Updated by Kirill Degtyarenko
Last modified: Thu Apr 15 16:56:00 BST 2004
For a list of corresponding EC numbers, click here.
P450 enzymes constitute a superfamily of haem-thiolate proteins, widely distributed in bacteria, fungi, plants and animals. The enzymes are involved in metabolism of a plethora of both exogenous and endogenous compounds. Usually, they act as terminal oxidases in multicomponent electron transfer chains, called here P450-containing monooxygenase systems.
Gene Species PIR SwissProt GenBank/EMBL/DDBJ PRF
CYP51 Sbi P93846 U74319
CYP51 Tae P93596 Y09291
P93595 Y09292
CYP71A1 Pam A35867 P24465 M32885 1608254A
CYP71A2 Sme S36806 P37118 X71654 D14990
CYP71A3 Sme S36807 P37119 X70982 1920266B
CYP71A4 Sme S36805 P37117 X70981 1920266A
CYP71A5 Nra O04163 Y09423
CYP71A6 Nra O04164 Y09424
CYP71A7 Cro Q08568 X69779
CYP71A8 Mpi S45039 Q42716 Z33875
CYP71A? pea Q40985 U29334
CYP71A? Soc P93530 U48434
CYP71A? Soc P93531 U48435
CYP71B1 Tar P49264 L24438 2018333A
CYP71B2 Ath Q41953 Z18072
CYP71B7 Ath Q96514 X97864
CYP71C1 mze Q43254 X81827
Q43250 X81828
CYP71C2 mze Q43255 X81829
O04991 Y11404
CYP71C3 mze Q43256 X81830
P93703 Y11403
CYP71C4 mze Q43257 X81831
O04990 Y11368
CYP71D3 Ath Z27299
CYP72A1 Cro Q05047 L10081 1909351A
CYP72B1 Cro Q42700 L19074
CYP72C1 Cro Q42701 L19075
CYP72 Ath T13009
CYP72? pea Q40986 U29335
CYP73A1 Htu S28495 A47454 Q04468 Z17369
CYP73A2 Pau JC1458 P37115 L07634 1908190A
CYP73A3 Msa S36878 P37114 L11046 1922196A
CYP73A4 Cro P48522 Z32563
Q08577 X69788
CYP73A5 Ath T04086
CYP73A9 pea Q43067 U29243 2209439A
CYP73A10 Pec Q43033 L38898
CYP73A11 Gma Q42797 X92437
CYP73A12 Zel Q43240 U19922
CYP73A14 Gec Q96423 D87520
CYP73A Pki Q40906 D82812 D82813 D82814 D82815
CYP73A Ptr U47293
CYP73A Ath P92993 U71080
CYP73A Ath P92994 U71081 U93215
CYP73A Gec P93146 D89430
CYP73B Pki Q40907 D82813
CYP73C Pki Q40909 D82814
CYP74A1 flx P48417 U00428
CYP74A2 gua Q40778 X78166
CYP74A3 Ath T20864
CYP75A1 Phy S32110 P48418 X71130
S33521 S38985 Z22545
CYP75A2 Sme S43342 P37120 X70824 2006435A
CYP75A3 Phy S33515 S38984 P48419 Z22544
CYP75A4 Gtr Q96581 D85184
CYP75A5 Egr Q96418 U72654
CYP75 Cme D14590
CYP76A1 Sme S38535 P37121 X71658 1924180B
CYP76A2 Sme S38534 P37122 X71657 1924180A
CYP77A1 Sme S40267 P37123 X71656 2005185A
CYP77A2 Sme S40266 S41598 P37124 X71655
CYP78 mze P48420 L23209 T15323 2017366A
CYP79 Sbi Q43135 U32624 2123219A
CYP80 Bst P47195 U09610
CYP82 pea Q43068 U29333 2209439B
CYP83 Ath P48421 U18929 2118365A
CYP84 Ath Q42600 U38416
CYP85 Sly Q43147 U54770
CYP86A1 Ath P48422 X90458
CYP86A2 Ath T04172
CYP86A? Ath O04948 AC000103
CYP88A1 mze Q43246 U32579
CYP89A2 Ath Q42602 U61231
CYP? Ath Z33677 Z33828 Z33963 Z34697
Z35017
CYP? Ath Z35025
CYP? Ath Z33831 Z35218
CYP90 Ath Q42569 X87367 X87368 Z17988 Z26124
CYP90? Ath O04949 AC001229
CYP92A1 mze
CYP92A2 Nta Q43795 X95342
CYP92A3 Nta Q42959 X96784
CYP93A1 Gma Q42798 D83968 2209281A
CYP93A2 Gma Q42799 D86351
CYP97A2 pea Q43078 Z49263
CYP? Nta O04892 D64052
CYP? Gec P93146 D89430
CYP? Gec P93147 D89431
CYP? Gec P93148 D89432
CYP? Gec P93149 D89433
CYP? Gec P93150 D89434
CYP? Gec P93151 D89435
CYP? Gec P93152 D89436
We use combined listing of GenBank, EMBL and DDBJ accession numbers because they use common numbering.
Some sequences can be identified from N-terminal sequences as belonging to a subfamily. These have been included in the listing of the subfamily even though it is premature to assign a specific number to these sequences.
Ath = Arabidopsis thaliana Bst = Berberis stolonifera (barberry) Cme = Campanula medium Cro = Catharanthus roseus (syn. Vinca rosea, Madagascar periwinkle) Egr = Eustoma grandiflorum (lisianthus) flx = flax Gec = Glycyrrhiza echinata Gma = Glycine max (soybean) Gtr = Gentiana triflora gua = guayule (Parthenium argentatum) Htu = Helianthus tuberosus (Jerusalem artichoke) Mpi = Mentha piperita Msa = Medicago sativa (alfalfa) mze = maize (Zea mays) Nra = Nepeta racemosa Nta = Nicotiana tabacum (tobacco) Pam = Persea americana (avocado) Pau = Phaseolus aureus (syn. Vigna radiata, mung bean) pea = garden pea (Pisum sativum) Pec = Petroselinum crispum Phy = Petunia hybrida cv. Blue Star Pki = Populus kitakamiensis Ptr = Populus tremuloides (quaking aspen) Sbi = Sorghum bicolor Sly = Solanum lycopersicum Sme = Solanum melongena cv. Sinsadoharanasu (eggplant) Soc = Solanum chacoense (Chaco potato) Tae = Triticum aestivum (wheat) Tar = Thlaspi arvense Vsa = Vicia sativa Zel = Zinnia elegans
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