsr201 and hsr215, two tobacco genes 
           preferentially expressed during the hypersensitive reaction 
           provoked by phytopathogenic bacteria.
           Czernic,P., Huang,H.C. and Marco,Y.
           unpublished (1996)

CYP92A3    Nicotiana tabacum (tobacco)
           GenEMBL X96784 (3702bp)
           Czernic,P. and Marco,Y.
           unpublished (1996)

CYP92A4    Zea mays (maize)
           no accession number 
           Mike Barrett
           clone B
           submitted to nomenclature committee
           95% identical to revised 92A1 Dec. 1, 1999

CYP92A5     Nicotiana tabacum (tobacco)
            GenEMBL AF368380
            Ralston L, Kwon ST, Schoenbeck M, Ralston J, Schenk DJ, Coates RM, 
            Chappell J.
            Cloning, heterologous expression, and functional characterization of
            5-epi-aristolochene-1,3-dihydroxylase from tobacco 
            (Nicotiana tabacum).
            Arch Biochem Biophys. 2001 Sep 15;393(2):222-35.
            Submitted to nomenclature committee Nov. 7, 2000
            94% to 92A2

CYP92A6     Pisum sativum (pea)
            GenEMBL AF218296
            Kang,J.-G., Yun,J., Kim,D.-H., Chung,K.-S., Fujioka,S., Kim,J.-I.,
            Dae,H.-W., Yoshida,S., Takatsuto,S., Song,P.-S. and Park,C.-M.
            Light and Brassinosteroid Signals Are Integrated via a Dark-Induced
            Small G Protein in Etiolated Seedling Growth
            Cell 105 (5), 625-636 (2001)
            70% to 92A2
MALQVLTLPSWVTLFTTFAILLLFSRRLRRRQYNLPPGPKPWPIIGNFNL
IGTLPHQSLHGLTQKYGPIMHLWFGSKRVVVGSTVEMAKAFLKTHDATLA
GRPKFSAGKYTTYNYSDITWSQYGPYWRQARRMCLLELFSAKRLESYEYI
RKQELHVFLHELFDSRNKTILLKDHLSSLSLNVISRMVLGRKYLEKVENS
IISPDEFKNMLDELFLLNGILNIGDFIPWIHFLDFQGYVKRMKVLSKKFD
GFMEHVLEEHIERRKGVKDYVAKDMVDVLLQLAEDPDLEVKLERHGVKAF
TQDLIAGGTESSAVTVEWAISELIRKPEIFKKATEELDRVIGRERWVEEK
DIANLPYVYAIAKETMRLHPVAPMLVPREAREDCNINGYDIPKGSLILVN
TWTIARDSNVWDNPNEFMPERFLGKDIDVKGHDYELLPFGAGRRMCPGYP
LGIKVIQSSLANLLHGFNWRLSDDVKKEDLNMEEIFGLSTPKKIH

92B Subfamily

CYP92B1     petunia
            no accession number 
            Hiromasa Imaishi
            submitted to nomenclature committee
            49.1% identical to CYP92A2

93A Subfamily

CYP93A1     Glycine max (soybean)
           GenEMBL D83968 (1653bp)
           Suzuki,G., Ohta, H., Kato,T., Igarashi,T., Sakai,F., Shibata, D., Takano,A.,
           Masuda,T., Shioi, Y. and Takamiya, K.-i.
           Induction of a novel cytochrome P450 (CYP93 family) by methyl jasmonate
           in soybean suspension-cultured cells.
           FEBS Lett. 383, 83-86 (1996)

CYP93A2     Glycine max (soybean)
           GenEMBL D86351 (1829bp)
           Suzuki, G., Ohta, H., Kato, T., Shibata, D., Masuda, T. and Takamiya, K.
           cDNA cloning encoding cytochrome P450 (CYP93A2) from soybean suspension-
           cultured cells.
           unpublished

CYP93A3     Glycine max (soybean)
            GenEMBL Y01492 (1659bp)
            Schopfer,C.R. and Ebel,J.
            Identification of elicitor-induced cytochrome P450s of soybean
            (Glycine max L.) using differential display of mRNA
            Mol. Gen. Genet. 258, 315-322 (1998)
            CP5

CYP93A     Glycyrrhiza echinata (licorice)
            GenEMBL D89432
            Akashi,T., Aoki, T., Takahashi,T., Kameya,N., Nakamura, I. and Ayabe, S.
            Cloning of cytochrome P450 cDNAs from cultured Glycyrrhiza echinata L. cells 
            and their transcriptional activation by elicitor treatment.
            Plant Science 126, 39-47 (1997)
            Ge-4 C-terminal PCR fragment 76.5% identical to 93A2

93B Subfamily

CYP93B1     Glycyrrhiza echinata_ L. (licorice; Fabaceae)
            GenEMBL AB001380 or D89433
            Akashi,T., Aoki,T., Kameya,N., Nakamura,I. and Ayabe,S.
            Two new cytochrome P450 cDNAs (Accession Nos. AB001379 and
            AB001380) from elicitor-induced licorice (Glycyrrhiza echinata L.)
            cells (PGR97-167)
            Plant Physiol. 115, 1288 (1997)
            Akashi,T., Aoki,T. and Ayabe,S.
            Identification of a cytochrome P450 cDNA encoding (2S)-flavanone
            2-hydroxylase of licorice (Glycyrrhiza echinata L.; Fabaceae)
            which represents licodione synthase and flavone synthase II.
            FEBS Lett. 431, 287-290 (1998)
            Ge-5  47.2% identical to 93A1

CYP93B1v2      Glycyrrhiza echinata
            GenEMBL   AB022733
            Akashi,T., Aoki,T. and Ayabe,S.
            A cytochrome P450 cDNA from cultured Glycyrrhiza echinata L. cells
            unpublished (1999) In press
            CYP Ge-51 99% identical to CYP93B1
MEPQLVAVSVLVSALICYFFFRPYFHRYGKNLPPSPFFRLPIIG
HMHMLGPLLHQSFHNLSHRYGPLFSLNFGSVLCVVASTPHFAKQLLQTNELAFNCRIE
STAVKKLTYESSLAFAPYGDYWRFIKKLSMNELLGSRSINNFQHLRAQETHQLLRLLS
NRARAFEAVNITEELLKLTNNVISIMMVGEAEEARDVVRDVTEIFGEFNVSDFIWLFK
KMDLQGFGKRIEDLFQRFDTLVERIISKREQTRKDRRRNGKKGEQESGDGIRDFLDIL
LDCTEDENSEIKIQRVHIKALIMDFFTAGTDTTAISTEWALVELVKKPSVLQKVREEI
DNVVGKDRLVEESDCPNLPYLQAILKETFRLHPPVPMVTRRCVAECTVENYVIPEDSL
LFVNVWSIGRNPKFWDNPLEFCPERFLKLEGDSSGVVDVRGSHFQLLPFGSGRRMCPG
VSLAMQEVPALLGAIIQCFDFQVVGPKGEILKGDDIVINVDERPGLTAPRAHNLVCVP
VERRSGGGPLKIIEC

CYP93B2      (Gerbera hybrid) Barberton Daisy
             GenEMBL AF156976
             Stefan Martens and Forkmann,G.
             submitted to nomenclature committee
             58% identical to 93B1
             flavone synthase II

CYP93B3      Antirrhinum majus (snapdragon)
            GenEMBL AB028151
            T. Akashi, M. Fukuchi-Mizutani, T. Aoki, Y. Ueyama, K.
            Yonekura-Sakakibara, Y. Tanaka, T. Kusumi and S. Ayabe 
            Molecular cloning and Plant and Cell Physiology 
            biochemical characterization of a novel cytochrome P450, flavone synthase II, that           
            catalyzes direct conversion of flavanones to flavones. (1999) in press
            submitted to nomenclature committee 9/4/99
            clone name AFNS2
            60% identical to 93B2
            flavone synthase II

CYP93B4     Torenia (torenia hybrid)
            GenEMBL AB028152
            T. Akashi, M. Fukuchi-Mizutani, T. Aoki, Y. Ueyama, K.
            Yonekura-Sakakibara, Y. Tanaka, T. Kusumi and S. Ayabe 
            Molecular cloning and Plant and Cell Physiology 
            biochemical characterization of a novel cytochrome P450, flavone synthase II, that           
            catalyzes direct conversion of flavanones to flavones. (1999) in press
            submitted to nomenclature committee 9/4/99
            clone name TFNS5
            61% identical to 93B2
            flavone synthase II

CYP93B5      Callistephus chinensis (China aster)
             GenEMBL AF188612
             Stefan Martens and Forkmann,G.
             submitted to nomenclature committee 9/21/99
             76% identical to 93B2
             flavone synthase II

CYP93B6      Perilla frutescens var. crispa (Lamiaceae) (an Asiatic mint that produces oil seeds, Red Perilla, 
             beefsteak plant, chinese basil, purple mint)
             GenEMBL AB045592
             C. Kitada, M. Yamazaki, Y. Tanaka and K. Saito
             76% to 93B4
             flavone synthase II
             clone name PFSII3

93C Subfamily note most 93C sequences appear to be isoflavone synthases.  
Most are 96-99% identical to each other

CYP93C1v1   Glycine max (soybean)
            GenEMBL AF022462 (1824bp)
            Siminszky,B., Dewey,R.E. and Corbin,F.T.
            clone name 9/3

CYP93C1v1   Glycine max (soybean)
            GenEMBL AF195799
            isoflavone synthase 

CYP93C1v1   Glycine max (soybean)
            GenEMBL AF195819
            isoflavone synthase 

CYP93C1v2  Glycine max (soybean)
           GenEMBL AF135484
           Steele,C.L., Gijzen,M., Qutob,D. and Dixon,R.A.
           Molecular Characterization of the Enzyme Catalyzing the 
           aryl Migration Reaction of       
           Isoflavoniod Biosynthesis in Soybean 
           submitted to nomenclature committee 3/12/99
           clone name 41-b

CYP93C2     Glycyrrhiza echinata (licorice)
            GenEMBL D89436 partial sequence 
            Akashi,T., Aoki, T., Takahashi,T., Kameya,N., Nakamura, I. and Ayabe, S.
            Cloning of cytochrome P450 cDNAs from cultured Glycyrrhiza echinata L. cells 
            and their transcriptional activation by elicitor treatment.
            Plant Science 126, 39-47 (1997)
            Ge-8 complete sequence 82% identical to 93C1

CYP93C2     Glycyrrhiza echinata (licorice)
            GenEMBL AB023636 complete sequence
            Akashi,T., Aoki,T. and Ayabe,S.
            Cloning and functional expression of a cytochrome P450 cDNA
            encoding 2-hydroxyisoflavanone synthase involved in biosynthesis of
            the isoflavonoid skeleton in licorice (Glycyrrhiza echinata L.; Fabaceae)
            Unpublished (1999)

CYP93C3     Cicer arietinum (chickpea)
            GenEMBL AJ243804
            Stefan Overkamp and Wolfgang Barz
            submitted to nomenclature committee 12/15/98 revised 7/14/99
            82% identical to 93C1

CYP93C4         Glycine max (soybean)
            GenEMBL AF089850
            Wu,T. and Verma,D.P.S.
            A novel cytochrome P450 cDNA encodes a peroxisomal H2O2-dependent
            urate-degrading peroxidase in soybean
            Unpublished
            94% identical to 93C1v2
MLLELALGLCVLAWFLHLRPTPSAKSKALRHLPNPPSPKPRPPF
IGHLHLLKDKLLHYALIDLSKKHGPLFSLSFGTMATVGGSTPELFKLFLQTHEGTSFN
TRFQTSAIRRLTYDNSVAMVPFGPYWKFVRKLIMNDLLNATTDNKLRPLRTQQIRKFL
RVMAQSAEAQKPLDVTEELLKWTNSTISMMMLGEAEMIRDIAREVLKIFGEYSLTDFI
WPLKYLKVGKYEKRIDDILNKFDPVVERVIKKRREIVRRRKNGEVVEGEASGVFLDTL
LEFAEDETMEIKITKEQIKGLVVDFFSAGTDSTAVATEWALAELVRRSTAVVGKDRLV
DEVDTQNLPYIRAIVKETFRMHPPLPVVKRKCTEECEINGYVIPEGALVLFNVWQVGR
DPKYWDRPSEFRPERFLETGAEGEAGPLDLRGQHFQLLPFGSGRRMCPGVNLATSGMA
TLLASLIQCFDLQVLGPQGQILKGDDPKVSMEERAGLTVPRAHSLVCVPLARIGVASK
LLS

CYP93C5     Glycine max (soybean)
            GenEMBL AF195812, AF195818
            isoflavone synthase 
            99% to 93C14

CYP93C6v1   Vigna radiata 
            GenEMBL AF195806
            isoflavone synthase 
            99% to other 93C6 members

CYP93C6v2   Vigna radiata 
            GenEMBL AF195807
            isoflavone synthase 
            99% to other 93C6 members

CYP93C6v3   Vigna radiata 
            GenEMBL AF195808
            isoflavone synthase 
            99% to other 93C6 members

CYP93C6v4   Vigna radiata 
            GenEMBL AF195809
            isoflavone synthase 
            99% to other 93C6 members

CYP93C7v1   Medicago sativa (alfalfa)
            GenEMBL AF195801
            isoflavone synthase 
            99% to 93C9v2

CYP93C7v2   Medicago sativa (alfalfa)
            GenEMBL AF195802
            isoflavone synthase 
            99% to 93C9v2

CYP93C8     Medicago sativa (alfalfa)
            GenEMBL AF195800
            isoflavone synthase 
            99% to 93C5

CYP93C9v1   Trifolium pratense
            GenEMBL AF195810
            isoflavone synthase 
            99% to 93C9v2

CYP93C9v2   Trifolium pratense
            GenEMBL AF195811
            isoflavone synthase 
            99% to 93C9v1

CYP93C10v1  Trifolium repens
            GenEMBL AF195814
            isoflavone synthase 
            99% to 93C5

CYP93C10v2  Trifolium repens
            GenEMBL AF195815
            isoflavone synthase 
            99% to 93C5

CYP93C11v1  Beta vulgaris
            GenEMBL AF195816
            isoflavone synthase 
            98% to 93C6v2

CYP93C11v2  Beta vulgaris
            GenEMBL AF195817
            isoflavone synthase 
            99% to 93C6v2

CYP93C12    Lens culinaris
            GenEMBL AF195805
            isoflavone synthase 
            99% to 93C6v2

CYP93C13    Lens culinaris
            GenEMBL AF195804
            isoflavone synthase 
            98% to 93C5

CYP93C14    Pisum sativum (pea)
            GenEMBL AF195812
            isoflavone synthase 
            99% to 93C5

CYP93C15    Vicia villosa
            GenEMBL AF195803
            isoflavone synthase 
            99% to 93C9v2

CYP93C16    Lupinus albus (lupine)
            GenEMBL AF195813
            isoflavone synthase 
            98% to 93C6v2

CYP93C17    Lotus japonicus (lotus)
            GenEMBL AB024931
            85% to 93C3

CYP93C18    Pisum sativum (pea)
            No accession number
            Lol Cooper
            Submitted to nomenclature committee May 30, 2002
            80% to 93C14

93D Subfamily

CYP93D1 Arabidopsis thaliana (thale cress)
           GenEMBL AB010697 comp(16802-15190)
           no EST matches
           note July 16, 1999: This sequence lies adjacent to CYP712A2 on clone MOJ9
           The names of these two sequences were accidentally swapped
           This has now been corrected.  93D1 starts with MVDLQY
           CYP712A2 starts with MFTLNLDMNYTS

CYP93E1      Glycine max (soybean)
           GenEMBL AF135485
           Steele,C.L., Gijzen,M., Qutob,D. and Dixon,R.A.
           Molecular Characterization of the Enzyme Catalyzing the aryl Migration Reaction of       
           Isoflavoniod Biosynthesis in Soybean 
           submitted to nomenclature committee 3/12/99
           clone name 1138

94A Subfamily

CYP94A1     Vicia sativa
            GenEMBL AF030260
            Tijet,N., Helvig,C., Pinot,F., Le Bouquin,R., Lesot,A., Durst,F.,
            Salaun,J.-P. and Benveniste,I.
            Functional expression in yeast and characterization of a
            clofibrate-inducible plant cytochrome P-450 (CYP94A1) involved in
            cutin monomers synthesis
            Biochem. J. 332, 583-589 (1998
            VAGH111

CYP94A2     Vicia sativa
            GenEMBL AF092917
            Le Bouquin,R., Pinot,F., Benveniste,I., Salaun,J.P. and Durst,F.
            Cloning and functional characterization of CYP94A2, a medium chain
            fatty acid hydroxylase from Vicia sativa
            Biochem. Biophys. Res. Commun. 261 (1), 156-162 (1999)            
            VAGH811

CYP94A3     Vicia sativa
            no accession number
            Francis Durst
            VAGH22 (very similar to 94A2, but different gene)

CYP94A4     Nicotiana tabacum (tobacco)
           no accession number
           Francis Durst
           submitted to nomenclature committee
           sequence t1

CYP94A5     Nicotiana tabacum (tobacco)
           no accession number
           Francis Durst
           submitted to nomenclature committee
           sequence t2

CYP94A6    Nicotiana tabacum (tobacco)
           no accession number
           Francis Durst
           submitted to nomenclature committee
           sequence t3

CYP94A7    Nicotiana tabacum (tobacco)
           no accession number
           Francis Durst
           submitted to nomenclature committee June 18, 1999

CYP94A8    Nicotiana tabacum (tobacco)
           no accession number
           Francis Durst
           submitted to nomenclature committee June 18, 1999

CYP94          Pisum sativum (pea)
               GenEMBL U29335 (277bp)
               Frank,M.R., Deyneka,J.M. and Schuler,M.A.
               Cloning of wound-induced cytochrome P450 monooxygenases expressed
               in pea.
               Plant Physiol. 110, 1035-1046 (1996)
               heme binding region fragment

CYP94B1       Arabidopsis thaliana
            GenEMBL AB007649 (comp. 20641-22173) 
            Complete sequence 

CYP94B2     Arabidopsis thaliana
            GenEMBL AB010797 31152-32636 clone F28J7
            GenEMBL AC011624 15623-16993 clone T18B3
            GenEMBL AC011664 95514-97001 clone F5A18
            55% identical to 94B1

CYP94B3     Arabidopsis thaliana
            GenEMBL AL133315
            Clone T08P19 comp(10683-12101) from the EU Chr 3 project

CYP94C1     Arabidopsis thaliana
            GenEMBL AC005824
            45% identical to 94A1 and 94B1

CYP94D1    Arabidopsis thaliana
           GenEMBL AC023279 comp(55362-56858) 
           March 6, 2000 formerly CYP86D1

CYP94D2    Arabidopsis thaliana
           GenEMBL AL163972 89747-91303 
           chromosome 3 clone T5P19 88% to 94D1

CYP94D3P   Arabidopsis thaliana
           GenEMBL AC024226 comp(6890-7005) 
           numerous deletions and frameshifts
           GSSs AL080732, AQ010792 formerly CYP86D2P

95A Subfamily


Note concerning the CYP95 family. The original CYP95 sequence was based on a PCR fragment.  With the submission of the identical gene from another lab, it is clear that the original PCR fragment had a frame shift in the I-helix region that caused it to be placed
in a separate family CYP95.  The correct sequence is actually the Zea mays homolog of CYP72A, and not in a new family.  The CYP95 family is discontinued.

CYP95A1X      Zea mays
           no accession number (318 amino acids)
           Mike Persans and Mary Schuler
           submitted to nomenclature committee
           PCR4
           Reassigned to CYP72A5

CYP95X       Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69789 (375bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 1 from Fig. 2. renamed as CYP72 fragment

CYP95X       Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69790 (327bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 2 from Fig. 2. renamed as CYP72 fragment.

96A Subfamily

CYP96A1      Arabidopsis thaliana (Thale Cress)
           no accession number 
           Francis Durst
           called ATAG72
           submitted to nomenclature committee

CYP96A1     Arabidopsis thaliana (Thale Cress)
           GenEMBL AC002391 T20D16.19

CYP96A2     Arabidopsis thaliana (Thale Cress)
           GenEMBL AL021811 (F10M6.190)
           63% identical to 96A1

CYP96A2      Arabidopsis thaliana (Thale Cress)
           GenEMBL AL021636 (F10N7.20)

CYP96A3       Arabidopsis thaliana (Thale Cress)
           GenEMBL AC004512

CYP96A4      Arabidopsis thaliana (Thale Cress)
           GenEMBL AB019226 comp(17000-18000 region)
           78% identical to 96A3

CYP96A5    Arabidopsis
            GenEMBL AC007019 F7D8.23
            62% identical to 96A1

CYP96A6P    Arabidopsis thaliana
            GenEMBL AB025623 

CYP96A7      Arabidopsis thaliana
            GenEMBL AC007519 48335-49896
            no ESTs no GSSs

CYP96A8      Arabidopsis thaliana
            GenEMBL AC007519 56507-58060
            no ESTs no GSSs

CYP96A9      Arabidopsis thaliana
            GenEMBL AL078620 54378-55928 
            F23K16.110

CYP96A10      Arabidopsis thaliana
            GenEMBL AL078620 57169-58608 
            F23K16.120

CYP96A11      Arabidopsis thaliana
            GenEMBL AL078620 comp(58770-60179) 
            F23K16.130

CYP96A12      Arabidopsis thaliana
            GenEMBL AL078620 comp(60765-62291) 
            F23K16.140

CYP96A13     Arabidopsis thaliana
            GenEMBL AL162973 69536-71045 
      70% to 96A12 my translation does not agree
      With the translation of the Genbank entry.  
      Small intron vs frameshift?

CYP96A14P     Arabidopsis thaliana 
            GenEMBL AC026480 9579-10061 
            Pseudogene fragment chr I clone F15E12
            GSSs: B20346, B22314

96B Subfamily

CYP96B1    oats
           no accession number
           Baltrusch, M. and Martin Fulda
           submitted to nomenclature committee
           47.2% identical to 96A1 (partial sequence)

CYP96C1       Catharanthus roseus (Madagascar periwinkle)
            GenEMBL AJ238402
            Oudin,A., Clastre,M., Hamdi,S., Rideau,M. and Chenieux,J.C.
            cDNA cloning and expression of CYP96C1 gene, the first member of a
            new subfamily of cytochrome P450. Its correlation with the
            terpenoid indole alkaloid pathway in Catharanthus roseus cells.
            Unpublished
            39% identical to 96A2

97A Subfamily

CYP97A1    Cicer arietinum (chickpea)
           no accession number
           W. Barz
           frameshifted at C-terminal
           submitted to nomenclature committee

CYP97A2X see CYP97C1

CYP97A3    Arabidopsis thaliana
           GenEMBL AC079041 Clone F56M6
           ESTs AA995768 C-terminal, AV560628
           82% to 97A1
           note: this sequence was named CYP97D1 before I discovered 
           it is 82% identical to a confidential sequence 97A1.

97B Subfamily

CYP97B1      Pisum sativum (Pea)
           GenEMBL Z49263(1926bp)
           Baltrusch, M.
           Isolation of cytochrome P450 cDNA from Pisum sativum seedlings.
           unpublished (1996)
           54.5% identical to 97A1  formerly called CYP97A2

CYP97B2      Glycine max (soybean)
            GenEMBL AF022457 (1831bp)
            Siminszky,B., Dewey,R.E. and Corbin,F.T.
            clone name 7/6
            80.8% identical to 97B1
            C terminal is incorrect due to a frameshift correct sequence given below.
Note: Francis Durst alerted me to an error concerning this sequence.  When I originally revised 
the sequence and posted it here, I made a mistkae and put the new C-terminal sequence onto the 97B1 
sequence, so the sequence shown was 97B1 with a short C-terminal 97B2 sequence added.  The 
sequence below is the corrected 97B2 sequence with the last 12 amino acids in a different frame 
than the genbank entry.  Dec. 30, 1999

MSVDTSSTLSTVTDANLHSRFHSRLVPFTHHFSLSQPKRISSIRCQSINTDKKKSSRNLL
GNASNLLTDLLSGGSIGSMPIAEGAVSDLLGRPLFFSLYDWFLEHGAVYKLAFGPKAFVV
VSDPIVARHILRENAFSYDKGVLADILEPIMGKGLIPADLDTWKQRRRVIAPAFHNSYLE
AMVKIFTTCSERTILKFNKLLEGEGYDGPDSIELDLEAEFSSLALDIIGLGVFNYDFGSV
TKESPVIKAVYGTLFEAEHRSTFYIPYWKIPLARWIVPRQRKFQDDLKVINTCLDGLIRN
AKESRQETDVEKLQQRDYLNLKDASLLRFLVDMRGADVDDRQLRDDLMTMLIAGHETTAA
VLTWAVFLLAQNPSKMKKAQAEVDLVLGTGRPTFESLKELQYIRLIVVEALRLYPQPPLL
IRRSLKSDVLPGGHKGEKDGYAIPAGTDVFISVYNLHRSPYFWDRPDDFEPERFLVQNKN
EEIEGWAGLDPSRSPGALYPNEVISDFAFLPFGGGPRKCVGDQFALMESTVALTMLLQNF
DVELKGTPESVELVTGATIHTKNGLWCNLRKRSSLH*

CYP97B3      Arabidopsis thaliana
           GenEMBL Z97337
           CDS       complement(join(194991..195209,195332..195481,
           195572..195633,195780..195871,195957..196045,
           196132..196218,196303..196362,196451..196498,
           196566..196739,196821..197062,197154..197238,
           197305..197412,197492..197663,197908..198050))
           75% identical to 97B1 over 508 amino acids
           C-terminal EST AA040985

CYP97C1    Arabidopsis thaliana
           GenEMBL AL132958
           Kathrin Schrick
           submitted to nomenclature committee 10/15/97
           formerly 97A2 no ESTs no GSSs

CYP97C      Glycine max (soybean)
            GenEMBL AI736606
            91% identical to 97C1 N-terminal

CYP97C      Gossypium hirsutum (cotton)
            GenEMBL AI731695
            76% to 97C1

CYP97D1X    discontinued, renamed CYP97A3

CYP97E1     Skeletonema costatum (marine diatom)
            No accession number
            Shao Yang
            52% to 97B3, 51% to 97B2, 50% to 97B1
            submitted to nomenclature committee Jan 28, 2001
            this is the first full length sequence from a diatom 

CYP97 like     Chlamydomonas reinhardtii C9 (green algae)
           GenEMBL AV390436 
           Asamizu,E., Nakamura,Y., Sato,S., Fukuzawa,H. and Tabata,S.
           A Large Scale Structural Analysis of cDNAs in a Unicellular Green
           Alga, Chlamydomonas reinhardtii. I. Generation of 3433
           Non-redundant Expressed Sequence Tags
           DNA Res. 6, 369-373 (1999)
           58% to 97B2
CLGESLRMYPQPPILIRRALAEDTLPAGLRGDPAGYPIGKGADLFISVWNLHRSPYLWKDPDTFRPERFFEPNSNPDFGGKWAGYRPDAVTGGAALYPNEVASDFAFIPFGGGARKCVGDQFAMFEATVAAAMLLRRFTFRLAVPAEKVGMATGATIHTANGLSMRVTRRTPGGGSGSGAP

CYP97 like    Skeletonema costatum (CCMP 1332) (a marine diatom, 1st Stramenopile P450)
           No accession number
           Shao Yang 
           C-terminal fragment 58% to 97B1, 57% to Chlamydomonas fragment
           Submitted to nomenclature committee 6/30/00

98A Subfamily

CYP98A1     Sorghum bicolor
            GenEMBL AF029856
            Soren Bak, Rachel Alice Kahn, Hanne Linde Nielsen, Birger
            Lindberg Moller, Barbara Ann Halkier
            Cloning of three A-type cytochromes P450, CYP71E1,
            CYP98, and CYP99 from Sorghum bicolor (L.) Moench by
            a PCR approach and identification by expression in
            Escherichia coli of CYP71E1 as a multifunctional
            cytochrome P450 in the biosynthesis of the cyanogenic
            glucoside dhurrin.
            Plant Molecular Biology 36 (3):393-405, 1998.

CYP98A2     Glycine max (soybean)
            GenEMBL AF022458 (1704bp)
            Siminszky,B., Dewey,R.E. and Corbin,F.T.
            clone name 7/18
            69.7% identical to 98A1

CYP98A3     Arabidopsis thaliana (Thale cress)
            GenEMBL AC002409 
            ESTs: T43253, Z35213, N37715, Z35017, AA728684
            Contig 1538 of the TIGR Landsberg erecta sequences has 100% match

CYP98A4    Oryza sativa (rice)
           GenEMBL C74921 (EST) D47937 (EST)
           93% identical to 98A1

CYP98A5    Phaseolus vulgaris L. cv. Contender (kidney bean)
           no accession number
           Adriaan Basson
           Dept. of Biochemistry at the Rand Afrikaans Univ., Johannesburg, South 
           Africa
           submitted to Nomenclature Committee 10/30/98
           84% to 98A2

CYP98A6     Lithospermum erythrorhizon (a Japanese medicinal plant)
            GenEMBL AB017418
            Asteridae; Solananae; Solanales; Boraginaceae; Lithospermum.
            Mizukami,H., Matsuno,M. and Ellis,B.
            cDNA cloning of yeast extract-induced genes in Lithospermum
            erythrorhizon cell suspension cultures by simplified differential
            display
            Unpublished (1999)
            Intact sequence Submitted to nomenclature committee Oct. 25, 2000
            69% identical to 98A2
WIWADYGPHYVKVRKLCNVELFSPKRLEAIRPMREDEYTALVESIYKDCT
KPELKGKSLLVREYLSSVAFNNITRLAFGKRFMDSNGVVNEQGQEFKKIT
HDGIKITAKLSIAEYIPWIRWMFKVEQDALDKFAADRDHLTRVIMEEHIK
SGNTKQHFVDALLTLQKQYDISEDTIIGLLWDMIAAGMDTATISTEWAMA
ELVRNPRVQRKAQEELDRVVGPDRIMTEADVPKSI

CYP98A7        Zea mays
          GenEMBL AI881302 and AI734373
KIGASLSIAQHIPWLRWLAPDDEQAFKAHGERRDRLTVKIMEEHARALKQRGA 
QQHFVDALFTLRDKYDLSDDTVIGLLWDMITAGTDTTVISVEWA 
MAELLRNPRVQEKLQEELDRVVGRDRVLSETDFPNLPYLQAVVKESLRLHPPTPLMLPHR 
ASASVKIAGYDIPKGANVVVNVWAVARDPKVWDSPLEFRPERFLRENIDIKGADFRVLPFGAGRR 
VCPGAQLGINLVASMIGHMLHHFTWTLPSGTCPEDVSMMESPGLVTFMATPLQAVATPRL 

CYP98A8   Arabidopsis thaliana
          GenEMBL AC011765 comp(67700-69163) 
          no ESTs no GSSs


CYP98A9   Arabidopsis thaliana
          GenEMBL AC011765 comp(70394-71887) 
          GSS AL080882 EST AA651146

CYP98A10   Triticum aestivum (wheat)
           No accession number 
           Daniele Werck-Reichhart
           Clone name 98c
           Submitted to nomenclature committee 3/29/2000
           89% to 98A1

CYP98A11   Triticum aestivum (wheat)
           No accession number 
           Daniele Werck-Reichhart
           Clone name 98f
           Submitted to nomenclature committee 3/29/2000
           89% to 98A1 98% to 98A10

CYP98A12   Triticum aestivum (wheat)
           No accession number 
           Daniele Werck-Reichhart
           Clone name 98-13
           Submitted to nomenclature committee 6/4/2001
           78% to 98A11 66% to 98A3

CYP98A13v1 Ocimum basilicum (basil)
           No accession number
           David Gang
           Submitted to nomenclature committee May 18, 2001
           82% to 98A2
           Clone 1

CYP98A13v2 Ocimum basilicum (basil)
           No accession number
           David Gang
           Submitted to nomenclature committee May 18, 2001
           98% to 98A13v1
           Clone 2

CYP98A14   Coleus blumei
           No accession number
           Maike Petersen
           Submitted to nomenclature committee Jan. 7, 2002
           74% to 98A3

CYP98A15P  rice 
           aaaa01021379.1 CYP98A15P (indica cultivar-group) 
           ortholog AC093612.17b $P chr 10 97%
2574 GEEGKPMVMRKHLSMVAFNNITRLTFGKRFIDAAGELDEQGSELKAIVNNGIKIGASLTI 2395
2394 AEHIRVLRWLNPVDEELYNAHSARRDRFTRRIMDEHARELERHGAKQHFVDALFTLRDKY 2215
2214 DLSDDTVIGLLWDMITAGTDTTVITVEWAMAELARNPRVQMKAQEELDRVIGRGRVMLEA 2035
2034 DIPNLPYLQAVVKESFRLHPPTPLMLPHKASTSVKIAGYDVPKDASVVVNVWAVARDPGV 1855
1854 WDNPLEYRPERFLEESIDIKGSDYRVLPFGAGRRVCPGAQLGISLVASMIGHLLHQFTWA 1675
1674 LPDGTRPEDLDMMESPGLVTFMATPLQVVAMPRLDKEELFKRVPVDM 1534
 
AC093612.17b $P CYP98A15P chromosome 10 clone OSJNBa0003P07, 
Cterminal seq from aa 166 like 98A3
probable pseudogene, no Nterm on this contig between end of 
one in frame stop codon and no introns
83358 GEEGKPMVMRKHLSMVAFNNITRLTFGKRFIDAAGELDEQGSELKAIVNNGIKIGASLTI 83537
83538 AEHIRVLRWLNPVDEELYNAHSARRDRFTRRIMDEHARELERHGAKQHFVDAL 83696
83697 FTLRDKYDLSDDTVIGLLCDMIAAGTDTTVITVEWAMAELVRNPRVQMK 83843
83844 AQEELDRVIGRGRVMLEADIPNLPYLQAVVKESFRLHPPTPLMLPHKASTSVKIAGYD 84017
84018 VPKDASVVVNVWAVARDPGVWDNPLE*RPERFLEESIDI 84134
84135 KGSDYRVLPFGAGRRVCPGAQLGISLVASMIGHLLHQFTWALQDGTRPEDLDMMESPGLV 84314
84315 TFMATPLQVVAMPRLDKEELFKRVPVDMS* 84404
 
CYP98A16P   rice
      aaaa01016100.1 CYP98A16P (indica cultivar-group) 
      ortholog AC105377.3 $P like 98A3 chr 10 94%
5606 LPPGPRAWPVVGNLFDITPVRCRCFMEWADKYGPIMTVWLGTSPTIVVSTSELAREVFKN 5785
5786 NDQQLADRPRNHSAERLSRGGTDLIWADYGPHYVKVRKLCNLELFAPRRMEALRPIREDE 5965
5966 VTAMVESI 5989
 
AC105377.3 $P CYP98A16P like 98A3 chromosome 10 clone OSJNBa0034E15 probable pseudogene 5 frameshifts
identical to AC093612.17a chromosome 10 66530-69946 
3339 MDTPALLPLALALVAIPITILLDLQSDPPRQAVPRAPGVAGGNLFDITLVRCRCFMEWAG 3160
3159 KYGPIMTVWLGTSPTIVVSTSELAREVFKNV 3067 (frameshift)
3065 NDQQLADRPRNHSAERLSRGGTDLIWADYGPHYVKVRKLCNLELFAPRRMEALRPIS 2895
2894 EDEVNAMVESIYRAVTAP 2841 (1)
969 GEEGKPIGVRKHLSMVAFNNITRLTFGKRFIVAAGELDEQGCEQKAIVKAGIKIGASLPI 790
789 AEHILVLRWLNLVDEELYNAHSARRDRFTRRIMDEHARELERHGAKQHFV 640 (frameshift)
641 FTLRDQYDLSDDTV 600 (frameshift)
598 VIGLLWDMIAAGSDTAVITAEWAMAELVRNPRVQMKAQEELDRVIGRGRVMLEADIPNLP 419
418 YLQAVVKESFRLHTPTPLMLPHKASA 341
341 RVKIAGYD 318 (frameshift)
317 VPKGANVIVNVWAVGRDLSVWDSPLP 240 (frameshift)
240 PLEYRPERFLEESIDIKGSDYRVLPFGAGRRVCPGAQLGISLVASMIGHLLHQFTWALPD 61
60  GTWPEDLDMMESSGLVTFMA 1
25696 TPLQVVAMPRLDKEELFKRVPVDMS* 25773 from AC093612.17
 
aaaa01032717.1 CYP98A16P (indica cultivar-group) 
ortholog AC105377.3 $P like 98A3 chr 10 99%
see aaaa01016100.1 for ortholog
 484 GEEGKPIGVRKHLSMVAFNNITRLTFGKRFIVAAGELDEQGCELKAIVKAGIKIGASLPI 663664     
     AEHILVLRWLNLVDEELYNAHSARRDRFTRRIMDEHARELERHGAKQHFVDALFTLR
 835 DQYDLSDDTVIGLLWDMIAAGSDTAVIMAEWAMAELVRNPRVQMKAQEELDRVIGRGR 1008
1009 VMLEADIPNLPYLQAVVKESFRLHPPTPLMLPHKAS 1116
1101 PTQGQRRVKIAGYDVPKGANVIVNVWAVGRDLSVWDSP 1214
1220 LEYRPERFLEESIDIKGSDYRVLPFGAGRRVCPGAQLGISLVASMIGHLLHQLTWALPD 1399
1400 GTWPEDLDMMESPGLVTFMATPLQVVAMPRLDKEELFKRVPVDM 1531

CYP98A17  rice
     aaaa01028453.1 CYP98A17 (indica cultivar-group) 66% to 98A3
     91% to AC105377.11
365 GVTFIDAAGELDEQGCELKA
425 IVKDGIKIGASVPIAEHIPVLRWLNLVDEELYNAHSARRDRFTRRIMDEHARELERH 595
596 GAKQHFVDALFTLRDQYDLSDDTVIGLLWDMIAAGSDTAVITAEWAMAE 742
743 LARNPRVQAMAQEELDRVVGRGRLMLEVDIPNLPYLQAIVKESLRLHPPAPLMLPHKASA 922
923 GVKIAGYDVPKGANVIVNVWAVGRDPSVWDSPLEYRPERFLEESIDIKGSDYRVVPFGAG 1102
1103RRVCPGAQVGISLVASMIGHLLHQFTWALPDGTRPEDLDMME 1228
SPGLVTFMATPLQVVAMPRLDKEELFKRVPVDIS*
 
no japonica ortholog found 9/12/02
 
CYP98A18    rice
     aaaa01024345.1 CYP98A18 (indica cultivar-group) 76% to CYP98A4
1816 MDTPALLPLALALVAIPIVILLFNRIRPGRLPPGPRAWPVVGNLFDIHPVRCRCFMEWAGKYG 1628
1627 PIMTVWLGTSPTVVVSTSELAREVLKNNDQQLADRPRNRSSERFSRGGVDLIWADYGPH 1451
1450 YIKVRKLCNLELFAPRRMEALRPIREDEVTAMVESIYRAITAPGR*YSTMN 1298
 
no japonica ortholog found 9/12/02
 
     aaaa01071198.1 CYP98A18 (indica cultivar-group) 75% to CYP98A4 AC108505.1 $F
98% to aaaa01024345.1 
363 LPLALALVAIPIAILLFNRIRRGRLPPGPRAWPVVGNLFDIHPVRCRCFMEWAGKYGPII 542
543 TVWLGTSPTVVVSTSELAREVLKNNDQQLADRPRNRSSERFSRGGVDLIWADYGPHYIKV 722
723 RKLCNLELFAPRRMEALRPI 782
 
no japonica ortholog found 9/12/02

CYP98A19 pinus taeda
         GenEMBL AY064170
         Anterola,A.M., Jeon,J.H., Davin,L.B. and Lewis,N.G.
         Transcriptional control of monolignol biosynthesis in Pinus taeda:
         factors affecting monolignol ratios and carbon allocation in
         phenylpropanoid metabolism
         J. Biol. Chem. 277 (21), 18272-18280 (2002)

CYP98A20 Sesamum indicum
         GenEMBL AY065995 
         p-coumarate 3-hydroxylase mRNA
         Anterola,A.M., Jeon,J.H., Davin,L.B. and Lewis,N.G.
         Transcriptional control of monolignol biosynthesis in Pinus taeda:
         factors affecting monolignol ratios and carbon allocation in
         phenylpropanoid metabolism
         J. Biol. Chem. 277 (21), 18272-18280 (2002)

99A Subfamily

CYP99A1      Sorghum bicolor
                GenEMBL AF029857
                Soren Bak, Rachel Alice Kahn, Hanne Linde Nielsen, Birger
                Lindberg Moller, Barbara Ann Halkier
                Cloning of three A-type cytochromes P450, CYP71E1,
                CYP98, and CYP99 from Sorghum bicolor (L.) Moench by
                a PCR approach and identification by expression in
                Escherichia coli of CYP71E1 as a multifunctional
                cytochrome P450 in the biosynthesis of the cyanogenic
                glucoside dhurrin.
                Plant Molecular Biology 36, 393-405 (1998).

CYP99 is the last name assigned for plants under the 100 mark.
After this, we move to CYP701 and continue from there.  

701A Subfamily

CYP701A1    Cucurbita maxima (pumpkin)
            no accession number
            Pierre Bilodeau
            submitted to nomenclature committee
            called 11a
            77% to 701A3
            note: this sequence is 79% identical to AF212990.  It is not 
            the same sequence.  The authors have swapped names.

CYP701A1    Cucurbita maxima (pumpkin)
            GenEMBL AF212990
            Helliwell,C.A., Olive,M.R., Gebbie,L., Forster,R., 
            Peacock,W.J. and Dennis,E.S.
            Isolation of an ent-kaurene oxidase cDNA from Cucurbita maxima
            Aust. J. Plant Physiol. 27, 1141-1149 (2000)

CYP701A2    Cucurbita maxima (pumpkin)
            no accession number
            Pierre Bilodeau
            submitted to nomenclature committee
            called 11b
            note: this sequence is actually the same as the AF212990 sequence
            even though the authors name that seq 701A1.  They have apparently
            swapped the two names.  

CYP701A3   Arabidopsis
           GenEMBL AF047719-AF047721 AC005405|
           Helliwell, C.A., Sheldon, C.C., Olive, M.R., Walker, A.R., 
           Zeevaart, J.A.D., Peacock, W.J. and Dennis, E.S.
           Cloning of the Arabidopsis ent-kaurene oxidase gene GA3.
           Proc. Natl. Acad. Sci. USA  95, 9019-9024 (1998)
           catalyzes the oxidation of ent-kaurene to ent-kaurenoic acid in the 
           gibberellin biosynthetic pathway
           66% identical to 701A1 and 701A2 (partial sequences)
           73% identical to 701A4 EST

CYP701A4   Capsicum annuum (hot pepper)
           GenEMBL AA840770 (257bp)
           Hong,S.T., Chung,J.E., An,G. and Kim,S.R.
           Analysis of 176 expressed sequence tags generated from cDNA clones
           of Hot pepper by single-pass sequencing.
           Unpublished (1998)
           clone pfb1-22 5'
           CFB14 Floral bud cDNA library of Hot pepper cDNA
           73% identical to 701A3
           ITEEKLCQLPYLSAVFHETLRKYSPAPIVPLRYVHEDTQLGGYHVPEGT
           EIAINIYGCNRDKKVWESPDEWKPERFLEGKYDPMD

CYP701A5  Stevia rebaudiana (Stevia)
          No accession number
          Jim Brandle
          Submitted to nomenclature committee Jan. 23, 2001
          59% to 701A1

CYP701A6  rice 
#50 = #52 with alt exon 1 reduce gene count by one
>aaaa01001279.1 CYP701A6 (indica cultivar-group) ortholog of AP005302.1a
AVPGLPIIGNLHQLKE 20880
20881 KKPHQTFAKWAEIYGPIYTIRTGASSVVVLNSTEVAKE 20994
 
>AP005302.1a CYP701A6 (japonica cultivar-group) chromosome 6 = AC087597.1a 
N-terminal missing
identical to AC087597.1c (duplicate)
66118 MESLLAAGAGGIGVAAAAVGGFIAAATLAVAPPKNRRNPPP 65996 (1) (from AC087597.1a)
     AVPGLPIIGNLHQLKE 2571
2572 KKPHQTFAKWAEIYGPIYTIRTGASSVVVLNSTEVAKE 2685
2780 AMVAKFSSISTRKLSKALTVLTRDKSMVATSDYCDFHKMVKRYVMSSMLGTSAQ 2950 (0?)
3102 FRDIRDMMIHNMLSTFHKLVKDDPHAPLIFRDVFKDELFRLSMIQ 3236
3320 SLGEDVSSVYVDEFGRDISKEEIYNATVTDMMMCAIEVDWRDFFPYLSWVPNKSFETR 3493
3494 VFTTETRRTAVMRALIKQQKERIVRGE 3574
3691 AKTCYLDFLLAENTLTDEQLMMLVWEALIEAADTTLVTTEWAMYELAKNPDKQ (0)
     ERLYQEIREVCGDETVTEEHLPRLPYLNAV 4038
4039 FHETLRRHSPVPLIPPRFVHEDTKLAGYDVPAGTE 4143
4711 MVINLYGCNMNRKEWESPEEWVPERFAGGRLEVADMYKTMAFGAGRRACAGSLQATHIA 4887
4888 CAAVARFVQEFGWRLREGDEEKVDTVQLTAYKLHPLHVHLTRRGRM 5025
 
#52 = #50 with alt exon 1 reduce gene count by one
>aaaa01001279.1b CYP701A6 (indica cultivar-group) orth of AC087597.1c
may be alternative first exons 
14994 MEAFVPGGAGAAAAAVGGFVAAAALAERAGVIARAGVIAPP 15116
16019 PGGVGAAAVAAVGGWVCRCGRARAGVIAPRKRSNAPP 16129 alt exon 1
20833 AVPGLPIIGNLHQLKEKKPHQTFAKWAEIYGPIYTIRTGASSVVVLNSTEVAKE 20994
21089 AMVAKFSSISTRKLSKALTVLTRDKSMVATSDYCDFHKMVKRYVMSSMLGTSA 21247
21408 QFRDIRDMMIHNMLSTFHKLVKDDPHAPLIFRDVFKDELFRLSMIQ 21545
22891 SLGEDVSSVYVDEFGRDISKEEIYNATVTDMMMCAIEVDWRDFFPYLSWVPNKSFETR 23064
23065 VFTTETRRTAVMRALIKQQKERIVRGE 23145
23262 AKTCYLDFLLAENTLTDEQLMMLVWEALIEAADTTLVTTEWAMYELAKNPDKQ 23420
23519 ERLYQEIREVCGDETVTEEHLPRLPYLNAVFHETLRRHSPVPLIPPRFVHEDTKLAGYD 23695
23696 VPAGTE 23713
24281 MVINLYGCNMNRKEWESPEEWVPERFAGGRLEVADMYKTMAFGAGRRACAGSLQATHIA 24457
24458 CAAVARFVQEFGWRLREGDEEKVDTVQLTAYKLHPLHVHLTRRGRM 24595
 
>AC087597.1c $F CYP701A6 chromosome 1 clone OSJNba0088C22 N-terminal exon =  AU163509.1
CYP703A1 like, BE039821.1 OC08F06 OC cDNA 5' similar to ga3.Length = 993 59% to 701A3 same as AP005302.1a with different N-term
128653 MEAFVPGGAGAAAXAVGGFVAAAALAERAGVIAPRKRPNAPP 128781 (1) alt exon 1
129691 PGGVGAAAVAAVGGFVAAAALAERAGVIAPRKRSNAPP 129807 (1) alt exon 1
131498 MEAFVPGGAGAAAPAVAAVGGFVAAAALAERAGVIAPRKRTNAPP 131632 (1) 
134410 AVPGLPIIGNLHQLKEKKPHQTFAKWAEIYGPIYTIRTGASSVVVLNSTEVAKE 134571 (0)
134666 AMVAKFSSISTRKLSKALTVLTRDKSMVATSDYCDFHKMVKRYVMSSMLGTSAQ 134827 (0)
134988 FRDIRDMMIHNMLSTFHKLVKDDPHAPLIFRDVFKDELFRLSMIQ 135122 (0)
135206 SLGEDVSSVYVDEFGRDISKEEIYNATVTDMMMCAIEVDWRDFFPYLSWVPNKSFETRV 135382
135383 FTTETRRTAVMRALIKQQKERIVRGE 135460 (0)
135577 AKTCYLDFLLAENTLTDEQLMMLVWEALIEAADTTLVTTEWAMYELAKNPDKQ 135747 (0)
       ERLYQEIREVCGDETVTEEHLPRLPYLNAV 135924
135925 FHETLRRHSPVPLIPPRFVHEDTKLAGYDVPAGTE 136029 (0)
136597 MVINLYGCNMNRKEWESPEEWVPERFAGGRLEVADMYKTMAFGAGRRACAGSLQATHIA 136773
136774 CAAVARFVQEFGWRLREGDEEKVDTVQLTAYKLHPLHVHLTRRGRM* 136914
 
CYP701A7  rice
#51
>aaaa01001279.1a CYP701A7 (indica cultivar-group) orth of AC087597.1b
lower case from AC087597.1b
2252 MEAFVSGGAGGVGAAAVVGVFVAAAVVGGFVAAVALAERAGVIAPRKRPNAPP 2410
4150 AVPGLPIIGNLHQLKEKKPHQTFTKWAEIYGPIYTIRIGASSVVVLNSTEVAKE (0)
     AMVAKFSSISTRKLSKALTVLTRDKSMVA 4509
4510 TSDYGDFHKMVKRYVMSSTLGTSAQ 4584
     FRDTRDMMINNM 4780
4781 LSTFHKLVKDDPHVPLIFRDVFKDELFRLSMIQ 4879
4963 SLGEDVSSVYVDEFGRDISKEEIYNATVTDMMMCAIEVDWRDFFSYLSWVPNKSFETR 5136
5137 VFTAEARRTAVMRALIKQQKERIVRGE
     AKICYLDFLLAENTLTDEQLTMLVWEELIEAADTTLVATEWAMYELAKNPDKQ 6765
     erlyqeirEVCGDETVTEEHLPRLPYLNAVF 6945
6946 HETLRRHSPVPLIPPRFVHEDTKLAGYDVPAGTE 7047
7790 MVINLYGCNMNKKEWESPEEWVPERFTGGRLEVADMYKTMAFGAGRRACAGSLQVMHIA 7966
7967 CTAIARFVQEFGWRLTEGDEEKVDTVQFTAYKLHPLHVHLTPRGRM 8104
 
>AC087597.1b $F CYP701A7 chromosome 1 clone OSJNba0088C22 = AP005302.1b 
CYP703A1 like may be alternative N-terminal exons
115151 MEAFVSGGAGGVGAAAVVGVFVAAAVVGGFVAAVALAERAGVIAPRKRPNAPP 115309 (1)
116986 AVPGLPIIGNLHQLKEKKPHQTFTKWAEIYGPIYTIRIGASSVVVLNSTEVAKE 117147 (0)
       AMVAKFSSISTRKLSKALTVLTRDKSMVATSDYGDFHKMVKRYVMSSTLGTSAQ 117420 (0)
117581 FRDTRDMMINNMLSTFHKLVKDDPHVPLIFRDVFKDELFRLSMIQ 117715 (0)
117799 SLGEDVSSVYVDEFGRDISKEEIYNATVTDMMMCAIEVDWRDFFSYLSWVPNKSFETRV 117975
117976 FTAEARRTAVMRALIKQQKERIVRGE 118053 (0)
119442 AKICYLDFLLAENTLTDEQLTMLVWEELIEAADTTLVATEWAMYELAKNPDKQ 119612 (0) 
119689 ERLYQEIREVCGDETVTEEHLPRLPYLNAVFHETLRRHSPVPLIPPRFVHEDTKLAGYD 119865
119866 VPAGTE (0)
120626 MVINLYGCNMNKKEWESPEEWVPERFTGGRLEVADMYKTMAFGAGRRACAGSLQVMHIA 120802
120803 CTAIARFVQEFGWRLTEGDEEKVDTVQFTAYKLHPLHVHLTPRGRM* 120943
 
CYP701A8 rice
#162
>aaaa01004604.1 $FI CYP701A8 (indica cultivar-group) 52% to 701A3 ortholog of AF088220 AP005302.1c
4885  MESMLVAGAGAAAVAAVGGLVAAAALADKLVAAPPPRKNRANPPP 5019 (1)
8461  AVPGLPIIGNLHQLKEKKPHQTFAKWSETYGPIYTIKTGASPVVVLNSTEVAKE (0?) 8622
9972  AMIDKFSSISTRKLPKAMSVLTRKSMVAISDYGDYQKMAKRNIMIGMLGFNAQ (0?) 10136
10237 FRGTRERMISNVLSTLHKLVSLDPHSPLNFRDVYINELFSLSLIQ (0?) 10371
10526 SLGEDVSSVYVEEFGREISKDEIFDVLVHEMMMCAVEADWRDYFPYLSWLPNKSFDTIVSTTEFR
10721 RDAIMNALIKKQKERIARGE (0)
10866 ARASYIDFLLEAERSAQLTDDQLMLLLSESILAAADTVLVTTEWTMYEIAKNPDKQ (0) 11033
11380 ELLYQEIREACGGEAVTEDDLPRLPYLNAVFHETLRLHSPVPVLPPRFVHDDTTLAGYD 11556
11557 IAAGTQMMINVYACHMDEKVWESPGEWSPERFLGEGFEVADRYKTMAFGAGRRTCAGSLQ 11736
11737 AMNIACVAVARLVQELEWRLREGDGDKEDTMQFTALKLDPLHVHLKPRGRM* 11892
 
>AP005302.1c $F CYP701A8 (japonica cultivar-group) chromosome 6 
AF088220 48% to 701A3 mRNA BF430785 OG04F06T3
51052 MESMLVAGAGAAAVAAVGGLVAAAALADKLVAAPPPRKNRANPPP (1) 51186
      AVPGLPIIGNLHQLKEKKP 54671
54672 HQTFAKWSETYGPIYTIKTGASPVVVLNSTEVAKE (0?)
56126 AMIDKFSSISTRKLPKAMSVLTRKSMVAISDYGDYQKMAKRNIMIGMLGFNAQ (0?) 56290
56388 FRGTRERMISNVLSTLHKLVSLDPHSPLNFRDVYINELFSLSLIQ (0?) 56525
56680 SLGEDVSSVYVEEFGREISKDEIFDVLVHEMMMCAVEADWRDYFPYLSWLPNKSFDTIV 56856
56857 STTEFRRDAIMNALIKKQKERIARGE (0?)
57020 ARASYIDFLLEAERSAQLTDDQLMLLLSESILAAADTVLVTTEWTMYEIAKNPDKQ (0) 57187
57534 ELLYQEIREACGGEAVTEDDLPRLPYLNAVFHETLRLHSPVPVLPPRFVHDDTTLAGYD 57710
57711 IAAGTQMMINVYACHMDEKVWESPGEWSPERFLGEGFEVADRYKTMAFGAGRRTCAGSLQ 57890
57891 AMNIACVAVARLVQELEWRLREGDGDKEDTMQFTALKLDPLHVHLKPRGRM* 58046
 
note this is in a gene cluster with at least 4 genes
 
CYP701A9 rice
#261
>aaaa01009744.1 CYP701A9 ortholog to AP005302.1d 100%
9058 QAMIEKFSSISTKKLPKALSVISRKNMVSISDYGDFYKMAKRNIMLAILGFNAQ
     FCDTRERMVSNVLSSLHKLVAVDPHSPLNF 8699
8698 REVYTTELFGLSLIQ 8654
8451 QNLGEDVCSVYVEEFGREISKEEIFHVLVHEILSCVVEPDWRDYFPYLSWLPNKSFETIV 8272
8271 SSTEFRRDAVMNALIKRQKERIARGE
     ARISYIDFLLEAKNSTQLTDHQLMLLLAESIAAAVDTVLVTTEWAMYELAK 7912
7911 NPDKQ
     EWLYREIREVCGGK 7732
7731 AVTEEDLPRLPYLDAVLHETLRLHSPVPVLPTRFVHDDTTLAGYDVPAGTQVMINVFGCH 7552
7551 MDEEAWESPGEWSPERFLGEGFKLADRYKTLAFGAGRRTCAGSQQAVSIACVAIARFVQE 7372
7371 LQWTLREGDGDKEDTMQYTALKLHPLHVHLKPRG 7270
 
>AP005302.1d CYP701A9 (japonica cultivargroup) chr 6 ortholog to AAAA01009744.1 
88169 MESLLAAGAGGIGVAAAAAVVAATLAVVPPKDRGNNPPP 88285 (1)
      AVPGLPVIGNMHQLKEKK 91433
91434 PHHTFTKWSKTYGPIYTIKTGASSVVVLNSTEVAKE 91541 (0?)
96519 QAMIEKFSSISTKKLPKALSVISRKNMVSISDYGDFYKMAKRNIMLAILGFNAQ (0?)
      FCDTRERMVSNVLSSLHKLVAVDPHSPLNF 96878
96879 REVYTTELFGLSLIQ (0) 96923
97128 NLGEDVCSVYVEEFGREISKEEIFHVLVHEILSCVVEPDWRDYFPYLSWLPNKSFETIV 97304
97305 SSTEFRRDAVMNALIKRQKERIARGE
      ARISYIDFLLEAKNSTQLTDHQLMLLLAESIAAAVDTVLVTTEWAMYELAK 97664
97665 NPDKQ (0) gc boundary
      EWLYREIREVCGGK 97844
97845 AVTEEDLPRLPYLDAVLHETLRLHSPVPVLPTRFVHDDTTLAGYDVPAGTQVMINVFGCH 98024
98025 MDEEAWESPGEWSPERFLGEGFKLADRYKTLAFGAGRRTCAGSQQAVSIACVAIARFVQE 98204
98205 LQWTLREGDGDKEDTMQYTALKLHPLHVHLKPRG 98306
 
#261
>aaaa01015940.1 CYP701A9 (indica cultivar-group) orth AP005302.1d chr 6 100%
see aaaa01009744.1 above for ortholog
3349 PGLPVIGNMHQLKEKKPHHTFTKWSKTYGPIYTIKTGASSVVVLNSTEVAKEV 3507

CYP701A10 Pisum sativum (pea)
          No accession 
          Sandra Davidson
          Pea LH gene PsKO1 from Pisum sativum  cv Torsdag
          Submitted to nomenclature committee Feb. 26, 2003
          61% to 701A3

702A Subfamily

CYP702A1     Arabidopsis thaliana
            GenEMBL AC001229 (109560bp), AC007234 comp(19575-21432)
            F5I14.20 from an Arabidopsis genome project at 
            http://pgec-genome.pw.usda.gov/F5I14.anno.html
            submitted by Brian Osborne, Plant Gene Expression Center, Albany CA

CYP702A2    Arabidopsis thaliana
            GenEMBL Z97338 seq. (a) nucleotides (comp. 95383-97405)
            C-terminal sequence 

CYP702A2    Arabidopsis thaliana
            GenEMBL AL161541  
            CDS complement(join(48843..48945,49052..49179,49280..49462,
            49561..49939,49986..50137,50272..50576,50655..50868))

CYP702A3    Arabidopsis thaliana
            GenEMBL Z97338 seq. (b) nucleotides 101369-104695
            Complete sequence 

CYP702A3    Arabidopsis thaliana
            GenEMBL AL161541  
            CDS join(55618..55863,56597..56746,56839..57177,57252..57330,
            58549..58709)

CYP702A4P   Arabidopsis thaliana
            GenEMBL Z97338 seq. (d) nucleotides 126846-126941
            lone exon sequence 

CYP702A5    Arabidopsis thaliana
            GenEMBL Z97338 seq. (h) nucleotides 168806-171661
            Complete sequence 
            GSS AQ249305, B24420

CYP702A6    Arabidopsis thaliana
            GenEMBL  Z97338 seq. (i) nucleotides 172246-175058
            Complete sequence

CYP702A7P   Arabidopsis thaliana
            GenEMBL Z97338 seq. (j) nucleotides 176173-176280
            lone exon sequence 

CYP702A8    Arabidopsis thaliana
            GenEMBL AP001314 comp(11921-14547)

703A Subfamily

CYP703A1    Petunia x hybrida (petunia)
            GenEMBL AB006790
            Imaishi,H., Matsumoto,Y., Ishitobi,U. and Ohkawa,H.
            Encoding of a cytochrome P450-dependent lauric acid monooxygenase
            by CYP703A1 specifically expressed in the floral buds of petunia
            hybrida
            Biosci. Biotechnol. Biochem. 63 (12), 2082-2090 (1999)
            IMT-2

CYP703A2    Arabidopsis thaliana
              GenEMBL AC023628 comp(16084-17699)
              75% to 703A1 EST AA720028

704A Subfamily

CYP704A1      Arabidopsis thaliana
            GenEMBL AC002388 ESTs: AA597388
            Complete sequence 

CYP704A2     Arabidopsis thaliana
            GenEMBL AC003680 F17K2.4
            ESTs AA597388

CYP704B1    Arabidopsis thaliana
           GenEMBL AC073178.3 68191-70140
           chromosome I clone IGF-F10D13 
           42% to 704A2, 39% to 86A1, 38% to 86A7, 38% to 86A8, 38% to 94D1
           ESTs AA728483

705A Subfamily

CYP705A1      Arabidopsis thaliana
            GenEMBL Z97338 seq. (c)  nucleotides (comp. 116171-117782) 
            Complete sequence ESTs T21786

CYP705A1    Arabidopsis thaliana
            GenEMBL AL161541  
            CDS complement(join(69643..70278,70337..71254))

CYP705A2      Arabidopsis thaliana
            GenEMBL Z97338 seq. (e)  nucleotides 127652-128588
            Complete sequence no ESTs

CYP705A2    Arabidopsis thaliana
            GenEMBL AL161541  
            CDS join(81073..81972,82054..82683)

CYP705A3      Arabidopsis thaliana
            GenEMBL Z97338 seq. (f)  nucleotides 134833-136422
            Complete sequence no ESTs

CYP705A3      Arabidopsis thaliana
            GenEMBL B97399 
            T33J16TF BAC end GSS fragment
            Contig 1531 of the TIGR Landsberg erecta sequences has 95% match 4 diffs

CYP705A3    Arabidopsis thaliana
            GenEMBL AL161541  
            CDS join(88305..89222,89307..89972)

CYP705A4      Arabidopsis thaliana
            GenEMBL Complete sequence Z97338 seq. (g)  nucleotides 153425-155024
            GenEMBL X94366 same gene with some frameshifts
            no ESTs

CYP705A4    Arabidopsis thaliana
            GenEMBL AL161541  
            CDS join(<107002..107787,107864..108511)

CYP705A5     Arabidopsis thaliana
            GenEMBL AB017064 9827-11417 region
            Identical with ESTs N97058, T04417, T04613, T45789, T43499, T12851

MASMITVDFENCF
IFLLLCLFSRLSYDLFFRKTKDSRAGCALPPSPPSLPIIGHLHLILFVPIHQSFKNISS 
KYGPLLHLRFFNFPIVLVSSASTAYEIFKAQDVNVSSRPPPPIEESLILGSSSFINTPYG 
DYSKFMKKFMVQKLLGPQALQRSRNIRADELERFYKTLLDKAMKKQTVEIRNEAM 
KLTNNTICKMIMGRSCSEENGEAETVRG
LVTESIFLTKKHFLGAMFHKPLKKLGIS
LFAKELMNVSNRFDELLEKILVEHEEKLQEHHQTSDMLDMLLEAYGDENAEYKITRDQIKSLFV
DLFSAGTEASANTIQWTMAEIIKNPKICE
RLREEIDSVVGKTRLVQETDLPNLPYLQAIVKEGLRLHPPGPVVRTFKETCEIKGFYI 
PEKTRLFVNVYAIMRDPDFWEDPEEFKPERFLASSRLGEEDEKREDMLKYIPFGSGRRAC 
PGSHLAYTVVGSVIGMMVQHFDWIIKGEKINMKEGGTMTLTMAHPLKCTPVPRNLNT* 

CYP705A6     Arabidopsis thaliana
             GenEMBL AC007018 54370-57998 B97581 GSS fragment BAC end
             72% identical to 705A3

CYP705A7X    Arabidopsis thaliana
             GenEMBL B97148
             GSS fragment BAC end T32F24TR identical to B97150
             EST T42559 short exact match on end. EST retains intron
             705A7 was chimeric.  It has been completed and renamed 
             CYP705A30 and CYP705A32

CYP705A7X    Arabidopsis thaliana
             GenEMBL B97150
             GSS fragment BAC end T32G12TR identical to B97148
             EST T42559 short exact match on end. EST retains intron
             705A7 was chimeric.  It has been completed and renamed 
             CYP705A30 and CYP705A32

CYP705A8    Arabidopsis thaliana 
            GenEMBL AC005623 complement(22950..23582,23659..24570)
            gene T20P8.5 no ESTs no GSSs

CYP705A9    Arabidopsis thaliana 
            GenEMBL AC005623 comp(25711..26361,26438..26915,26962..27329)
            gene T20P8.6 no ESTs no GSSs

CYP705A10P    Arabidopsis thaliana 
            GenEMBL AB017064 
            lone exon 1, no more of this gene is found
            end is identical to first 13 amino acids of EST W43443
       81801 MNFDFQNLFILILLCLLSVLCYSLFFKKPKDGFNLPPSPPSLPIIGH 81661

CYP705A11P    Arabidopsis thaliana 
            GenEMBL AB017064 comp(12233-12054)
            mid region 155-213  64% to 705A8 lone exon 
            no more of this gene is found
            NIYKNLVRSYTSLLDKAMMNESIDENGKEA
            MKLINNNIYKMIMGRISSKENGEAKRFKGL

CYP705A12     Arabidopsis thaliana
            GenEMBL AB022210 18214-16643 region (-) strand 
            64% to 705A3 no ESTs no GSSs (2/23/99)

CYP705A13        Arabidopsis thaliana
            GenEMBL AC007197 comp(7079-8717) 
            ESTs T42861, T43276, AA395378 no GSSs

CYP705A14P Arabidopsis thaliana
            GenEMBL AP000383 27367-27973
            5-36 followed by a large gap then 414-550
            clone MAL21

CYP705A15 Arabidopsis thaliana
            GenEMBL AP000383 29031-30681
            clone MAL21 
            identical to GSS AL090622

CYP705A16 Arabidopsis thaliana
            GenEMBL AP000383 32158-33813
            clone MAL21
            91% identical to F19864 89% identical to F19802

CYP705A17P Arabidopsis thaliana
            GenEMBL AP000383 34749-35590
            14-271 then 222 amino acid gap followed by 494-519
            clone MAL21

CYP705A18 Arabidopsis thaliana
            GenEMBL AP000383 36850-38505
            clone MAL21

CYP705A19 Arabidopsis thaliana
            GenEMBL AP000383 39232-40867
            clone MAL21
            ESTs F19802, F19864

CYP705A20 Arabidopsis thaliana
            GenEMBL AP000383 41713-43331
            clone MAL21
            GSS AL088383 no ESTs

CYP705A21   Arabidopsis thaliana
            GenEMBL AP000383 44386-46007
            clone MAL21
            GSS AL095325

CYP705A22   Arabidopsis thaliana
            GenEMBL AP000383 47200-48831
            clone MAL21
            ESTs T21800, R30233

CYP705A23   Arabidopsis thaliana
            GenEMBL AP000383 49393-51005
            clone MAL21

CYP705A24   Arabidopsis thaliana
            GenEMBL AC010155 47066-48677
            clone F3M18

CYP705A25   Arabidopsis thaliana
            GenEMBL AC012561 47417-49106 clone F11F12

CYP705A26P  Arabidopsis thaliana
            GenEMBL AC012561 49934-50863 clone F11F12
            pseudogene missing C-terminal

CYP705A27   Arabidopsis thaliana
            GenEMBL AC012561 52311-53952 clone F11F12
            EST W43443 no GSSs

CYP705A28   Arabidopsis thaliana 
            GenEMBL AP001304 13048-14798 same as AL091537 
            T7 end of BAC T8C3 = B77649

CYP705A29P  Arabidopsis thaliana
            GenEMBL AP001304 15786-16553

CYP705A30   Arabidopsis thaliana
            GenEMBL AP001304 15786-16553 part of old 705A7X

CYP705A31P  Arabidopsis thaliana
            GenEMBL AP001304 20651-20824

CYP705A32   Arabidopsis thaliana
            GenEMBL AP001304 21561-23630 Identical to B74035 part of old 705A7X

CYP705A33   Arabidopsis thaliana
            GenEMBL AP001304 24249-25900 2 amino acid diffs with B96118

CYP705A34   Arabidopsis thaliana
           GenEMBL AP002033 CDS join(14214..14717,14798..15391) 
           gene_id:F1M23.3
           81% to 705A13 Missing start codon may be a pseudogene

706A Subfamily

CYP706A1 Arabidopsis thaliana
            GenEMBL AL021635
            T12H17.80
            most like 93A1 (37% identical)
            ESTs T46392, T44621, T46193, N65907
            These ESTs could be either 706A1 or 706A2 T21057, T76384, Z24511,
            AA395860, AA597583, AA597644

CYP706A2 Arabidopsis thaliana
            GenEMBL AL021635
            T12H17.100
            most like 93A1 (37% identical)
            ESTs Z17966, 
            These ESTs could be either 706A1 or 706A2 T21057, T76384, Z24511,
            AA395860, AA597583, AA597644

CYP706A3    Arabidopsis thaliana
            GenEMBL AB024024 comp(50063-51694)
            K15C23
            no ESTs no GSSs
            56% identical to 706A1 and 706A2

CYP706A4    Arabidopsis thaliana
            GenEMBL AL080318 comp(42111-43787)
            T4C9.140 61% to 706A3
            GSS AL086483 no ESTs
            Contig 391 of the TIGR Landsberg erecta sequences has 100% match

CYP706A4    Arabidopsis thaliana
            GenEMBL AL161533
            CDS complement(join(165166..165789,165916..166842))

CYP706A5    Arabidopsis thaliana
            GenEMBL AL080318 comp(44693-46617)
            T4C9.150 65% t0 706A3
            no ESTs no GSSs

CYP706A5    Arabidopsis thaliana
            GenEMBL AL161533
            CDS complement(join(167748..168371,168734..169672))

CYP706A6    Arabidopsis thaliana
            GenEMBL AL080318 comp(49036-50528)
            T4C9.160 56% to 706A3
            no ESTs no GSSs

CYP706A6    Arabidopsis thaliana
            GenEMBL AL161533
            CDS complement(join(172091..172714,172867..173583))

CYP706A7        Arabidopsis thaliana
            GenEMBL AL080318 comp(51874-53756)
            T4C9.170 60% to 706A3
            no ESTs no GSSs

CYP706A7    Arabidopsis thaliana
            GenEMBL AL161533
            CDS complement(join(174929..175549,175876..176811))

CYP706A8    Matthiola incana (common stock)
            GenEMBL AF313492
            Eder,C.M. and Forkmann,G.
            Matthiola incana putative cytochrome P450
            Unpublished
            76% to 706A4

CYP706A9P   Lotus japonicus
            No accession number 
            Soren Bak and Susanne Paquette
            Submitted to nomenclature committee 4/10/2003
            60% to 706A7
            clone name CYP706APLT

CYP706B1       Gossypium arboreum (cotton)
             no accession number 
             Ping Luo and Xiao-Ya Chen
             Submitted to nomenclature committee 6/11/2000
             Sequence name LP132 47% identical to 706A5

CYP706B2       Gossypium arboreum (cotton)
             no accession number 
             Ping Luo and Xiao-Ya Chen
             Submitted to nomenclature committee 6/11/2000
             Sequence name LP64 44% identical to 706A6 58.6% identical to 706B1

707A Subfamily

CYP707A1      Arabidopsis thaliana (Thale Cress)
           GenEMBL AL021687 (T18B16.200)
           ESTs T43171
           this sequence is short for a P450 probably missing an exon in the translated 
           sequence.

CYP707A2        Arabidopsis thaliana
           GenEMBL AC005315
           gene T9I4.17
           62% identical to 707A1 GSS fragment B12307, no ESTs

CYP707A3       Arabidopsis thaliana
          GenEMBL AB020744
          85% identical to 707A1 no ESTs 
          note: last 22 amino acids are missing
          Contig 281 of the TIGR Landsberg erecta sequences has the C-terminal
          It is here also but with errors that make it hard to recognize

CYP707A4       Arabidopsis thaliana
          GenEMBL AP000419 comp(68986-71501)
          clone MVI11 from Kazusa Sept. 3, 1999
          GSSs B67654 AND B98253 no ESTs

708A Subfamily

CYP708A1      Arabidopsis thaliana (Thale Cress)
           GenEMBL AC002304 33000-35500 region
           GenEMBL AC004515
           simlar to CYP90 and CYP702 sequences

CYP708A2      Arabidopsis thaliana
           GenEMBL AB017064 comp(21958-19304) 53.7% to 708A1
           ESTs H76703, R90011, T13661, T45729, AA605413, AA713328

MSFVWSAAVWVIAVAAVVISKWLYRWSNPKCNGKLPPGSMGLPIIGETCDFFEPHGLYEISPFVKKRMLKX 
FRYGPLFRTNIFGSNTVVLTEPDIIFEVFRQENKSFVFSYPEAFVKPFGKENVFLKHGNIHK 
HVKQISLQHLGSEALKKKMIGEIDRVTYEHLRSKANQGSFDAKEXXXXX 
VIMAHLTPKIISNLKPETQATLVDNIMALGSEWFQSPLKLTTLISIYKVFIVSS 
ARRYALQVIKDVFTRRKASREMCGDFLDTMVEEGEKEDVIFNEESAINLIF
AILVVAKESTSSVTSLAIKFLAENHKALAELKXREHAAILQNRNGKGAGVSWEEYRHQMTFTNMVX 
VINETLRMANMAPIMYRKAVNDVEIKGYTIPAGWIVAVIPPAVHFNDAIYENPLEFNPWRWE 
GKELRSGSKTFMVFGGGVRQCVGAEFARLQISIFIHHLVTTYDFSLAQESEFIRAPLP 
YFPKGLPIKISQSL CYP708A3     Arabidopsis thaliana
              GenEMBL AB007260 16229-18271 
              ESTs Z34056, Z34880 opposite end of Z34056 outside coding region, Z46573

>CYP708A4    Arabidopsis thaliana
             GenEMBL AL353992.1 
             Chr III F14D17 
             58% to 708A2, 57% to 708A3 52% to 708A1
             Genbank translation is missing one exon with EXXR motif

709A Subfamily

CYP709A1   Arabidopsis thaliana (Thale Cress)
           GenEMBL AB005248 comp(67000-70500)
           most like Catharanthus roseus CYP72 L10081 
           (37% identical over 505 amino acids)

CYP709A2   Arabidopsis thaliana (Thale Cress)
           GenEMBL AC004146

709B Subfamily

CYP709B1   Arabidopsis thaliana (Thale Cress)
           GenEMBL AC004411 
           first P450 on cosmid

CYP709B2   Arabidopsis thaliana (Thale Cress)
           GenEMBL AC004411 
           second P450 on cosmid

CYP709B3   Arabidopsis thaliana (Thale Cress)
           GenEMBL AL035602 T29A15.200 
           matches EST N38616

CYP709B3   Arabidopsis thaliana (Thale Cress)
           GenEMBL AL161571 16 Mar 2000 709B3
           CDS join(139003..139285,139376..139599,139676..139923,
           140029..140401,140472..140900)

CYP709C1   Triticum aestivum (wheat)
           No accession number 
           Daniele Werck-Reichhart
           Clone name 431
           Submitted to nomenclature committee 3/29/2000
           48% to 709B2 and 709B3

CYP709C2   Triticum aestivum (wheat)
           No accession number 
           Daniele Werck-Reichhart
           Clone name 371
           Submitted to nomenclature committee 3/29/2000
           48% to 709B2

CYP709C3   Triticum aestivum (wheat)
           No accession number 
           Daniele Werck-Reichhart
           Clone name 111
           Submitted to nomenclature committee 3/29/2000
           47% to 709B2 and 709B3

710A Subfamily

CYP710A1      Arabidopsis thaliana (Thale Cress)
           GenEMBL AC004077 phase 1 seq. 16000-18000 region
           EST T44171
           note: this sequence is more like S. pombe Z98974 and CYP61 of yeast than 
           it is to other Arabidopsis sequences.  Like CYP51 it may cross kingdoms while
           retaining the same function.

CYP710A1      Arabidopsis thaliana (Thale Cress)
           GenEMBL AC004481

CYP710A2      Arabidopsis thaliana (Thale Cress)
           GenEMBL AC004077 phase 2 seq. comp(25221-26720)
           No ESTs

CYP710A2      Arabidopsis thaliana (Thale Cress)
           GenEMBL AC004481

CYP710A3     Arabidopsis thaliana (Thale Cress)
            GenEMBL AC005727 comp(56103-54667)
            77% identical to 710A1
            no ESTs

CYP710A4      Arabidopsis thaliana (Thale Cress)
             GenEMBL AC005727 comp(60965-59631)
             76% identical to 710A1
             no ESTs

711A Subfamily

CYP711A1        Arabidopsis thaliana 
           GenEMBL AC004484 comp(77000 -79417 region) AC004747 comp(8200-10000)   
           region
           note: this sequence has the best match to CYP5 thromboxane synthase of mammals
           it does not match other plant P450s.  It may be the CYP3 homolog in plants.
           no ESTs

712A Subfamily

CYP712A1      Arabidopsis thaliana (thale cress)
           GenEMBL AC002561
           most like CYP93A sequences
           no EST matches

CYP712A2      Arabidopsis thaliana (thale cress)
           GenEMBL AB010697 comp(19000-17400 region)
           no EST matches
           note July 16, 1999: This sequence lies adjacent to CYP93D1 on clone MOJ9
           The names of these two sequences were accidentally swapped
           This has now been corrected.  93D1 starts with MVDLQY
           CYP712A2 starts with MFTLNLDMNYTS

713A Subfamily

CYP713A1X  this sequence has been renamed CYP71A27
CYP713A2X  this sequence has been renamed CYP71A28

714A Subfamily

CYP714A1      Arabidopsis thaliana
            GenEMBL AF069716 43500-46500 region
            No ESTs, GSS sequence B96503 (661bp) F23A22TF

CYP714A2      Arabidopsis thaliana
            GenEMBL AF069716 47000-50000 region
            no ESTs

715A Subfamily

CYP715A1            Arabidopsis thaliana
           GenEMBL AB019226 44781 - 47206 AL083283 BAC end F6J7
           35% identical to 714A2

CYP715B1   Persea americana (avocado)
           GenEMBL AJ133717 C-terminal part only
           J. Pablo Zamorano
           58% to 715A1

716A Subfamily

CYP716A1           Arabidopsis thaliana
          GenEMBL AB018112 comp(38391- 34446)
          82% identical to second gene on this cosmid at 20509 - 22724
          34% identical to Synechocystis CYP120, 31% identical to CYP90A1

CYP716A2           Arabidopsis thaliana
          GenEMBL AB018112 (20509 - 22724)
          82% identical to second gene on this cosmid at comp(38391- 34446)

CYP717A1X         Hemerocallis hybrid cultivar (daylily)
             GenEMBL AF082028 (1373bp)
             Panavas,T., Pikula,A., Reid,P.D., Rubinstein,B. and Walker,E.L.
             Identification of senescence-associated genes from daylily
             Unpublished
             Name changed to CYP81J1

718A Subfamily

CYP718       Arabidopsis thaliana
            GenEMBL AC006931 comp(56081-57725)
            BAC "F7D19" 
            33% identical to 90A1
            no ESTs no GSSs see Arabidopsis P450 FASTA sequence list for the sequence

719A Subfamily

CYP719         Coptis japonica
           no accession number 
           Fumihiko Sato
           Submitted to nomenclature committee 3/21/99
           clone name CYPCJB

CYP720A1    Arabidopsis thaliana
            GenEMBL AC012396 comp(80036-82173) 
            contains a new family related to CYP90 in the 85 clan 
            38% to 90A1 but less to 90B1 and 90C1 
            no ESTs no GSSs 

CYP721A1    Arabidopsis thaliana
            GenEMBL AC013258 63642-65480 clone F9E10 
            GenEMBL AC025814.4  64213-66048
            new family in the 72 clan most like CYP72B 
            but not very similar to CYP72C chromosome I 
            GSSs B20052 B27750 no ESTs

CYP722A1    Arabidopsis thaliana
            GenEMBL AC024609 74483-77023 also AC025808 
            35% identical to CYP90A1

CYP723A1    Triticum aestivum (wheat)
            No accession number
            Daniele Werck-Reichhart
            Submitted to nomenclature committee 3/29/2000
            clone name 98i
            34% identical to 89A2

CYP724A1    Arabidopsis thaliana
            GenEMBL AL163817 62148-65132
            Translation in Genbank is not correct
            Chr 5 BAC clone F18O22 gene = F18O22_190
            In CYP85 clan 35% identical to 87A2

CYP725A1    Taxus cuspidata (Japanese yew)
            GenEMBL AF318211 
            Schoendorf,A., Rithner,C.D., Williams,R.M. and Croteau,R.B.
            Molecular cloning of a cytochrome P450 taxane 10beta-hydroxylase
            cDNA from Taxus and functional expression in yeast
            Proc. Natl. Acad. Sci. U.S.A. 98 (4), 1501-1506 (2001)
            5-alpha-taxadienol-10-beta-hydroxylase
            one of sdeveral P450s involved in taxol biosynthesis
            only about 30% identical to other named plant P450 families

CYP725A2    Taxus cuspidata (Japanese yew)
            GenEMBL AY056019.1
            Jennewein S., Rithner C.D., Williams R.M., Croteau R.B.
            Taxol biosynthesis: taxane 13alpha-hydroxylase is a cytochrome P450-
            dependent monooxygenase.
            Proc. Natl. Acad. Sci. U.S.A. 98:13595-13600(2001).
            64% identical to CYP725A1

CYP725A3    Taxus cuspidata (Japanese yew)
            GenEMBL AY188177
            Jennewein,S., Rithner,C.D., Williams,R.M. and Croteau,R.
            Taxoid metabolism: Taxoid 14beta-hydroxylase is a cytochrome
            P450-dependent monooxygenase
            Arch. Biochem. Biophys. 413 (2), 262-270 (2003)
            63% to 725A1 61% to 725A2

CYP726A1    Euphorbia lagascae 
            No accession number
            Edgar B. Cahoon, Kevin G. Ripp, Sarah E. Hall, and Brian McGonigle
            Submitted to nomenclature committee 4/17/2001
            Only 30% to 71A27 over 481 aa 43% to 71D4, 40% to 71D5 
            41% to 71D2, 41% to 71D1 less than 40% to other 71 subfamilies
            this sequence illustrates that 71D should probably have family 
            status

CYP727A1    Oryza sativa rice (japonica cultivar-group)
            GenEMBL AP003765.1 $F = AQ574081 = AP003832 37701-42682
140359 MASPCEHHVPYTLLGALLSGGGPHAAACGGAAFLRDYAERGTNALL
       WAALLAVTWLLVLRLAALLRLWALGARLPGPPAFPADPGLAAGDIT (1) 140634
142650 GYLSKLHGSYGPVVRLWLGPSQLLVSVKDSRVIKELLTKAEDKLPLTGKTYNLACGKLGLFISSFEK (0) 142851
143011 VKSRRESLKSFLDEKLSVGTGGSSFKIIQIVLDRVDSIMARDFLDCRYFSQHMAFNIVGSAL
       FGDAFFDWSDASAYEELMMTVAKDACFWASYAVPPFWKPDYRRYRTLCARLKLLTQGIVAKS
       RNQNGVLSLIDLSSCQRSERMIKDPCRGFSLLDGVISSRCLNEAAEGPLSSEEEICGNIMGL
       MLHGISTCANLIGNILTRLALYPNLQCQ 143652 (0)
144033 LHSEIVSGHSESSELKIDDVLRMKFLLATVCESARLLPAGPLLQRCSLQQ 144182 (1)
144578 DVNLNSSITIPAGAILVIPLHLVQMEASTWGNDACQFNPNRFLKKEINFE 144721 (1)
144825 EILAAAHKGSNGINLFTDECDKTESFLPFGSGSRACVGQKFAVLGIAMLIASLLRSYE 144992 (0)
145233 VQPHPALSQEMESLVDSNSLHHIPNPKIILKKRSI* 145340

CYP727A2   Hordeum vulgare  (barley)
           GenEMBL ESTs BJ471745.1 BF266636.3 BE437699.1 BF258552.1
           Might be chimeric 72% to rice 727A1
MAPSCGAAVPYTLLGALLGGGGGSYAPSWPACGGRAFLRDYARRGTNAMLWLALLAVTWV
LLRRIAALIRLWALGSRLPGPPALLADPGLAAVCRAGGDITGYLSXLHGSFGPIVRLWLG
PSQLLVSVKDAFLIKERLTKAEDKLPLTGRTYNLACGSLGLFISSFRKVKXX
RESLKVFLNEKLNVFASGSSFKIIEAVLRRTDSTKDIDSLDCRSFSQHIAFNIIGAALFGDVF
FDWSDAAAYEELLMVVAKDGCFWASYAVPPFWKPGYRRYRTLCAKLKILTEGIIRKSIDQ
NSALRHNSLSSSEGVVKDPVKCTSLLDGMISGRGFDGAVQGPLSSEEETCGNIVGLM
LHGISTSANLLCNILTRLVLYPKLKDQLYADIVAVHTESSELVIDDVLKMQFVLATICES
ARLLPAGPLLQRCSMQHDLTLKSSITIPAGAILVVPLHLV
QMDASIWGNDACQFNPNRLLQKDIDLGEILAAHKGSNGIKLFTECDKSDSFLPFGSGS
RACVGQKFAILGISLLVASLLHNYEVQPQPALYKEMGLEVDSSNLRHLPNPKTVLTKRKI

CYP727A3   Triticum aestivum 
           GenEMBL ESTs BE425375.1 BQ283398.1 BF201442.1 BQ281803.1
           Might be chimeric 68% to 727A1 rice
MAPSCGAAVPYTLLGALLSGGSYAPSWPACGGRAFLRDYAQRGTNAMLWLGFLAVTLVLL
RRIAALLRLWALGSRLPGPPALLADPGLAAVCRAGGDITGYLSKLHGSFGPIVRLWLGPS
QLLVSVKDASLIKEMLTKAEDKLPLTGRTYSLACGRLGLFISSFEKSKXXXX
TLNIFLNEKLNVAASESSFKIIEAVLHRTDSTKDKDSLDCRSFSQHMAFNIIGAALFGDV
LFDWSDAAAYEELLMVVAKDGCFWASYAVPPFWKPGYRRYRTLCAKLKILTESIIRKSID
QNGALRHNNLSSSKISEGVVKDPVRCTSLLDGMIXXXXXXXXXXXXXXXXXXXX
GKLMGLMLHGISASANLIGNILTKLVLSPELQDQLHVEIVSVCNESSKLEVDDLLRMQVL
LATVCESARLLPAGPLLQRCSLKHDLKLGSGITVPAQSILVVPLHLVQMDASVWGDDADQ
FNPHRFLKKDVDLREIFGAPKGSNRINVFSECAKTESFLPFGSGS
GNRACVGQKLAVLGISMLVASLLHSYEVQPQPALTKEMGLAVDSSNLRHLPNPKIILTKRKI

CYP736A1    Pyrus communis (pear)
            GenEMBL AF386512 
            El Sharkawy,I., Li,Z.G., Latche,A. and Lelievre,J.M.
            Ripening related genes in pear (Pyrus communis)
            Unpublished 
            54% to 736A2

CYP736A2    Lotus japonicus
            No accession number 
            Soren Bak and Susanne Paquette
            Submitted to nomenclature committee 4/10/2003
            54% to 736A1
            clone name CYP71BLT

CYP?       Cryptomeria japonica (Japanese cedar)
           GenEMBL AU036755
           Tsumura,Y., Suyama,Y., Yoshimura,K., Shirato,N. and Mukai,Y.
           Sequence-tagged-sites (STSs) of cDNA clones in Cryptomeria japonica
           and their evaluation as molecular markers in conifers
           Theor. Appl. Genet. 94, 764-772 (1997)
           This fragment is 54% identical to 76C1, 52% identical to 98A2 and 
           others
           The sequence is too short to name.

RLQLRHSPSLCSLMKPSEACKCWRIPCPEGTQLLVNIWEIHRDXAVWDRP
MEFIPERFVKSDTEIDVKGQDFELIPFGSGRRKCPGMPLAXTVISHTLGR
LLQSFEWFCPEGSEIDMTEGLGLSTPKSVPLEAIIKPRLPLHLY*

CYP?        Oryza sativa (rice)
            GeNEMBL AU064265
            Yamamoto,K. and Sasaki,T.
            Rice cDNA from panicle (longer than 10cm)
            Unpublished (1997)
            This fragment is 45% identical to CYP84A1, but it is too short to name.
            same sequence as C73739

WIFVVVSWKKLNCMRRRLPPGPPRWPIFGNLLQLSPLPHKDFARFCIKYG
PLVYLRLGTIDAITTDDPEVIREILIRQDEVFASRPRTLAAVHLAYGCGD
VALAPLGPNWKRMRRVCMEHLLTTKRLESFAAXRALEAXQLC

PCR fragments from Catharanthus roseus not assigned to families

            Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69776 (316bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 4 from Fig. 2.
            Possible 71 family member 53% to 71A6
            ACPGVNFAIPIAELALANLIHKFNFSLPDGVTAEDLDPTDVVGFISQKETPLSFIATVA

            Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69777 (319bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 5 from Fig. 2.
            Possible 71D subfamily member 67% to 71D7
            MCPGISFALANVELPLAQLLYHFDWKLPGELKLEELDMEESFGLTVRRKK
            DLLLIPISYACSSVK

            Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69778 (377bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993) 
            Note: sequence 6 from Fig. 2.
            Possible 71D subfamily member 63% to 71D8
            SCPGMLFGIANIELPLALLLYHFNWSLPDGLTSETLDMSETWGITTPRKYDLHLIPTSYYP

            Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69780 (360bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 8 from Fig. 2.
            Possible 71D subfamily member 64% to CYP71D7 89% to X69781
            ICPGISYAIANVQLPLAQLLYHFEWKLPAGMKPEELDMTEILGTAAQRKENLLLIPNSHS
            CSSLKQV

            Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69781 (330bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 9 from Fig. 2.
            Possible 71D subfamily member 66% to 71D10 89% to X69780
            ICPGISYAIANIQLPLRQLLYHFDWKLAGGMKPEELDMAEILGTAAQRKEDLLLIPNSHS
            CSSLKQQV

            Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69782 (331bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 10 from Fig. 2.
            Possible 71D subfamily member 58% to 71D10
            VCPGILFGTTNVELLLAAFLFHFDWELPGGMKPEELDMNELFGAGCIRENPLCLIPSIST
            VVEGN

            Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69783 (350bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 11 from Fig. 2. 47% to 80A1
            ICPGLPMAARVVPLVIASFLHFFSWSFPNGKDAQQLDMNEKLDAA
            LVKEQPLFVIPQPRTTT

            Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69784 (294bp) 76C-like
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 12 from Fig. 2. 53% to 76C2
            ICPGLPLAYRTLHTMLATCIHNFDWKLKDGMKPEDIDIEEKYGL
            TLQLAVPLNVIPVKL

            Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69785 (345bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 13 from Fig. 2.
            Possible 71D SUBfamily member 70% to 71D10
            ICPGMSFAIPNVTLPLAQLLLHFDWKSAVGKLEDLDMTEARV

            Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69786 (301bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 14 from Fig. 2.
            Possible 71 family member 60% TO 71D7
            MCPGISFGIPNIELPLALLLFHFNWNLPAGHVLDMEEAMGLTAT
            RKNHLWLVATPIKKCLNLLSKLHNLDNMFSLDSNKV

            Catharanthus roseus (Madagascar periwinkle) PCR fragment
            GenEMBL X69787 (346bp)
            Meijer,A.H., Souer,E., Verpoorte,R. and Hoge,J.H.C.
            Isolation of cytochrome P-450 cDNA clones from the higher plant
            Catharanthus roseus by a PCR strategy.
            Plant Molec. Biol. 22, 379-383 (1993)
            Note: sequence 15 from Fig. 2. 58% TO 89A SEQUENCES
            ICPGYGLALLHLEYFVANLIWYFEWTAMDGNDIDLSEKQEFTIC
            MKNPLSAYISPRVNTF

Arabidopsis thaliana ESTs (expressed sequence tags) not assigned to families

            Arabidopsis thaliana EST
            GenEMBL  (399bp) T13587
            C-terminal fragment

            Arabidopsis thaliana EST
            GenEMBL T14211 (334bp) T13569 (300bp)
            C-helix region probable but very poor sequence, many unreadable
            bases

            Arabidopsis thaliana EST
            GenEMBL Z26103 (308bp)
            C-terminal fragment overlaps with Z29010 and Z29011 CYP81-like

            Arabidopsis thaliana EST
            GenEMBL Z33952 (357bp)
            I-helix region
            Nearly identical to Z34037 71B-like

            Arabidopsis thaliana EST
            GenEMBL Z34037 (288bp)
            I-helix region 
            Nearly identical to Z33963 71B-like

Unidentified fragments from Zea mays and Brassica campestris

            Zea mays (maize)
            GenEMBL T12664 (195bp)
            Baysdorfer,C.
            The maize cDNA program
            unpublished (1993)
            includes K-helix region

            Zea mays (maize)
            GenEMBL T15323 (363bp)
            includes N-terminal

            Brassica campestris pekinensis (field mustard)
            GenEMBL L33505 (350bp)
            Lim,C.O., Hwang,I. and Cho,M.J.
            Generation of expressed sequence tags from randomly selected flower bud 
            cDNA clones of Brassica campestris ssp. pekinensis by partial sequencing.
            unpublished (1994)