ICGEB launches a diagnostic kit for Celiac Disease

The commercial launch of the Diagnostic Kit for Celiac Disease developed at ICGEB New Delhi is taking place today, 28 October 2014, at ICGEB New Delhi, in the presence of Dr. Jitendra Singh, Hon. Minister of Science and Technology, Government of India.

The Department of Biotechnology, Government of India, has sponsored a collaborative programme between the Translational Health Science and Technology Institute (THSTI), the ICGEB, the All India Institute of Medical Sciences (AIIMS) and an industrial partner, J. Mitra and Co., for the development of  affordable, indigenous, rapid sensitive and specific diagnostic tests for Celiac Disease. 

Celiac disease (CD) is a lifelong disorder that results in damage to the lining of the small intestine in individuals when foods with gluten such as wheat, rye, and barley are eaten. The disease is therefore known as an autoimmune condition where the body forms antibodies against itself.

Navin Khanna heads the Mammalian Biology: Recombinant Gene Products lab at ICGEB New Delhi, where a recombinant clone for the production of antigen (human tissue transglutaminase -tTGA protein) has been developed. This “know-how” has been transferred to J. Mitra and Co, under DBT guidelines, with CD patients screened and samples provided by AIIMS/THSTI.

ICGEB research efforts in the area of in-vitro diagnostics have made significant impact on the public health in India and many developing countries, developing over 20 diagnostic kits to date, including kits for the detection of Hepatitis B, Hepatitis C, HIV and Dengue infections, being sold in over 40 countries. The World Health Organisation uses these diagnostics kits for their programs in several developing countries.

The Dengue diagnostic kit has been his most recent success story, as 12 million dengue tests have been sold in India. A company in China has commercialised Hepatitis B Vaccine and r-human insulin using clones developed by Dr. Khanna. This know-how has also been transferred to several developing countries. Current research efforts on dengue vaccine candidates are being supported by Wellcome Trust and NIH.



Dr. Navin Khanna, ICGEB New Delhi

Press Release

28/10/14 Celiac disease (CD) a lifelong disorder

Business Standard: Dr. Jitendra Singh Launches Celiac Disease Diagnostics Kits Commercially

BioSpectru: India gets its own diagnostic kit for Celiac diseases

Business line: First indigenously made diagnostic kit for Celiac disease

Press Information bureau: Dr. Jitendra Singh Launches First Indegenously Developed Diagnostic Test Kit for Intestinal
Disorder “Celiac Disease”


YouTube: Jitendra Singh launches affordable diagnostic kit for celiac disease

Further reading:

5/12/11 Forbes: India's Biotech Messiah

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