Accession numbers for animal P450 sequences. Family CYP1

Compiled by David R. Nelson [Nelson et al. (1996) Pharmacogenetics 6, 1-42]

Updated by Kirill Degtyarenko

Last modified: Thu Apr 15 16:54:24 BST 2004

For a list of corresponding EC numbers, click here.


Species abbreviations

P450 enzymes constitute a superfamily of haem-thiolate proteins, widely distributed in bacteria, fungi, plants and animals. The enzymes are involved in metabolism of a plethora of both exogenous and endogenous compounds. Usually, they act as terminal oxidases in multicomponent electron transfer chains, called here P450-containing monooxygenase systems.

 Gene   Species      PIR     SwissProt       GenBank/EMBL/DDBJ            PRF   
CYP1A1    hum  B23585  A24797  P04798  M12079  X04300  X02612  K03191  1210238A
               S15803  S16714          D12525  D01198  D10855  D01150 
          mon  S21761          P33616                                  1814274A
          Mir                  Q29489  D17575
          rat  A00185  S15584  P00185  K02246  M12170  M14633  M26126  1005262A
                                       M26129  X00469                  1010319A
          ham  JX0189          Q00557  D10251  D12977                  1803390A
          gpi  F24406          Q06367  D11043                          2001208A
          rab  A27821  B27821  P05176  D00212  M11727  X05685          1109280B
                               Q28716  M19917  
          cat                          U82184
          dog  C37222                                                  1703408B
          she                          S79795
          tro                  P10609  M21310                          1410185A
CYP1A1/A3 tro  A28789
Cyp1a-1   mou  A00184  S15588  P00184  Y00071  M10021  K02588         
Cyp1a-1p  mou                          M11515

CYP1A2    hum  S07373  S16718  Q16754  L00383  L00384  L00385  L00386  1210358A
               S22433                  L00387  L00388  L00389          1918405A
                               P05177  M12078  M14337  Z00036  M55053 
                                       M31664  M31665  M31666  M31667 
          rat  A22562  B24406  P04799  K02422  K03241  M26127  X01031  1009215A
               A20963  S16875                                          1105282A
          ham  S13885  JX0190  P24453  M63787  D10252                  1803390B
               PX0036                                                  1705176C
          gpi                  Q64391  D50457  U23501
          rab  B27821          P00187  D00213  M11728  X05686  X13853  1008260A
                               Q29526  M36538                          1109280A
          dog  B37222                                                  1703408C
          chi  JT0575          Q01741  M64537                          1708151A
          tro                  Q92110  S69278
                               P79830  U62797
Cyp1a-2   mou  A00186  B92495  P00186  X00479  M10022  X04283  K02589         
               A26373  B24953                                         
CYP1A3    tro                  Q92109  S69277
                               P79829  U62796
CYP1A4    chi                  P79760  X99453
CYP1A5    chi                  P79761  X99454

CYP1A     pla  S34184          Q92100  X73631
CYP1A     Ota                  Q92095  U14161                          2113184A
CYP1A     Sch                  Q92116  U14162                          2113184B
CYP1A     Chc                  Q92039  U19855
CYP1A     Dla                  P79716  U78316
CYP1A     Mto                  Q92148  L41886  L41917

CYP1B1    hum                  Q16678  U03688                          2013283A
                               Q93089  U56438
          rat  I48130          Q64678  X83867  U09540                  2113315A
Cyp1b-1   mou                  Q64461  X78445                          2017226A
                               Q64429  U03283
                               Q60593  U02479

We use combined listing of GenBank, EMBL and DDBJ accession numbers because they use common numbering.

Some sequences can be identified from N-terminal sequences as belonging to a subfamily. These have been included in the listing of the subfamily even though it is premature to assign a specific number to these sequences.

Pfam family: PF00067

Species abbreviations

Aal = Anopheles albimanus (mosquito)
bab = baboon (Papio species)
Bld = Blaberus discoidalis (cockroach)
bov = bovine
cat = cat (Felis catus)
Cel = Caenorhabditis elegans (nematode worm)
Chc = Chaetodon capistratus
chi = chicken
Dla = Dicentrarchus labrax (European sea bass)
Dme = Drosophila melanogaster (fruit fly)
dog = dog
fro = bullfrog (Rana catesbeiana)
gol = goldfish
got = goat
gpi = guinea pig
ham = hamster
Har = Helicoverpa armigera
hor = horse
hum = human
Hvi = Heliothis virescens
Ipu = Ictalurus punctatus (channel catfish)
jqu = japanese quail
Lst = Lymnaea stagnalis (pond snail)
Mdo = Musca domestica (house fly)
Mir = Macaca irus (crab-eating monkey)
mon = monkey
mou = mouse
Mse = Manduca sexta (tobacco hornworm)
Mto = Microgadus tomcod
Ota = Opsanus tau (toadfish)
pig = pig
pla = Pleuronectes platessa (plaice)
Ppx = Papilio polyxenes (black swallowtail butterfly)
rab = rabbit
rat = rat
Rcu = Romanomermis culicivorax (nematode)
Sch = Stenotomus chrysops (scup)
she = sheep
tro = trout

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