Miscellaneous references on P450s

Last modified: Wed Apr 14 12:57:12 BST 2004

• Andersson, L.A. and Peterson, J.A. (1995) Active-site analysis of ferric P450 enzymes: hydrogen-bonding effects on the circular dichroism spectra. Biochem. Biophys. Res. Commun. 211, 389-395.
• Correia, M.A., Yao, K., Allentoff, A.J., Wrighton, S.A. and Thompson, J.A. (1995) Interactions of peroxyquinols with cytochromes P450 2B1, 3A1, and 3A5: influence of the apoprotein on heterolytic versus homolytic O-O bond cleavage. Arch. Biochem. Biophys. 317, 471-478.
• De Coster, R., Wouters, W. and Bruynseels, J. (1996) P450-dependent enzymes as targets for prostate cancer therapy. J. Steroid Biochem. Mol. Biol. 56, 133-143.
• Di Primo, C., Sligar, S.G., Hui Bon Hoa, G. and Douzou, P. (1992) A critical role of protein-bound water in the catalytic cycle of cytochrome P-450 camphor. FEBS Lett. 312, 252-254.
• Fernandez-Salguero, P.M. and Gonzalez, F.J. (1996) Targeted disruption of specific cytochromes P450 and xenobiotic receptor genes. Methods Enzymol. 272, 412-430.
• Fruetel, J.A., Mackman, R.L., Peterson, J.A. and Ortiz de Montellano, P.R. (1994) Relationship of active site topology to substrate specificity for cytochrome P450terp (CYP108). J. Biol. Chem. 269, 28815-28821.
• Hansch, C. and Zhang, L. (1993) Quantitative structure-activity relationships of cytochrome P-450. Drug Metab. Rev. 25, 1-48.
• Hlavica, P. and Kunzel-Mulas, U. (1993) Metabolic N-oxide formation by rabbit-liver microsomal cytochrome P-4502B4: involvement of superoxide in the NADPH-dependent N-oxygenation of N,N-dimethylaniline. Biochim. Biophys. Acta 1158, 83-90.
• Hoffman, S.M.G., Fernandez-Salguero, P., Gonzalez, F.J. and Mohrenweiser, H.W. (1995) Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19. J. Mol. Evol. 41, 894-900.
• Hodgson, E., Rose, R.L., Goh, D.K., Rock, G.C. and Roe, R.M. (1993) Insect cytochrome P-450: metabolism and resistance to insecticides. Biochem. Soc. Trans. 21, 1060-1065.
• Kukielka, E. and Cederbaum, A.I. (1996) Ferritin stimulation of lipid peroxidation by microsomes after chronic ethanol treatment: role of cytochrome P4502E1. Arch. Biochem. Biophys. 332, 121-127.
• Manchester, J.I., Dinnocenzo, J.P., Higgins, L. and Jones, J.P. (1997) A new mechanistic probe for cytochrome P450: An application of isotope effect profiles. J. Am. Chem. Soc. 119, 5069-5070.
• Mayuzumi, H., Shimizu, T., Sambongi, C., Hiroya, K. and Hatano, M. (1994) Essential role of His163 of cytochrome P450 1A2 in catalytic functions associated with cytochrome b₅. Arch. Biochem. Biophys. 310, 367-372.
• Narasimhulu, S. (1996) Interactions of substrate and product with cytochrome P450 2B4. Biochemistry 35, 1840-1847.
• Nedelcheva, V. and Gut, I. (1995) P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer. Xenobiotica 24, 1151-1175.
• Okazaki, O. and Guengerich, F.P. (1993) Evidence for specific base catalysis in N-dealkylation reactions catalyzed by cytochrome P450 and chloroperoxidase. Differences in rates of deprotonation of aminium radicals as an explanation for high kinetic hydrogen isotope effects observed with peroxidases. J. Biol. Chem. 268, 1546-1552.
• Renaud, J.-P., Davydov, D.R., Heirwegh, K.P.M., Mansuy, D. and Hui Bon Hoa, G. (1996) Thermodynamic studies of substrate binding and spin transitions in human cytochrome P-450 3A4 expressed in yeast microsomes. Biochem. J. 319, 675-681.
• Schlenk, D., Peters, L.D. and Livingstone, D.R. (1996) Correlation of salinity with flavin-containing monooxygenase activity but not cytochrome P450 activity in the euryhaline fish (Platichthys flesus). Biochem. Pharmacol. 52, 815-818.
• Schwarz, D., Krüger, V., Chernogolov, A.A., Usanov, S.A. and Stier, A. (1993) Rotation of cytochrome P450SCC (CYP11A1) in proteoliposomes studied by delayed fluorescence depolarization. Biochem. Biophys. Res. Commun. 195, 889-896.
• Schwarz, D., Richter, W., Krüger, V., Chernogolov, A.A., Usanov, S.A. and Stier, A. (1994) Direct visualization of a cardiolipin-dependent cytochrome P450scc-induced vesicle aggregation. J. Struct. Biol. 113, 207-215.
• Schwarz, D., Kisselev, P., Wessel, R., Jueptner, O. and Schmidt, R.D. (1996) -Branched 1,2-diacyl phosphatidylcholines as effectors of activity of cytochrome P450SCC (CYP11A1): Modeling the structure of the fatty acyl chain region of cardiolipin. J. Biol. Chem. 271, 12840-12846.
• Soucek, P., Martin, M.V., Ueng, Y.-F. and Guengerich, F.P. (1995) Identification of a common cytochrome P450 epitope near the conserved heme-binding petide with antibodies raised against recombinant cytochrome P450 family 2 proteins. Biochemistry 34, 16013-16021.
• Tétreau, C., Di Primo, C., Lange, R., Tourbez, H. and Lavalette, D. (1997) Dynamics of carbon monoxide binding with cytochromes P-450. Biochemistry 36, 10262-10275.
• Wu, D. and Cederbaum, A.I. (1996) Ethanol cytotoxicity to a transfected HepG2 cell line expressing human cytochrome P4502E1. J. Biol. Chem. 271, 23914-23919.
• Yu, X.-C., Shen, S. and Strobel, H.W. (1995) Denaturation of cytochrome P450 2B1 by guanidine hydrochloride and urea: evidence for a metastable intermediate state of the active site. Biochemistry 34, 5511-5517.
• Yu, X.-C., Liang, C. and Strobel, H.W. (1996) Kinetics of substrate reaction in the course of hydroperoxide-mediated inactivation of cytochrome P450 1A1. Biochemistry 35, 6289-6296.
• Yuan, W., White, T.B., White, J.W., Strobel, H.W. and Backes, W.L. (1995) Relationship between hydrocarbon structure and induction of P450: effect on RNA levels. Xenobiotica 25, 9-16.

Back to the Directory of P450-containing Systems home page:

Trieste site

Gödöllõ site