Last modified: Thu Apr 15 16:52:37 BST 2004
Updated by Kirill Degtyarenko
Last modified: Thu Apr 15 16:52:37 BST 2004
For a list of corresponding EC numbers, click here.
P450 enzymes constitute a superfamily of haem-thiolate proteins, widely distributed in bacteria, fungi, plants and animals. The enzymes are involved in metabolism of a plethora of both exogenous and endogenous compounds. Usually, they act as terminal oxidases in multicomponent electron transfer chains, called here P450-containing monooxygenase systems.
Gene Species PIR SwissProt GenBank/EMBL/DDBJ PRF
CYP51 Sce A27491 P10614 M15663 M21483 M21484 M18109 1414189A
U04841 T17568 1402214A
2020450JJ
Ctr A26828 A31854 P14263 M17595 M23673 1502218A
1310215A
Cal S02713 P10613 X13296 U67192 U67193 1504336A
Cgl P50859 L40389 S75389
Cgu Q00373 X97680
Cke Q00439 X97682
Cpp Q00585 X97681
Ior Q02315 S75391
Pit S54836 Z49750
Spo Q09736 Z54096
Uma S52319 P49602 Z48164
CYP52A1 Ctr A29297 JS0203 P10615 M15945 M24894 M63258 1507209A
1515252A
1905258A
CYP52A2 Ctr S06148 JT0980 P30607 M63258 X17560 1905258B
1803256A
1515252B
CYP52A3 Cma S08667 JQ1039 P16496 D00481 M27081 X51931 1513184A
JU0095 A33254 P24458 D01168 D12475 1510166A
1801235A
1715132A
CYP52A4 Cma S08668 B40576 P16141 X51932 S64322 D12715 1712155B
Q12581 X55881 1801235B
CYP52A5 Cma A40576 Q12582 X55881 D12714 1712155A
CYP52A6 Ctr S22972 P30608 Z13010 1905258C
CYP52A7 Ctr S22973 P30609 Z13011 1905258D
CYP52A8 Ctr S22974 P30610 Z13012 1905258E
CYP52A9 Cma JS0723 Q12586 D12717
Q12583 D26160
CYP52A10 Cma JS0725 Q12588 D12719
CYP52A11 Cma JS0726 Q12584 D26159
Q12589 D12719
CYP52B1 Ctr S22975 P30611 Z13013 1905258F
CYP52C1 Ctr S22976 P30612 Z13014 1905258G
CYP52C2 Cma JS0724 Q12587 D12718
CYP52D1 Cma JS0722 Q12585 D12716
CYP52E1 Cap P43083 X76225
CYP52E2 Cap Q12573 X87640
CYP53A1 Ani S12015 P17549 X52521
CYP53B1 Rmi Q12668 D63703
CYP54 Ncr S09643 X15033
CYP55A1 Fox A40401 JX0335 P23295 M63340 D14517 1711411A
CYP55A2 Cto Q00616 D78511
CYP55A3 Cto Q12599 D78512
CYP56 Sce B36395 P21595 X55713
CYP57A1 Nha Q12645 L20976
CYP57A2 Nha S34286 P38364 X73145 2019318A
CYP58 Fsp Q12612 U22462 2121428A
CYP59 Eni Q00714 L27825 U34740
CYP60A1 Apa Q12732 L40839 L41149
CYP60A2 Eni Q12609 U34740
CYP60B Eni Q00707 U34740
CYP61 Sce S54015 P54781 U34636 Z49211 2207247A
CYP62 Eni Q12608 U34740
CYP64 Afl U81806 U81807
CYP66 Abi Q92404 Z82021
CYP? Ufa U81793
CYP? Fox X82490
We use combined listing of GenBank, EMBL and DDBJ accession numbers because they use common numbering.
Some sequences can be identified from N-terminal sequences as belonging to a subfamily. These have been included in the listing of the subfamily even though it is premature to assign a specific number to these sequences.
Abi = Agaricus bisporus Afl = Aspergillus flavus Ani = Aspergillus niger Apa = Aspergillus parasiticus Cal = Candida albicans Cap = Candida apicola Cgl = Candida glabrata Cgu = Candida guilliermondii Cke = Candida kefyr Cma = Candida maltosa Cpp = Candida parapsilosis Cto = Cylindrocarpon tonkinense Ctr = Candida tropicalis Eni = Emericella nidulans (syn. Aspergillus nidulans) Fox = Fusarium oxysporum Fsp = Fusarium sporotrichioides Ior = Issatchenkia orientalis Ncr = Neurospora crassa Nha = Nectria haematococca Pit = Penicillium italicum Rmi = Rhodotorula minuta Sce = Saccharomyces cerevisiae (baker's yeast) Spo = Schizosaccharomyces pombe Ufa = Uromyces fabae Uma = Ustilago maydis (smut fungus)
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