Research Groups

Deepak Gaur

Metabolic Engineering

Group Leader

Research Interests and Description
Group Members

Shashi Kumar Rhode

International Centre for Genetic Engineering and Biotechnology
Aruna Asaf Ali Marg
110 067 New Delhi, India

E-mail: skrhodeicgeb.res.in, shashirhode@gmail.com
Office tel: +91-11-26741358/26742357 ext 475
Mobile: +91-999-99950544

Education

University of Delhi South Campus, Department of Genetics, New Delhi, India, PhD, 1998
University of Delhi North Campus, Department of Botany, New Delhi, India, MPhil, 1993
India Institute of Technology (IIT), Biosciences and Biotechnology, MSc, 1991
Meerut University, Zoology, Botany, Chemistry, BSc, 1988

Career History

2016, Group Leader, Integrative Biology: Metabolic Engineering, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India
2011-2015, Team Leader in advanced bio-energy research, Synthetic Biology and Biofuel Group, ICGEB, New Delhi, India
2009-2011, Research Scientist, Malaria Group, ICGEB New Delhi, India
2006-2009, Scientist, Yulex Corporation and USDA, Albany, CA, USA
2005-2006, Research Specialist, UC Berkeley, CA, USA
2001-2005, Research Associate, UCF, FL, USA
1998-2001, Research Associate, University of Virginia, Charlottesville, USA

Teaching Activity

External Examiner: Conducting BTech/MTech final year project viva on June 9-11, 2016, JayPee University of Information Technology, Solan, HP, India.
External Examiner:
Conducted M.Sc Biotechnology IV Sem. Project Viva-Voice on 5-6 December 2015, University of Banasthali, Jaipur, India.
External Examiner: Conducted M.Sc applied Microbiology & Biotechnology (AMBT), IV Sem. Project Viva-Voice on 24-25 June 2015, University of Banasthali, Jaipur, India.

Scientific Activity

  • Synthetic biology and Metabolic engineering of plant for drug biosynthesis and algae for higher biofuel values, biomass, and lipid
  • Focus on developing sustainable algae based biofuel (biodiesel)
  • DNA barcoding for algae and plant species identification
  • Chloroplast genome engineering of algae and higher plant species
  • RNAi mediated gene silencing in plant pests by expression of RNAs in chloroplasts
  • Genes stacking, Genome editing

Selected publications

Ahmad I, Kumar S. (2015). GM algae for higher biofuel values and environmental biosafety. Symposium Proceedings, Recent Advances in Biotechnology for food and Fuel, November 19-20, TERI IHC, New Delhi. P-68-76. doi:10.13140/RG.2.1.2941.3602.

Ahmad, I., Sharma, A., Daniell, H., Kumar, S. (2015) Altered Lipid Composition and Enhanced Lipid Production in Microalga by Introduction of Brassica Diacylglycerol Acyltransferase 2. Plant Biotechnology Journal, 13: 540-550.

Kumar, S. 2015. Algae for Biofuel Production: Biosafety and Risk Assessment. Collection of Biosafety Reviews 9, 52-75

Singh, D. Kumar, S., Daniell, H. (2015) Expression of Beta-glucosidase increases trichome density and artemisinin content in transgenic Artemisia annua plants. Plant Biotechnology Journal, doi: 10.1111/pbi.12476. [Epub ahead of print].

Kumar, S., Bhatnagar, R.K., Kranthi, K.R., Datta, S.K.  2014. The legal battle over field trials of GM crops. Nature India DOI:10.1038/nindia.2014.14

Heikrujam, M., Kumar, D., Kumar, S., Gupta, S.C., Agrawal, V.  (2014) High efficiency cyclic production of secondary somatic embryos and ISSR based assessment of genetic fidelity among the emblings in Calliandra tweedii (Benth.). Scientia Hort, 177, 63-70.

Shao, M., Kumar, S., Thomson, J.G. (2014) Precise excision of plastid DNA by the large serine recombinase Bxb1. Plant Biotechnology Journal 12, 322-329.

Saxena, B., Subramaniyan, M., Malhotra, K., Bhavesh, N.S., Potlakayala, S.D., Kumar, S. 2014. Metabolic engineering of chloroplasts for artemisinic acid biosynthesis and impact on plant growth. J Biosci 39, 1-9.

Truan, S., Cornish, K., Kumar, S. (2014) Photosynthetic response of in vitro guayule plants in low and high lights and the role of non-photochemical quenching in plant acclimation. Industrial Crops and Products 54, 266–271.

Ahmad, I., Fatma, Z., Yazdani, S., Kumar, S. (2013) DNA barcode and lipid analysis of new marine algae potential for biofuel. Algal Research. 2, 10-15.

Kumar, S., Baidoo, E., Hahn, F.M., Kahlon, T., Wood, D., McMahan, M.C., Cornish, K., Keasling, J., Daniell, H., Whalen, M.C. (2012) Remodeling the isoprenoid pathway in tobacco by expressing the cytoplasmic mevalonate pathway in chloroplasts. Metabolic Engineering 14: 19-28. DOI: 10.1016/j.ymben.2011.11.005

Turan, S., Cornish K., Kumar, S. (2012) Salinity Tolerance in Plants: Breeding and Genetic Engineering. Australian Journal of Crop Science 6: 1337-1348.

Singh, D., Singh, P.K., Chaudhary, S., Mehla, K., Kumar, S. Exome sequencing and advances in crop improvement. Advances in Genetics 79, 87-121.

Malhotra, K., Chhabra, G.K., Jain, R., Sharma, V., Kumar, S. (2012) Drought And Salinity Tolerant Biofuel Crops for The Thar Desert. In: N. Tuteja and S. Gill (eds.) Plant Acclimation to Environmental Stress, Springer Science, New York, NY 10013, USA, ISBN 978-1-4614-5000-9.

Kumar, S., Kahlon, T and Chaudhary, S. (2011) DNA barcodes for unmasking the adulteration in olive oil. Food Chemistry 127: 1335–1341

Kahlon T. and Kumar, S. Rice Bran A Rice Milling Byproduct As Value Added Health Promoting Food Product. Plant Biotechnology Symposium, 23-24 September 2010 at Sardar Vallabhbhai Patel University of Agriculture and Technology, Modipuram, Meerut.

Kumar, S., McMahan, M.C., Cornish, K. and Whalen, M.C. (2009) Comparative analysis of the complete sequence of the plastid genome of Parthenium argentatum and identification of DNA barcodes to differentiate Parthenium species and lines. BMC Plant Biology 2009, 9:131 doi:10.1186/1471-2229-9-131

Kumar, S. Chaudhary, S and Whalen M. (2008) DNA Barcoding for Genetic Identification of Plant Genera. In: A K Chauhan, Varma, A and Verma, N (eds.) Microbes for Human life, Text book of Molecular Biotechnology, pp. 305-318, I.K. International Publishing House Pvt. Ltd., New Delhi.

Daniell, H., Kumar, S. and Dufourmantel, N. (2005) Breakthrough in chloroplast genetic engineering of agronomically important crops. Trends in Biotechnology 23: 238-245. 

Daniell, H., Chebolu, S., Kumar, S., Singleton, M., Falconer, R. (2005). Chloroplast-derived vaccine antigens and other therapeutic proteins. Vaccine 23:1779-1783.

Kumar, S. and Daniell, H. Improvement of Cotton via Genetic Manipulation of the Chloroplast Genome. Beltwide Proceedings, USA, 2005.

Kumar, S., Dhingra, A. and Daniell, H. (2004) Plastid expressed betaine aldehyde dehydrogenase gene in carrot cultured cells, roots and leaves confers enhanced salt tolerance. Plant Physiology 136: 2843-2854.

Kumar, S., Dhingra, A. and Daniell, H. (2004) Stable transformation of the cotton plastid genome and maternal inheritance of transgenes. Plant Molecular Biology 56: 203-216.

Kumar, S. and Timko, M.P. (2004) Enhanced Tissue-Specific Expression of the Herbicide Resistance bar Gene in Transgenic Cotton (Gossypium hirsutum L cv. Coker 310FR) Using the Arabidopsis rbcS ats1A Promoter. Plant Biotechnology 21: 251-260.

Kumar, S. and Daniell, H. (2004) Engineering the chloroplast genome for hyper-expression of human therapeutic proteins and vaccine antigens in Recombinant Protein Protocols. Methods in Molecular Biology 267: 365-383.

Daniell, H., Cohill, P., Kumar, S. and Dufourmantel, N. 2004. Chloroplast genetic engineering. In: Daniell, H. and Chase, C. (eds) Molecular biology and biotechnology of plant organelles, pp. 423-468.  Kluwer Academic Publishers, Dordrecht.

Patents

Kumar, S., Singh, A.K. Method of Utilization of Carbon Concentration Mechanism in Micro-Algal Species to Increase Production of Lipids and Obtain Bio-Fuel. Indian Patent Application No: 2856/DEL/2015

Kang, B., McMahan, C.M., Whalen, M.C., Dong, N., Kumar, S. (2016). Engineering rubber production in plants. US 20140325699 (granted). WO/2014/152747 https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2014152747

 

 

ICGEB New Delhi

ICGEB Campus
Aruna Asaf Ali Marg
110 067 New Delhi
INDIA
Tel: +91-11-26741358/1007
Fax: +91-11-26742316
icgebicgeb.res.in

 

 

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