Last modified: Thu Apr 15 16:58:10 BST 2004
Updated by Kirill Degtyarenko
Last modified: Thu Apr 15 16:58:10 BST 2004
For a list of corresponding EC numbers, click here.
P450 enzymes constitute a superfamily of haem-thiolate proteins, widely distributed in bacteria, fungi, plants and animals. The enzymes are involved in metabolism of a plethora of both exogenous and endogenous compounds. Usually, they act as terminal oxidases in multicomponent electron transfer chains, called here P450-containing monooxygenase systems.
Gene Species PIR SwissProt GenBank/EMBL/DDBJ PRF
CYP1A1 hum B23585 A24797 P04798 M12079 X04300 X02612 K03191 1210238A
S15803 S16714 D12525 D01198 D10855 D01150
mon S21761 P33616 1814274A
Mir Q29489 D17575
rat A00185 S15584 P00185 K02246 M12170 M14633 M26126 1005262A
M26129 X00469 1010319A
1105202A
1713486A
ham JX0189 Q00557 D10251 D12977 1803390A
gpi F24406 Q06367 D11043 2001208A
rab A27821 B27821 P05176 D00212 M11727 X05685 1109280B
1307202A
Q28716 M19917
cat U82184
dog C37222 1703408B
she S79795
tro P10609 M21310 1410185A
CYP1A1/A3 tro A28789
Cyp1a-1 mou A00184 S15588 P00184 Y00071 M10021 K02588
A23923
Cyp1a-1p mou M11515
CYP1A2 hum S07373 S16718 Q16754 L00383 L00384 L00385 L00386 1210358A
S22433 L00387 L00388 L00389 1918405A
P05177 M12078 M14337 Z00036 M55053
M31664 M31665 M31666 M31667
mon
rat A22562 B24406 P04799 K02422 K03241 M26127 X01031 1009215A
A20963 S16875 1105282A
1005270A
1203207A
ham S13885 JX0190 P24453 M63787 D10252 1803390B
PX0036 1705176C
gpi Q64391 D50457 U23501
rab B27821 P00187 D00213 M11728 X05686 X13853 1008260A
Q29526 M36538 1109280A
1204232A
1307202B
1501250A
dog B37222 1703408C
chi JT0575 Q01741 M64537 1708151A
tro Q92110 S69278
P79830 U62797
Cyp1a-2 mou A00186 B92495 P00186 X00479 M10022 X04283 K02589
A26373 B24953
CYP1A3 tro Q92109 S69277
P79829 U62796
CYP1A4 chi P79760 X99453
CYP1A5 chi P79761 X99454
CYP1A pla S34184 Q92100 X73631
CYP1A Ota Q92095 U14161 2113184A
CYP1A Sch Q92116 U14162 2113184B
CYP1A Chc Q92039 U19855
CYP1A Dla P79716 U78316
CYP1A Mto Q92148 L41886 L41917
CYP1B1 hum Q16678 U03688 2013283A
Q93089 U56438
rat I48130 Q64678 X83867 U09540 2113315A
Cyp1b-1 mou Q64461 X78445 2017226A
Q64429 U03283
Q60593 U02479
CYP2A1 rat A29560 A34272 P11711 J02669 M33312 1604168A
S03981
CYP2A2 rat A31887 S03982 P15149 J04187 M33313 M33325 M34392 1604168B
CYP2A3 rat S15056 A32030 P20812 M33190 J02852 1507164A
S12708
Cyp2a-4 mou A33531 S16067 P15392 M25146 M25147 M26202 M26203 1405272A
S16068 S03979 M26205 M26206 M26207 M26208
J03549 M19319
Cyp2a-5 mou B33531 P20852 M26204 M25205 M25206 M25207
M25208 M25209 M25210 M25211
CYP2A6 hum A00190 S05946 P11509 K03192 M33316 M33318 X06401 1604167A
A34271 B34271 Q16803 X13929 X13897 X13930 1609083A
S04698 1511124A
1509339A
CYP2A6v2 hum Q13120 U22027
CYP2A7 hum C34271 P20853 M33317 1604167B
Q13121 U22029
CYP2A7P hum U22030
CYP2A8 ham S13884 A33293 P24454 M27906 M34446 M34447 M63788 1511056A
PX0037 1705176A
CYP2A9 ham P24455 M34448 M63789 1705176B
CYP2A10 rab Q05555 L10236 1920322A
CYP2A11 rab Q05556 L10237 1920322B
Cyp2a-12 mou S32491 L06463 1912175A
CYP2A13 hum Q16696 U22028
CYP2A bov A35704 P22779
CYP2A mon 1905232B
CYP2B1 rat A00176 S03854 P00176 M11251 L00313 L00314 L00315 0805305A
A22363 S19172 L00316 L00317 L00318 L00319 0904267A
L00320 D00250 M19972 M21412 0904321A
M26854 M26855 M37134 1108237A
J00719 J00720 J00721 J00722
J00723 J00724 J00725 J00726
J00727 J00728
CYP2B2 rat A00177 A21872 P04167 J00720 J00721 J00722 J00723 0907261A
S15589 B00176 J00724 J00725 J00726 J00727 0910215A
S03855 A32736 J00728 K00996 K01626 S51970 1002217A
A21162 K01721 K02427 K02428 M13234
M15947 M19972 M27076
Y00410 M21403 M13650
Q64579 M34452
Q03738 M26853
CYP2B1 or 2B2 A34259
CYP2B3 rat A25459 A29818 P13107 M20406 M19973 U16209 U16210 1407136A
U16211 U16212 U16213 U16214
CYP2B4 rab A00178 A00179 P00178 M20856 M20857 0911310A
B27717 C27717 0905212A
E27717 0901269A
1403250A
1404379A
1919216A
Q29532 S64259
Q29515 L10912
CYP2B5 rab D27717 A27717 P12789 M20855
Q29516 M18820
CYP2B6 hum S04578 A32969 P20813 J02864 M29874 X06399 X06400 1601463A
S07598 S04579 X13494 1515189A
1515189B
Q14096 X16864
CYP2B7P hum Q14097 M29873 J02864
CYP2B8 rat J04808
Cyp2b-9 mou A31047 P12790 M21855
Cyp2b-10 mou B31047 P12791 M21856
Q62397 U48732
+ CPR X99715
CYP2B11 dog S11305 P24460 M33575 M92447 1614241A
CYP2B12 rat S27160 P33272 X63545 S48369 X63545 1901199A
Cyp2b-13 mou K02409
CYP2B14P rat U33540
CYP2B15 rat Q63140 D17343 2004298A
Q62802 D17344
Q64583 D17345 D17346 D17347 D17348
D17349
CYP2B16P rat U33541 U33542 U33543 U33544
U33545 U33546
CYP2B gpi A36154 S15135
CYP2C1 rab A00181 A34257 P00180 K01522 M76597 1002188A
Q00172 M74199
Q29509 D26152
CYP2C2 rab A00182 A27718 P00181 K01521 M14955 M19137 M76596 1002188B
S15587 1403251A
CYP2C3 rab A00183 A22606 Q29525 M31245 M31246 M31247 M31248 1002188C
A34534 M31249 M31250 M31251 M31252 1106190A
M31253 M31254
P00182 K01523 J02901
CYP2C4 rab A26731 B34257 P11371 M74200 M74201 M74202 M74203 1306327A
J02716
CYP2C5 rab A00180 A37828 P00179 J05575 M11299 1111272A
S20227 M74204 M74205 M74206 1614312A
Q29507 M17026
Q29511 M55664
CYP2C6 rat A25954 B25585 P05178 J04466 K03501 M13711 M18336 1209242A
A28516 S00955 Q64614 M24237 M24238 M24239 1302146B
M36848 X06712 M14776
CYP2C7 rat B28516 P05179 M14775 M18774 M31031 M18335 1209242B
1302146A
CYP2C8 hum A29782 S06306 P10632 J03472 M17397 M17398 M21941 1314226A
E28951 C28951 X51535 X54807 M21942 1412182A
S12688 S21423 1412182B
2121231A
Q16743 X65962
CYP2C9 hum A28530 S06863 P11712 J05326 M21940 1819194A
C38462 B38462 M61855 M61857 1313295A
A28951 B28951 L16877 L16878 L16879 L16880 1402324A
L16881 L16882 L16883 1709170A
1501199A
Q16872 S46963
Q16756 D00173
CYP2C10 hum D28951 A27541 P11713 J02832 M15331 M21939 1304180A
CYP2C11 rat A26685 P08683 J02657 X79081 1402198A
M18356 M18357 M18358 M18359 1303289A
M18360 M18361 M18362 M18363
U33173
CYP2C12 rat A32140 P11510 J03786 1409383A
Q64648 M33544 M33545 M33546 M33547 1605163A
M33548 M33549 M33656 M33550
CYP2C13 rat A32470 A36122 P20814 J02861 J05352 M32277 M33994 1511061A
S15586 Q64587 M82846 M82848 M82849 M82850 1604157A
M82851 M82852 M82853 M82854
M82855 M81311 X79810
CYP2C14 rab A26921 P17666 D00190 D00191 1306317A
CYP2C15 rab B27718 P11372 M19234
CYP2C16 rab S12765 A27479 P15123 M18376 M29968 M29661
CYP2C17 hum G38462 P33259 M61858 L07093
CYP2C18 hum D38462 E38462 P33260 M61853 1801333A
Q16751 M61856
Q16703 L16869 L16870 L16871 L16872
L16873 L16874 L16875 L16876
S63421 S63424 S63426 X54808
CYP2C19 hum F38462 P33261 M61854 L31506 L31507
CYP2C20 mon S28166 P33262 S53046 1905232A
CYP2C21 dog A37222 1703408A
CYP2C22 rat A39257 S11160 P19225 M58041 X53477 1703477A
1615337A
CYP2C23 rat S13101 P24470 X55446 1704329A
Q64534 U04733
P97716 S80125
CYP2C24 rat JH0451 P33273 M86677 M86678 1718168A
Q63853 S59652 S59647
Q63854 S59652
Q63855 S59652
CYP2C25 ham Q08078 X63022 2009386A
CYP2C26 ham P33263 D11435
CYP2C27 ham P33264 D11436
CYP2C28 ham P33265 D11437 2112203A
Cyp2c-29 mou Q64458 D17674 2009209A
CYP2C30 rab Q29510 D26153
CYP2C31 got JC2199 Q29478 X76502 2010191A
CYP2C32 pig Q28971 U35733
CYP2C33v1 pig Q28972 U35837 2117161A
CYP2C33v2 pig Q28973 U35838
CYP2C33v3 pig Q28974 U35839
CYP2C34v1 pig Q28975 U35840 2117161B
CYP2C34v2 pig Q28976 U35841
CYP2C34v3 pig Q28977 U35842
CYP2C34v4 pig Q28978 U35843
CYP2C35 pig Q28979 U35844
CYP2C36 pig Q28980 U35845
CYP2C42 pig P79402 Z93098
CYP2C42P1 pig Z93100
CYP2C hum Q16750 X56452
CYP2C pig Q29565 F14781
CYP2C rat B60822
CYP2C dog A60465
CYP2C hor PN0659
Cyp2c mou A23739
CYP2D1 rat A31579 A26822 P10633 J02867 M16654 M22328 1306261A
1414200A
CYP2D2 rat C31579 B26822 P10634 M16655 M22330 X52027 X52455 1306261B
S16871 1414200B
1701403A
CYP2D3 rat E32970 S16872 P12938 J02868 X52028 X52456 1701403B
CYP2D4 rat D31579 S16873 P13108 M22331 X52029 X52457 1414200D
1701403C
CYP2D5 rat B31579 S09611 P12939 J02869 M22329 M25143 X52030 1414200C
S16874 X52458 1701403D
1513478A
CYP2D6 hum A30335 S01199 P10635 M19697 M20403 1506410A
A33629 X07618 X07619 X07620 X08006
X16865 X16866 X16867 Y00300
X90927
Q16752 M33388
Q16804 M24499
Q16753 M33189
CYP2D7P hum M33387 X58467
CYP2D8P hum M33387 X58468
Cyp2d-9 mou A27384 B27384 P11714 M23998 M23997 M24262 M24267 1403249A
S15806 Q64529 U20087 U26265 2116358B
Q64489 M27168 2116358C
Cyp2d-10 mou A30247 S19168 P24456 M24263 1509206A
Q64530 U20088
Q64490 M27167
Cyp2d-11 mou S19169 P24457 M24264
Cyp2d-12 mou
Cyp2d-13 mou
CYP2D14 bov S29295 S37284 Q01361 X68013 S45538 1819257A
Q29454 X68481
CYP2D15 dog D17397 2114248A
CYP2D16 gpi Q64403 U21486 2111231A
CYP2D17 mon Q29488 U38218
CYP2D18 rat Q64680 U48219 U48220 2110198A
CYP2D rat A28702
CYP2E1 hum A31949 P05181 D10014 J02625 J02843 M77918 1301294B
1503130A
Q16868 S77873
mon S28167 P33266 S55205
rat A28145 A25341 P05182 J02627 M20131 S48325 1301294A
S09072 1911515A
1405281A
rab A26579 A27750 P08682 M15061 M18770 M19235 1303357A
1403251C
ham S27176 P51581 D17449 2007232A
pig P79383
Cyp2e-1 mou S18037 S19657 Q05421 X62595 L11650 1919337A
1802364A
1806181A
CYP2E2 rab B27750 B27680 M18771 1407213A
M21351 M21349 M21350 M21358
M21359 M21360 M21361 M21362
M21363
Q29508 M21364 M21365 M21366 M21367
M21368 M21369 M21370 M21371
M21372
CYP2F1 hum A36036 B36036 P24903 J02906 1611209A
1611209B
Cyp2f-2 mou A39302 P33267 M77497 1802218A
CYP2G1 rat A35551 P10610 M31923 M31924 M31925 M31926 1604337A
M31927 M31928 M31929 M31930 1507263A
M31931 M33296 M34444
rab S13907 B31944 P24461 1706166A
CYP2H1 chi A24814 P05180 M13454 1208339A
1507184A
CYP2H2 chi A31418 S10683 P20678 M25469
CYP2J1 rab A40938 P52786 D90405 1717296A
CYP2J2 hum P51589 U37143
CYP2J3 rat P51590 U39943
CYP2J3P1 rat U40000
CYP2J3P2 rat U40004
CYP2J pig P79316 Z84061
CYP2K1 tro S45644 L11528 2015199A
CYP2L1 Paa Q27712 U44826
CYP2M1 tro U16657
CYP2Q Xla D50560
CYP2(EST) Cel M89049
CYP3A1 rat A22631 P04800 M10161 X62086 D13912 1107256A
S39797 D29967 L24207 2002214A
Q64580 X64401
Q64590 M28452
CYP3A2 rat A25222 P05183 M13646 X62087 M74443 1208360A
U09725 U09726 U09727 U09728
U09729 U09730 U09731 U09732
U09733 U09734 X79319 X79320
CYP3A1 or 3A2 B26997 A26997 M86850
C26997
CYP3A3 hum A25170 A29410 P05184 D00003 M13785 X12387 1208395A
2108280A
CYP3A4 hum A25517 A29815 P08684 M14096 M18907 X12387 D11131 1212387A
A32199 S16900 Q16757 J04449 1404264A
S03851
CYP3A5 hum S06491 A34101 P20815 J04813 L35912 1510260A
1602106A
CYP3A5P hum L26985
CYP3A6 rab A29487 A34236 P11707 M19139 U40569 1403281A
Q29506 J05034 1515287A
CYP3A7 hum S04983 S02152 P24462 D00408 1504252A
JX0062
CYP3A8 mon S28168 P33268 S53047 1905232C
S04509 P25231
CYP3A9 rat P51538 U60085
Q64557 U46118
CYP3A10 ham A40843 M73992 S79317
Cyp3a-11 mou S22334 Q64459 X60452 D28565 1813172A
CYP3A12 dog S14275 P24463 X54915 1707145A
Cyp3a-13 mou S18155 Q64464 X63023 2105184A
CYP3A14 gpi Q64417 D16363
Q64407 D49731
CYP3A15 gpi Q64406 D26487
Cyp3a-16 mou Q64481 D26137 2104197A
CYP3A17 gpi Q64409 D28515
CYP3A18 rat S47471 Q64581 X79991 2106148A
CYP3A19 got P79152 X76503
CYP3A23 rat JX0334 Q06884 X96721 2015293A
CYP3A24 she A60728 Q29496 U59378
CYP3A25 mou O09158 Y11995
CYP3A29 pig P79401 Z93099
CYP3A pig Q29598 F14604
CYP3A rat PX0033
CYP3A bab S21176 P80056
CYP3A bov P79102 Y10214
CYP4A1 rat S01336 B32965 P08516 M14972 M33937 M57718 X07259 1516169A
CYP4A2 rat A32965 P20816 M33938 M57719 1516169B
CYP4A3 rat A27700 A32966 P20817 M33936 1516170A
CYP4A2 or 4A3 A26380 S09074
CYP4A4 rab A29368 P10611 J02818 1908184A
Q02927 L04758
CYP4A5 rab A34260 S14761 P14579 M28655 X57209 1709201A
CYP4A6 rab B34260 A34160 P14580 M28656 M29531 L04755 1602211A
CYP4A7 rab C34260 B34160 P14581 J05150 M29530 M28657 1602211B
CYP4A8 rat A36304 P24464 M37828 1701272A
CYP4A9 hum
Cyp4a-10 mou S35608 Q06772 X69296 X71478 2017209A
CYP4A11 hum S29845 S35609 Q02928 L04751 S67580 D26481 1908216A
Q16802 D13705 S67581 2003235A
Q06766 X71480
Cyp4a-12 mou S35610 Q06767 X71479
CYP4A13 gpi S32714 S35611 Q06768 X71481
Cyp4a-14 mou Y11638 Y11639 Y11640 Y11641
Y11642
CYP4A rab PQ0048
CYP4A cat O02845 U91787
Cyp4a mou Y10221 Y10222
CYP4B1 hum S07765 P13584 J02871 X16699 1515193A
1605167A
rat PQ0092 B40164 P15129 M29853 1509332B
rab A40164 P15128 M29852 1509332A
Cyp4b-1 mou D50834 2119162A
CYP4C1 Bld A39381 P29981 M63798 1711468A
CYP4C2 Aal PC2257 Q16903 L38678 2102220A
CYP4C3 Dme Q24121 U34323
CYP4C8 Mda P91762 U77126
CYP4C? Cel Z74043
CYP4D1 Dme S25707 P33269 X67645 1814309A
CYP4D2 Dme S41192 S34291 Q27588 Z23005 2015216A
Q27589 X75955
CYP4D5 Aal PC2270 Q16904 L38679
CYP4D6 Aal PC2271 Q16905 L38680
CYP4D7 Aal PC2272 Q16906 L38681
CYP4D8 Dme Q24127 U34329
CYP4E1 Dme K00045
CYP4E2 Dme Q27606 U56957
Q24291 X86076
Q24130 U34332
CYP4E3 Dme Q24128 U34330
CYP4E4 Dme Q24129 U34331
CYP4F1 rat S29723 P33274 M94548 S53039 1907136A
CYP4F2 hum Q16677 U02388
P78329 D26480
CYP4F3 hum A46661 Q08477 D12620 D12621 S63604 1914182A
CYP4F4 rat P51869 U39206 2205230A
CYP4F5 rat P51870 U39207 2205230B
CYP4F6 rat P51871 U39208 2205230C
CYP4G1 Dme Q24126 U34328
CYP4H1 Aal PC2261 Q16907 L38682
CYP4H2 Aal PC2262 Q16908 L38683
CYP4H3 Aal PC2263 Q16909 L38684
CYP4H4 Aal PC2264 Q16910 L38685
CYP4H5 Aal PC2265 Q16911 L38686
CYP4H6 Aal PC2266 Q16912 L38687
CYP4H7 Aal PC2267 Q16913 L38688
CYP4H8 Aal PC2268 Q16914 L38689
CYP4H9 Aal PC2269 Q16915 L38690
CYP4J1 Aal PC2258 Q16916 L38691
CYP4J2 Aal PC2259 Q16917 L38692
CYP4J3 Aal PC2260 Q16918 L38693
CYP4K1 Aal PC2273 Q16919 L38694
CYP4L1 Mse Q25505 L38668 2119160A
CYP4L2 Mse Q25506 L38669 2119160B
CYP4M1 Mse Q25507 L38670 2119160C
CYP4M2 Mse Q25508 L38671
CYP4M3 Mse Q25509 L38672
CYP4P1 Dme Q24125 U34327
CYP4T1 tro P79835 U82983
CYP4(EST) Cel M89401
CYP4(EST) Cel M80176
CYP5A1 hum A41766 S10750 P24557 M74055 M80646 M80647 S60133 1715147A
Q16844 D34613 D34614 D34615 D34616 1805282A
D34617 D34618 D34619 D34620 1805282B
D34621 D34622 D34623 D34624 2019278A
D34625 S51388 U88978
rat S42404 P49430 D28773 S69335 2007255A
pig P47787 L13128 2008200A
Cyp5a-1 mou JN0683 P36423 L18868 1919229A
U41326 U41327 U41328 U41329
U41330 U41331 U41332 U41333
U41334 U41335 U41336 U41337
U41397
CYP6A1 Mdo A32157 P13527 M25367 1505396A
Q27703 L27241 L27242 2019323A
CYP6A2 Dme A45378 A47198 P33270 M88009 S51248 S81983 1812334A
P91669 U78088
CYP6A3 Mdo Q27691 U09231
CYP6A4 Mdo Q27692 U09232
CYP6A5 Mdo Q27694 U09343
CYP6A6 Mdo Q27695 U09344
CYP6A Dme Q27592 L46858
CYP6A8 Dme Q27593 L46859
CYP6A9 Dme Q27594 L46860
Dgr O01648 U87164
CYP6A? Cca P90730 U78795
CYP6B1v1 Ppx A46367 Q04552 M80828 1902339A
2011165A
CYP6B1v2 Ppx Q04552 M83117 2011165B
CYP6B1v3 Ppx Q27878 Z29624 U05037 2018305A
CYP6B2 Har Q27664 U18085 2202248A
CYP6B3v1 Ppx Q27756 U25819
CYP6B3v2 Ppx Q95038 U65488
CYP6B4v1 Ptg Q27902 U47059
CYP6B4v2 Ptg Q95035 U65489
CYP6B5v1 Ptg Q95036 U65490
CYP6B Har Q95031 U64800
CYP6C1 Mdo Q27693 U09233
CYP6C2 Mdo Q27696 U09345
CYP6D1 Mdo Q27697 U15168 2111312A
Q27698 U22362
Q27699 U22366
Q27700 U22367
CYP7A1 hum S29818 JH0659 P22680 X56088 M89803 M93133 L07951 1908212A
L04629 L04630 L04631 L04632
L04633 L04634 M89647
L20569 L20570
rat A35376 P18125 J05460 J05509 M59184 M59185
M59186 M59187 M59188 M59189
J02926 J05430 X17595 Z14108
Z18860 U01962
rab P51542 L10754 S67315
bov
ham S39399 P46634 L04690
Cyp7a-1 mou A54779 L23754
CYP7B1 rat Q63688 U36992 2205302A
Cyp7b-1 mou Q60991 U36993 2205302B
CYP8 bov JC2350 A53658 Q29626 L34208 D30718 S67757 2017321A
PC2016 2018151A
hum JC2231 Q16647 D38145 S70440 D83402 2012205A
D83393 D83394 D83395 D83396
D83397 D83398 D83399 D83400
D83401 U88977
rat Q62969 U53855
CYP9A1 Hvi U23506
CYP9B1 Dme Q24122 U34324
CYP9B2 Dme Q24123 U34325
CYP9C1 Dme Q24124 U34326
CYP10 Lst JX0225 P48416 S46130 1817288A
CYP11A1 hum A25922 S08081 P05108 D00161 D00162 D00163 D00164 1204185A
S16716 D00165 D00166 D00167 D00168 1305284A
D00169 M14565 M60421 1301351A
X05367 X05368 X05369 X05370
X05371 X05372 X05373 X05374
X58981
Q16805 M28253
Q15081 X14257
rat A27321 A34164 P14137 M63125 M63126 M63127 M63128 1313255A
A23688 M63129 M63130 M63131 M63132 1602215A
M63133 J05156 M22615 1703304A
rab A49189 Q28827 S59219
bov A00189 S04947 P00189 K02130 M25920 M25921 1009264A
1111204A
1207198A
1208259A
Q28152 J05245
pig S03188 PN0018 P10612 X13768
she P79202 D50057 S65754
got P79153 D50058
chi S11144 1616432A
O13254 D49803
tro S32197 Q07217 S57305 1912185A
Dam Q92045 U63299
Cyp11a-1 mou J05511
CYP11B1 hum A34181 S11338 P15538 M24667 X55764 X55765 1602198A
M32863 M32878 M32879 D10169 1614284A
D16153 D16154 D16155
bab Q29527 U52081 U52082 U52083 U52084
U52085
rat B34281 P15393 X15431 S58858 D10107 S63899 1515238A
D14086 D14087 D14088 D14089 1909237A
D14090 D14091 1909237B
1909237C
gpi Q64408 Z69785
bov A28415 B28860 P15150 D00185 D00186 D00361 1311298A
JX0050 JX0071 Q29457 D00449 D00450 D00451 D00452 1508213A
S15805 A38819 D00453 D00454 D00455 D00456 1705242A
D00457 1414286A
M17843 M17844 M36535
ham P97720 S82228
pig Q29552 D38590
she P51663 L34337 L47569 2105192A
Cyp11b-1 mou B41552 P15539 J04451
CYP11B2 hum JX0151 B34181 P19099 X54741 M32864 M32880 M32881 1602198B
A37088 S78399 S78400 D10170 1702153A
Q16726 D13752
rat A35342 B35342 P30099 D00567 S58859 S64136 1918169A
S09736 D14092 D14093 D14094 D14095 1609125A
D14096 D14097
bov
ham Q64658 S73810 U71280
fro Q92104 D10984 2110250A
Cyp11b-2 mou A41552 Q64661 S85260
CYP11B3 rat A34281 S09736 P30100 D14098 D14099 D14100 D14101
B35342 JX0253 D14102 D14103 D00568 X52766
Q64546 U17082 2105269A
U14907 2202323A
CYP11B4 bov cf.CYP11B1, different flanking regions
CYP11B5P bov
CYP11B6P bov
CYP11B7P bov D00458 D00459
CYP11B8P rat D14104 D14105 D14106 D14107
D14108
CYP13A1 Cel Q27520 Z48717
CYP13A2 Cel Q27518 Z48717
CYP13A3 Cel Q27517 Z48717
CYP13A4 Cel Q27513 Z48717
CYP13A5 Cel Q27514 Z48717
CYP13A6 Cel Q27515 Z48717
CYP13A7 Cel Q27519 Z48717
CYP13A8 Cel Q27516 Z48717
CYP13A9P Cel Z48717
CYP13A10 Cel Q09653 Z46934
CYP14A1 Cel Q27506 Z50742
CYP14A2 Cel Q27505 Z50742
CYP14A3 Cel Q27507 Z50742
CYP14A4 Cel Q27510 Z70212
CYP14A? Cel Q27508 Z50742
CYP14A? Cel Q27531 U64847
CYP14? Cel Z83121
CYP14? Cel O02627 U97008
CYP14? Cel O02628 U97008
CYP14? Cel O02651 Z81127
CYP16A1 Cel Q27491 Z54269
CYP17A1 hum A29587 A26366 P05093 M14564 M19489 M63871 1302320A
A40908 A40921 M31146 M31147 M31148 M31149 1313220A
M31150 M31151 M31152 M31153
Z19875 Z20209 S85459 S51705
rat A27659 A30828 P11715 M21208 M22204 M27282 M31681 1502195A
A33980 S16719 X14086 Z11902 S40343 1409199A
1613401A
1816175B
2103157A
ham P70687 U66494
gpi D28860 Q64410 X82878 S75277 2104182A
bov S04346 A26289 P05185 M12547 1203301A
1509192A
hor Q95328 D88184
Q29483 D30688
she Q29497 L40335
tro S21125 P30437 X65800 1809207A
Ola P70085 D87121
P70086 D87122
pig B26366 S22339 P19100 M63507 Z11854 Z11855 Z11856 1809168A
S40340 S40341 S40342 1816175A
U41519 U41520 U41521 U41522
U41523 U41524 U41525
chi JT0318 P12394 M21406 1409257A
Sqa Q92113 S77384 2118305A
Cyp17a-1 mou A39072 P27786 M64863 S41708 1711346A
CYP17A2 bov X59613
CYP18 Dme Q95078 U44753
Q27767 S66112
CYP19 bov P46194 S66248 Z32741 U18447 1924225A
hum S03962 A31255 P11511 J04127 J05105 M28420 S52034 1310327A
A31580 A29480 M30795 M30796 M30797 M30798 1501399A
A23546 A34451 M30799 M30800 M30801 M30802 1507200A
A24344 D24344 M30803 M30804 M74714 X55983 1516307A
B24344 E24344 Y07508 M18856 X13589 S52789 1922320A
C24344 S22908 S52793 S52794 D14473 1922320B
A40142 D29757 D21240 D21241 D13391 1922320C
L21982 S58866 S67203 S67206 1922320D
S67207 S67210 S67214 S85075 1922320E
S96437 S41951 M32245 S71536
Q16731 M22246
Q16449 S85356
rab Q29605 Z68271
Q28684 Z70302
rat A36121 S16901 P22443 M33986 Z11815 S59505
hor Q28373 U37313
pig Q29624 L15471 2122348A
U37309 U37310 U37311 U37312 2122348B
P79286 U52141 2210279A
U57511 U57512 U57513 U57514
U57515 U57516 U57510
P79430 U57517 U57518 U57519 U52142
P79304 U57522 U57520 U57521
O02847 U92245 U92246
chi A31916 P19098 J04047 1414320A
Q03737 M73277 M73278 M73279 M73280
M73281 M73282 M73283 M73284
M73285
M73286 M73287 M73288 M73289
M73290 M73291 M73292 M73293
M73294
M73295 M73296 M73297 M73298
M73299 M73300 M73301 M73302
M73303
jqu Q92150 S46949
P79699 D50336
Pog Q92112 S75898
tro 1806325A
Ipu Q92111 S75715 2017254A
Ola Q92087 D82968 D82969
Tni P70091 U72071
gol P79690 U18974
Cyp19 mou S13912 P28649 D00659 1707124A
CYP19P bov Z32813
CYP21A1 bov A00192 A24101 P00191 K01333 M11267 M12918 M13461 1207187A
A27555 A21181 M13545 1207312A
C28860 1204233A
pig A32525 P15540 M83939 1306214A
she A43349 M92836 M92837 1818301A
Cyp21a-1 mou A00193 A26660 P03940 K03234 M64933 M73820 M15009 1108302A
CYP21A1P hum A21889 A25446 P08686 M12793 M12792 M26857 1513491A
A27865 A32715 M25813 M13936 S38953
Q16746 X58898
Q16747 X58899
Q16874 X58900 X58902 X58901 X58903
Q16748 X58904
X58905 X58906
Q93071 X58907
Q16755 X58908
CYP21A2 hum A00191 P04033 K02771 M25813
Q16806 M17252
Q01204 M26856
X54940 S38953 M19711
X58901 X58902 X58904 X58905
X58906 X58907 X58908
Cyp21a-2p mou K03234 M15008
CYP21A3 pig Q02390 M83939
CYP21B hum Q16741 M31022 M23224 M21544 M21545
M21546 M23225 M21547 M21548
M21549 M21550
Q16742 M28548
CYP22A1 Cel Q27523 U39648
CYP23A1 Cel Q27465 U39472
CYP24 hum A47436 Q07973 L13286 S67623
rat A45228 Q09128 L04608 L04609 L04610 L04611
L04612 L04613 L04614 L04615
L04616 L04617 L04618 L04619
X59506 Z28351 D17792 U03112
Cyp24 mou Q64441 D49438
CYP25A1 Cel Q27476 Z66495
CYP25A2 Cel Q27477 Z66495
CYP25A3 Cel Q27478 Z66495
CYP25A4 Cel Q27479 Z66495
CYP25? Cel Q21262 U50072
CYP27 hum A39740 Q02318 M62401 S62709 X59812
rat A36239 S09198 P17178 M38566 Y07534 1702186A
A33406 U17363 U17369 U17370 U17371
U17372 U17373 U17374 U17375
U17376
rab A30293 A33813 P17177 J04717 1508224A
CYP29A1 Cel Q27480 Z69787
CYP29A2 Cel Z74040
CYP30 Mem
CYP31A1 Cel Q27466 Z68213
CYP31A2 Cel Z68336
CYP32 Cel Q27472 U53148
CYP33A1 Cel Q27470 U55365
CYP33B1 Cel Q27471 U50311
CYP33E1 Cel Q27482 U61945
CYP33E2 Cel Q27499 U61952
CYP33E3P Cel Q20315 U61952
CYP33? Cel O02641 AF003385
CYP35C1 Cel Z77652
CYP35D1 Cel Z83105
CYP36A1 Cel O02645 Z83220
CYP51 hum Q16784 U23942 D55653
Q99868 U51684 U51685 U51686 U51687
U51688 U51689 U51690 U51691
U51692
rat JC2334 Q64654 D55681 U17697
CYP51P1 hum U36926
CYP51P2 hum U40053
CYP51P rat D78370 D87997
Gene Species PIR SwissProt GenBank/EMBL/DDBJ PRF
CYP51 Sce A27491 P10614 M15663 M21483 M21484 M18109 1414189A
U04841 T17568 1402214A
2020450JJ
Ctr A26828 A31854 P14263 M17595 M23673 1502218A
1310215A
Cal S02713 P10613 X13296 U67192 U67193 1504336A
Cgl P50859 L40389 S75389
Cgu Q00373 X97680
Cke Q00439 X97682
Cpp Q00585 X97681
Ior Q02315 S75391
Pit S54836 Z49750
Spo Q09736 Z54096
Uma S52319 P49602 Z48164
CYP52A1 Ctr A29297 JS0203 P10615 M15945 M24894 M63258 1507209A
1515252A
1905258A
CYP52A2 Ctr S06148 JT0980 P30607 M63258 X17560 1905258B
1803256A
1515252B
CYP52A3 Cma S08667 JQ1039 P16496 D00481 M27081 X51931 1513184A
JU0095 A33254 P24458 D01168 D12475 1510166A
1801235A
1715132A
CYP52A4 Cma S08668 B40576 P16141 X51932 S64322 D12715 1712155B
Q12581 X55881 1801235B
CYP52A5 Cma A40576 Q12582 X55881 D12714 1712155A
CYP52A6 Ctr S22972 P30608 Z13010 1905258C
CYP52A7 Ctr S22973 P30609 Z13011 1905258D
CYP52A8 Ctr S22974 P30610 Z13012 1905258E
CYP52A9 Cma JS0723 Q12586 D12717
Q12583 D26160
CYP52A10 Cma JS0725 Q12588 D12719
CYP52A11 Cma JS0726 Q12584 D26159
Q12589 D12719
CYP52B1 Ctr S22975 P30611 Z13013 1905258F
CYP52C1 Ctr S22976 P30612 Z13014 1905258G
CYP52C2 Cma JS0724 Q12587 D12718
CYP52D1 Cma JS0722 Q12585 D12716
CYP52E1 Cap P43083 X76225
CYP52E2 Cap Q12573 X87640
CYP53A1 Ani S12015 P17549 X52521
CYP53B1 Rmi Q12668 D63703
CYP54 Ncr S09643 X15033
CYP55A1 Fox A40401 JX0335 P23295 M63340 D14517 1711411A
CYP55A2 Cto Q00616 D78511
CYP55A3 Cto Q12599 D78512
CYP56 Sce B36395 P21595 X55713
CYP57A1 Nha Q12645 L20976
CYP57A2 Nha S34286 P38364 X73145 2019318A
CYP58 Fsp Q12612 U22462 2121428A
CYP59 Eni Q00714 L27825 U34740
CYP60A1 Apa Q12732 L40839 L41149
CYP60A2 Eni Q12609 U34740
CYP60B Eni Q00707 U34740
CYP61 Sce S54015 P54781 U34636 Z49211 2207247A
CYP62 Eni Q12608 U34740
CYP64 Afl U81806 U81807
CYP66 Abi Q92404 Z82021
CYP? Ufa U81793
CYP? Fox X82490
Gene Species PIR SwissProt GenBank/EMBL/DDBJ PRF
CYP51 Sbi P93846 U74319
CYP51 Tae P93596 Y09291
P93595 Y09292
CYP71A1 Pam A35867 P24465 M32885 1608254A
CYP71A2 Sme S36806 P37118 X71654 D14990
CYP71A3 Sme S36807 P37119 X70982 1920266B
CYP71A4 Sme S36805 P37117 X70981 1920266A
CYP71A5 Nra O04163 Y09423
CYP71A6 Nra O04164 Y09424
CYP71A7 Cro Q08568 X69779
CYP71A8 Mpi S45039 Q42716 Z33875
CYP71A? pea Q40985 U29334
CYP71A? Soc P93530 U48434
CYP71A? Soc P93531 U48435
CYP71B1 Tar P49264 L24438 2018333A
CYP71B2 Ath Q41953 Z18072
CYP71B7 Ath Q96514 X97864
CYP71C1 mze Q43254 X81827
Q43250 X81828
CYP71C2 mze Q43255 X81829
O04991 Y11404
CYP71C3 mze Q43256 X81830
P93703 Y11403
CYP71C4 mze Q43257 X81831
O04990 Y11368
CYP71D3 Ath Z27299
CYP72A1 Cro Q05047 L10081 1909351A
CYP72B1 Cro Q42700 L19074
CYP72C1 Cro Q42701 L19075
CYP72 Ath T13009
CYP72? pea Q40986 U29335
CYP73A1 Htu S28495 A47454 Q04468 Z17369
CYP73A2 Pau JC1458 P37115 L07634 1908190A
CYP73A3 Msa S36878 P37114 L11046 1922196A
CYP73A4 Cro P48522 Z32563
Q08577 X69788
CYP73A5 Ath T04086
CYP73A9 pea Q43067 U29243 2209439A
CYP73A10 Pec Q43033 L38898
CYP73A11 Gma Q42797 X92437
CYP73A12 Zel Q43240 U19922
CYP73A14 Gec Q96423 D87520
CYP73A Pki Q40906 D82812 D82813 D82814 D82815
CYP73A Ptr U47293
CYP73A Ath P92993 U71080
CYP73A Ath P92994 U71081 U93215
CYP73A Gec P93146 D89430
CYP73B Pki Q40907 D82813
CYP73C Pki Q40909 D82814
CYP74A1 flx P48417 U00428
CYP74A2 gua Q40778 X78166
CYP74A3 Ath T20864
CYP75A1 Phy S32110 P48418 X71130
S33521 S38985 Z22545
CYP75A2 Sme S43342 P37120 X70824 2006435A
CYP75A3 Phy S33515 S38984 P48419 Z22544
CYP75A4 Gtr Q96581 D85184
CYP75A5 Egr Q96418 U72654
CYP75 Cme D14590
CYP76A1 Sme S38535 P37121 X71658 1924180B
CYP76A2 Sme S38534 P37122 X71657 1924180A
CYP77A1 Sme S40267 P37123 X71656 2005185A
CYP77A2 Sme S40266 S41598 P37124 X71655
CYP78 mze P48420 L23209 T15323 2017366A
CYP79 Sbi Q43135 U32624 2123219A
CYP80 Bst P47195 U09610
CYP82 pea Q43068 U29333 2209439B
CYP83 Ath P48421 U18929 2118365A
CYP84 Ath Q42600 U38416
CYP85 Sly Q43147 U54770
CYP86A1 Ath P48422 X90458
CYP86A2 Ath T04172
CYP86A? Ath O04948 AC000103
CYP88A1 mze Q43246 U32579
CYP89A2 Ath Q42602 U61231
CYP? Ath Z33677 Z33828 Z33963 Z34697
Z35017
CYP? Ath Z35025
CYP? Ath Z33831 Z35218
CYP90 Ath Q42569 X87367 X87368 Z17988 Z26124
CYP90? Ath O04949 AC001229
CYP92A1 mze
CYP92A2 Nta Q43795 X95342
CYP92A3 Nta Q42959 X96784
CYP93A1 Gma Q42798 D83968 2209281A
CYP93A2 Gma Q42799 D86351
CYP97A2 pea Q43078 Z49263
CYP? Nta O04892 D64052
CYP? Gec P93146 D89430
CYP? Gec P93147 D89431
CYP? Gec P93148 D89432
CYP? Gec P93149 D89433
CYP? Gec P93150 D89434
CYP? Gec P93151 D89435
CYP? Gec P93152 D89436
Gene Species PIR SwissProt GenBank/EMBL/DDBJ PRF
CYP51 Mtu P77901 Z80226
CYP101 Psp A25660 P00183 M12546 D00528 0805198A
1202319A
CYP102 Bme A34286 P14779 J04832 1510269A
CYP102 Bsu O08336 U93874
O08394 D87979
CYP103 Atu A32306 P24466 M19352 1513282A
CYP104 Atu B32306 P24467 M19352 1513282B
CYP105A1 Sgl A35401 P18326 M32238 1613247A
CYP105A2 Aau S47520 Q59079 D26543 2019246A
CYP105B1 Sgl B35401 P18327 M32239 1613247B
CYP105C1 Str S15809 P23296 M31939 1613258A
CYP105D1 Stg S24750 P26911 X63601 S45823 1819469A
CYP105E1 Rfa A55578 P46373 Z29635 2011281A
CYP105? Amo P96562 U84350
CYP106A1 Bme S07764 P14762 X16610 1603257A
CYP106A2 Bme S32215 S39924 Q06069 Z21972 2009359A
CYP107A1 Ser S18531 Q00441 M54983 X60379 1804331B
CYP107B1 Ser B42606 P33271 M83110 1807212B
CYP107C1 Stt Q60005 D30759 M80346 2019205B
CYP107D1 San Q59819 L37200
CYP107E1 Mgr Q59523 D16098 2106351A
CYP107F1 Stg Q59915 D45916 2117310A
CYP107G1 Shy Q54302 X86780
CYP107H1 Bsu P53554 U51868
CYP108 Pse A42971 S27653 P33006 M91440 1817293A
CYP109 Bsu P27632 M36988 1710173A
CYP110A1 Ana C37842 P29980 M38044 1704222C
CYP110A2 Ava Q59163 U38478
CYP111 Pse A48495 Q59723 L23310 1921246A
CYP112 Bja Q59203 U12678 L02323 L12971
CYP113A1 Ser B40634 P48635 L05776 1907186A
CYP113B1 Sfr Q59910 U08223 2018284A
CYP114 Bja Q59204 U12678 L02323 L12971
CYP115P Bja U12678 L02323 L12971
CYP116 Rho P43492 U17130 2104333G
CYP117 Bja Q59205 U12678
CYP118 Mle L04666
CYP119 Sso Q55080 U51337
CYP120 Syn Q59990 D64003
CYP121 Mtu Q59571 Z77163
CYP122A1 Str P77977 U65940
CYP122A2 Shy Q59921 X86780
CYP123 Mtu P77902 Z80226
CYP124 Mtu Q50696 Z77163
CYP125 Mtu P71856 Z82098
CYP126 Mtu P77903 Z80226
CYP127 Rhi Q53215 Z68203
CYP128 Mtu Q59572 Z77163
CYP129 Str Q59971 U50973
CYP130 Mtu Q11062 Z77137
CYP131A1 Spe Q54823 L47164
CYP131A2 Str Q55218 L35154
CYP132 Mtu P77900 Z80108
CYP? Sca JC4287 Q59831 D30815 2121309A
CYP? Mtu P95099 Z83866
CYP? Mtu P96813 Z92770
CYP? Mtu O08362 Z95150
CYP? Mtu O08447 Z96800
CYP? Mtu O08464 Z97193
CYP? Bsu O08469 Y11043 U93876
Gene Species PIR SwissProt GenBank/EMBL/DDBJ PRF
hum S14367
hum S08282 (2C like or 2A like)
rat S09073
CYP2?P rab M12280 M12281 M12282 M12283
M12284 M12285 M12286 M12287
M12288
pig S11471
pig S15850
Cel M88882
Cel Q09660 U21321
chi S10680
chi S10681 S13263
chi S10682
Dre U68234
We use combined listing of GenBank, EMBL and DDBJ accession numbers because they use common numbering.
Some sequences can be identified from N-terminal sequences as belonging to a subfamily. These have been included in the listing of the subfamily even though it is premature to assign a specific number to these sequences.
Aal = Anopheles albimanus (mosquito) Aau = Amycolata autotrophica Abi = Agaricus bisporus Afl = Aspergillus flavus Amo = Amycolatopsis orientalis Ana = Anabaena species Ani = Aspergillus niger Apa = Aspergillus parasiticus Ath = Arabidopsis thaliana Atu = Agrobacterium tumefaciens Ava = Anabaena variabilis bab = baboon (Papio species) Bja = Bradyrhizobium japonicum Bld = Blaberus discoidalis (cockroach) Bme = Bacillus megaterium bov = bovine Bst = Berberis stolonifera (barberry) Bsu = Bacillus subtilis Cal = Candida albicans Cap = Candida apicola cat = cat (Felis catus) Cca = Ceratitis capitata (Mediterranean fruit fly) Cel = Caenorhabditis elegans (nematode worm) Cgl = Candida glabrata Cgu = Candida guilliermondii Chc = Chaetodon capistratus chi = chicken Cke = Candida kefyr Cma = Candida maltosa Cme = Campanula medium Cpp = Candida parapsilosis Cro = Catharanthus roseus (syn. Vinca rosea, Madagascar periwinkle) Cto = Cylindrocarpon tonkinense Ctr = Candida tropicalis Dam = Dasyatis americana (southern stingray) Dgr = Drosophila grimshawi (Hawaiian picture-winged Drosophila) Dla = Dicentrarchus labrax (European sea bass) Dme = Drosophila melanogaster (fruit fly) dog = dog Dre = Danio rerio (zebrafish) Egr = Eustoma grandiflorum (lisianthus) Eni = Emericella nidulans (syn. Aspergillus nidulans) flx = flax Fox = Fusarium oxysporum fro = bullfrog (Rana catesbeiana) Fsp = Fusarium sporotrichioides Gec = Glycyrrhiza echinata Gma = Glycine max (soybean) gol = goldfish got = goat gpi = guinea pig Gtr = Gentiana triflora gua = guayule (Parthenium argentatum) ham = hamster Har = Helicoverpa armigera hor = horse Htu = Helianthus tuberosus (Jerusalem artichoke) hum = human Hvi = Heliothis virescens Ior = Issatchenkia orientalis Ipu = Ictalurus punctatus (channel catfish) jqu = japanese quail Lst = Lymnaea stagnalis (pond snail) Mda = Mastotermes darwiniensis (Australian termite) Mdo = Musca domestica (house fly) Mem = Mercenaria mercenaria (northern quahog) Mgr = Micromonospora griseorubida Mle = Mycobacterium leprae Mir = Macaca irus (crab-eating monkey) mon = monkey mou = mouse Mpi = Mentha piperita Msa = Medicago sativa (alfalfa) Mse = Manduca sexta (tobacco hornworm) Mto = Microgadus tomcod Mtu = Mycobacterium tuberculosis mze = maize (Zea mays) Ncr = Neurospora crassa Nha = Nectria haematococca Nra = Nepeta racemosa Nta = Nicotiana tabacum (tobacco) Ola = Oryzias latipes (medaka), teleost fish Ota = Opsanus tau (toadfish) Paa = Panulirus argus (spiny lobster) Pam = Persea americana (avocado) Pau = Phaseolus aureus (syn. Vigna radiata, mung bean) pea = garden pea (Pisum sativum) Pec = Petroselinum crispum Phy = Petunia hybrida cv. Blue Star pig = pig Pit = Penicillium italicum Pki = Populus kitakamiensis pla = Pleuronectes platessa (plaice) Pog = Poephila guttata (zebra finch) Ppx = Papilio polyxenes (black swallowtail butterfly) Pse = Pseudomonas species Psp = Pseudomonas putida Ptg = Pterourus glaucus Ptr = Populus tremuloides (quaking aspen) rab = rabbit rat = rat Rcu = Romanomermis culicivorax (nematode) Rfa = Rhodococcus fascians Rhi = Rhizobium species Rho = Rhodococcus species Rmi = Rhodotorula minuta San = Streptomyces antibioticus Sbi = Sorghum bicolor Sca = Streptomyces carbophilus Sce = Saccharomyces cerevisiae (baker's yeast) Sch = Stenotomus chrysops (scup) Ser = Saccharopolyspora erythraea Sfr = Streptomyces fradiae Sgl = Streptomyces griseolus she = sheep Shy = Streptomyces hygroscopicus Sly = Solanum lycopersicum Sme = Solanum melongena cv. Sinsadoharanasu (eggplant) Spe = Streptomyces peucetius Spo = Schizosaccharomyces pombe Soc = Solanum chacoense (Chaco potato) Sqa = Squalus acanthias (spiny dogfish shark) Sso = Sulfolobus solfataricus Stg = Streptomyces griseus Str = Streptomyces species Stt = Streptomyces thermotolerans Syn = Synechocystis sp. Tae = Triticum aestivum (wheat) Tar = Thlaspi arvense Tni = Tilapia nilotica tro = trout Ufa = Uromyces fabae Uma = Ustilago maydis (smut fungus) Vsa = Vicia sativa Xla = Xenopus laevis (african clawed frog) Zel = Zinnia elegans
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