Last modified: Thu Apr 15 16:53:30 BST 2004
Updated by Kirill Degtyarenko
Last modified: Thu Apr 15 16:53:30 BST 2004
For a list of corresponding EC numbers, click here.
P450 enzymes constitute a superfamily of haem-thiolate proteins, widely distributed in bacteria, fungi, plants and animals. The enzymes are involved in metabolism of a plethora of both exogenous and endogenous compounds. Usually, they act as terminal oxidases in multicomponent electron transfer chains, called here P450-containing monooxygenase systems.
Gene Species PIR SwissProt GenBank/EMBL/DDBJ PRF
CYP51 Mtu P77901 Z80226
CYP101 Psp A25660 P00183 M12546 D00528 0805198A
1202319A
CYP102 Bme A34286 P14779 J04832 1510269A
CYP102 Bsu O08336 U93874
O08394 D87979
CYP103 Atu A32306 P24466 M19352 1513282A
CYP104 Atu B32306 P24467 M19352 1513282B
CYP105A1 Sgl A35401 P18326 M32238 1613247A
CYP105A2 Aau S47520 Q59079 D26543 2019246A
CYP105B1 Sgl B35401 P18327 M32239 1613247B
CYP105C1 Str S15809 P23296 M31939 1613258A
CYP105D1 Stg S24750 P26911 X63601 S45823 1819469A
CYP105E1 Rfa A55578 P46373 Z29635 2011281A
CYP105? Amo P96562 U84350
CYP106A1 Bme S07764 P14762 X16610 1603257A
CYP106A2 Bme S32215 S39924 Q06069 Z21972 2009359A
CYP107A1 Ser S18531 Q00441 M54983 X60379 1804331B
CYP107B1 Ser B42606 P33271 M83110 1807212B
CYP107C1 Stt Q60005 D30759 M80346 2019205B
CYP107D1 San Q59819 L37200
CYP107E1 Mgr Q59523 D16098 2106351A
CYP107F1 Stg Q59915 D45916 2117310A
CYP107G1 Shy Q54302 X86780
CYP107H1 Bsu P53554 U51868
CYP108 Pse A42971 S27653 P33006 M91440 1817293A
CYP109 Bsu P27632 M36988 1710173A
CYP110A1 Ana C37842 P29980 M38044 1704222C
CYP110A2 Ava Q59163 U38478
CYP111 Pse A48495 Q59723 L23310 1921246A
CYP112 Bja Q59203 U12678 L02323 L12971
CYP113A1 Ser B40634 P48635 L05776 1907186A
CYP113B1 Sfr Q59910 U08223 2018284A
CYP114 Bja Q59204 U12678 L02323 L12971
CYP115P Bja U12678 L02323 L12971
CYP116 Rho P43492 U17130 2104333G
CYP117 Bja Q59205 U12678
CYP118 Mle L04666
CYP119 Sso Q55080 U51337
CYP120 Syn Q59990 D64003
CYP121 Mtu Q59571 Z77163
CYP122A1 Str P77977 U65940
CYP122A2 Shy Q59921 X86780
CYP123 Mtu P77902 Z80226
CYP124 Mtu Q50696 Z77163
CYP125 Mtu P71856 Z82098
CYP126 Mtu P77903 Z80226
CYP127 Rhi Q53215 Z68203
CYP128 Mtu Q59572 Z77163
CYP129 Str Q59971 U50973
CYP130 Mtu Q11062 Z77137
CYP131A1 Spe Q54823 L47164
CYP131A2 Str Q55218 L35154
CYP132 Mtu P77900 Z80108
CYP? Sca JC4287 Q59831 D30815 2121309A
CYP? Mtu P95099 Z83866
CYP? Mtu P96813 Z92770
CYP? Mtu O08362 Z95150
CYP? Mtu O08447 Z96800
CYP? Mtu O08464 Z97193
CYP? Bsu O08469 Y11043 U93876
We use combined listing of GenBank, EMBL and DDBJ accession numbers because they use common numbering.
Some sequences can be identified from N-terminal sequences as belonging to a subfamily. These have been included in the listing of the subfamily even though it is premature to assign a specific number to these sequences.
Aau = Amycolata autotrophica Amo = Amycolatopsis orientalis Ana = Anabaena species Atu = Agrobacterium tumefaciens Ava = Anabaena variabilis Bja = Bradyrhizobium japonicum Bme = Bacillus megaterium Bsu = Bacillus subtilis Mgr = Micromonospora griseorubida Mle = Mycobacterium leprae Mtu = Mycobacterium tuberculosis Pse = Pseudomonas species Psp = Pseudomonas putida Rfa = Rhodococcus fascians Rhi = Rhizobium species Rho = Rhodococcus species San = Streptomyces antibioticus Sca = Streptomyces carbophilus Ser = Saccharopolyspora erythraea Sfr = Streptomyces fradiae Sgl = Streptomyces griseolus Shy = Streptomyces hygroscopicus Spe = Streptomyces peucetius Sso = Sulfolobus solfataricus Stg = Streptomyces griseus Str = Streptomyces species Stt = Streptomyces thermotolerans Syn = Synechocystis sp.
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