Sept. 22, 1998
Summary of 81 cytochrome P450 genes/pseudogenes in C. elegans Sept. 22, 1998
one of these is a human or mouse contaminant and not of C. elegans origin, so there are 
actually 80 P450 genes in C. elegans.
* indicates duplicated cosmid sequence 

B0213.10    (V) CYP34A5
B0213.11    (V) CYP34A6
B0213.12    (V) CYP34A7
B0213.14    (V) CYP34A8
B0213.15    (V) CYP34A9
B0213.16    (V) CYP34A10
B0304.3     (II) U39472 CYP23A1
B0331       (V) CYP29A4 
C01F6.3     (IV) Z68213 partial missing internal exon CYP31A1P
                     pseudogene missing 25 amino acids at C-helix and in frame stop codon
C03G6.14     (V) 19976(-) starts at 19976 same gene as C13B3.b CYP35A1
C03G6.15     (V) 22385(-)   ends at 20643 same gene as C13B3.a CYP35A2
C06B3.3     (V) Z77652 + T22G5 (continuation) CYP35C1
C12D5.7     (V) U55365 CYP33A1
*C13B3.a    (V) contig 00241 184(+) same gene as C03G6.b CYP35A2
*C13B3.b    (V) contig 00393 1108(+) same gene as C03G6.a CYP35A1
C25E10.2    (V) U50311 CYP33B1
C26F1.2     (V) U53148 CYP32
*C29F7      (X) end of CYP13B1 (formerly 16A1)
C34B7.3     (I) Z83220 36A1
C36A4.1     (III) Z66495 CYP25A1
C36A4.2     (III) Z66495 CYP25A2
C36A4.3     (III) Z66495 CYP25A3
C36A4.6     (III) Z66495 CYP25A4
C41G6.1     (V) Z81047 T13C10 is just upstream see 22685(+) CYP34A3
C44C10.2    (X) Z69787 CYP29A1
C45H4.2     (V) CYP33C1
C45H4.17     (V) not complete CYP33C2 C-terminal not in
                database yet (Sept. 22, 1998)
C49C8.4     (IV) U61945 3' neighbor to F42A9 CYP33E1
C49G7       (V) see 3878(+) very similar to F14H3 CYP35A4
C50H11      (V) 41332(-) CYP33C9
C54E10      (V) 1-2500 (+) partial sequence CYP33D3
                Y80D3 contig 02234 last mod. 3/5/98 and Y69H2, Y17D7A
cm08B12     (V) M89401 CYP4 EST partial CYP42
                Y80D3 contig 01514 last mod. 3/5/98
*cm14F12    (V) M89049 CYP2 EST exact match to F40C5.contig 6 and 
                K07C6.contig 9  CYP35A5
E03E2       (X) see 9157(+) could not identify N-terminal CYP43
F01D5       (II) Z81493 in 4800-5200 region (+) CYP37A1
F02C12.5    (X) Z54269 CYP13B1 partial C29F7 has rest of seq. 
F08F3.7     (V) CYP14A5
F10A3       (V) see 19263-19717(-) same sequence as K05D4 CYP33D1
F11A5       (V) 4622-2500 (-)identical to F10A3 CYP33D1
                cosmid order F14H3, F22B8, F44G3, F10A3, K05D4, F11A5
                in Genbank K05D4 has the sequence 
F14F7.2     (III) Z81503 CYP13A11
F14F7.3     (III) Z81503 CYP13A12
F14H3.a     (V) Z83105 14503(+) only N-terminal present CYP35D2P not annotated
F14H3.10     (V) Z83105 20207(+) CYP35D1
F22B3       (IV) Z68336 partial gene at 5' end continues on upstream
                 cosmid H02I12 CYP31A2 nearly identical to 31A3
F28G4       (V) CYP37B1
********* Please disregard F40C5, it was mismapped or chimeric. Refer to K07C6*****
*F40C5      (V) contig 5 C-terminal fragment similar to C03G6.a
                part of same gene as F40C5 contig 14 CYP35B1
*F40C5      (V) contig 6 9-578(+) identical to K07C6.5 CYP35A5
*F40C5      (V) contig 14 missing N- and C-terminals 
                part of same gene as F40C5 contig 5 K07C6.4 CYP35B1
*F40C5      (V) contig 15 N-terminal up to C-helix
                K07C6.3 CYP35B2
F41B5.5     (V) 474-622(+) 1st exon, 4332(+) 2nd exon a pseudogene 
                these two fragments are split by about 3700bp
                no further exons identified downstream. CYP33C10P
F41B5.4     (V) yk18a10 matches exactly at 6767 CYP33C3
F41B5.3     (V) CYP33C5
F41B5.2     (V) CYP33C7
F41B5.7     (V) CYP33C6
F42A6       (IV) see 8632(-) nearly identical to CYP25A4 on chrIII CYP25A5
F42A9.4     (IV) U61952 pseudogene, missing C-terminal 3' neighbor is 
                 C49C8 CYP33E3P
F42A9.5     (IV) U61952 33E2
F44C8       (V) whole gene of EST CEL10E1 (M88882) 26000-28000(+) 
                nearly identical to F41B5.4 CYP33C4
*H02I12     (IV) end of clone contiues on F22B3   CYP31A2
*K05D4      (V) contig 319 see 4316-4770(-) same as F10A3 CYP33D1
K06B9.1     (IV) U50072 pseudogene, missing C-terminal 25A6P
K06G5       (X) Z81565 see 24404(+) CYP13B2
K07C6.2     (V) CYP35B3
K07C6.3     (V) CYP35B2
K07C6.4     (V) CYP35B1
K07C6.5     (V) CYP35A5
K09A11.2    (X) Z50742 CYP14A1
K09A11.3    (X) Z50742 CYP14A2
K09A11.4    (X) Z50742 CYP14A3
K09A11      (X) Z50742  cosmid end = R04D3.1  Z70212   CYP14A4
K09D9       (V) contig 4 see 4771(-) CYP35A3
*K10D6      (V) Z74040 CYP29A2 continuation of T19B10.1 
*R04D3.1    (X) Z70212 continuation of CYP14A4
R08F11      (V) see 6240-6719(+) CYP33C8
*R10G11     (V) Z83121 see 10487(+) identical to C41G6.1 and T13C10 CYP34A3
T09H2.1     (V) between K07C6 and B0213, has one P450 not on either CYP34A4
T10B9.1     (II) Z48717 CYP13A4
T10B9.2     (II) Z48717 CYP13A5
T10B9.3     (II) Z48717 CYP13A6
T10B9.4     (II) Z48717 CYP13A8 ZK1325 has N-terminal of T10B9.4 
                 Y53C12 has the rest of CYP13A8
T10B9.5     (II) Z48717 CYP13A3
T10B9.6     (II) Z48717 CYP13A9P in region 21668-23536 Probably is a 
                 PSEUDOGENE. One 18bp deletion, one 6bp deletion and one 1bp deletion
                 that causes a frame shift.  6bp deletion eliminates critical Arg 
                 near C-helix.  All three deletions present on two different cosmids.
T10B9.7     (II) Z48717 CYP13A2
T10B9.8     (II) Z48717 CYP13A1
T10B9.10    (II) Z48717 CYP13A7
T10H4.10   (V) z81119 GenBank has two P450s as one gene see 24550(-) 
                and 21093(-) CYP34A1
T10H4.11   (V) z81119 GenBank has two P450s as one gene see 24550(-) 
                and 21093(-) CYP34A2
T13C5.1     (X) U39648 CYP22
*T13C10     (V) Z81591 contig 1348 27256(+)  C41G6 is downstream 
                this gene identical to C41G6.1 and R10G11 CYP34A3
*T13F3      (V) part of F28G4 CYP37B1
T16C6       (IV) contig 00001 see 12708-12920(+) CYP31A3 nearly
                 identical to CYP31A2, but different intron sequences. same as Y17G9
T19B10.1    (V) Z74043 continues on K10D6 (whole gene of wEST00713 
                M80176) CYP29A2
*T22G5      (V) Z81127 C-terminal of C06B3 CYP35C1
*Y17D7A     (V) C54E10 end CYP33D3
*Y17G9      (IV) CYP31A3 and CYP31A4P (P450 fragment inside 31A3 intron)
*Y37D8      (III) F14F7 cluster CYP13A11 and CYP13A12
Y38C9       (V) CYP29A3
*Y38C9B     (V) CYP29A3
*Y39E4      (III) contig 05806 same as CYP13A11 and CYP13A12
*Y39G8      (II) contig 00890 same as CYP37A1 (F01D5)
*Y39H10     (V) CYP33C8
Y49C4           contig 103 CYP33C11
Y53C12      (II) incomplete cosmid sequence covers the whole 13A subfamily 
                 including 13A10, but 13A10 is far from the others, maybe 100kb 5' of 
                 the 13A cluster. fragment order not known (4/14/97)
*Y53C12C    (II) contains 13A8 end (T10B9.4) overlaps T10B9 3' end
*Y55H10     (IV) contig 104 identical to F42A6 CYP25A5
*Y69H2      (V) same as C54E10 CYP33D3
*Y71G12     (X) contig 00174 same as CYP22
*Y73C8      (V) contig 93 CYP33C9
*Y75B12     (V) contig 03079 same as CYP34A1 and CYP34A2, T10H4
*Y80D3      (V) end of C54E10 (CYP33D3) and whole cm08B12 seq. (CYP42)
* Y97E10      (V) contig266 same as CYP32
*Y102F5     (X) same as CYP29A1
*Y108G3     (V) contig 541 CYP29A3 
*yk18a10    (V) D35162 partial C-terminal EST fragment matches F41B5 
                exactly CYP33C3
ZK177       (II) mitochondrial P450 CYP44
ZK1320.4    (II) Z46934 CYP13A10 overlaps Y53C12A
*ZK1325     (II) N-terminal of T10B9.4 current version of
                 ZK1325 is incomplete and does not have the end of
                 cosmid overlap CYP13A8

Unsorted	 1 P450 gene
F54E5       (?) contig 00150 CYP51 gene fragment.  Identical to human, rat 51
                This is probably a contamination and not a C. elegans sequence.
                C. elegans does not seem to have a CYP51 gene.

Total 75 genes and 6 pseudogenes on Sept. 22, 1998 genome ~84.4% complete and in GenBank
However Blast searchable database at Wash U. has 139 Mb seq in it so nearly the whole 
genome is there, just not polished yet.