49 730
2C1  PBc1 -------------------------MDP------------
17a  human----------------------------------------
C21  human----------------------------------------
CYP18 Dros--------MLADSYLIKFVLRQLQVQEDGDAQHLL-----
1A1  P1   ----------------------MLFPISMSATEFL-----
22A1 U3964SSWIKCRDWMAFALSHHIIMGIYLLILRNFLPQVVPDFEW
34A2 Z8111----------------------------------------
34A1 Z8111----------------------------------------
34A3 Z8104----------------------------------------
34A6  B021----------------------------------------
34A5  B021----------------------------------------
34A4  T09H----------------------------------------
34A10 B021----------------------------------------
34A9  B021----------------------------------------
34A7  B021----------------------------------------
34A8  B021----------------------------------------
35A1      ----------------------------------------
35A2      ----------------------------------------
35A3      ----------------------------------------
35A4      ----------------------------------------
35A5      ----------------------------------------
35B1      ----------------------------------------
35B2 F40C5----------------------------------------
35B3 K07C6----------------------------------------
35C1 Z7765----------------------------------------
35D1 Z8310----------------------------------------
14A1 Z5074----------------------------------------
14A2 Z5074----------------------------------------
14A3 Z5074----------------------------------------
14A4 Z7021----------------------------------------
14A5      ----------------------------------------
33C1      ----------------------------------------
33C2      ----------------------------------------
33C3      ----------------------------------------
33C4 M8888----------------------------------------
33C5      ----------------------------------------
33C6      ----------------------------------------
33C7      ----------------------------------------
33C8      ----------------------------------------
33C9      ----------------------------------------
33C11     ----------------------------------------
33A1 U5536----------------------------------------
33B1 U5031----------------------------------------
33E1 U6194----------------------------------------
33E2 U6195----------------------------------------
33D1      ----------------------------------------
33D3 C54E1----------------------------------------
23A1 U3947-------------MPIAYFLPSQVNSGVCCLICRHWYLIG
36A1 Z8322----------------------------------------
---VVV-LGLCLSCLL--L-LSLWK-------------QSYGGGKLPPGPTPF-PILGNI--LQIGIKDI
--MWEL-VALLLLTLA--Y-LFWPK-------------RRCPGAKYPKSLLSL-PLVGSL-PFLPRHGHM
-----M-LLLGLLLL---P-LLAGA------------RLLWNWWKLRSLHLP-PLAPGFL--HLLQPDL-
---MVF-LGLLALVTL--L-QWLVR-------------NYRELRKLPPGPWGL-PVIGYL--LFMG-SEK
---LAS-VIFCLVFWV--I-RASRP-------------QVPKGLKNPPGPWGW-PLIGHM--LTLG-KNP
---QHY-FMRVFIVHI----IYIIIS------------YFIRITRYPPGPPPM-AVFGNS--PFV-NILT
---MFL-ILLFSTILA----IALVH-------------QWRARKQLPRGPYPL-PLIGNL--HQL-FYYC
---MFL-VLLFFTIIS----LALAH-------------QWRARKQLPRGPYPL-PLIGNL--HQL-LYYC
---MIF-VTLVTTILI----YFSCK-------------LWRGRKKNPNGPLPL-PLIGNL--HQL-VYNS
---MIL-ILILSAIVA----IFTVN-------------LWRARQKLPKGPTPL-PLIGNL--HQL-IYNA
---MFL-ILILTSILT----YFSIN-------------LWRGRRRNPKGPLPL-PLIGNL--HQL-IYNS
---MLL-ILLFTTVLA----ILIIH-------------QWIKRRNLPNGPTPI-PIIGNL--HQL-FYLY
---MLI-ILLLVTFFA----VATAY-------------QWRKCQRLPKGPTPL-PLIGNF--HQF-IYYG
---MLF-ILILTATVL----ILTVN-------------IWRAWRKLPNGPLPI-PLIGNF--HQL-FYYA
---MLI-ILILVAIAA----VLTVN-------------LWRARQKLPNGPTPL-PIIGNF--HQL-FYNG
---MLL-ILILLAVAA----VLTAN-------------LWRARQKLPKGPTPL-PLIGNF--HQL-FYLS
---MFL-VLIFLALSC----WLIIR-------------QYQKVSRLPPGPVSF-PIIGNL--PHI-IYYL
---MFF-VLFFSVLLG----YLIVR-------------QYQKVSRLPPGPISL-PLIGNL--PQI-IYYL
---MFF-VLFIAACLS----WLIVR-------------QYQKVSRHPPGPISF-PLIGNL--PQI-CYYL
---MFV-ILFISAILS----WLIVR-------------QYQKVSRLPPGPVSL-PLIGNL--PQI-FYYL
---MFI-LIVSLIL-T----WLIVR-------------QYQKVSRLPPGPVSL-PLIGNL--PQI-VYYL
---MIF-VLLLTTFLA----VLIIR-------------QYQKARKLPPGPVSL-PLIGNI--HQL-VYHI
---MIV-ILLLTTLIA----FLVAR-------------QYQKAKKLPPGPVSL-PLIGNI--PQL-VYYI
---MII-LIFITTLLT----FLIVR-------------QNQLSKKLPPGPIAF-PIIGNI--PQV-AYYV
---MFF-ILLFVSIIS----FLTAR-------------QFLKAKRLPPGPFSL-PLIGNA--HQV-GYQL
---MIL-ILLFLTAIT----VITVR-------------LYRKVLRFPPGPFPL-PLIGNA--HQI-AYQA
--MSVF-ILAFVIFII----FYVFH-------------FYWKVSKYPKGPLPL-PFIGNI--HQF-KLGY
--MSIL-IVAFVS-IT----VYIAY-------------FYWKVSKYPKGPFPL-PFIGNI--LQI-PSEN
--MSVF-IIAFFTFIT----TYVAY-------------FYWKVSKYPKGPLPL-PFFGNL--LQF-PAEN
--MSPLLILAFFVATV----GYLVH-------------FYLKVRKYPKGPFPL-PVIGNL--HQI-PGGN
--MSVF-IVALSVFII----SYVIS-------------FYWKVRKYPKGPFPL-PFFGNL--LQF-PADN
---MII-ILLLTFLTI----YFVYE-------------LYWKRRNFPPGPCPL-PVFGNL--LSI-ANPP
---MLI-ILLLTVLTV----YLVYE-------------LYWKRRNFPPGPCPL-PVFGNL--LSI-ANPP
---MIL-LLVFTAFLA----FLFHE-------------LYWKRRNLPPGPIPL-PYMGNI--LTM-LMNK
---MII-LLVFTAFLA----FLFHE-------------LYWKRRNLPPGPIPL-PFMGNI--LTM-LLNK
---MIL-LLLSAAVCL----FLFHE-------------LYWKRRSLPPGPTPL-PFMGNT--LAM-LLEK
---MII-LLLSAAVCV----FLFHE-------------LFWKRRHLPPGPTPL-PFMGNI--LAV-ILEK
---MIL-LLLFTVLIA----FLFHE-------------MYWKRRNLPPGPIPL-PLIGNL--QSM-LLEK
-MFFIL-VLVLTGISI----YLFHL-------------LYWKRRNLPPGPTPL-PLFGNT--LPT-LFDI
---MVL-NIILVVVVA----FLFHH-------------LYWKRRNFFPGPTPL-PLIGNL--LSL-RNPA
---MIA-FSIFIAIFF----WLAHC-------------FYFKRRNLPPGPTPL-PFLGNS--LSM-IWEN
---MIF-FLLLTAFVL----YLFNE-------------FYWKRRGLPPGPIPL-PIIGNM--IEL-FSYP
---MIL-IFFALCTLF----FLIHQ-------------YLWRRRGLPPGPTPI-PIFGNL--FQLSGSEA
---MIL-LILTSILII----YLFNH-------------FYWKRRKLPPGPIPL-PIIGNL--YLMTEDVK
---MIL-FIVLSIVSI----YLFDL-------------FYWKRRNLPPGPLPL-PLVGNL--HMMSDDVK
---MLL-LLISSLIFL----FFAYH-------------FSWKRRNYPPGPTPL-PLVGNL--LQL-QKFG
---MLL-LLIFSSIFL----YFFYH-------------FHWKRRNLPPGPRPL-PFLGNL--LSL-KTLK
---QAT-YIYFLTCIT--L-YAIYE-------------LNYKRRRLPNGPVPW-LVAGNM--PSF-INVN
--MLFA-QLVILVIIV--M-LFLCR-------------FANKLRGLPPGPTPW-PFIGNT--FQV-PEDR
----SKSFTKLSE--VYG------PVFTVYLGMKPTVVIHGYDAVKEAL-VDLGEEFSG-----------
----HNNFFKLQK--KYG------PIYSVRMGTKTTVIVGHHQLAKEVL-IKKGKDFSG-----------
----PIYLLGLTQ--KFG------PIYRLHLGLQDVVVLNSKRTIEEAM-VKKWADFAG-----------
----HTRFMELAK--QYG------SLFSTRLGSQLTVVMSDYKMIRECF---RREEFTG-----------
----HLALSRMSQ--QYG------DVLQIRIGSTPVVVLSGLDTIRQAL-VRQGDDFKG-----------
---PEQTFLEYRE--IYG------PIFTLHLSQPTIIL-AEYKTIQE-A-LV--KNGQQ-----------
WKNGGLVEGYAEIEKSFG------KVYTVWIGPMPTVFISDYDVAQE-T-HV--KRANV-----------
WKNGGLVEGYAEIQKSFG------KVYTLWIGPLPTVFIADFEVAHE-T-HV--KRAHE-----------
WKTGGIVAGFQVFKKQYG------KFFTLWFGPIPIVFIADYDIAYE-T-HV--KKANI-----------
WKNGGIVQGFNEFKKQYG------NVFTIWMGPIPSVHIADFDVAHE-T-HV--KRANT-----------
WKTGGMVAGFQEFKKHYG------KFFTLWFGPIPIVFIADYDIAYE-T-HV--KRANV-----------
WKHGGAVSAYRQLEQTYG------KVFTVWIGPLPTVYISDYDLAHE-T-HI--KKSNI-----------
IKLGSAVAVYHEFEKTYG------KVFTIWMGPLPSVYISDYDVAHE-S-HI--KRANI-----------
WRFGGIVEGIKEMKKQYG------KVFTLWMGPLPMVNICDYDIAYE-T-HV--KRANI-----------
WKYGGLVAGFDQFRKQYG------KVFTVWMGPIPAVQICDFDVAHE-T-HV--KKAHT-----------
WKTGSLVAAFNELKKQYG------KVFTVWMGPKPSVYICDYDIAHE-T-HV--KRANI-----------
WATGGIVSTLDLFRKKYG------NIFTLWVGPVPHVSICDYETSHE-V-FV--KGANK-----------
WSTGGIVSTLDLFRKRYG------NIFTLWVGPIPHVSIADYETSHE-V-FV--KNAGK-----------
WSTGGIVSALDLLRKKYG------NIFTLWVGPVPYVSIADFETSHE-V-FV--KNGGK-----------
WTTGSIVSTLDLFRKRYG------NIFTLWVGPLPHVSIADYEISHE-V-FV--KNGSK-----------
WTTGGIVSTLDLFRKRYG------NIFTLWVGPVPHVSIADYETSYE-V-FV--KQGNK-----------
WNEKGVVPAFDLFRKKYG------DVFTIWLGPIPHVSICNYETSQE-V-FV--KNGNK-----------
WREKGVVPAFDLFRQIYG------DVFTIWLGPIPHVSICDYDTSQE-V-FV--KNGSR-----------
WKTEGMVPALDLFRKTYG------NVFTIWLGPIPHVSICDYETSQE-V-FV--KNGNK-----------
WRTGGVTNMLNHFRKEYG------DIFTLWLGPIPHVNITNYELSHE-V-FV--KNSTK-----------
WRRGGILPALDYYR-KYG------NAYTLWLGPKASVSITDFETSQE-V-FV--KQGKK-----------
---VQKYFDVLSK--TYG------PCFTIWIPFPAIV-LTDYEHIKD-A-FV--NQGDT-----------
---IQEYLDDLSK--TYG------PCFTLWTPLPAIV-LTDYEHVKE-A-FV--TQGDA-----------
---IHLYFDELSQ--TYG------PCFTLWTPLPAVV-LTDYDHVKE-A-FV--TQGDA-----------
---LEIWFDELAK--IYG------PCYTVWSPLPCVV-LTDFDHIKN-A-FV--TQGEF-----------
---IQEHLDKLSK--TYG------PCFTVWTPLPAVV-LTDYEHIKE-A-FV--TQGDA-----------
--PGYKAFERWTK--KYG------DVYTFWIGNTPHIMINTWDKIKE-T-FI--RDADT-----------
--PGYEAFERWTK--KYG------DIYTFWIGNTPHIMINTWDKIKE-T-YI--RDAET-----------
--PGYECFRNWTK--KYG------DVYTFWMGKTPYVMISSYDLLKD-T-FV--RDGDT-----------
--PGYECFRNCTK--KYG------DVYTFWMGKTPFVMISSYDLLKD-T-FV--RDGDT-----------
--PGYECFRRWTK--QFG------GVYTFWMGNIPYVIIGSYDLLKE-T-FV--RDGDT-----------
--PGYECFRRWTK--QFG------DVYTFWMGNTPYIIIGTYDLLKE-T-YI--RDGDT-----------
--PGYECFRRWNK--QFG------DLYTFWMGNTPYVIVSSYELMKE-T-FI--RDGDT-----------
--PGYKTFGKLKE--QYG------DAYTFWMGKDPYVMICSYDLLKE-T-FI--RDADT-----------
--PGYKAFARWTA--KYG------DIYTFWLGTRPYILVSSYEALKE-T-FI--KDGET-----------
--PGYECFRRWTR--IYG------DVFTFWLG--------------E-T-FI--KDGET-----------
--PPTAAYDAWTK--KFG------KIYTVWMGTDPAVIITGYKELKD-T-FV--NDGHS-----------
--PGISIFQKWKD--QYG------PIFTFYMGIAPFVVLTDYQDIKE-T-VI--KDGDT-----------
--PGYKMYEKLKD--KYG------PVFTFWLANLPMVTVTDWKLIKQ-H-FI--KDGAN-----------
--PGYSLFSNLKE--QYG------HVYTFWMASLPIVHVTDWNLIKQ-H-FI--KDGGN-----------
----YDIFHKWKK--EFG------PVFTFWLGKRPFIFITSYEVMKE-T-FV--KDGDT-----------
--PGYEAFSNWKK--EYG------PIFTFWMGNKPFVIIASYEKMKE-T-FV--KDGDT-----------
--NVDVLFQSWKQ--QYG------GIFTVWIGPIPLVMVSDLPTIKK-Y-FI--QHADS-----------
---IDLIINEFKK--KYG------GIFTLWLPFPTIVI-CDYDMLKR-N-IV--KNGES-----------
-----RIV-FPLTAKINK-------GYGIVFS--NGKRWKETRRFSLMTLRNFGMGK---------RSIE
-----RPQ-MATLDIASNN------RKGIAFA-DSGAHWQLHRRLAMATFALFKDGD---------QKLE
-----RPE-PLTYKLVSKN------YPDLSLG-DYSLLWKAHKKLTRSALLLGIRDS-----------ME
-----RPD-TPFMQTLNG-------GYGIINST--GKLWKDQRRFLHDKLRQFGMTY---------MGNG
-----RPD-LYTFTLISN-------GQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTS--CYLE
-----TSG-RSSAESFVLFTGDRLNGDGVILA--MRQKWKDMRHEISRFMNKWYGAP-----------MD
-----FGT-RYAPGIMNY----VRFDKGVVAS--NGEFWQEHRRFALTTLRNFGFGR-----------NI
-----FGT-RYAPGLMNY----NRYERGVVAS--NGEFFQEHSRFVLSTFRNFASGR-----------NI
-----FGH-RFTTGVMNY----IREGRGIIGS--NGAFWQEHRRFALTTLRNFGLGK-----------NI
-----FGH-RFSNGGMDY----IREGRGIIAS--NGEFWQEHRRFALTTLRNFGLGR-----------NI
-----FGH-RFTIGGMDY----IREGRGIVGS--NGDFWQEHRRFALTTLRNFGVGR-----------NI
-----FGA-RFAVGALNY----IREGRGIVAS--NGEFWQEHRRFALTTLRNFGLGR-----------NL
-----FST-RFAHGTTNY----IREGRGIIAA--NGDFWQDHRRFALTTLRNFGLGR-----------NL
-----FVN-RYIHGATEY----IREGRGIIGS--NGDFWLEHRRFALTTFRNFGIGR-----------NI
-----FGH-RYTFGAMEY----IREGKGIIGS--NGDFWLEHRRFALMTLRNFGLGR-----------NI
-----FGT-RYSVGGMEY----IREGRGIIGS--NGDFWLEHRRFALMTLRNFGVGR-----------TI
-----YAD-IAHAPLFRE----LRRWMGVLVT--NGSHWSTMKRFALHTFRDMGVGK-----------DL
-----YAD-KFHAPVMRD----VRSKIGVLIT--NGDHWQEMRRFSLQAFRNMGVGK-----------DI
-----YAD-KLHAPIMRD----IRSMKGIAFT--NGDHWQEMRRFSLQTFRNMGVGK-----------DI
-----YAD-KFHAPVMQD----IRSIMGIMVT--NGDHWQHMRRFSLQTFRNMGVGK-----------DI
-----LAD-VAHSPVLKE----FSRKVGLIRC--NGEHWQVMRRFALQTFRNMGFGK-----------EP
-----YKD-RFLPPVYLH----VSNNLGLFTA--NGPVCAEMRKFTLLAFRNMGVGR-----------DL
-----LID-RFLPPVFLH----LSNNLGLVSA--NGEVWAEMRRFTLLAFRNIGVGR-----------DS
-----FKD-RLLPPIFIH----VSENLGLLTA--NGDSWAEMRGFTLLAFRNMGVGK-----------DL
-----YAD-KHVSPMIDYV---RKGNGVFFS---NGDKWQELRRFSMLTMRNMGMGR-----------DL
------CY-NRQLAPILE---HVTGGVGLLIA--NGENWAEMRRFTLLTFRQMGVGT-----------NI
-----FTY-RAHRSPETLL--PVHDHTGILAS--DGDHWRLQRRTSLKILRDFGLGR-----------NL
-----FIY-RADRPPETLL--QPHLNTGVLFS--NGDNWRFQRRTALKILRDFGLGR-----------NL
-----FIN-RANRPPETLL--QPHLNTGVLGS--SGDNWRLQRRTALKILRDFGLGR-----------NL
------NN-RAHKPPESLL--HVHDNTGILNS--SGENWQLQRRTSLKILRDFGMGK-----------NL
-----FVN-RAQRLPEILF--QPHPNTGVVFS--SGDNWKIQRRTALKILRDFGLGR-----------NL
-----YTN-KVVLPMVTLS---RGGEYGIIDS--NGAMWREHRRFALSTMRDFGLGK-----------NL
-----YTN-KVRLPALDLF---RGGEYGIIDS--NGATWREHRRFALSTMRDFGLGK-----------NL
-----YKD-KYPQPFNQKI---RGGNYGIVES--NGHLWNTHRRFALTTLRDFGLGK-----------DL
-----YKD-KYPQPLNQKI---RGGNYGIVES--NGHLWSTHRRFALTTLRDFGLGK-----------DL
-----YKD-KYPQPFNEKL---RGGMYGIVES--NGHMWSTHRRFALSTLRDFGLGK-----------DL
-----YKD-KYPHPFNEQL---RGGMYGIVES--NGHLWSTHRKFALSTLRNFGLGK-----------DL
-----YKD-KFPQPFNEKF---RGGIFGIIET--NGHLWNTHRRFALSTLRDFGLGK-----------DL
-----YKD-KDYNPIDEKI---RGGIYGILQT--NGHVWNTHRRFALTTFRDFGLGK-----------DL
-----YAD-KKPMAFQESF---RGGSYGVVET--NGPFWREHRRFAIHQFRDFGLGK-----------DR
-----YQD-KIQFSFTEKF---RGGRFGVIET--TGHMWSTHRRFAISTFRDLGLGK-----------NL
-----YLD-KMIYSKLNTS--LRGGDYGVIDT--NGNTWKEHRKFALHTLRDFGMGK-----------EA
-----YAD-KYLSPEFNKY--FREMQFTKLL---SGDRWKEHRKFAVLQLRELGVGK-----------PL
-----FVG-RPEFPISMEM---RQGPYGIIES--HGDRWIQQRRFALHILRDFGLGK-----------NL
-----FVG-RPEFPMSIEL---RQGPYGIIES--HGDRWVQQRRFALHVLRDFGLGK-----------NL
-----FAD-KQLNQIDKKK---LQRNYGVLDT--NGEMWREHRRFTLSQLRDLGLGK-----------DL
-----YVD-KQLTHTEKER---LGENYGVLDT--NGHMWKEHRRFTLTQLRDLGLGK-----------DL
-----FSN-RWRNFVTDSI---MEGSNGIVQI--DGNKWREQRRFALHTLRDFGVGK-----------PL
-----FSG-RPDTFIMDML---VQGNYGLFFM--ENNWWKAQRRFTTHIFRSLGVGQ-----------AG
DRVQEEARCLVEELRKTNGSPCN---------PTFILGAAPCNVICSVIF-------QNRF--DYTDQDF
KIICQEISTLCDMLATHNGQSID---------ISFPVFVAVTNVISLICF-------NTSY--KNGDPEL
PVVEQLTQEFCERMRAQPGTPVA---------IEEEFSLLTCSIICYLTF-------GDKI---KDDNLM
KQQMQKRIMTEVHEFIGHLHASDGQ----PVDMSPVISVAVSNVICSLMM-------STRF--SIDDPKF
EHVSKEAEVLISTLQELMAGPGHFN-------PYRYVVVSVTNVICAICF-------GRRY--DHNHQEL
ELVLHHTRCLEQELAKI-AETKSL------IDLRDPLAGAIANVIQQITI-------GRNY--MYQDQEF
MEERIMDEYRYRFKDFATTGN-NNMAKSFETCARSFFDLLTGSVINKVLI-------NERF--EQDDADF
MEERIMDEYRYRFEDFASSNGINKERKIFETWARPFFDLLTGSVINKILI-------NERF--EQNDPEF
MEDRIMDEYRYNPRLLK-NSRKNGVIEVN---AATMFDLLVGSIINRMLV-------SKRF--EQGNLEF
MEDKIMEEYRYRFKDFKNTHFKNGGIQVN---ASSCFDLLVGSIINQLLV-------SERF--EQDNKEF
MEDKIMDEYRYRIQDFSKTHGKNGVIEVN---ATTMFDLLVGSIINRMLV-------SERF--EQGDQDF
MEEKIMEEYRYRFAQTGNGNNNKSSIETN---SSMFFDLLIGSIINQLLI-------SERF--EEFEKLK
MEEKIMEEYNYRISDYKRTHLKNGAIEIH---AGTFFDLLVGSIINQLLI-------SERF--EQGDQEF
IEGKIMEEYNYRFEDFHETHFKNGAIQVS---ASMFFDLLVGSIINQLLV-------SERF--EQDDKEF
IEDKIMEEYRYRFEDFKKTNFKDGAIQVN---ASSLFDLLVGSIINQLLV-------SERF--EQDDEEF
MEDKIMDEYRYRFKDFKRTHFKNGAIQVN---ASSIFDLLVGSIINQLLV-------SERF--EQDDQEF
METRIMEELDARCADTD-KSATDGVTVAQ---AGDFFDLTVGSIINSILV-------GKRF--EEHNKDD
METRIMEELDARCSDID-KLATNGVTITH---ASEFFDLTVGSIINSILV-------GKRF--EEDTKHE
METRILEELDARCSDID-KSAKNGVTVAQ---ASEFFDLTVGSVINSILV-------GKRF--EEDTKHV
METKIMQELDARCAEID-TSAMNGVTVTQ---ASEFFELTVGSIINSILV-------GKRF--DATTKHE
MEIKIMEELDARCAEID-QASINGVTVTS---ASEFFDLTVGSIINSMLV-------GTRF--EDHNKQE
MEQRILDELNTRCAEID-ADAVNGKTIVH---TTEFFDLTVGSVINSLLV-------GKRF--EAEDKDD
MEERILEELDARCEEID-ADAVNGKTVVQ---TSDFFDLAVGSIINNTLI-------GKRF--NAHNKDE
MEKRILDELNARCAEID-ADAVNGKTIVK---ISDFFDLTVGSVINSTLV-------GKRF--EAHNKDE
MEEKILSELDARCAEIN-EKSIDGTTVLQ---VNEFFDLTVGSIINNMLL-------GFRF--DERTKSR
MEKRIMDELNGRCLEIDAQIARNDRAIV----DVKFFDLTVGSVINSFLI-------GKRF--EDEEEFL
MEEQVIRSVHEMLIQLENINDKKNVD------VFWPIQLCVGNVINETLF-------GFHY--KYEDSEK
MEEQVMRSVHEMLAQLERIADKKNVD------MFWPIQLCVGNVINESLF-------SYHY--KYEDSKK
MEEQVMRSVQEMLAQLDHIPDKQNVD------MYWPIQLCVGNVINESLF-------GYHY--KYEDSDK
MEEQIVKSVQEMMTQLEKTDDKKKAD------IFWPVQLCVGNVINQVLF-------GYHF--KYDDCER
MEEQVMRSVHEMLAQLEHISDKKNVD------MYWPIQLCVGNVINESLF-------GYHY--KYEDAGR
MQENILMEVQDVFARLD-AKLGSETD------VPEVFDHAVANVVNQLLF-------GYRF--MG-----
MQENILMEVQDVFARLD-AKLGSETD------IPEVFDHAVANVVNQLLF-------GYRF-VGVGFSKK
MHEKILIEVENIFKKFD-AQLGLEQD------VSVVMNNAIANVINQNIF-------GYRF--EGDKEED
MQEKILIEVEDIFKKFD-AQLGLEQD------VSVVMNNAIANVINQNIF-------GYRF--EGDKEED
MQEKILIEVEDIFRKYD-AQLGKEQD------IQVVLNNAIANVINQTIF-------GYRF--DETNQEE
MQENILIEVEDIFRKFD-AQLGKEQE------IQVVLKNAIANVINQIIF-------GYRF--DATNQDK
MQEKILIEVEDIFRKYD-AQIDKDME------ISTILHNAIANVINQTIF-------GYRF--DESNQEE
MQQKILIEVEDMFRKLD-ENIGEEQD------VPTVLYNAVANVINQIIF-------GYRF--EGVKQEE
MEQRIMLEVEDIFNNCD-KTIGEGVD------LTDIFDRAVGNVINQMLF-------GYRF--DETRADE
MQEKILAEVEAVFQILD-ANLGAEQD------VPEVIYNAVANVINQMIF-------GYRF--DESNQNE
MEASIQLEVDKIDEELK-KVEGKEVN------IQEHFDLAIGNIINQFLF-------GNRF--KDSSKFN
MESKILIEAEELIKKLK-TAEILNED----FLLQSELDVAVGSVINQFLF-------GYRF--DRSKLFE
MEEKVLGEVTAMIDSIR-KSM-EDVD------MQNIFDASVGSVINNMLF-------GYRY--DETNIEE
MEEKVLGEVTAMLDRLR-KTM-DEVD------MQSVFDASVGSVINNLLF-------GYRY--DETNIAE
MQEKVFWVGTCRPTLHC-SIKDLKR-------YFFPDPVLNLSQIFKFQN-------QRDE--FTYLKSL
MQEKILMEVEELFKELD-AHGGEEID------LPKLIDRSVGNVINLTLF-------KRDE--FAHLKSL
MEQMITLEVTSLMNHMEKSCGLDGKE----LHLCPSIAVCVGNIINNMLF-------GLRF--NQDNSYM
TQDTIASLASGLVEKID-GQKDKPIE------LRPLLVHVVGNVIHKHLF-------GFTR--EWNETEI
LSLMGKLNENFK----------ILNSPWVQM-CNNFPILIDY----LPGSH-------------------
NVIQNY-NEGII----------DNLS-KDSL-VDLVPW-LKI----FPNKT-------------------
PAYYKCIQEVLK----------TWSH-WSIQIVDVIPF-LRF----FPNPG-------------------
RRFNFL-IEEGM----------RLFG-EIHT-VDYIPT-MQC----FPSIS-------------------
LSLVNL-NNNFG----------EVVG-SGNP-ADFIPI-LRY----LPNPS-------------------
QTQLRDINAVVK----------EIMTAEVFFVNCYPWL-R------YLPE--------------------
EKLKTNLSRGLE--------------NTGFLDIFCPVN-I------LQSRFLKWRQDSIFQ---------
EKLVSRLAKGFE--------------NTGFLDIFCPVR-I------LESRFLKWRQDTIFE---------
ETMKVYLTKALE--------------EVSIFEAFLPVW-L------LKSNLLRWRTKYT-----------
ERLKTSLAKGLE--------------KVSIFEAFMPVW-V------LKSKLMRWRTKTT-----------
EKLKMYLTKALE--------------ELSIFDSFTPLW-L------LKSRILRWRTKVT-----------
ESL----SIGLE--------------KFGVLDIFLPDW-I------MNAWWMKWRMDDI-----------
EKIKTSLALSLE--------------NFGIIDIFFPTA-I------LDSPLMKWRQKKI-----------
EELKTKLTMALE--------------NSSIIEGVMPLW-L------LKSKFMKWRTKTT-----------
EELKTNLAMALE--------------NGSIIEGVLPLW-M------LKSRFMKWRTKTT-----------
EKLKTSLAEALE--------------NISIIEGFLPLW-V------LKSPLMKWRTKIT-----------
FLKIKEAMGAAF-------------EVFSPFDMAVPVW-F------LRTFFRSRYDMM------------
FLKIKETMDASF-------------ETFSPFDMTAPVW-F------LKTFFKHRYDKI------------
FLRIKNTIDESF-------------KLITPFNTTVPVW-I------LKTFFKDRYDKM------------
FLKIIETMDASI-------------ETASFFDMMVPVW-I------LKTFFKHRYDNL------------
FLDIKNTMEESI-------------GMFSPFDLTMPVW-I------MKSFFRKRYDFL------------
FLEIKRLMAEAA-------------DLFTMFDLVVPVW-F------LKSFFPSRFERV------------
FMKLKKMMDSAS-------------DLFTIFDLTAPVW-M------LKILVPKRCERI------------
FLHLKKIIHVSS-------------DIFTTFDMTVPVW-V------LKTFFPGRFARS------------
FLTMKHMFDEGM-------------DKMTPLFFTLPVW-A------LQKFLAKDFNSI------------
KIKKLFDESSET---------------FNIFDLNVPVW-F------LKTFLPSRFKLT------------
FKTFVKIVDKHL---------RHLQGKMPLLVSAFPWL--------KHVPI-------------------
FETFVKVLDKHL---------KTVQGKTIFLMSAFPWL--------KHFPV-------------------
FETFVKVINKHL---------KIAQGKPQLLVSAFPWL--------RYVPI-------------------
FQKFVSVIDFHL---------RTLLGKCSLLVSAFPML--------RHVPI-------------------
FEKFVKVVDRHL---------KIAQGNASLLVSAFPWL--------RHLPV-------------------
--------PKEN---------EYQELKHIIDSPAEIFG--------KLHIFLAMNIPIFAKLLPES----
KLTISII-PKES---------EYQELKRIIEAPTDLFG--------KPHMFLAMNIPVIAKLMPEF----
FKKLRELMEYQE----------TAFATFKVYVEAFIPK-V------GALLPGRSL---------------
FKKLRELMEYQE----------TAFATFKVYVEAFIPK-V------GALLPGRSL---------------
FERMRHLVEYQE----------KQFATVKVYVEAFVPT-I------GKFLPGKSL---------------
LEKMRYLVEYQE----------KAFTTVKASIQAFAPR-I------GSILPGKSL---------------
YKKLKHLIEFQE----------NVFTSAKVTVQVFAPK-L------GKILPGESL---------------
FTKLKELMEYLE----------TAFATLKIYVEIFVPW-I------GKLLPGKSL---------------
FRTIRAFFNFNS----------GEFASFSMRVQFFLPW-M------GYIMPGPTI---------------
FEKLKDLIDIQE----------KSFASFKLCVQAFVPI-M------NKLLPGKSL---------------
ELKKLLDLFFEV--------QGSLRVYFAYTVDFLPQW-M------VELL--------------------
FTRIKTLVNNFM---------EEVGKPLGVLAFTCHGI-P------SFLVK-------------------
FLELKNRMNKHF---------KLAAEPMGGLIGMNPWL-G------HLPFFKGY----------------
FLDLKEKLNNHF---------QLAAKPIGGLIGMNPWL-G------YFPYFSGYKNGLFYELVFIFKMC-
IDGLRDVASEFR----------------YFIQFLVPWS-S------KIIPGP------------------
IDGMRNVTSQSR----------------YLIQYLVPWT-S------TVLPGP------------------
HRLHQLLDDQSH----------TVMQPIMGAYIAFPVT-S------KIPI--------------------
LDFHVAINDVLE----------HFTSPKTQLLDAWPWL--------AYLDKPL-----------------
---NKILRNNIYIRNYVLEKIKEHQETLDINNPRD---FIDCFLI-KMEQEK--DNQQSE----FTIENL
--LEKLKSHVKIRNDLLNKILENYKEKFRSDSITN---MLDTLMQ-AKMNSDNGNAGPDQDSELLSDNHI
--LRRLKQAIEKRDHIVEMQLRQHKESLVAGQWRD---MMDYMLQ-GVAQPSMEE-GSGQ----LLEGHV
TAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRD---LVDFYLC-EIEKAKAEGTDAELFDGKNHEEQL
--LNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRD---ITDSLIE-HCQEKQLDENANVQ----LSDEKI
--GILRKWTNYKRSGFRLQQWFRTILEEHHVNRHQ-----GDFMSHMIDLQESKQEQ-------FRDLSI
----PLDWILELTKRNIAKRVAQLKSGEHVLHDEP------DDFLDAYLMKMYKDEKEGLDST-FTLDNL
----PFNYILELNKKSIARRVAQLKADEHVLSDDP------DDFLDAYLLKMQKDKNEGLETT-FTLENL
--LAPVEYIYSLVQKEIQERTTSIENGSHVPSEDG------DDFVDAFLIKIEKDKKEGIDST-FTLESL
--FEPFDFIFGLVERGIQKRVSAIKNGTHIPSEEG------EDFVDAFLIKMEKDKNEGIQST-FDLETL
--MAPFDFVYELVKNGIQKRTSEIKNGSHVISEEG------DDFVDAFLIKIEKDKKEGIDST-FTLETL
--LGPFSWIHRLSQRNVQRRMEQIESGEHVIDGDG------TDFMDTYINKIEKDKREGVDST-FT----
--FEPFDFIYEVSKRNLTKRMEAVKSGDHVIEDGG------RDFVDAYILKIQKDENSGAPST-FNLETM
--FAPFDFIYEVGQKGIQRRVAAIENGTHVLSEEG------DDFVDAFIIKIEKDSKEEVEST-FTLETL
--FAPFDFVFEVGKKGIQRRVAAIENGTHTLSEEG------DDFVDAFIVKMEKDKKDGIDSS-FTLETL
--FAPFDFIFELGNRGIQRRVAAIENGTHTLSEEG------DDFVDAFIVKMEKDKKEGIDSS-FTLETL
--MTTQNTAKRFAAAEAVKRIEDIKSGAYEIDESNI-----EDYTDAFLLKIQKDGEDLD----FNIETL
--WSAQETAKNFAAAEAIKRVESIKSGKYVIDENNL-----QDYTDAFLLKIQKEGESKD----FNIETL
--ADAQEIAKNFVAAEALKRFEDIKSGKYVIDENNL-----QDYTDAFLLKMQKEGENLD----FNTETL
--SDAFEVSKAFSAAEAIKRVDQIKSGRYFIDENNL-----QDYTDAFLLKIEKEGQCQD----FNMETL
--VGAQESARVLVASEALKRYDDIKSGKYVIDENNL-----QDYTDAFLLKIVKGEDEKN----FNIQAL
--VAIFEKALNYLSREALARYEKLKTGEYSVNAEDP-----QDFVEAYLAKMEQERLRDSDTP-YTMECL
--LGVQEEILNFVSREANERYEQLKSGEYTVNAENP-----HDFVEAYFAKMEEEKRHGGPTP-YTMKCL
--VEIQEEVLKYVSREASKRYDKMKLGEYTPSSEDP-----QDFVEAFLAKIDQEEQTGGPTH-FTMRCL
--IKDQFEIIDYVSVDAIKRSRDFMNGDYEIDPNNV-----EDIVDAFLLKMKQNPKSDVYES-FSENNL
--WDSRHQIMDHVMKGVEERIRDIESGAYKIDPKKP-----NDVVDAFLSKMKKEEEIAGGQH-YNLKSL
--VGDIGYHNIKNNISSYHTFIEEEVATQVKKYDG-----ESEPENFVHAYMQQMKQTGNPG--LDITNL
--IGELGYHRIKKNIQSYQEFINDEVTSQIKHYDG-----ESEPENFVHAYMQQMKQSGNPN--LDMNNL
--IGELGYHKIQRNIQSYQKFIDEEVVSQIKQYDG-----ESEPENFVHAYLQQMKQSGNPN--LDMNNL
--IGEYGYQRIKRNIKSYQYFIEEEVATQMKSFEE-----ENEPENFVHAYMQQMKQNGHPG--LDVKNL
--IGNLGYHSIKNNIKSYQQFIEEEVTSQLKNYDG-----ESEPENFVHAYMQQMKQTGNPN--LDMTNL
LYEGPIKTFRDTTLAFFNKQIEAHRHRIDFEDLNS----ESTDFVETFLKEQKRRESEGDSETAFSNIQL
MYEGPFKDFRDTAFAFFNKQIEAHRQEVDLNDLNS----ESTDFVETFLKEQKRRESEGDSETNSSNVQL
--DVLLEEWRDNFYSFFDTQIENHRKKIDFDSQES------LDYAEAYLKEQRKQEALGEFEL-FSNKQL
--NELLEEWRDNFYTFFDTQIENHRKKIDFDSQES------LDYAEAYLKEQRKQEALGEFEL-FSNKQL
--DQLLDDWRNSFYTFFDTQIENHRKKIDFDSEES------QDYAEAYLKEQKKQEALGEFEL-FSNTQF
--DQLLNEFKDNFYTFFNAEIENHRRKIDVDSEES------QDYAEAYLKEQRKHEARGEFEL-FSNTQF
--EDLMKDWKNSFYDFFNTQIENHRQKIDFDSEES------QDYAEAYLKEQKKYEALGDTEL-FSNKQL
--DDVLNYWKDTSYEFFNSQIENHRLKIDFDTEES------LDYAEAYLKEQKKQKAQGEFEL-FCDKQL
--LDRFKKYQKGFTEFFGTQIENHKKEIDFELEEN------SDYVEAFLKEQRKREASGDFES-SSTKQL
--EDRIAEKRHDYYNFFYAQIQDHRAKINYQAEEY------LDYAEAYLKEQKNQEQGGLGSDLFSDQQL
--TPDVSRVRDGIYQFFDEQIEEHRQEIDFETSDS------KDYVETFMKEQKKREAEGDFAS-FSNEQL
LMVSGIEEQKRELFRFLRKQIDGAKSQINYEEEHN------EDFVEAYLRKKFQREQKNDFDS-YCDSQL
--KNVIMHNWMGLMEMFRKQATDRLASIDYDSDEY------SDYVEAFLKERKKHENEQDFGG-FRMEQL
--FIVMIQNWMGLVEMFRKQANEKLATIDYESDDY------SDYVEAFLKERKKHENEKDFGG-FEMEQL
TLGDKTKGMKEELDVFFVKQVEEHRKEIDFDTVES------YDYVEAYLKEQKKFRGLLKCFL-FSNKQL
TLSEKVRAKREELDDFFYSQIDEHRNEIDFDNTEN------LDFVEAYLKEQKKREEDGDFSI-SSNKQL
--INGEWNRLMGIKNELLEFLETQIEGHRMNWKDEMI---EQEPEDLTYAYMIEVEKRKRNG--FDDQQL
--SLGIPRTTRANDAIIQNLEQALAKHKTGINYDEE----PSSYMDAFLKEMKIRAAENALEDGFTEKQL
MTTVTDVFGAGTETTSTTLRYGLLLLMKH-PEVIAKVQEEIERVIG----RHR-------SPCMQDRSRM
LTTIGDIFGAGVETTTSVVKWTLAFLLHN-PQVKKKLYEEIDQNVG----FSR-------TPTISDRNRL
HMAAVDLLIGGTETTANTLSWAVVFLLHH-PEIQQRLQEELDHELGPGASSSR-------VP-YKDRARL
VQVIIDLFSAGMETIKTTLLWINVFMLRN-PKEMRRVQDELDQVVG----RHR-------LPTIEDLQYL
INIVLDLFGAGFDTVTTAISWSLMYLVMN-PRVQRKIQEELDTVIG----RSR-------RPRLSDRSHL
ILTCGDMWTGGMETTVTTLRWGIIYLLNN-PEVQAKCQMEILDVFG----NDI--------PDMGKMNQT
AIDMYDLWIAGQETTSTTLAWACACLLNK-PEVVLKAREELVHVTG---GHR--------SLSLTDKKVT
AVDMYDLWLGGQETTSTTLNWACACLLNR-PDVITTAREELIRVTG---GHR--------SLSLIDRRET
AIDLFDLWLAGQDTSSTTLLWAGICLLNH-PEVVEKLRSELLEVTG---GIR--------RLSLTDRART
AVDLYDLWLAGQETTSTTLTWACACLLNY-PEVVKEIRKELTEVTG---GTR--------SLSLTDRPKT
AIDLFDLWLAGQETTSTTLTWAGTCLLNH-PEVVEKLRKELIQITG---GTR--------SVSLTDRAQT
-----DLWIAGQETTSTTLSWACACLLNH-PEVVKIAREELVHLTG---GHR--------SISLTDKTST
IIDVFDLWQAGQETTSTTLTWAFCCLLNH-PNVVKKLRAELMKLTG---GNR--------HVGLNDRADT
AVDLFDLWVAGQETTSTTLCWAFVCLMNY-PEVVEKLRNELTEVTG---GMR--------SVSLADRSST
AVDLFDLWQAGQETTSTTLTWACACLLNH-PEVVEKLRKELTEVTG---GAR--------GVSLTDRTKT
AIDLFDLWQAGQETTSTTLTWACVCLLNH-PEVVEKLRKELTEVTG---GTR--------GVSLTDRTKT
KTMIIDLWMTGQETTTTTLISGFTQLLLH-PEVMVKAREEILKITE--NGSR--------HLSLTDRTST
KTMIIDLWMTGQETTTTTLISGFNQLLLH-PEVMIKAREEILKITE--NGSR--------HLSLTDRTST
KTMLVDLWLTGQETTTTTLTSGFNQLLLH-PEVMVKAREELMNVTE--NGSR--------SLSLTDRSST
KTMIGDLWITGQETTTTTLISGFNQLLLH-PEVMVKAREELMKVTE--NGSR--------SLSLTDRAST
KTMLYDLWLTGQETTTVTLLCGFNHLLAH-PEVMDKAREELLKITE--NRAR--------SLSLSDRPTT
KFVIGDLWLAGQDTTSTTLVAGFNHLVKN-PEIVRKCREEILRITE--NGSR--------PLQLKDRAES
KHVIGDLWLAGQDTTTTTLVSGFNQLVNH-PEVIRKCREEILRITE--NGSR--------PLQLKDRAES
NQVIADLWLAGQDTTATTLVSGFNQLVNN-PEVMRKCREEIMKITE--NGYR--------PLQLKDRAET
KMLITDLWITGQETTTTTLVSAFIQFLNN-PQVMDTVQKELIKVTN--GGSR--------QLSLRDKTET
KLVLHDLWLAGQGTTATTLYVGFMKLVNH-PGIIQNIQKELLDITE--NGAR--------DLTLKDRPNT
CATVLDFWLAGMETTSNSLRWHLAFMMKY-PEVQDKVRKEILDNVG---TAR--------LPSMSDKPNM
CASVLDFWLAGMETTSNSLRWHLAAMMKY-PEIQDKVRKEIFDNVG---TAR--------LPSMSDKPNM
CASVLDFWLAGMETTSNSLRWHLAAMMKY-PEIQDKVRKEIFDNVG---TAR--------LPSMSDKPNM
RACALDFWLAGMETTSNSLRWHIAYMMKH-PDIQDKVRKEILDVVG---NSR--------FPSMSDKPNM
CASVLDFWLAGMETASNSLRWHLAFMMKY-PEVQDKVRNEIFENIG---TAR--------LPSMSDKQNM
LNVCIDLWFAGLNTTTNTITWAISYVLHH-PEVQDKIHEELDKVIG---SDR--------LITTADKNDL
SNVCMDLWFAGLNTTTNTITWAISYILHH-PEVQDKVHEEMDKVIG---SDR--------LITTADKNDL
SNTCLDLWSAGLSTTYTTVTWALAYVLNS-PEVLEKMRSELDEVVG---KDR--------FVTTADKNDL
SNTCLDLWLAGLSTTNTTVNWTICYVLNH-PDVLQKMNEEFDQVVG---SDR--------LVTMGDKNNL
SNTCLDLWLAGVSTTNTTVNWTICYVLNH-PDVLQKMNEEFDQVVG---SDR--------LVTMGDKNNL
ANTCLDLWLAGVSTTNTTVNWTICYVLNH-PEVLQKMNEEFDQVVG---SDR--------LVSMGDKNNL
SNTCLDLWFAGLSTTNTTANWTICYVMNT-PGVLEKIHDELDKVVG---SDR--------LVTTADKNNL
SNNCLDLWTAGLSTTIITINWTICYIMNT-PGVQEKMQEEMDKVVG---GGR--------LVTTADKNDL
SNMCLDLWFAALMTTSNTMTWCFAYTLNY-LDAQQKLHEELDRVIG---SER--------HINTADKPNL
ANMCFDLWFAGLTTTNTTINWTISYVLNH-PEVQDKMQEELDKVVG---SDR--------LVTISDKSSL
KNMCFDMWVAGMHTTTNTMGFLTAFALNN-MDAQRKMQKELTEVIG----DRV--------VTMKDKLNL
ENVCFDIWAAGFDTLTNTVGFLIAYAINY-PEMQMLIHQEIDNYLA---HHSR-------LLTLADKNAL
DSVCFDLWVAGMETTSNTLNWALLYVLLN-PEVRQKVYEELEREIG---SDRI--------ITTTDRPKL
DSVCFDLWVAGMETTSNTLNWALLYVLRN-PEVRQKVYEELDREIG---SDRI--------ITTSDKPKL
YAMCFDLWMAGLQTTTVTLTWGFSFYLHN-ADVQLKIREELDRVIG---NDRL--------ITTADKNCL
CAMLFDLWIAGLMTTTMTMTWGLSYYLYN-PEVQRKIREELDKVIG---NDRL--------ISTADKNDL
KMLLLDLFFAGMETTVTTLKWAFLLMAKN-QKVQKNVQAELDSIGQ----PMI---------EIQHRTRL
IVAIYDLYSAGMETIIIVLRFAFLYLVNN-PETQKRIHEELDRNVG----RER-------QVVMDDQKHL
PYTDATVHEIQRYINLIPNNV--PRATTCNVKFRS--------YLIPKGTAVITSLTSMLYNDKE-FPNP
LLLEATIREVLRLRPVAPMLI--PHKANVDSSIGE--------FAVDKGTEVIINLWALHHNEKE-WHQP
PLLNATIAEVLRLRPVVPLAL--PHRTTRPSSISG--------YDIPEGTVIIPNLQGAHLDETV-WERP
PITESTILESMRRSSIVPLAT--THSPTRDVELNG--------YTIPAGSHVIPLINSVHMDPNL-WEKP
PYMEAFILETFRHSSFVPFTI--PHSTTRDTSLKG--------FYIPKGRCVFVNQWQINHDQKL-WVNP
PYVRATLSEIQRLANVLPWAI--PHKTIEECNIGG--------YDIPVNTEIIPALGAVLFDPNV-FESP
PYLSAVISEVQRVASILNVNL---FRILEEDTYVG-------GQPIRAGTAVTAHISMIHVDETL-FKNH
PYLSAVISEVQRFASILNMNL---FRIIKEDTVVD-------GQPLRAGTAVTAHIAMIHVDEDL-FKNH
PYLMAVLNEIQRIASILNINI---FRELREDTEID-------GQPIAAGTVVANQLSMIHTDEEL-FEDH
PYLGATINEIQRIASILNVNI---FRLMEEDSIIE-------GQPISAGAVLTTQLAMLHTDEKT-FKNH
PYLTAVVNEVQRISSILNVNI---FRQLQEDSHID-------GQPIASGSVVTTQLAMIHTDEDL-FKDH
PYLNAVI-EVQRIASILNVNI---FRQTSEDTTVN-------GQPIAAGTALTTHLSLIHTDENL-FQNH
PYLNAVCNEVQRIASILNINL---FRKIEQDTEIA-------GQPLASGCVVTTQMSMLHTDVEV-YKNP
LYLNATINEIQRIASILNVNL---PRVLEEDALID-------GVLVPAGTAFATQLSAMHTDDET-FKNH
PYLNATINEVQRISSILNVNL---LRILEEDAVID-------GHPVPAGTAFTTQLALLHTDEET-FKNH
PYLNANINEFQRIASILNVNL---FRVLEEDTTID-------SQPVPAGALVTTNLSMLHTDEEI-FKNP
PYLNAMIGEIQRHASILNVSF---WKINKELTYMG-------GHPVDAGALVTAQLSALHVNDTI-FKNP
PYVNAVIGEIQRHASILNVSF---WKINKEFTYMG-------GHPVDAGALVTSQLSALHVNETV-FKNP
PYLNAMIGEIQRHASILNLSF---WKVNKEFTYIG-------GHPVDAGALVTAQLSALHVNETY-FTNP
PYLNAMIGEIQRHASILNVNF---WKINKEFTYMG-------GHPVDAGALVTAQLGTLHVNETV-FENP
PYLNAMIGEIQRHASILNVTF---WKINKELTYMG-------GHPVDSGAVVTAQLGALHVNDTI-FKNP
HYLNATIAEIQRHASILHVNF---WRLVHEPTTVQ-------GHPVDSGSVICAQLGALHVNDDL-FKNP
HYLNATITEIQRHASILNVNF---WRLINEPTNVK-------GYEIDSGTVMTAQLGALHVNNDI-FKNA
HYLNATIAEIQRHASILNVNF---WRLVHEPTIVN-------GYEIDAGAVITSQLGALHVNNDI-FKDP
PYLNATIAEVQRHASILNINF---WRINNEPTVIG-------GHPVDSGCLIASQLSALHTNEKI-FENP
PYLNATIAEIQRHASILNVNF---WRINHETIHFN-------DYQVDPGTMIAAQVGVLHVNEEL-FDNP
PYTQAVIHEVQRCSNMIPFLG---SHQCKEETEIH-------GNRVPAGSLVFAQLWSVMRNDTV-FEDP
PYTQAVIHEVQRCSNMIPILG---THTNRDDILLK-------GKKIPTGTLVFAQIWSVLKNDPV-FEES
PYTQAVIHEVQRFSNMIPILG---THTNKEDILLK-------GKNVPTGTVIFAQIWSVLKNDSV-FEDS
PYTQAVIHEVQRHSNMVPFLG---THSGNKDTNVL-------GQNIPAGTNVLVQAWSVMRNDPI-F---
PYTQAVIHEVQRCSNMVPILA---THMNTEDVLVK-------EHNIPTGTLLFAQIWSVLKNDPV-FEEN
PYFNASINESQRGINILPLNL---QHATTRDTVID-------GFKIPKGTGVVAQISTVMNNEEV-FPDP
PYFNAFIN--------------------------------------------------------------
PYMNAAINEVQRCANLLPVNV---AHATTRDTVIN-------GYAIKKGTGVIAQISTVMLDEKV-FPDP
PYFNAVLNESQRCANIVPINL---FHATTKDTVIN-------GYPVKKGTGVIAQISTVMLDEKV-FPDP
PYFNAVLNESQRCANIVPINL---FHATTKDTVIN-------GYPVKKGTGVIAQISTVMLDEKV-FPEP
PYFNAVLNESQRCANIVTINL---FHATTKDTVIN-------GYPIKKGTGVIAQISTVMLDEKV-FPEP
PYMNAVINESQRCTNIVPINL---FHATTRDTVIN-------GYPVKKGTGVIAQISTVMLDEKV-FPEP
PYMNAVINEAQRCGNIVPLNL---LHCTTKDTVIN-------GYSVKKGTGVVAQISTVMYDEKV-FPDP
PYTNAYINEIQRTANLVPLNL---LHMTTRDTVLK-------GYNIPKGTGVVAQISTVMYDENV-FPEP
PYMNAVINESQRCVNLLPCNL---FHATTRDTVIN-------GNIIPKGTGVIAQISTVMLDEQI-FPDP
PYTNAFINEAQRCANLVPMNL---PHAVTRDVQLL-------GCTIPKGTTVIHQISSVMSDPEI-FEEP
VYFNAFANEAQRVSNILPMNL---PHALTRDVKLK-------GYHLKKGTGVIHQIANVMTDETI-FKDS
NYINATVNESQRLANLLPMNL---SRSTNADVEIA-------GYRIPKDTVITPQISSVMYDPEI-FPEP
NYINATINESQRLANLLPMNL---ARSTTKDVEIA-------GYHIKKNTVIIPQISLVLYNPEI-FPEP
PYLTAFINETQRCANIIPFNL---LHVATRDTVIE-------GYPVKKGTGVIAQIGTVMSDEQI-FPDA
PYLQAFVTETQRTANIIPLNL---IHMTTRDTVID-------GFPIQKGTGVIAQISTVMYDEQV-FPEP
PYVQATINEIQRIANILPINLL--RTVAEDIEID--------GYNFKKGDLIIPQISILMNDPEI-FENP
PYTCAFLQEVYRLGYVLPVNFL--RCTLTDVEDCE-------GYRLNAGTRVIAQFQSVHVDKKH-FPDP
-DRFDPGHFLDASG--------------------KFRKSDYFMPFSTGKRVCVGEALVRMELFLF-LTAI
-DQFMPERFLNPAG------------------TQLISPSVSYLPFGAGPRSCIGEILARQELFLI-MAWL
-HEFWPDRFLEPGK------------------------NSRALAFGCGARVCLGEPLARLELFVV-LTRL
-EEFRPSRFIDTEG--------------------KVRKPEYFIPFGVGRRMCLGDVLARMELFLF-FASF
-SEFLPERFLTPDGAI------------------DKVLSEKVIIFGMGKRKCIGETIARWEVFLF-LAIL
-KQFKPERFLDEEG--------------------KYRVMEEFRPFGLGPRVCLGERIARTELYLI-FASL
-TEFNPERFLE-----------------------VEGLDKKMIPFGIGKRACLGESLAKAELYLV-LGNM
-TEFRPERFLE-----------------------NDDLDKKLIPFGIGRRSCLGESLAKAELYLV-LGNL
-TRFDPERFIE-----------------------NSTLEKKLIPFNLGKRSCPGESLARAELYLI-IGNL
-TEFRPERFLE-----------------------NNNLEKRLIPFGIGKRSCLGESLARAELYLI-TGNM
-TKFDPERFIE-----------------------NNNLDKKLIPFGIGKRSCPGESLARAELYLI-IGNL
-TEFRPERFLE-----------------------NNNLEKKLIPFGIGKRACLGESLARAELYLV-TGNM
-TEFRPERFLE-----------------------NNTLEKKLIPFGIGKRSCPGESLARAELYLI-LSNV
-KEFNPERFME-----------------------NNNLEKKLIPFGIGKRSCPGESLARAELYLI-IANI
-KEFIPERFLE-----------------------NNNLEKRLIPFGIGKRSCPGESLAKAELYLI-IGNL
-QEFRPERFME-----------------------NNNLEKRLIPFGIGKRACPGESLARAELFLI-TGNM
-QEFDPERFIR-----------------------DEELLQKVIPFGVGKRSCIGESLARAELYLV-RHLQ
-QEFNPERFIR-----------------------DGKLLQKVIPFGVGKRNCLGESLAKAELYLV-R---
-QVFEPERYSQ-----------------------DEKLLQKIIPFGVGKRSCLGESLAKAELYLV-RHGT
-LKFDPERYIR-----------------------DENLLQKVIPFGVGKRSCLGESLARAELYLV-NYLL
-REFDPERFIR-----------------------DDTLLQKVIPFGVGKRNCLGESLARSELYLV-GASF
-DKFYPERFIE-----------------------NEQLLSQIIPFGIGKRSCVGENIAKSELYLM-IGNL
-DKFYPERFIE-----------------------NGKLLNQVIPFGIGKRSCVGENLARSELYLL-TGNL
-SKFYPERFIE-----------------------NGKLLNQIIPFGIGKRSCVGENIARSELYLM-IGNL
-EKFNPERFIR-----------------------NENLMQQTIPFGIGKRSCLGESLARAELYLV-KTFF
-KDFNVEKYLK-----------------------NPKLLQQVIPFGIGKRSCVGEQIAKSELYLV-FGNI
-ETFNPSRYLQSDGKTF-----------------DKAVLEKTIPFSIGKRNCVGEGLARMELFLI-FSAL
-SKFNPDRYLMADGKTI-----------------NKSVLERTIPFSVGKRNCVGEGLARMELFLI-FSAL
-HKFNPDRYLLTDGKTF-----------------DKTILERTIPFSVGKRNCVGEGLARMELFLI-FTAL
---FNPDRYLMADGKSF-----------------DKNILEKTIPFSVGKRSCIGEGLARMELFLI-FSAL
-SKFNPDRYLMPDGKTL-----------------NKTVLERTIPFSVGKRNCVGEGLARMELFLI-FSAL
-YTFNPDRFIDENG--------------------KLKKVDELAPFSVGKRSCPGEGLARMELFLF-IANF
----------------------------------------------------------------------
-YKFNPDRFIDEHG--------------------KLIKVEQLIPFSIGRRQCPGEGLARMEIFLC-VANF
-YKFNPDRFIDENG--------------------KPIKIEQLIPFSIGKRQCPGEGLARMEMFLF-LANF
-YKFNPDRFIDENG--------------------KPIKIEQLIPFSIGKRQCPGEGLARMEIFLF-LANF
-YKFNPDRFIGENG--------------------KPIKIEQLIPFSIGKRQCPGEGLARMEIFLL-VANL
-YKFKPERFIDESG--------------------KLIKVDELVPFSIGKRQCPGEGLARMELFLF-IANF
-YTFNPDRFIDDNG--------------------KLVKIEQLIPFSIGKRQCLGEGLARMELFLF-IANF
-YIFKPERFLDDDG--------------------KLKKVEQLVPFSVGKRQCLGEGLARMELFLF-IANF
-YKFQPERFIDENG--------------------ALKKIEQLIPFSVGKRQCLGEGLARMELFLI-VANL
-ERFVPERYLDESG--------------------NLKKIEELVPFSIGKRVCLGEGLARMELFLF-TANS
-QRFDPNRFIDENG--------------------KLKKIEELCPFSMGKRQCIGEGLARMEIFLL-AANL
-YEFKPERFLESDG--------------------SLKKVEELVPFSIGKRQCLGEGLAKMELFLY-FANL
-YEFKPERFLESDG--------------------SLKKVEELVPFSIGKRQCPGEGLAKMELLLF-FANL
-HCFNPGRFIENG---------------------KLKKVDEVIPFSIGKRQCLGEGLARMELFLF-FANI
-YKFKPERFIENG---------------------KFKKVDEVIPFSIGKRQCLGEGLARIELFLF-FANI
-EEFNPSRFLDEDN--------------------NVKKIDEFLPFSIGRRQCLGESLARAELYLV-FANL
-EHFNPDRFLNSRG--------------------EYIRDDRVNPFSMGKRSCLGENLARMEVFLY-FCTL
LQNF-TPKPLVDPKDIDTTPLVSGLGRVPPLYQLSFI-PA*-------------------
LQRF-DLEVPDDGQLPSLEGIPKVVFL-IDSFKVKIK-VRQAWREAQAEGST*-------
LQAF-TLLPSGD-ALPSLQPLPHCSVILKMQPFQVRL-QPRGMGAHSPGQNQ*-------
MHCF-DIALPEGQPLPSLKGNVGATIT-PESFKVCLK--RSPLGPTAADPHHMRNVGAN*
LQRV-EFSVPLG-VKVDMTPIYGLTMKHACCEHFQMQ-LRS*------------------
LQNF-RFYLNRG-DPIPVAERVIGGIK-PYATRVEYLGNRLIN*----------------
LLDY-NLEPVGD-VPKIQTITPFGLLK-RPPPFKVRFVEVEKS*----------------
LLDY-DLEPVGE-IPKLKTLAPFGLLK-QSPEFRIRFVEVEKH*----------------
VLDF-DFEAVGI-KPEIKTSTPFGIMK-RPPNYISD*-----------------------
ILDF-DFESVGA-APRIQTPTPFALMK-RPPSYDIRFIPRSK*-----------------
VLDF-NLEAVGV-KPEIKTSTPFGLMK-RPPNYNIRLIPVSH*-----------------
ILDY-DLQPIGE-VPQIKTTSPCGIMK-RPPVYSLRFVPVHH*-----------------
ILDV-EIEAVGS-IPKILTSNPFGLLR-RPPSYDIRFKPLKV*-----------------
VMEY-EIEPVGA-TPKMKTPTPFSLLK-RPPSYEIRFVKRS*------------------
VIDF-DLKPVGA-IPKIESPTPFSPVK-RPPVYDIRFISRAH*-----------------
ILDY-DLEPVGT-LPKIETTTPFAPMK-RPPVYDIRFVPRSQ*-----------------
---Y-RISNFLF-RLLGTFCSAINSNR-MEHCRQQSCCRIAPEKDHSSWK*---------
FVFY---------RSSVTFSFATNSNN-MANYPLPSLCHTALEKDHSSWK*---------
F------------RSLETSFFAINSSH-MENFRLP-ICHTALGGDHSSWK*---------
VDDE-NF------RSSEISFSAINSSQ-VQNYQPPSLLHTASERDHSSWK*---------
F------------RYLEIYFSDINLSH-MASYQQRRQCRTVLQRERSTWK*---------
ILRYDIKPHGSE-PSTEDKLPYSAGKT-PDKSVKLEFVKL*-------------------
LLRYNIRPHGSL-PSTADQLPYSAGKM-PDKNVHLEFVKL*-------------------
LLRYDIKPHGSL-PSLDDKLPYSVGKM-PDKTVELEFVKL*-------------------
DKLI-SKCIYF--RSLETYYSAIILNL-LGKCHPLEKPFRLALPRDAKPST*--------
LLRYNVKKHGST-PTNEDVYPYSSAKL-PDVSGKLEFVKL*-------------------
IQKY-EFVATSN-IDLTPDWGVVLTAK-PYTCNIIPQF*---------------------
IQKY-EFIPKTN-IDVKPVCGAVLTTK-PYICELVPQAA*--------------------
IQKY-EFIPNGS-IDLSPVPGAVLTTK-PYTCRLIPQSARKFQLF*--------------
IQKY-EFIANGP-VDMSYDFGAVLTIK-PYTCQLKAQF*---------------------
IQKY-EFIPKTN-VDLKPVYGGVITVK-PYLCELVPQNA*--------------------
LNRY-QIHPSKE-GLPSMAKGSGPVVA-PRLFTAILTRRF*-------------------
----------------------------------------*-------------------
FNHY-QISPSSE-GFPSIDKSDRVGVF-PKKFKAILNRRFYGPSKEI*------------
FNRY-KISPSSK-GFPNLDKKDNVGVF-PKDLHAILNKRN*-------------------
FNRY-EISPSSK-VFPNLDKKDNVGVF-PKDLHAILNRRNC*------------------
FNRY-QISPFSE-GFPNLEKNSVVEIF-AKGLRVILTKRHC*------------------
FNRY-QISPSSE-GLPSIDKSERVGVF-PRKFNAILKKRHV*------------------
LNRY-HISPGSS-GLPSLDKSK--GIT-PRKFEPVLSRRHA*------------------
FNRY-RVVPDAN-GPPIIDKAVLGGMH-TKEFKAILQRRHVSE*----------------
FNRY--ITPSSA-GPPSLERTEMVGVF-PRKFQAILTRRY*-------------------
FNRY-EFNCGSN-GVPSLERTFAFIAK-AQDYTCQVKPRYSS*-----------------
FNYF-EFLPASD-GLPSLYKDFSLVSH-VIPYKCRQYIP*--------------------
FNKFDIKFHESN-PNPSIKKEVGVTMK-AKNYRVSMKERY*-------------------
FNRFDIQLHQSN-PNPSVEKEFGVTMK-AKSYRLKLKDRH*-------------------
FNRYDVQLDFSG-NLPDLDKSKDNFVT-PRKFNAVLNKRYV*------------------
FNRYDVMPDFSG-SLPDLDKSKDNFVI-PRKFKAVLKRRYMD*-----------------
IQNF-NFEVAVT-TEVCLKLGNPNFST-RIFKFKIFYSFTRLGTFKKMYFLGYCRRTVG*
MQNF-EWHTDGP-YAPPIDVITSSLRA-PKPFTVRASRR*--------------------