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[Last update: 14/08/07]
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What is it? What does it do?
The International Centre for Genetic Engineering
and Biotechnology conducts innovative research in life sciences
for the benefit of developing countries. It strengthens the research
capability of its Members
through training and funding programmes and advisory services
and represents a comprehensive approach to promoting biotechnology
internationally. The Centre is dedicated to advanced research
and training in molecular biology and biotechnology and holds
out the prospect of advancing knowledge and applying the latest
techniques in the fields of:
biomedicine; crop improvement; environmental protection/remediation;
biopharmaceuticals and biopestidice production.
ICGEB provides a scientific and educational
environment of the highest standard. It brings biotechnology
to developing countries by strengthening their research capabilities,
developing state-of-the-art research and training scientists
to the benefit of its Member States.
Located in Trieste, Italy, New Delhi,
India and Cape Town, South Africa, the Centre forms an interactive network with Affiliated
Centres in ICGEB Member States.
Facts and Figures
The ICGEB premises cover an area
of 7,000 sq.m. in Trieste
and 10,000 sq. m. in New
Delhi. These are state-of-the-art purpose built laboratories fully equipped with the most technologically advanced scientific instrumentation.
Composition
The Board of Governors,
made up of representatives from each Member State, the Council of Scientific Advisers,
composed of eminent scientists who oversee the scientific excellence
of the Centre, and the Secretariat which is constituted
by the Director-General, Prof. Franciso E. Baralle, the Directors of the
two Components, Prof. Mauro Giacca - Director
ICGEB Trieste, and Prof.
Virander S. Chauhan - Director
ICGEB New Delhi and
by the Director
Administration and External Relations, Mr. Decio Ripandelli.
At present more than 300 people from 28
different countries are working in the ICGEB laboratories
as research scientists, postdoctoral fellows, PhD students, research
technicians and administrative personnel.
Since 1999 all Member
States participate in the financing of ICGEB through a scale
of assessment adopted by the Board
of Governors at its third session. The Financial
Regulations (in PDF) of the Centre are available for consultation.
History
The International Centre for Genetic Engineering
and Biotechnology was launched in 1983, through the signing of
its Statutes (the international
treaty sanctioning its existence, deposited with the Secretary
General of the United Nations) by 26 countries during a Plenipotentiary
Meeting, held in Madrid.
The representatives of the Signatory
Countries met in Vienna in 1984 and decided that ICGEB would
be structured with two Components, one located in Trieste, Italy
(which will also be the Headquarters of the Centre), and one
in New Delhi, India as well as a network of Affiliated
Centres.
Pending the entry into force of the Statutes,
ICGEB started to operate in 1987 as a special programme of the
United Nations Industrial Development Organization (UNIDO).
The implementation of the programme was made possible through
funds provided by the Host Governments of Italy and India. The
Statutes of the Centre entered
into force on 3 February 1994 and, in accordance with Article
1, the ICGEB became an autonomous, intergovernmental organisation.
As at May 2006, ICGEB has 55 full Member States, a further 19 countries are still pending ratification of, or accession to, the Statutes of ICGEB.
ICGEB is part of the United
Nations System.
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Developing Knowledge Research and Development Focus at ICGEB
Research at ICGEB Trieste
Scientific activity focuses on several advanced
projects in current biomedical research. The research programmes include basic science projects such as control of gene expression, DNA replication, DNA repair and RNA processing; studies on human viruses such as HIV, HPV and rotavirus, moleuclar immunology, moleuclar genetics, experimental hematology (at the ICGEB
Outstation in Monterotondo, Rome) and human gene therapy.
Other Groups focus on projects in the fields of bacteriology and yeast genetics, protein structure and bioinformatics.
The ICGEB Outstation in Ca' Tron (Treviso) addresses experimental issues in the field of plant virology and bacteriology.
Research at ICGEB New Delhi
The two main research areas at
ICGEB New Delhi focus on mammalian and plant biology.
Biomedical projects are pursued in virology (hepatitis B an E
viruses, human immunodeficiency virus and SARS virus), immunology
(biology of the immune resonse and tuberculosis), structural
biology (development of synthetic antibiotics, crystal structure
determination of proteins and polypeptides) and in the field
of malaria both in basic research and vaccine and drug development.
In the plant biology area, research projects address the study
of insect resistance and biopesticidals abiotic and biotic plant
stresses and crop imporvement through biotransformation.
Core Facilities available
at ICGEB
Scientists at both ICGEB Components
have access to state of the art facilities in advanced optical
microscopy, proteomics, flow cytometry, viral vector production,
high-level biocontainment laboratories and greenhouses.
In Trieste
and New Delhi intense activity is carried out in the biotecnology
field for the development of technologies aimed at the production
of recombinant therapeutics and diagnostics.
Relationship with the Industrial
Sector
Policy guidelines
on the use of ICGEB-owned intellectual property rights and
know-how are in place with a view to fostering innovative approaches
for industrial relations at a global level and enhancing joint
ventures and other partner-oriented approaches for the commercialisation
of the results of research in biotechnology.
69 agreements and collaborations with industrial partners for training, transfer of technologies and patent licensing have been concluded in the past seven years.
Institutional Activities
ICGEB plays an important role in biosafety-related
issues and in the environmentally sustainable use of biotechnology.
The Centre provides an on-line, biobliographic database on Biosafety, a search
mechanism on risk assessment for the release of genetically modified
organisms (GMOs). This activity has now been expanded with the
new Biosafety
Outstation at Ca' Tron.
The Centre is active in enhancing the safe
and peaceful use of biotechnology and is promoting the adoption
of ethical codes for researchers working in life sciences.
In addition, technical advice is provided to Member States on request for
the formulation of national bioscience policy; definition of
research goals; development of national bioindustries, and the
establishment of national biotechnology laboratories.
Cooperation with other International Agencies
is promoted to harmonise and speed up projects of common interest.
Some of the Organisations with which ICGEB maintains close contact
and collaboration are:
Abdus Salam
International Centre for Theoretical Physic ICTP (Trieste)
Elettra synchrotron
(Trieste)
European Commission EC
European
Molecular Biology Laboratory EMBL
Food and Agriculture
Organization of the United Nations FAO
International
Atomic Energy Agency IAEA
International
Centre for Science and High Technology ICS (Trieste)
International School for Advanced
Studies SISSA (Trieste)
Organisation for Economic Co-operation
and Development OECD
The Academy of Sciences for the Developing World (Trieste)
United Nations Industrial Development
Organization UNIDO
United Nations
Environment Programme UNEP
United Nations
Educational, Scientific and Cultural Organization UNESCO
World Health Organization
WHO
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